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Looking for grants for 501(c)(3) nonprofit organizations working in DeSoto County, Florida? Find the perfect grant for your nonprofit on Instrumentl
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$2.70B
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$5K
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Our Story
As a public charity dedicated to serving the needs of our region, everything we do here is about the community.
The notion of a community caring for its own is written in our organizational DNA. Our foundation was created in 1995 with proceeds from the sale of The Venice Hospital, a community hospital that had been founded by local citizens more than four decades earlier. We are a collection of charitable funds created by individuals, families, organizations, and corporations to support their favorite causes in our region and around the world. Over 850 generous philanthropists call Gulf Coast home. Together with our donors, we have invested over $650 million in grants and impact in the areas of health and human services, civic and economic development, education, arts and culture, and the environment.
GCCF: Catalytic Grants
Supporting bold, collaborative projects that create lasting regional impact. These grants typically exceed $25,000.
Funding areas include: Arts & Culture, Civic & Economic Development, Education, Environment, and Health & Human Services
2026-27 Innovative Service Development (ISD) Grant Opportunity
The Florida Commission for the Transportation Disadvantaged is pleased to announce the release of the Innovative Service Development (ISD) Grant Program application package for Fiscal Year 2026–2027.
This is a competitive grant program for Community Transportation Coordinators and Non-Traditional Transportation Service Providers. Anticipated total available funding is $6 million, contingent upon legislative authority and Governor’s approval.
This funding opportunity supports projects that test new transportation services that improve the cost-effectiveness, efficiency, and accessibility of transportation services for transportation disadvantaged individuals.
Introduction
The Transportation Disadvantaged Trust Fund is administered by the Florida Commission for the Transportation Disadvantaged (CTD) in accordance with Section 427.0159, Florida Statutes (F.S.). The Trust Fund provides a dedicated funding source to support the Commission’s statutory responsibilities and is appropriated annually by the Legislature for the state fiscal year (July–June).
For Fiscal Year 2026–2027, the Commission anticipates a $6 million appropriation to support the Innovative Service Development (ISD) Grant Program.
The ISD Grant Program supports projects that improve the cost-effectiveness and efficiency of transportation services. Grant funds are limited to reimbursing a portion of eligible transportation disadvantaged passenger trips. Grantees must provide services prior to submitting invoices for reimbursement, which will be issued on a per-trip and/or mileage basis.
Funded projects may include, but are not limited to:
Florida Small Cities Community Development Block Grant Program
Overview
The Community Development Block Grant (CDBG) Program is a federal program that provides funding for housing and community development activities. Congress created the program when it passed the Housing and Community Development Act of 1974.
The program, which is administered by the United States Department of Housing and Urban Development (HUD), consists of two components:
FloridaCommerce administers the State Program in Florida through the Small Cities CDBG Program. This is a competitive grant program that awards funds to units of local government in small urban and rural areas. FloridaCommerce receives between 18 and 26 million dollars annually from HUD to award subgrants to eligible units of local government.
The program provides an excellent opportunity for communities to obtain funds for projects that they cannot otherwise afford. CDBG funds can also provide administrative support for local governments that may not have the staffing resources necessary to administer their projects. Examples of CDBG-funded projects include:
Small Cities Community Development Block Grant Application Cycle
Funding is available for the Neighborhood Revitalization, Housing Rehabilitation, and Commercial Revitalization program areas. Non-entitlement units of local government are eligible to apply for funding in any of the three program areas if they have an open CDBG subgrant in one of the three areas.
FloridaCommerce also has funding available in the Economic Development program area for job creation and/or retention activities. Non-entitlement units of local government that have an open Neighborhood Revitalization, Housing Rehabilitation, Commercial Revitalization, or Economic Development subgrant are eligible to apply for Economic Development funding.
The Selby Mission
By investing in people through academic scholarships and supporting capital projects of local organizations, we look beyond what is and enable change for what can be.
Traditional Grants
The William G. and Marie Selby Foundation awards “traditional grants” twice each year.
Organizations with budgets greater than $300,000 that primarily serve Sarasota, Manatee, Charlotte and DeSoto counties have the opportunity to apply.
The Selby Foundation invests in capital support that will help nonprofits achieve more for those they serve.
2025 Urban & Community Forestry Natural Disaster and Recovery Supplement
The scope of this program is designed to improve and reestablish urban forests in 56 peninsular Florida counties that were negatively impacted by Hurricanes Idalia, Helene, and Milton. These efforts will emphasize not just tree planting but also pruning and efforts to enhance urban forest resiliency through strong planning methods. The primary purpose is to not just replace lost canopy, but to ensure that the urban forest is more resilient to future storms, enhancing the likelihood of long-term recovery. The State of Florida anticipates an allocation of $1,500,000 to applicants through this funding opportunity.
INTRODUCING “SAM” (SMALL AND MIGHTY)
The William G. and Marie Selby Foundation is excited to introduce SAM (Small And Mighty) grant program!
This program was developed to meet the needs of small-scale, non-profit organizations within our community (Charlotte, DeSoto, Manatee, and Sarasota counties), and be responsive and reactive to those needs.
To qualify for this program, organizations must have less than $300,000 in annual operating expenses. Additionally, the request must be for a capital expenditure(s).
Highlights of SAM Include:
Areas of Interest
The Selby Foundation specializes in supporting area non-profits with capital grants. Capital grants support the construction, acquisition and/or renovation of facilities, as well as the purchase of equipment or software. They may also include the costs of related technical services. Projects focusing on education, human services, arts and community projects including history, science, and/or the environment will be given top priority.
Selby funding is generally intended to assist organizations in pursuing strategic goals by leveraging support from a broad base of constituents. As such, applicants who can demonstrate a variety of other funding sources for their project, and/or those who request less than 10% of the total project cost are usually given priority for approval. Organizations are encouraged to compile a list of their future needs and meet with Foundation staff to explore possible fits.
About Samaritan Health Services
We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of their ability to pay.
Health Education Scholarships
One of the many keys to maintaining a healthy, prosperous community is ensuring a sustainable supply of excellent health care providers. To achieve this, Samaritan Health Services offers numerous scholarships to local students pursuing careers as doctors, nurses, nurse practitioners and physician assistants, as well continuing education or specialty training for current medical providers.
Each year, Samaritan awards more than $25,000 in scholarships for health care education to ensure the communities we serve receive the best care possible well into the future.
North Lincoln Hospital Foundation Medical Training Scholarship
The North Lincoln Hospital Foundation is committed to supporting the growth and development of healthcare professionals. Through the Medical Training Scholarship program, eligible applicants can receive up to $1,500 to help cover tuition costs for certification programs or degrees in nursing, diagnostic imaging, laboratory sciences, and other medical or technical fields.
About Samaritan Health Services
We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of their ability to pay.
Health Education Scholarships
One of the many keys to maintaining a healthy, prosperous community is ensuring a sustainable supply of excellent health care providers. To achieve this, Samaritan Health Services offers numerous scholarships to local students pursuing careers as doctors, nurses, nurse practitioners and physician assistants, as well continuing education or specialty training for current medical providers.
Each year, Samaritan awards more than $25,000 in scholarships for health care education to ensure the communities we serve receive the best care possible well into the future.
Mary Decker Scholarship
The North Lincoln Hospital Foundation is honored to offer scholarships to aspiring health care professionals who live in Lincoln County. The Mary Decker Scholarship Fund was created in 2006 with the support of many friends and colleagues in the health care community and the North Lincoln Health District Board. The intent is to honor and recognize Mary’s many years of service to her community and the state by providing scholarships to further career development in health care. The fund provides scholarships for qualified applicants to pursue a degree in a medical or paramedical field at an accredited school of their choice.
Literary Arts Fund
Grants Overview
The Literary Arts Fund will award at least $50 million in grants to the nonprofit literary arts field over the next five years, concluding in 2031.
With a short timeline, the fund’s grantmaking has a strategic focus on the areas of the literary arts ecosystem where it determined it could have the greatest impact— that is: supporting independent U.S.-based literary arts nonprofits whose primary mission is directly serving adult writers of creative nonfiction, fiction, poetry, and hybrid works in making their artistic work and sharing it with readers outside of school and academic settings. Please review the fund’s full eligibility requirements to learn more.
Innovation project grants provide funding to literary arts nonprofits for projects that may be collaborative and that aim to address critical challenges in one or more literary arts nonprofit organizations, presses, or publications that, if improved, would directly benefit creative writers’ artistic work and ability to share it with readers and audiences. These grants are disbursed to nonprofits in a single payment and intended for use during the project period.
About Samaritan Health Services
We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of their ability to pay.
Health Education Scholarships
One of the many keys to maintaining a healthy, prosperous community is ensuring a sustainable supply of excellent health care providers. To achieve this, Samaritan Health Services offers numerous scholarships to local students pursuing careers as doctors, nurses, nurse practitioners and physician assistants, as well continuing education or specialty training for current medical providers.
Each year, Samaritan awards more than $25,000 in scholarships for health care education to ensure the communities we serve receive the best care possible well into the future.
Gribler Loving Trust Nursing Education Scholarship
Each year, the Pacific Communities Health District Foundation awards the Gribler Loving Trust Nursing Education Scholarship to three students who live in Lincoln County, are pursuing a degree in nursing and who intend to practice in the community when they graduate. Up to $3,000 is awarded to each student and students who receive the scholarship are eligible to apply for a second year.
The scholarship is awarded in honor of Bill and Olga Gribler, Newport residents since 1947. Bill taught music, providing entertainment throughout the community, and Olga worked for the phone company and later the Bank of Newport. They established this generous scholarship to help address the ongoing need for quality nurses in the region.
Purpose
The intent of this scholarship is to assist a resident from Lincoln County, Oregon:
Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus.
Robert Woolley Scholarship
Open to graduating seniors from Stanislaus County attending a four-year university to study horticulture.
Award Amount:
About Samaritan Health Services
We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of their ability to pay.
Health Education Scholarships
One of the many keys to maintaining a healthy, prosperous community is ensuring a sustainable supply of excellent health care providers. To achieve this, Samaritan Health Services offers numerous scholarships to local students pursuing careers as doctors, nurses, nurse practitioners and physician assistants, as well continuing education or specialty training for current medical providers.
Each year, Samaritan awards more than $25,000 in scholarships for health care education to ensure the communities we serve receive the best care possible well into the future.
Virginia Welch Scholarship
Each year the Good Samaritan Regional Medical Center Auxiliary awards the Virginia Welch Scholarship to students planning to pursue a career in a medically-related field. The scholarship is named in honor of Virginia Welch, a head nurse who became Good Samaritan’s administrator in 1951 and served until 1967. To date, more than $320,000 has been awarded to students pursuing a career in health care.
High school seniors, undergraduate and graduate students currently enrolled in, or accepted to, a program to pursue a career in a medically-related field in a hospital setting are eligible to apply.
About Samaritan Health Services
We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of their ability to pay.
Health Education Scholarships
One of the many keys to maintaining a healthy, prosperous community is ensuring a sustainable supply of excellent health care providers. To achieve this, Samaritan Health Services offers numerous scholarships to local students pursuing careers as doctors, nurses, nurse practitioners and physician assistants, as well continuing education or specialty training for current medical providers.
Each year, Samaritan awards more than $25,000 in scholarships for health care education to ensure the communities we serve receive the best care possible well into the future.
Nurse Education Scholarship
The Nurse Education Scholarship is intended to provide financial support for the continued education of an individual who desires to further their career in the nursing field. The scholarship’s purpose is to support caregivers and Certified Nurse Assistants (CNA) who are pursuing ongoing education. The funds will be sent directly to the college for the student’s tuition and other expenses.
Literary Arts Fund
Grants Overview
The Literary Arts Fund will award at least $50 million in grants to the nonprofit literary arts field over the next five years, concluding in 2031.
With a short timeline, the fund’s grantmaking has a strategic focus on the areas of the literary arts ecosystem where it determined it could have the greatest impact— that is: supporting independent U.S.-based literary arts nonprofits whose primary mission is directly serving adult writers of creative nonfiction, fiction, poetry, and hybrid works in making their artistic work and sharing it with readers outside of school and academic settings. Please review the fund’s full eligibility requirements to learn more.
General Operating Grants Applications 2026 Guide
Background
The Literary Arts Fund was established in 2025 to dramatically increase funding for and the visibility of the nonprofit literary arts field toward ensuring a healthy and more robust U.S. literary culture in support of creative writers. The fund will award at least $10 million in grants to the nonprofit literary arts field in each of the next five years, concluding in 2031. The first open call is for 2026 general operating grant applications.
Looking for DeSoto County grants for nonprofits?
Read more about each grant below or start your 14-day free trial to see all DeSoto County grants recommended for your specific programs in Florida.
What's the typical amount funded for Florida?
Grants are most commonly $127,766.
What's the total number of grants in DeSoto County Grants for Nonprofits year over year?
In 2024, funders in Florida awarded a total of 120,990 grants.
Among all the DeSoto County Grants for Nonprofits given out in Florida, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.
1. Philanthropy, Voluntarism & Grantmaking Foundations
2. Education
3. Human Services
How is funding for DeSoto County Grants for Nonprofits changing over time?
Funding has increased by 4.30%.
How does grant funding vary by county?
Miami Dade County, Orange County, and Hillsborough County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Miami Dade County | $5,036,107,623 |
| Orange County | $3,251,041,805 |
| Hillsborough County | $2,859,448,977 |
| Broward County | $2,438,211,409 |
| Palm Beach County | $2,225,921,170 |