Best Grants for Rare Diseases in Iowa

Nonprofit 501(c)(3) organizations in Iowa that support children, education, or health and human services can seek monetary program funding, which may include rare disease initiatives, from the Costco Foundation. Focused on measurable community impact and collaboration, applicants should demonstrate clear needs, evidence-based outcomes, and a broad base of financial support.

Nonprofit 501(c)(3) organizations with innovative human services or health-related programs in Iowa can seek support for new approaches to social problems. Creag Foundation supports creative solutions across areas like diseases and conditions, health care access, and community services; interested groups may submit a letter of inquiry for invitation-only funding consideration.

The DanPaul Foundation aims to enhance early childhood development by training teachers and parents, protecting children from abuse, and promoting social responsibility. They provide grants to non-profits for programs that focus on education, health, and welfare of youth. Key initiatives include scholarships, environmental education, and support for underprivileged children. Grant amounts range from a few hundred dollars to $15,000 annually, with a focus on impactful, community-driven projects.

Early-stage nonprofit and impact-first for-profit organizations tackling major social or environmental challenges in Iowa and beyond can access funding and intensive capacity-building support through Draper Richards Kaplan Foundation. Grants up to US $300,000 over three years back scalable, systems-focused solutions benefiting underserved communities, which may include innovative rare disease or respiratory health initiatives.

Nonprofit and NGO programs using technology for crisis response, education access, or economic empowerment in Iowa and worldwide can apply for Cisco Systems Foundation’s Global Impact Cash Grants, offering up to US $100,000 for innovative, early-stage solutions. Organizations serving mostly economically underserved communities, including those addressing rare or chronic disease impacts, may be eligible.

Educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies in Iowa can seek funding for safety, education, and community development initiatives. With a mission to strengthen communities, State Farm Companies Foundation provides support for projects like disaster preparedness, community revitalization, financial literacy, and K–12 or higher education programs that may benefit people with rare diseases.

Nonprofit cultural institutions in the U.S. can seek more than US $100,000 to support arts, science, and arts education programs through the William Randolph Hearst Foundation. Grants from William Randolph Hearst Foundation help Iowa organizations with performing arts, museums, STEAM education, and artist development that demonstrate broad impact and strong sustainability.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

Nonprofit and charitable-equivalent organizations working on health, education, or community programs in Iowa can apply for support that may include healthcare access, food pantries, STEM education, or wellness initiatives. Focused on community health and welfare, Labcorp Charitable Foundation invites projects that could benefit people affected by rare or chronic respiratory diseases.

Iowa organizations working on education, children’s health, or family economic stability for urban low-income youth can access funding through the Michael & Susan Dell Foundation for project support or scaling efforts. Eligible applicants include nonprofits, social enterprises, schools, governments, and other entities requesting more than US $50,000, with projects based in the U.S., India, or South Africa.

Accredited charities in Iowa and other countries can seek support for humanitarian, social development, science education, community, environmental, and contemporary arts projects that engage Roche expertise and employees. Grants from Roche help organizations whose programs may include rare or respiratory disease-related services, provided they are non-commercial and not tied to political, religious, or image-building purposes.

Nonprofit organizations providing health care, disease-related services, or humanitarian aid in Iowa can access funding through Semnani Family Foundation, which supports health, education, and disaster relief worldwide. Programs serving marginalized or vulnerable populations, including those affected by complex or rare conditions, may be eligible under its broad human welfare focus.

Iowa 501(c)(3) nonprofits working in health, medical research, education, or related charitable services can access funding through the Sidney Stern Memorial Trust for programs serving people in the U.S. Eligible projects should be well-managed, have broad impact on their target populations, and materially contribute to general welfare, including work connected to respiratory or rare diseases.

With a mission to strengthen communities, Bank of America Charitable Foundation provides Iowa nonprofits with sponsorship support for community development, basic needs, workforce education, and cultural programs. U.S. 501(c)(3) organizations, including those addressing health-related or rare disease impacts through housing, hunger relief, or inclusive community initiatives, may be eligible to apply.

Nonprofit 501(c)(3) organizations serving health, medical assistance, or humanitarian needs in the Southern U.S. can seek support for programmatic work from the Robinson Foundation. Focused on relieving hardship, it invites established charities (3+ years) addressing issues like poverty relief, disaster response, or family and youth services, which may include rare disease initiatives in Iowa’s southern communities.

Iowa 501(c)(3) nonprofits, public schools, and qualified local government entities can access funding for education, environment, entrepreneurship, and community enrichment projects that serve communities near Georgia-Pacific facilities. Georgia-Pacific Foundation prioritizes organizations within 30 miles of a GP manufacturing community whose programs strengthen long-term well-being and sustainability, which may include initiatives benefiting people with rare or respiratory diseases.

Nonprofit 501(c)(3) organizations in Iowa working on basic needs, youth education, workforce readiness, or domestic violence services can seek program support if located within 15 miles of a TJX site. With a mission to help vulnerable families and children build better futures, TJX Foundation provides invitation-only grants following an eligibility questionnaire and Letter of Inquiry process.

Nonprofit 501(c)(3) organizations, public schools, and libraries seeking support for environmental or human services programs in Iowa can apply for unrestricted grants ranging from US $5,000 - US $10,000. Lawrence Foundation funds general operating or project costs for U.S.-headquartered groups, which may include organizations addressing rare or respiratory diseases within its broad priorities.

The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.

Iowa 501(c)(3) nonprofits working on basic needs, community development, or volunteer-driven programs can access funding through Ameriprise Financial to support hunger relief, shelter, adult self-sufficiency, and cultural enrichment initiatives. Organizations must serve U.S. communities, show measurable outcomes and financial stability, and are strongest candidates when Ameriprise employees or advisors are actively engaged as volunteers.

Nonprofit 501(c)(3) organizations can seek project funding for education, health care, social services, environmental, civic, and cultural initiatives through the Dr Scholl Foundation, primarily serving U.S. communities including Iowa. Focused on broad community impact, this grant may benefit programs addressing rare or respiratory diseases within those eligible categories.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Nonprofit 501(c)(3) organizations in Iowa communities served by O’Reilly Auto Parts can seek funding for programs improving economic stability, workforce development, health and social services, and disaster relief. O'Reilly Automotive Foundation offers project, general operating, and capital support to U.S.-based charities benefiting underserved and underrepresented individuals and families.

Nonprofit 501(c)(3) organizations in Iowa can apply for Union Pacific Foundation’s Community Ties Local Grants, awarding US $5,000 - US $30,000 for safety, workforce development, community vitality, and environmental sustainability projects. Health and community organizations serving people with rare or respiratory diseases may be eligible if their programs fit these priority areas in Union Pacific–served communities.

Nonprofit 501(c)(3) organizations and equivalent charities with youth, family, food security, housing, or environmental programs can apply for the True Inspiration Awards in Iowa and beyond. With a mission to celebrate impactful community work, Chick Fil A Foundation provides grants of US $30,000 - US $350,000 to support and expand these initiatives, which may benefit rare disease populations indirectly.

Nonprofit organizations in Iowa with strong, replicable community partnerships addressing significant social issues can apply for national recognition and support through the Community Partnership Award. Mutual of America Foundation supports collaborative U.S. nonprofits; Iowa groups working on rare or respiratory diseases within broader community initiatives may be competitive.

Non-sectarian nonprofits helping disadvantaged people become self-reliant can receive US $5,000 - US $250,000 for human and social services, poverty alleviation, disability support, or disaster relief worldwide. Focused on smaller organizations, Gupta Family Foundation invites eligible 501(c)(3)s, including those serving Iowa communities through broader programs, to apply if they meet its mission and revenue criteria.