Best Hillsborough County Grants for Nonprofits in Florida

The Regional Rural Development Grant Program

The FloridaCommerce Regional Rural Development Grant program was established by Section 288.018, Florida Statutes, to encourage rural communities to leverage limited resources by utilizing regional economic development organizations to develop and implement long-term strategies that will help:

• Attract new businesses;
• Grow existing businesses; and
• Build the innovative and adaptive capacity of rural leaders who are active in decision-making roles in their communities.

An organization may receive up to $50,000 or $250,000, if representing two or more rural counties, recommended by the Rural Economic Development Initiative and designated by the Governor.

The Recovery Housing Program (RHP)

In 2018, the United States Congress passed the SUPPORT for Patients and Communities Act (SUPPORT Act) to address substance use disorder prevention, recovery, and treatment. Section 8071 of the SUPPORT Act authorizes the Recovery Housing Program (RHP). RHP funds are allocated by the United States Department of Housing and Urban Development to allow states to provide stable, transitional housing for individuals in recovery from a substance use disorder. The RHP is a program within federal Community Development Block Grant (CDBG) programs, with rules modified by Federal Register Notice FR-6225-N-01.

Since 2020, FloridaCommerce has been awarded a total of $4,805,253 in RHP funding. FloridaCommerce's RHP Action Plan will guide the use of the allocation.

FloridaCommerce has identified a specific need for additional recovery housing and services for the veterans community within the state. The United States Department of Veterans Affairs FFY 2017 population estimates reflect that Florida has the third largest veteran population among all states in the nation.

To date, Governor DeSantis has awarded $1.6 million to provide transitional housing for Floridians and veterans recovering from substance abuse through RHP. The upcoming application cycle will result in awarding an additional $3.1 million for continued support through RHP.

Resilient Florida Grants

The Resilient Florida Program includes a selection of grants that are available to counties, municipalities, water management districts, flood control districts and regional resilience entities. To effectively address the impacts of flooding and sea level rise that the state faces, eligible applicants may receive funding assistance to analyze and plan for vulnerabilities, as well as implement projects for adaptation and mitigation. 

KBF Ski Racing Safety

The KBF helps alpine ski clubs around the country purchase safety equipment like netting and padding, and also contributes to venue improvement initiatives. Funding requests are reviewed through an annual grant cycle with an application process. Over the past decade, the Kelly Brush Foundation has purchased thousands of rolls of b-netting, supported trail widening projects, and helped with the purchase of other safety equipment. 

KBF Ski Racing Safety Equipment Grants are all matching grants–meaning that any grant awarded by the Kelly Brush Foundation will need to be matched by the ski club. We expect that clubs will join us in making safety a priority by fundraising or finding room in their budget for safety.

The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.

The BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR)—Formula Grants Program aims to support states and local governments in enhancing their DNA analysis capabilities. By providing funding for existing crime laboratories, this initiative seeks to increase the processing capacity for DNA samples, thereby reducing the backlog in forensic DNA analysis and ensuring timely entry into the Combined DNA Index System (CODIS). Applications are due by November 5, 2026.

The BJA FY 2026 Adult Treatment Court Program aims to enhance Adult Treatment Court operations, focusing on preventing overdoses and reducing substance use among high-risk adults in the criminal justice system. The program integrates judicial supervision, substance use disorder treatment, and recovery support services to improve outcomes for participants. This funding opportunity from the U.S. Department of Justice highlights the commitment to public safety and addressing critical issues like the opioid crisis.

About Us

The Wenner-Gren Foundation is a private operating foundation dedicated to providing leadership in support of anthropology and anthropologists worldwide.

Our Mission

The Wenner-Gren Foundation is committed to playing a leadership role in anthropology. We help anthropologists advance anthropological knowledge, build sustainable careers, and amplify the impact of anthropology within the wider world. We dedicate ourselves to broadening the conversation in anthropology to reflect the full diversity of the field.

Global Initiatives Grant

General

Since the program’s launch in 2020, the Wenner-Gren Foundation has funded a small number of initiatives that meet a need not already addressed by our other programs. Global Initiatives Grants help support innovative projects that benefit the discipline as a whole by creating the conditions for anthropologists to do better work. Over the years we have awarded initiatives in which a small amount of money has had a wide and lasting impact, building capacity for the discipline to thrive.

We are eager to receive applications from individuals based in countries, regions, and communities where anthropology is disadvantaged or under threat. Our total budget for this program is modest, so the competition is fierce.

In the past, we prioritized projects aimed at building capacity by addressing specific themes, including the impact of Covid-19 on anthropology, the struggle for racial justice in the discipline, the ethical treatment of human remains, and supporting paleoanthropology in East Africa.

From 2026–2030, Global Initiative Grants will be making a single award giving priority to innovative projects in public anthropology that are designed to reach broad, general audiences. Applicants may draw on any combination of anthropological tools, theories, and methods to share disciplinary knowledge in ways that are accessible, pioneering, and socially consequential.

Successful projects will push public anthropology in new directions. Initiatives may take the form of targeted, high-impact interventions responding to emerging crises and opportunities, or longer-term efforts to create the infrastructure needed to sustain public engagement beyond the grant period. Proposals seeking to establish enduring programs must provide a detailed and realistic plan for ongoing financial, technical, and administrative support.

Award Money

One grant of up to $80,000 will be awarded each year. Funding is nonrenewable. There is no limit to the duration of the grant.

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Bret A. Rosenthal Patient Assistance Fund

Patients diagnosed with cancer at a younger age often face greater financial burdens. This is a time in a patient’s life when they are raising a family, starting a career, or have not accumulated savings. For patients 49 and under, the Foundation administers the Bret A. Rosenthal Patient Assistance Fund grant program. This program is made possible by the generosity of the Rosenthal family.

Maternal Health Grant Program

Florida Blue Foundation is funding approximately $3 million for this grant program, offering four year grants. The total funding request for the grant period should fall within the range of $300,000 to $400,000, with an approximate annual allocation of $75,000 to $100,000.

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The Affordable Rural Cooperative (ARC) Energy Program, initiated by the Rural Utilities Service (RUS), aims to enhance rural electric systems through substantial funding of approximately $175 million. This initiative focuses on increasing emission-free nuclear power and improving transmission infrastructure efficiency, promoting long-term reliability and affordability. Eligible entities include electric cooperatives serving rural areas and their subsidiaries. The program aligns with the Inflation Reduction Act (IRA) to achieve significant reductions in greenhouse gas emissions, thus fostering a sustainable energy future.

The Drexel Fund Founders Program is a one-year paid fellowship that helps outstanding leaders already on the path to launching a school continue to plan and open an innovative and effective private school in one of The Drexel Fund’s target states: Arizona, Florida, Indiana, Iowa, North Carolina, Ohio, Tennessee and Wisconsin. The tenth cohort of the Founders Program is designed for entrepreneurs who will begin the fellowship in Summer 2027 and be ready to launch a new private school in Fall 2028.Through the fellowship, school founders will develop their school’s education model and finalize the nuts and bolts of their school launch, including board and budget development, market analysis, facility location, student recruitment and staff hiring. Founders will create a plan that will make it possible for their school to achieve top-tier results for children while maintaining a sustainable financial model.

Greenawalt Foundation

Our Mission

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Community Grant

The Greenawalt Foundation extends its commitment to opportunity and well-being through community grants that support nonprofit organizations serving women, children, and vulnerable populations. These grants focus on programs that promote safety, stability, and self-sufficiency, including initiatives supporting domestic violence recovery, foster care, the working poor, and animal welfare. Foundation support strengthens the social fabric of communities and expands access to essential resources for those in need. Through these efforts, the Foundation helps build stronger, more compassionate communities where individuals and families can thrive.

Areas of Support

We focus our community grants on initiatives that align with our mission of compassion, opportunity, and empowerment. Areas of support may include:

• Domestic violence prevention and survivor support
• Programs for women and children
• Family assistance and poverty relief initiatives
• Foster care, youth development, and educational support
• Animal welfare and community-based rescue programs

Greenawalt Foundation

Building Stronger Communities

At The Greenawalt Foundation, we believe that opportunity is the foundation of prosperity. By supporting organizations that educate, train, and empower people in the trades, we’re helping to build a stronger, more sustainable future for all.

Skilled Trades Grant Opportunities

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Eligible Grant Categories

• Skilled Trades Training Support
• Pre-Apprenticeship or Apprenticeship Programs
• Youth Career Exploration Camps

Seeding Research, Networking, and Capacity Building at Minority-Serving Institutions

Introduction & Purpose

RWJF is committed to ensuring everyone has a fair and just opportunity to be as healthy as possible. To achieve this goal, we support research that examines the historical and systemic factors that cause health inequities. Some of those determinants are poverty, discrimination, and limited access to quality education, housing, safe environments, and healthcare. As attacks on data and academic freedom and ongoing funding cuts to federal health equity research and programs continue, philanthropy’s work to achieve fair and equitable health, including a more equitable research funding ecosystem, is more important than ever. While philanthropic support for Minority-Serving Institutions (MSIs) has increased in recent years, there is more to be done to rectify historical disparities in funding. 

This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.

Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity. 

RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.

Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.

Hurricane Response Marine Debris Removal Fund

2027 Request for Proposals

National Fish and Wildlife Foundation (NFWF) and the National Oceanic and Atmospheric Administration (NOAA) established the Hurricane Response Marine Debris Removal Fund to support projects to assess, remove, and dispose of marine debris in and around coastal communities impacted by hurricanes and other episodic storm events.

The Hurricane Response Marine Debris Removal Fund will award grants to remove damaging marine debris from coastal areas of communities impacted by hurricanes or other natural disasters. Priority will be placed on debris removal efforts that reduce impacts on communities and industry as well as prevent further harm to habitats and fish and wildlife populations. Funding has been made available by the FY 2025 American Relief Act, P.L. 118-158.

The Hurricane Response Marine Debris Removal Fund will award up to $11 million in grants in 2027. While there is no minimum or maximum expected award amount, funding request amounts should be appropriate relative to the overall scale and impact of the project.

The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of biological processes driven by somatic mutations in human tissues through innovative technology development. Since its inception in 2023, the program has produced multi-omic datasets from human tissues representing all germ layers. The NIH is now advancing to Stage 2, focusing on collaborative efforts to refine and implement validated technologies for somatic mutation detection and functional interpretation, promoting rigorous and cost-effective methodologies.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR) Competitive Grants Program aims to enhance the capacity of state and local government crime laboratories for processing DNA samples. This program focuses on using DNA technology to improve forensic efficiency and implement Rapid DNA in booking stations. It targets jurisdictions with operational challenges, ensuring fair access to funding. Eligible agencies can apply for both competitive and formula CEBR funding.