Best Holmes County Grants for Nonprofits in Florida

Pershing Square Lotus Award for Ovarian Cancer Research

The Pershing Square Foundation (PSF) has worked across sectors to catalyze innovative approaches to the most difficult problems. Talented individuals have always been at the center of our approach. We aim to support leaders who transform systems, embrace new paradigms, and have an innate drive to make an impact.

PSF has funded pioneering cancer researchers through the Pershing Square Sohn Cancer Research Alliance for over a decade and supported women’s health initiatives in New York City. Through this Request for Proposals (RFP), PSF aims to combine these two priority areas of women’s health and cancer to shine a light on one of the most understudied and underfunded cancers—ovarian cancer. Ovarian cancer is the deadliest gynecologic cancer, with 80% of women diagnosed at an advanced stage. Only 27% of women diagnosed during an advanced stage survive for five years. Ovarian cancer remains a disease with a poor prognosis due to limited early detection and treatment options.

PSF supports research efforts by 

• deploying capital quickly, 
• funding high-risk, high-reward ideas, 
• bringing new perspectives into a field, 
• encouraging collaboration, and 
• leveraging our vast network. We challenge our scientific partners to think creatively and across silos, to spur innovation to fight ovarian cancer.

Through the Pershing Square Lotus Award for Ovarian Cancer Research, PSF is looking for investigators who are either already working on a promising project in ovarian cancer or in another type of cancer that could have an impact on ovarian cancer. Grantees each receive $250,000 a year for three years, totaling $750,000.

Researchers who are not studying ovarian cancer are encouraged to apply and required to find a collaborator with experience in ovarian cancer research.

This award aims to 

• inspire investigators with unique expertise to apply their knowledge to ovarian cancer and 
• empower ovarian cancer researchers to pursue their boldest, most innovative ideas. Facing a disease where too few have survived to-date, PSF ultimately aims to create a culture around ovarian cancer that offers women hope, akin to the breast cancer community. PSF is passionate about changing outcomes for tens of thousands of women a year and is hopeful that future scientific discoveries will allow for more survivors who can share their stories for years to come.

Disabled Veterans National Foundation

The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.

Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.

Veterans Food Assistance Program

It is our goal to ensure that no veteran goes hungry by providing essential food assistance and household support, fostering stability and well-being in the lives of our veterans and their families.

The Veterans Food Assistance Program (VFAP) is designed to provide a one-time grant of essential food and household support to veterans and their families, ensuring no veteran goes hungry. With the rising cost of living, especially food prices due to inflation, this program offers a much-needed lifeline to those who have served our country. Once approved, the DVNF program team will handle the shopping for you.

The Veterans Food Assistance Program provides a one-time grant per household to support different family sizes, given the rising cost of food:

• Married Veterans Grant Allowance
  • Married - No Children up to $250
  • Married - 1 Child up to $300
  • Married - 2 Children up to $450
  • Married - 3+ Children up to $500
• Single Veterans Grant Allowance
  • Single - No Children up to $200
  • Single - 1 Child up to $300
  • Single - 2 Children up to $350
  • Single - 3+ Children up to $450

The Agriculture Innovation Center Grant Program aims to support Agriculture Innovation Centers by providing grants that facilitate technical assistance to agricultural producers. This initiative focuses on enhancing the marketing of value-added agricultural products, ultimately fostering growth in the agricultural sector. Funded by the USDA's Rural Business-Cooperative Service, this program is designed to empower producers and promote innovation in agricultural practices.

About Boeing

A leading global aerospace company and top U.S. exporter, Boeing develops, manufactures and services commercial airplanes, defense products and space systems for customers in more than 150 countries. Our U.S. and global workforce and supplier base drive innovation, economic opportunity, sustainability and community impact. Boeing is committed to fostering a culture based on our core values of safety, quality and integrity.

The Employees Community Fund (ECF) of The Boeing Company

One of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has empowered employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites provide combined employee donations to nonprofits in their communities through ECF grants.

Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.

Puget Sound Chapter

The Employees Community Fund (ECF) of Boeing Puget Sound is a pooled fund consisting of recurring payroll contributions from generous Boeing employees. It funds local nonprofits that help thousands of families and individuals in the Puget Sound region where Boeing employees live and work.

ECF focus areas

ECF makes grants to 501(c)(3) Health & Human Service nonprofits such as food banks, job-training programs, shelters, transitional housing, mental health services, and low-income medical clinics. ECF seeks the direct client benefit of each grant to ensure that our employees’ contributions directly help those in need.

ECF funding criteria

ECF has two distinct grant categories – Supporting Grants and Capital Campaign Grants.

ECF of Boeing Company: Puget Sound Chapter Supporting Grants

Consideration is given to nonprofits/agencies that are performing well and are seeking to upgrade, replace or modify elements of their infrastructure.

• Supporting grants cannot exceed $50,000. The requested amount cannot be more than 10% of an agency’s gross annual revenue.
• Supporting grants will be considered only for agencies benefiting residents in the Puget Sound Region.
• Supporting grants help agencies continue to effectively provide services through enhanced direct client benefit by aiding them in procuring and/or paying for items such as:
  • Equipment (ex. office, kitchen, industrial, furniture, etc.)
  • Vehicles used to support clients and/or transport food and/or goods (cost of vehicle and accommodations, tax, and licensing only; operating expenses, such as insurance, fuel, etc. is not allowed)
  • Phone systems
  • Cell phones for direct client use
  • Remodels and/or renovations (must hold at least a 10-year lease or own the building)
  • Purchase or construction of new buildings
  • Computers or tablets for direct client benefit and/or use
  • Software for direct client benefit and/or use (ex. Augmentative and alternative communication (AAC) device)
  • Information Technology expenses, without which procured tools would not work
  • External improvements for client safety (i.e. security system, exterior lighting, improved ADA accessibility, new or refinished pavement or concrete)
• Supporting grants which are accepted must be spent as approved within nine (9) months.

Presser Foundation

Passionate about music, Theodore Presser wanted to give back to it. When he died in 1925, he had been widowed twice without any children. The bulk of his fortune was left to The Presser Foundation, which was formally established 14 years after his death. From 1995 to June 2021, The Presser Foundation gave more than $80 million to music organizations, undergraduate and graduate music students, and retired music teachers.

Originally, the Foundation sought to promote the causes of musical education and musical philanthropy by providing scholarships for promising students, supporting the construction of buildings for music organizations, and directing aid to retired music teachers. Over time, the Foundation has evolved to support a broad array of music genres, expand its grantmaking areas, convene its nonprofit partners at special events, and collaborate with fellow funders, while continuing to follow the original intent and wishes of Theodore Presser.

Assistance to Music Teachers

Theodore Presser, mindful of his own early struggles in the profession, was committed to the support of music teachers. He also felt a sense of gratitude for the thousands of teachers who were the primary customers of his music publication business. In 1906, he established the Presser Home for Retired Music Teachers in Philadelphia. When it was no longer practical to maintain an independent facility, the Foundation created the Assistance to Music Teachers Committee to carry on its basic mission of financial support for retired teachers with financial need.

Typically, the Foundation provides modest financial assistance and/or help with the cost of medical insurance. Awards are made to individuals living in the United States whose primary occupation was as a teacher of music. To be considered for Assistance, applicants must be nominated by a music institution for consideration. 

The Kelley Foundation

The Kelley Foundation was established by Robert and Judy Kelley and their daughter Marla. The Kelleys are native Oklahomans and longtime residents of Southern Oklahoma.

The foundation is primarily focused on humanitarian projects in Oklahoma, with an emphasis on Southern Oklahoma. Our mission is to develop and strengthen our community, state, and nation by providing essential resources to those in need.

The Kelley Foundation Grant

The Kelley Foundation is a private, charitable foundation, incorporated under the laws of the State of Oklahoma and operated exclusively for providing support through its gifts and grants to religious, charitable, scientific, and educational institutions which are qualified under section 501(c)(3) and which are not private foundations within the meaning of section 509(a) of the Internal Revenue Service Code.

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

The State Recreational Boating Safety (RBS) Grant Program, administered by the US Department of Homeland Security's U.S. Coast Guard, aims to enhance safety and enjoyment on America's waterways. This federal program provides grants to designated state agencies to reduce boating accidents, injuries, and fatalities. Although not open to the public, it plays a critical role in ensuring safe recreational boating experiences by implementing effective safety measures, thereby promoting public welfare and environmental protection.

The project titled 'Aquatic Fauna Response to Ecosystem Restoration in Southwest Florida' aims to assess the effects of the Comprehensive Everglades Restoration Plan (CERP) on aquatic fauna. It will utilize a Monitoring and Assessment Plan (MAP) to evaluate responses of aquatic communities and inform future restoration efforts. This initiative is crucial for documenting CERP benefits and guiding further ecosystem restoration, ultimately benefiting the public by tracking progress in ecological recovery.

The Cancer Prevention and Control Programs aim to eliminate cancer through collaborative efforts among state, territorial, and tribal organizations. Funded by the CDC, this program supports initiatives such as breast and cervical cancer screening, cancer control planning, and cancer surveillance. By fostering partnerships and community involvement, the program seeks to improve health outcomes and achieve the mission of 'All People Free of Cancer.' This comprehensive approach ensures that resources are effectively coordinated to address the cancer burden in communities.

This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.

The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.

The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance understanding of biological processes and disease mechanisms due to somatic mutations in human tissues. Since 2023, it has produced multi-omic datasets from various human tissues. The NIH plans to advance this initiative by establishing the National Somatic Mosaicism Commons Data Analysis & Organizational Center, which will oversee data management, develop analytical tools, and provide training to facilitate research and clinical applications.

The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to uncover biological processes and disease mechanisms influenced by somatic mutations. Since its inception in 2023, it has produced valuable multi-omic datasets from diverse human tissues. The upcoming Stage 2 Genome Characterization Centers will focus on understanding the impact of these mutations in both healthy and clinically significant samples, enhancing our knowledge of somatic mosaicism's role in human health and disease.

In collaboration with Cummins Inc., the American Library Association (ALA) invites applications from U.S. public libraries to participate in A Year of STEM, 12 months of curated STEM programming to foster curiosity and STEM-mindedness in early childhood learners across the country. 

Twenty-five libraries will be chosen to participate in A Year of STEM, receiving professional development to prepare them for the project, copies of a newly created A Year of STEM programming guide developed by librarian advisors, a $5,000 programming stipend, four STEM kits (to be delivered quarterly), and support from ALA’s Public Programs Office staff throughout the project implementation period.

LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.  

The DOE Quantum Genesis Q Competition aims to accelerate the development of fault-tolerant quantum computing capabilities essential for scientific research. This initiative invites proposals from domestic entities to create viable plans for the Quantum Genesis program, aligning with national scientific goals. The competition serves as a foundational effort to scale quantum technologies and enhance scientific workflows, fostering innovation and collaboration as the nation progresses into a new era of computational power.

The Technology Development Program by the US Department of Health & Human Services focuses on advancing technology research from proof-of-concept to prototype development. This initiative prioritizes innovation to enhance biomedical research, emphasizing technological improvements without the inclusion of biological hypothesis testing. Eligible projects should aim at significant technological advancements to maximize impact in the field.

The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.

The FY2026/2027 Community Compass Technical Assistance and Capacity Building Program provides competitive grants to organizations capable of delivering technical assistance (TA) to communities served by HUD. With up to $86 million available, recipients are expected to develop educational tools, collaborate with HUD, and show a strong record of performance. This initiative aims to enhance community systems, support high-priority projects, and ensure effective training delivery, fostering impactful outcomes across the nation.

The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.

The National Endowment for the Humanities invites K-12 teachers and higher education faculty to apply for the Landmarks of American History and Culture and Summer Institutes program. This initiative aims to enhance humanities education through professional development opportunities, fostering a deeper understanding of historical and cultural landmarks. Participants will engage in enriching experiences designed to improve teaching practices and student learning outcomes in the humanities.

Springs and Watershed Restoration Program

Funding for land acquisition and capital projects that protect the quality and/or quantity of water from springs. Project proposals are initially submitted to the corresponding jurisdictional Water Management District for review.

DWRA's Springs and Watershed Restoration Program works closely with the water management districts, local governments and other stakeholders to identify and implement springs projects that achieve restoration goals.

The Regional Rural Development Grant Program

The FloridaCommerce Regional Rural Development Grant program was established by Section 288.018, Florida Statutes, to encourage rural communities to leverage limited resources by utilizing regional economic development organizations to develop and implement long-term strategies that will help:

• Attract new businesses;
• Grow existing businesses; and
• Build the innovative and adaptive capacity of rural leaders who are active in decision-making roles in their communities.

An organization may receive up to $50,000 or $250,000, if representing two or more rural counties, recommended by the Rural Economic Development Initiative and designated by the Governor.

The Recovery Housing Program (RHP)

In 2018, the United States Congress passed the SUPPORT for Patients and Communities Act (SUPPORT Act) to address substance use disorder prevention, recovery, and treatment. Section 8071 of the SUPPORT Act authorizes the Recovery Housing Program (RHP). RHP funds are allocated by the United States Department of Housing and Urban Development to allow states to provide stable, transitional housing for individuals in recovery from a substance use disorder. The RHP is a program within federal Community Development Block Grant (CDBG) programs, with rules modified by Federal Register Notice FR-6225-N-01.

Since 2020, FloridaCommerce has been awarded a total of $4,805,253 in RHP funding. FloridaCommerce's RHP Action Plan will guide the use of the allocation.

FloridaCommerce has identified a specific need for additional recovery housing and services for the veterans community within the state. The United States Department of Veterans Affairs FFY 2017 population estimates reflect that Florida has the third largest veteran population among all states in the nation.

To date, Governor DeSantis has awarded $1.6 million to provide transitional housing for Floridians and veterans recovering from substance abuse through RHP. The upcoming application cycle will result in awarding an additional $3.1 million for continued support through RHP.