Best Inyo County Grants for Nonprofits in California

About Community Alliance with Family FarmersOur mission is to build sustainable food and farming systems through policy advocacy and on-the-ground programs that create more resilient family farms, communities, and ecosystems. CAFF’s core values form the foundation on which we conduct our programs and activities. The values support our work, how we interact with each other, and how we fulfill our mission.

About California Underserved and Small Producer ProgramThe California Underserved and Small Producer (CUSP) Program is designed to facilitate support for small and medium scale California agricultural producers, or small and medium scale Socially Disadvantaged Farmers and Ranchers (SDFR’s) through technical assistance with business planning and financial and marketing strategies, and also provides direct farmer grants for drought relief for those same priority groups. Funding:

• Farmers can receive up to $20,000 in CUSP funding in a 12-month period, regardless of the granting organization(s).
• Eligible producers may receive up to $20,000 in CUSP Drought Relief funds as well as up to $20,000 in CUSP Extreme Weather Relief funds (for a total of up to $40,000) within a 12-month period (from date of CDFA approval/verification)

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.

T7 Social Impact GrantsThe T.D. Jakes Foundation (TDJF), in partnership with Wells Fargo, is proud to launch the Social Impact Grant Challenge, a transformative funding opportunity designed to identify, support, and amplify nonprofit organizations creating meaningful change in communities across the United States.

Designed around the T.D. Jakes Foundation's pillars of service (Educational Access & Workforce Readiness, financial inclusion, and community transformation and well-being), the Challenge seeks innovative nonprofit organizations that are addressing critical social issues through impactful, scalable, and sustainable solutions.

Finalists selected through this process will have the opportunity to showcase their organization through a live presentation at the inaugural Thriving Seven (T7) Summit, taking place November 12 –14 in Atlanta, Georgia. In addition to competing for grant funding, finalists will gain national visibility for their work and connect with nonprofit leaders, funders, and changemakers from across the country.Grant Funding: A total of $1,500,000 in grant funding is anticipated to be awarded: 

• One (1) - $500,000 grant
• One (1) - $250,000 grant
• Two (2) - $100,000 grant
• Eleven (11) - $50,000 grant

About Panorama GlobalPanorama Global is a social impact nonprofit that empowers changemakers through radical collaboration. We help our partners navigate the winding path from vision to impact. 

What We Do

• Collaboratives - Hosting and supporting collaborative efforts to achieve common goals.
• Fiscal Sponsorship - Financial and administrative support providing lean operating models to jumpstart projects.
• Funds - Philanthropic vehicles to manage and distribute funds that fuel global initiatives.

About  Innovative Postsecondary Models Fund

The Innovative Postsecondary Models (IPM) Fund supports innovative postsecondary education models that are rethinking how education is designed, delivered, financed, and assessed for learners in the United States.

The Fund is interested in innovations that benefit all learners, but especially learners whom the data show encounter the greatest obstacles to opportunity. The goal of this Fund is not only to provide funding to innovative models, but also to learn from selected grantees on how to reduce barriers to postsecondary access and increase student success outcomes to help inform the role philanthropy can play in supporting higher education innovation.

What We're Funding

We are seeking innovative postsecondary education models that demonstrate, or have the potential to demonstrate, meaningful improvements in how learners access, experience, and benefit from postsecondary education. We seek approaches with the potential to scale, influence the field, and inform how postsecondary education evolves nationally.

To help illustrate the types of innovations we hope to support, we have organized this opportunity around four broad themes. These themes reflect key dimensions of postsecondary innovation that have the potential to improve learner outcomes and inform broader systems change.

All four themes are grounded in a shared principle: student-centeredness. Truly innovative postsecondary models must be designed around learner needs, especially the needs of learners whom the data show face the greatest barriers to access and success in traditional postsecondary education.

Applicants are not expected to address all four themes, but should demonstrate strong alignment with at least one of the following:

Reimagining Instructional Design, Delivery, Assessment, and Student Support

• What success might look like:
  • Innovative instructional models improve student persistence, completion, and post-completion success, particularly for historically underserved learners, while maintaining or reducing costs.
  • Learners benefit from personalized, adaptive instruction and competency-based assessments that enable them to demonstrate and document skills in ways that are recognized by employers and other educational institutions.

Advancing Affordability and Financial Sustainability

• What success might look like:
  • Learners spend less overall, face reduced financial risk, and access high-quality education pathways that lead to credentials supporting economic mobility.
  • Successful models demonstrate affordability not only through reducing costs for learners, but also by maintaining or reducing the cost of delivering high-quality education through sustainable, efficient approaches.

Career and Workforce Alignment

• What success might look like:
  • Work and learning are more demonstrably connected and flexible, with evidence that skills are more directly tied to credentials and real career opportunities.

Removing Barriers for Underserved Learners

• What success might look like:
  • More learners from backgrounds and communities who the data show have faced the greatest barriers to accessing postsecondary education are able to access, complete, and benefit from high-quality credentials.

The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.

California Department of Health Care Access and Information

Mission: HCAI expands access to quality, equitable, affordable health care for all Californians by supporting high value delivery systems, resilient health facilities and workforces, and actionable health information and strategies.

HCAI is committed to expanding access to quality, equitable, affordable health care for all Californians by supporting high value delivery systems, resilient health facilities and workforces, and actionable health information and strategies.

California Rural Health Transformation (CalRHT) Program – California’s Implementation

The California Rural Health Transformation (CalRHT) program is California’s approach to the federal Rural Health Transformation Program (RHTP), led by the Department of Health Care Access and Information, with Centers for Medicare & Medicaid Services (CMS) oversight. CalRHT is designed to strengthen health care delivery in rural communities where access challenges, workforce shortages, and infrastructure gaps create unique barriers to care.

CalRHT Workforce Development Recruitment and Retention Program

Background and Mission

The Workforce Development Recruitment and Retention Program (WDRR), established under Initiative 2: Workforce Development of the California Rural Health Transformation (CalRHT) Program, aims to strengthen and sustain the rural healthcare workforce by improving recruitment, retention, and training for Health Professionals. WDRR funds eligible organizations to retain Health Professionals already practicing in rural communities and to recruit eligible Health Professionals to qualifying rural sites.

WDRR is an organizational grant program. HCAI awards grants to eligible rural-serving organizations who will provide bonuses to Health Professionals at their qualifying rural sites. Every bonus to Health Professionals carries a uniform five-year service obligation. 

Helen Frankenthaler Foundation Inc

The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.

Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.

Cultural Resilience Grant

The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:

• Climate Action and Sustainability
• Visual Arts & Education
• Cultural Resilience
  • Unrestricted support to sustain institutional capacity and core programming across the visual arts field. 
  • The Foundation provides unrestricted support to organizations whose core work is centered in the visual arts. These grants are intended to sustain exhibitions, programs, and institutional activities; support staffing, operations, and organizational capacity; and to maintain continuity during periods of reduced public funding and broader pressures affecting the arts and culture sector.
    • Cultural Resilience support is not project-based and does not require a defined initiative. 

The National Science Foundation (NSF) Directorate for Engineering (ENG) fosters groundbreaking research in electrical, communications, and computing systems through programs like Electronic, Photonic, Magnetic, and Quantum Devices (EPMQD) and Circuits and Systems for Communications and Sensing (CSCS). These initiatives emphasize innovative foundational research, particularly in power and energy systems, while being open to transformative ideas without immediate commercial outcomes. Funding availability will shape the portfolios of ECCS awards.

The MPS Mathematical Sciences Research Programs (MPS MathSci) by the NSF supports diverse research initiatives in theoretical and applied mathematical sciences. Key areas include Algebra, Applied Mathematics, Combinatorics, and Mathematical Biology. The program encourages groundbreaking foundational research with flexible budgets and durations. Proposals do not need to promise immediate outcomes, allowing researchers to explore innovative concepts without the pressure of commercial viability.

The NSF Core Research in Biological Sciences (BIO Core) program supports innovative research that enhances our understanding of biological systems, from molecular to biome scales. This funding opportunity encourages interdisciplinary proposals and can fund both single and multi-investigator projects. The awards will vary in scope and duration, accommodating exploratory projects and long-term commitments, depending on available funding and alignment with the program's objectives.

The FY 2026 funding opportunity aims to support Indian Tribes and intertribal consortia in implementing approved Nonpoint Source management programs under the Clean Water Act Section 319. This initiative, funded by the EPA, focuses on addressing NPS pollution through best management practices as outlined in Tribal NPS Management Program Plans, ensuring the protection of water resources and promoting sustainability in Tribal lands.

The MPS Physics Research Programs, funded by the National Science Foundation (NSF), support transformative research in various fields of physics. This includes experimental and theoretical work in atomic and molecular physics, particle physics, gravitational physics, and more. The NSF aims to promote ambitious projects without the need for immediate commercialization, focusing instead on foundational advancements that push the boundaries of our understanding of the universe.

The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.

The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.

The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.

The Emerging Frontiers in Research and Innovation (EFRI) program by the NSF aims to support transformative research in wave-based computing, fostering significant advancements in foundational engineering knowledge. With funding opportunities including EAGER awards and four-year grants up to $2 million, EFRI-WBC encourages interdisciplinary collaboration and innovative approaches to address strategic technology priorities. Proposals should articulate their potential long-term impacts on national science and technology missions, promoting a new era in computing methodologies.

The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The MPS Materials Research Programs, funded by the National Science Foundation, aim to enhance the understanding of materials and their diverse applications. These programs cover areas such as biomaterials, ceramics, condensed matter physics, and electronic materials. With an emphasis on transformative research, NSF MPS encourages proposals that are innovative and foundational, without the necessity for immediate commercial outcomes, fostering long-term advancements in materials science.

The ONR FY27 Young Investigator Program invites cutting-edge research proposals in priority areas that align with the interests of ONR Program Officers. This federal funding opportunity aims to support innovative projects led by early-career researchers, fostering advancements in science and technology relevant to the Navy. Interested applicants can find detailed eligibility criteria and contact information on the ONR website, encouraging collaboration and engagement in impactful research.

The Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD) aims to enhance the quality of birth defects and stillbirth surveillance in the U.S. By modernizing data collection through electronic case reporting, the initiative seeks to improve data quality and timeliness. The study will focus on identifying risk factors for birth defects and stillbirths, addressing a significant public health issue that affects thousands of pregnancies annually. CDC funding will support three key components in this effort.

The Preventing Violence Affecting Young Lives (PREVAYL 2.0) initiative aims to provide multiyear funding for state and local health departments to implement violence prevention strategies for adolescents and young adults. Key focuses include enhancing data-driven decision-making, building capacity for evidence-based strategies, integrating youth mental health support, fostering multisector collaborations, and prioritizing the prevention of various forms of violence, ensuring comprehensive support for youth development.

California Department of Health Care Access and Information

Mission: HCAI expands access to quality, equitable, affordable health care for all Californians by supporting high value delivery systems, resilient health facilities and workforces, and actionable health information and strategies.

HCAI is committed to expanding access to quality, equitable, affordable health care for all Californians by supporting high value delivery systems, resilient health facilities and workforces, and actionable health information and strategies.

California Rural Health Transformation (CalRHT) Program – California’s Implementation

The California Rural Health Transformation (CalRHT) program is California’s approach to the federal Rural Health Transformation Program (RHTP), led by the Department of Health Care Access and Information, with Centers for Medicare & Medicaid Services (CMS) oversight. CalRHT is designed to strengthen health care delivery in rural communities where access challenges, workforce shortages, and infrastructure gaps create unique barriers to care.

California Rural Healthcare Transformation (CalRHT) Initiative 1: Transformative Care Model Expand and Support Rural Workforce Capacity

The Family Medicine Obstetrics (FM-OB) Fellowship Subaward Program under Expand and Support Rural Workforce Capacity is intended to fund the programmatic and infrastructure costs of expanding FM-OB fellowship capacity. Primary applicants for the FM-OB Fellowship Subaward Program must be aspiring or existing graduate medical education (GME) sponsoring institutions. The Program expands access to high-quality maternity and perinatal care in California’s rural communities by increasing the number of family physicians with advanced obstetrics training. Through support for family medicine obstetrics fellowship programs and regional collaborative care models, the program builds sustainable obstetric workforce capacity where rural patients receive care, preparing physicians to practice in underserved communities and improving maternal and infant health outcomes.

PetSmart Charities

We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.

Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.

Adoption Growth Grants 

Purpose

Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.

Funding Support

Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:

• Staff positions supporting in-store adoption programs and events.
• Marketing and advertising for in-store adoption programs.
• Volunteer or foster support, incentives, and recruitment related to in-store adoption events.
• Event supplies, including containment and enrichment materials.
• Shelter software and technology needs.
• Vehicle repairs or transportation to adoption events.
• Innovative in-store adoption ideas and pilot programs.
• Other costs directly associated with facilitating PetSmart adoptions and in-store events.

There are two Cohorts under this funding: Cohort 1-  Accelerating in-store adoptions; and Cohort 2: Capacity Building.

Cohort 1- Accelerating in-store Adoptions

Applicants must have completed 500 or more adoptions in a PetSmart store in the U.S. within the last 12 months.

Preference will be given to organizations that demonstrate a clear plan to expand an existing in-store adoption program or introduce new in-store adoption models that will increase adoptions.

Four Required Steps

Applicants must complete all four required steps below before submitting a grant application:

• Step 1 - Watch the kick-off video and complete the Adoption Accessibility Questionnaire
• Step 2 - Confirm eligibility and connect with your Adoptions Grant Manager: After completing the questionnaire, you will receive an email confirming your eligibility. Eligible partners will be invited to a call with their Adoptions Grant Manager to discuss the grant opportunity, expectations, and potential fit.
• Step 3 - Engage your PetSmart store partners: Discuss your intent to apply, align on goals, and gain their commitment to support the success of your in-store adoption program.
• Step 4-  Submit your application.

The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.

The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.

About USA Track & Field Foundation Inc

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.Team and Club SupportThe USA Track & Field Foundation may be able to provide support to certain Elite Track & Field / Running clubs in the US.