Upcoming Webinar
Instrumentl Fall Launch: Grant Work, Leveled Up.
Thu, Oct 29 or Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Lexington County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Lexington County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Richland County, Charleston County, and Greenville County.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

9,229 Results based on applied filters

Spirit of Sioux Falls Scholarship

Sioux Falls Area Community Foundation
Private
United States
Unspecified amount
The Spirit of Sioux Falls Scholarship supports college students pursuing business degrees while emphasizing community engagement and academic excellence. Eligible applicants must reside in Lincoln or Minnehaha County, South Dakota, and maintain full-time enrollment in appropriate programs. The scholarship aims to inspire philanthropy and improve local quality of life through educational advancement. Notably, previous recipients are ineligible for reapplication, ensuring fresh opportunities for new candidates. Multiple awards are available, promoting further education in the business field.
Education - Higher Education Business Education

Waneta Drake Miller Edmison Non-Traditional Student Scholarship

Sioux Falls Area Community Foundation
Private
United States
Unspecified amount
The Waneta Drake Miller Edmison Non-Traditional Student Scholarship is designed to support individuals aged 24 and older from Minnehaha, Lincoln, Turner, or McCook counties in South Dakota who are pursuing further education. Applicants must be enrolled in at least twelve credit hours at an accredited institution and have completed at least six credit hours in a degree program. This scholarship exemplifies the commitment to lifelong learning and community enrichment.
Education - Higher Education

Worden Christian Youth Ministry Scholarship

Sioux Falls Area Community Foundation
Private
United States
Unspecified amount
The Worden Christian Youth Ministry Scholarship supports full-time students entering their third or fourth year at an accredited four-year college or university, who plan to pursue a career in youth ministry. Candidates must demonstrate financial need and engage in school and community activities. Preference is given to those intending to serve as youth ministers in the Sioux Falls area, ensuring that the scholarship aligns with the mission of enriching local lives through philanthropy.
Education - Higher Education Religious / Theological Education

Good Neighbor Firefighter Safety Program Grant

National Volunteer Fire Council Inc
Private
United States
US $10,000
The Good Neighbor Firefighter Safety Program Grant, initiated by State Farm and the National Volunteer Fire Council, aims to support volunteer fire departments in acquiring critical safety equipment. In 2025, the program will award $1.5 million in grants, providing $10,000 each to 150 eligible departments. This initiative not only enhances firefighter safety and operational efficiency but also fosters community service, ensuring that these departments are well-equipped to respond effectively to emergencies.
Firefighting & Fire Prevention

Strategic Impact Grant

Bertin Family Foundation
Private
Countries
Unspecified amount
The Bertin Family Foundation Grants support 501(c)(3) public charities that align with the foundation's mission of community strengthening and compassion. Grant requests are accepted annually from July 1 to August 31, focusing on program or project support rather than general endowment. The foundation values measurable outcomes and responsible stewardship, and gives preference to organizations with Gold or Platinum status on Candid.
Disaster Relief / Humanitarian Aid Community Development & Revitalization Human & Social Services +3 more

The Research on Research Security Program

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Research on Research Security Program, funded by the National Science Foundation, aims to foster collaboration between STEM researchers and research security practitioners. It encourages interdisciplinary approaches to enhance evidence-based research on security issues. Proposals can include conferences, workshops, and planning grants, as well as international partnerships, to address U.S. concerns in research security. This initiative is vital for developing a robust community in this emerging field.
Science Engineering Domestic / Homeland Security +1 more

CareQuest Emergent & Relief Fund

Carequest Institute For Oral Health Inc
Private
American Samoa, Guam +4 more
Unspecified amount
The CareQuest Emergent & Relief Fund aims to address the unique challenges faced by historically underserved communities in the healthcare system, particularly in oral health. This fund supports innovative approaches, urgent clinical responses, and immediate relief efforts for community crises. Grants are targeted at organizations demonstrating commitment to equity in health services, ensuring that aid reaches those most in need. With a focus on transformative change, this initiative seeks to enhance access and improve health outcomes across diverse populations.
Disaster Relief / Humanitarian Aid Dental Health Minority Services

On My Way to Kindergarten Program

The Molina Foundation
Private
United States
Unspecified amount in in-kind support
The On My Way to Kindergarten Program offers essential resources to prepare children aged 3-5 for kindergarten. Developed with input from educators, it includes a bilingual activity book and online access to games, songs, and crafts in both Spanish and English. Funded by The Larry and Helen Hoag Foundation, this initiative aims to empower at-risk children and their families, ensuring they have the tools needed for a successful transition into school.
Education - Preschool / Early Learning Early Childhood Development

Book Buddies Program

The Molina Foundation
Private
United States
Unspecified amount in in-kind support
The Book Buddies Program, initiated by The Molina Foundation, aims to combat the lack of access to books in low-income communities. By distributing new, free books to eligible schools and agencies, the program fosters literacy and learning among children. With over 4 million books distributed, it helps create word-rich environments essential for educational success. This initiative supports families in building home libraries and enhances learning spaces, ensuring children have the resources they need to thrive.
Literacy Family Services Poverty Alleviation & Services +1 more

Maintenance Therapy in HER2+ Metastatic Breast Cancer (MBC) RFP

Pfizer, Inc.
Corporate
France, Germany +4 more
US $10,000 - US $250,000
This RFP invites proposals that explore the role of maintenance therapy in HER2+ metastatic breast cancer. It aims to enhance understanding of treatment optimization, emphasizing patient quality of life and individualized treatment strategies. Eligible applicants include organizations from the U.S. and select European countries. The focus is on educational projects that improve awareness among healthcare professionals, with a range of formats accepted, including live sessions and online content. Clinical research projects are excluded.
Endocrinology Breast Cancer

Michigan Sugar Company FFA Mini-Grant

Michigan Sugar Company
Corporate
United States
US $500 - US $3,000
The Michigan Sugar Company FFA Mini-Grant aims to support FFA chapters in advancing agricultural education within its growing region. Grants between $500 and $3,000 will be awarded to eligible institutions, focusing on establishing new chapters and enhancing educational resources. Applications are welcomed from any FFA chapter or school district committed to agricultural education. Preference will be given to proposals that include matching funds. This initiative reflects Michigan Sugar Company's dedication to community involvement and responsible growth.
Agricultural Education

Community Connect Grants

USDA: Rural Development (RD)
Federal Government
American Samoa, Guam +7 more
US $100,000 - US $5,000,000
The Community Connect Grants Program provides financial assistance to eligible applicants aiming to deliver broadband services in rural areas where access is limited. This initiative fosters economic growth and enhances educational, healthcare, and public safety benefits, improving the quality of life in underserved communities. By supporting projects that create better market opportunities and promote equitable access, the program plays a vital role in advancing rural development and addressing environmental justice.
Economic Services & Development Environmental Stewardship Climate Change Resilience & Equity +3 more

Dr. David Whiston Leadership Award

American Dental Association (ADA) Foundation
Association/Society
United States
US $5,000
The Dr. David Whiston Leadership Award, offered by the ADA Foundation, aims to support emerging leaders in oral health. This award grants $5,000 to individuals demonstrating commitment to enhancing access to dental education and employment opportunities. Eligible applicants include dental students, early-career dentists, and those under 40. Selection criteria focus on leadership potential and contributions to the profession, emphasizing community engagement and public health advancement. Visit ADAF.org for application details.
Dental Health Job Creation

Nourishing Neighbors Innovation Incubation Fund RFP

The Albertsons Companies Foundation
Corporate
United States
Up to US $300,000
The Nourishing Neighbors Innovation Incubation Fund RFP invites organizations to submit innovative proposals aimed at ending hunger. With flexible funding ranging from $50,000 to $300,000, this initiative encourages diverse ideas, whether small or large-scale. Organizations are required to have a panel of advisors with lived experience and must operate within the U.S. This grant focuses on creating sustainable solutions, ensuring communities can achieve self-sufficiency in food access.
Food Access & Hunger

I9 Sports Association

Utah Olympic Legacy Foundation
Association/Society
United States
Up to US $150
The I9 Sports Association provides scholarship grants to support youth sports participation for children under 18 in the U.S. Grants of up to $150 help offset registration fees for various recreational activities. With a focus on inclusivity and access, the association aims to foster athletic development and participation among young athletes. Applications are accepted year-round, with grants awarded in February, May, August, and November, ensuring ongoing support for youth sports engagement.
Recreation Sports & Athletics Youth Services

Incyte Healthcare - Independent Medical Education Grant

Incyte Corporation
Corporate
United States
Unspecified amount
Incyte Corporation offers an Independent Medical Education Grant to support innovative educational initiatives aimed at improving patient outcomes. This funding is available to organizations committed to delivering evidence-based education to healthcare professionals. Eligible activities may include live symposia, grand rounds, fellowships, and web-based programs. Organizations must enter into a written agreement with Incyte to receive funding. Note that new request submissions will be temporarily unavailable from November 21, 2025, to January 2026.
Medical Education & Professional Training

Housing Justice Program Fellowship

Equal Justice Works
Private
Maryland, South Carolina +1 more
Unspecified amount
The Housing Justice Program Fellowship, offered by Equal Justice Works, addresses the urgent need for legal assistance among low-income individuals facing housing instability in Virginia, South Carolina, and Maryland. This two-year fellowship provides legal and organizational training, networking opportunities, and essential support for fellows dedicated to combating eviction and promoting housing justice. Ideal candidates possess strong communication skills and a commitment to community advocacy, making a significant impact in the lives of those at risk of displacement.
Homeownership Equitable & Affordable Housing Economic Rights, Justice, & Mobility +1 more

Rural Summer Legal Corps (RSLC)

Equal Justice Works
Private
American Samoa, Guam +4 more
US $7,000
The Rural Summer Legal Corps (RSLC) addresses the legal service gap in rural U.S. communities by placing law students in civil legal aid organizations. This initiative, in partnership with Equal Justice Works and the Legal Services Corporation, allows 50 Student Fellows to engage in impactful projects, such as disaster response and housing issues, while gaining practical experience over eight to ten weeks. Participants receive a stipend of $7,000, enhancing their skills and supporting underserved populations.
Legal Services

Health Services Research Grants

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Health Services Research Grants, offered by the Foundation for Physical Therapy Research, focus on enhancing physical therapy services through evidence-based studies. Researchers are encouraged to explore areas such as therapy utilization, cost-effectiveness, and access barriers using rigorous methodologies. Proposals must align with the 2023 APTA Research Agenda, addressing topics that improve patient outcomes and care delivery, particularly in underserved populations. This initiative aims to elevate the role of physical therapists and optimize healthcare access.
Physical Therapy

Cardiovascular & Pulmonary Research Grants

Foundation for Physical Therapy Research
Private
United States
US $40,000
The Cardiovascular & Pulmonary Research Grants aim to support impactful research that enhances cardiovascular and pulmonary health through physical therapy interventions. This grant emphasizes studies that assess patient characteristics, improve health outcomes, and address disparities. Research proposals must align with the 2023 APTA Research Agenda and prioritize clinical relevance, employing various investigative designs. The goal is to foster innovative approaches that significantly reduce cardiovascular disease risks and improve patient care in the U.S.
Cardiovascular Diseases & Systems Chronic Obstructive Pulmonary Disease Physical Therapy

Regional Public Interest Awards

Equal Justice Works
Private
United States
US $250
The Regional Public Interest Awards recognize eight outstanding law students annually for their dedication to public interest law. Selected by the Equal Justice Works National Advisory Committee, each recipient demonstrates exceptional commitment through volunteer work, internships, and clinics. Awardees receive a $250 cash prize and a commemorative plaque, celebrating their significant contributions to their communities and the legal profession.
Legal Services

Water and Waste Facility Loans and Grants to Alleviate Health Risks on Tribal Lands

USDA: Rural Development (RD)
Federal Government
United States
Unspecified amount
The Water and Waste Facility Loans and Grants program aims to provide safe drinking water and waste disposal services to low-income communities on Tribal lands, addressing significant health risks. Eligible applicants include federally-recognized Tribes, state and local governments, and nonprofit organizations. Funding can be used for constructing essential water and waste systems, and while matching funds are typically required, a full grant is possible under certain conditions. Applications are accepted year-round.
Sanitation & Clean Drinking Water Waste Management Water Resource Management +3 more

Water and Waste Facility Loans and Grants to Alleviate Health Risks for Colonias

USDA: Rural Development (RD)
Federal Government
United States
Unspecified amount
The USDA Rural Development program provides essential loans and grants to improve water and waste disposal services in low-income communities, specifically targeting Colonias recognized before 1989. This initiative aims to alleviate health risks associated with inadequate access to safe drinking water and waste management. Eligible applicants include federally-recognized tribes and local governments, with funds supporting the construction of vital infrastructure to ensure community health and sustainability.
Sanitation & Clean Drinking Water Epidemiology & Public Health Waste Management +3 more

Frank D. Sylvia Trust Scholarship

Southcoast Community Foundation
Private
United States
Unspecified amount
The Frank D. Sylvia Trust Scholarship, established by the SouthCoast Community Foundation, honors Frank D. Sylvia's late son. This scholarship provides financial assistance to deserving high school seniors from Dighton or Somerset. Since its inception, the foundation has mobilized philanthropy, distributing over $50 million to meet community needs. The scholarship aims to support students with financial need, fostering educational opportunities and enhancing the quality of life in the region.
Career / College Preparation Academic Scholarship Programs

Postdoctoral Grant Program

University of Wisconsin - Madison
State/Local Government
United States, Wisconsin
Up to US $20,000
The Postdoctoral Grant Program at the University of Wisconsin School of Medicine and Public Health aims to support the growth and professional development of postdoctoral trainees, fellows, and associates. With funding up to $20,000 for one year, recipients can engage in independent research projects, attend workshops, or cover open-access publication fees. This initiative enhances research capacity and promotes health equity in Wisconsin, addressing critical health challenges while fostering career advancement in the medical field.
Cancer / Oncology Infectious & Parasitic Diseases Children’s Health & Pediatrics +6 more

NAILBA Charitable Foundation Grant

Nailba Charitable Foundation
Private
United States
Unspecified amount
The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.
Basic Human Needs Youth Services Poverty Alleviation & Services +7 more

Light the Way Equipment Grant Program

ETC
Corporate
United States
Unspecified amount
The ETC Equipment Grant supports U.S.-based non-profit organizations, schools, and government entities by providing essential lighting technology. This initiative, part of ETC's Light the Way Program, aims to enhance training in performance arts through equipment grants. Recipients can choose from a variety of packages, including consoles and LED fixtures, tailored to their facility's needs. ETC also offers training for all awarded equipment, ensuring recipients maximize the impact of their grants.
Performing Arts

Lexington County Grants for Nonprofits Highlights

Looking for Lexington County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Lexington County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Lexington County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Lexington County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Lexington County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081