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Best Madison County Grants for Nonprofits in Missouri

Looking for grants for 501(c)(3) nonprofit organizations working in Madison County, Missouri? Find the perfect grant for your nonprofit on Instrumentl.

34

Available grants

$443.6K

Total funding

$11.3K

Median grant

34 grants
$443.6K total
$11.3K median

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Last updated: October 5, 2026. Next update: November 1, 2026.

Unspecified amount

Nestle Purina Animal Welfare Grants

Rolling deadline
Nestlé Purina Animal Welfare Grants focus on enhancing the well-being of pets and their owners through monetary donations to 501(c)(3) tax-exempt pet welfare organizations in the U.S. These grants support capacity building, capital improvements, and spay/neuter funding. The program aims to strengthen relationships between pets and people, particularly in communities near Nestlé Purina facilities, ensuring that both pets and their owners thrive together.
Nestlé Purina

US $10,000

PLTW Engineering - Program Expansion (Ameren)

Applications due Mar 27, 2027

PLTW Engineering

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Engineering programs.

PLTW Engineering empowers students to step into the role of an engineer, adopt a problem-solving mindset, and make the leap from dreamers to doers. The program's courses engage students in compelling, real-world challenges that help them become better collaborators and thinkers. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Engineering programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Project Lead the Way inc.

Unspecified amount

Enhancing Pastoral and Social Ministry Grants

Rolling deadline
Catholic Extension's Enhancing Pastoral and Social Ministry Grants aim to empower the church to broaden its outreach and foster societal transformation through targeted pastoral and social initiatives. This program supports specific elements of the church's ministerial efforts, including funding for catechetical resources, marriage and family ministries, and social outreach for vulnerable populations. By investing in these areas, Catholic Extension seeks to enhance the church's role in communities, especially following disasters.
Catholic Extension

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Unspecified amount

Francis Grants

Rolling deadline
The Francis Grants, established by Catholic Extension, offer funding for significant events in poor mission dioceses, such as the ordination of new Bishops, anniversaries, or papal visits. These grants also support educational endeavors for Bishops. Named in honor of Francis Clement Kelly, Francis Cardinal George OMI, and Pope Francis, the program aims to strengthen the Catholic faith across the U.S. Since 1905, Catholic Extension has invested over $500 million to assist communities in need.
Catholic Extension

Up to US $3,000

Inclusion & Belonging Grant Program

Applications due May 6, 2027
The Inclusion & Belonging Grant Program by the Community Foundation of the Ozarks aims to promote diversity, equity, and inclusion in local communities. With $40,000 available, grants up to $3,000 support nonprofits, government entities, and schools in ensuring representation and engaging diverse voices in leadership. Applications are accepted anytime until funds are exhausted, fostering equitable opportunities for community involvement and event visibility in the Ozarks.
Community Foundation of the Ozarks Inc.

US $5,000

PLTW Launch - Program Expansion (Ameren)

Applications due Mar 27, 2027

PLTW Launch

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing and our expanding their PLTW Launch programs.

PLTW Launch's 43 interdisciplinary modules bring learning to life. The program empowers students to adopt a design-thinking mindset through compelling activities, projects, and problems that build upon each other and relate to the world around them. And as students engage in hands-on activities in computer science, engineering, and biomedical science, they become creative, collaborative problem solvers ready to take on any challenge.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Launch programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Project Lead the Way inc.

Up to US $50,000

Food Insecure Urban Agriculture Matching Grant Program

Applications due Aug 26, 2027
The Food Insecure Urban Agriculture Matching Grant Program aims to alleviate food insecurity in urban areas by funding projects that enhance food production and accessibility. Grants cover up to 75% of project costs, with a maximum of $50,000. Eligible applicants include individuals and organizations in designated urban areas of Missouri. The program supports initiatives like community gardens and farmers markets, fostering local economic growth and sustainable agricultural practices. This initiative is vital for improving food availability in underserved communities.
Missouri Department of Agriculture

US $30,000

PLTW Engineering - New Program (Ameren)

Applications due Mar 27, 2027

PLTW Engineering

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Engineering programs.

PLTW Engineering empowers students to step into the role of an engineer, adopt a problem-solving mindset, and make the leap from dreamers to doers. The program's courses engage students in compelling, real-world challenges that help them become better collaborators and thinkers. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Engineering programs beginning in the next academic year.

PLTW Program Status

New Program

Grant Award and Distribution Schedule

  • Total Award: $30,000
    • First Year: $15,000
    • Second Year: $15,000

Project Lead the Way inc.

Approximately US $500

Specialty Grants: Lennie Cloud Fund for the Hearing Impaired

Applications due May 15, 2027
The Lennie Cloud Fund for the Hearing Impaired, managed by the Community Foundation of the Ozarks, aims to improve the lives of hearing-impaired individuals in the Ozarks. This grant will provide $500 to nonprofit agencies that offer essential equipment, programming, or training. Eligible applicants include 501(c)3 organizations, government entities, school districts, and faith-based organizations. The fund emphasizes non-discrimination in its practices and supports community grantmaking across central and southern Missouri.
Community Foundation of the Ozarks Inc.

Unspecified amount

Charles L. and Dorothy Weaver Memorial Orthodontic Grant

Applications due Mar 31, 2027
The Charles L. and Dorothy Weaver Memorial Orthodontic Grant offers three scholarships annually for full orthodontic treatment to individuals aged 10 to 30 within the CFO Region. Applicants must demonstrate financial need, have a complete set of permanent teeth, and reside in the southern Missouri Ozarks. Successful candidates must also have reliable transportation to orthodontic appointments and access to ongoing dental care during their treatment. This initiative aims to enhance dental health and quality of life for eligible youth.
Community Foundation of the Ozarks Inc.

Up to US $25,000

Community Foundation of Ozarks: Welcoming Communities Grant

Applications due Sep 18, 2027
The Community Foundation of the Ozarks offers the Welcoming Communities Grant to promote inclusion and belonging in its service area. With $120,000 available and individual awards capped at $25,000, this program prioritizes agencies focused on creating a sense of belonging for underserved communities. Applicants should aim to raise awareness of access issues and improve civic participation, ultimately fostering long-term positive changes in community conditions for marginalized groups.
Community Foundation of the Ozarks Inc.

US $20,000

PLTW Gateway - New Program (Ameren)

Applications due Mar 27, 2027

PLTW Gateway

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing or expanding their PLTW Gateway programs.

Middle school is a time of exploration, a time when students are figuring out what they're passionate about today and how that relates to who they'll become tomorrow. During this transitional time, PLTW Gateway's 10 units empower students to lead their own discovery. The hands-on program boosts classroom engagement and excitement, drives collaboration, and inspires “aha! moments” and deep comprehension. And as students engage in PLTW's activities in computer science, engineering, and biomedical science, they see a range of paths and possibilities they can look forward to in high school and beyond.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Gateway programs beginning in the next academic year.

PLTW Program Status

New Program

Grant Award and Distribution Schedule

  • Total Award: $20,000
    • First Year: $10,000
    • Second Year: $10,000

Project Lead the Way inc.

US $15,000

PLTW Launch - New Program (Ameren)

Applications due Mar 27, 2027

PLTW Launch

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing and our expanding their PLTW Launch programs.

PLTW Launch's 43 interdisciplinary modules bring learning to life. The program empowers students to adopt a design-thinking mindset through compelling activities, projects, and problems that build upon each other and relate to the world around them. And as students engage in hands-on activities in computer science, engineering, and biomedical science, they become creative, collaborative problem solvers ready to take on any challenge.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Launch programs beginning in the next academic year.

PLTW Program Status

New Program

Grant Award and Distribution Schedule

  • Total Award: $15,000
    • First Year: $10,000
    • Second Year: $5,000

Project Lead the Way inc.

US $10,000

PLTW Computer Science - Program Expansion (Ameren)

Applications due Mar 27, 2027

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Project Lead the Way inc.

Unspecified amount

Explore the Ozarks Fund Grant

Rolling deadline
The Explore the Ozarks Fund Grant aims to enhance conservation education for K-12 students in the Ozarks by providing funding for various educational experiences. Eligible projects can include transportation for field trips, entry costs for students, and curriculum development. The grant requires a 1:1 match from the receiving organization, ensuring community involvement and support for these valuable educational initiatives.
Community Foundation of the Ozarks Inc.

Up to US $10,000

L-A-D Foundation Grant Program

Applications due Aug 27, 2027
The L-A-D Foundation Grant Program, established in 1962, is dedicated to conserving the natural and cultural resources of the Missouri Ozarks. Through partnerships and community support, the Foundation has awarded over $600,000 in grants to eligible 501(c)(3) organizations. Projects may focus on conservation education, community engagement, and innovative initiatives within a 12-county service area. The program encourages applications that align with its mission to enhance ecological and cultural sustainability.
Community Foundation of the Ozarks Inc.

US $50,000 - US $300,000

Delta Workforce Grant Program

Applications due May 15, 2027

Delta Workforce Grant Program

The Delta Workforce Grant Program (DWP) is an initiative designed to build long-term community capacity and increase economic competitiveness by providing grants to support workforce training and education programs throughout the lower Mississippi River Delta and Alabama Black Belt regions.

DWP supports projects and initiatives that create a more vibrant economic future for the Delta region by expanding opportunities to recruit, train, and retain a diverse and local workforce; aligning workforce and economic development strategies; creating sustainable talent pipelines; establishing or enhancing locally/regionally significant sector-based partnerships; and supporting enhanced workforce productivity through investments in innovative programming or services.

Delta Regional Authority

Up to US $10,000

Regional Everyone Outdoors Grant Program

Applications due Nov 13, 2026
The Regional Everyone Outdoors Grant Program, offered by the Community Foundation of the Ozarks, aims to enhance community engagement with the natural resources of the Ozarks. Nonprofit organizations, government entities, and schools in rural Missouri are invited to apply for funding to support innovative outdoor programming. Ideal projects focus on low-income neighborhoods and include environmental education, equipment purchase, and community gathering space enhancement. This grant does not require matching funds, promoting broader participation in outdoor activities.
Community Foundation of the Ozarks Inc.

Unspecified amount

Sparklight/Cable One Charitable Giving Fund

Applications due Oct 31, 2026
The Sparklight/Cable One Charitable Giving Fund supports local nonprofits and organizations focused on education, food insecurity, and community development. They prioritize impactful partnerships that strengthen communities. The fund welcomes various funding requests, including special projects and capital campaigns, while adhering to specific eligibility requirements such as tax-exempt status. However, they do not fund basic operating expenses, loans, or religious organizations for general support, ensuring that their contributions foster meaningful community growth.
Sparklight

US $20,000

PLTW Computer Science - New Program (Ameren)

Applications due Mar 27, 2027

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

New Program

Project Lead the Way inc.

US $2,500 - US $50,000

Spectrum Digital Education Grants

Applications due Feb 27, 2027
Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.
Charter Communications / Spectrum Mobile LLC

Unspecified amount

Nestle Purina Event Sponsorship

Rolling deadline
Nestlé Purina is dedicated to enhancing the well-being of pets and the communities they serve. Through their event sponsorship program, they support 501(c)(3) tax-exempt pet welfare organizations in the U.S. that focus on the welfare of cats and dogs. Eligible events must be located within 50 miles of their St. Louis headquarters, ensuring that their contributions directly benefit local communities. Purina's commitment to pets and people strengthens the bond between them.
Nestlé Purina

Unspecified amount

Engaging Young Catholics Grants

Rolling deadline
The Engaging Young Catholics Grants aim to support ministries that provide faith formation to children, teens, young adults, and families. By focusing on the pastoral needs of young Catholics, the program enhances community vibrancy and fosters new leadership within the church. Catholic Extension prioritizes operational support and seed funding for initiatives that develop youth and young adult ministries, ensuring that dioceses can effectively reach and engage younger generations in their faith.
Catholic Extension

US $15,000 - US $25,000

Coover Regional Resiliency Grant Program

Applications due Jan 15, 2027
The Coover Regional Resiliency Grant Program, a collaboration between the Community Foundation of the Ozarks and The Commerce Trust Company, aims to support nonprofit organizations and agencies serving low-income individuals facing financial challenges due to reduced federal or state funding. This program addresses critical social issues such as poverty and housing instability by providing funding for various projects, including organizational restructuring and capacity-building efforts, ensuring the long-term viability of these essential services.
Community Foundation of the Ozarks Inc.

Up to US $5,000

Holocaust Education Grantmaking Program

Applications due Jun 1, 2027
The Holocaust Education Grantmaking Program, facilitated by the Community Foundation of the Ozarks, supports educators and leaders in visiting the St. Louis Kaplan Feldman Holocaust Museum or the United States Holocaust Museum. The grant covers travel expenses, encouraging learning to educate others about the Holocaust and other genocides. Eligible applicants include IRS-approved organizations, ensuring no discrimination in awards. Applications are accepted until May 1, 2026, in various counties throughout Missouri.
Community Foundation of the Ozarks Inc.

US $10,000

PLTW Gateway - Program Expansion (Ameren)

Applications due Mar 27, 2027

PLTW Gateway

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing or expanding their PLTW Gateway programs.

Middle school is a time of exploration, a time when students are figuring out what they're passionate about today and how that relates to who they'll become tomorrow. During this transitional time, PLTW Gateway's 10 units empower students to lead their own discovery. The hands-on program boosts classroom engagement and excitement, drives collaboration, and inspires “aha! moments” and deep comprehension. And as students engage in PLTW's activities in computer science, engineering, and biomedical science, they see a range of paths and possibilities they can look forward to in high school and beyond.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Gateway programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Project Lead the Way inc.

Unspecified amount

Senior and Dorinda’s Dream Funds Grant Program

Rolling deadline
The Senior and Dorinda’s Dream Funds Grant Program provides financial assistance to fulfill end-of-life wishes for terminally ill adults in hospice care. Established by the Community Foundation of the Ozarks, it supports patients aged 18-65 through the Dorinda's Dream Fund, and those over 65 via the Senior Dream Fund. The grant covers costs like airline tickets for loved ones, with applications accepted anytime, ensuring that patients can make meaningful final connections.
Community Foundation of the Ozarks Inc.

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Madison County Grants for Nonprofits Highlights

Looking for Madison County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Madison County grants recommended for your specific programs in Missouri.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in Missouri

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in Madison County Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the Madison County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for Madison County Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

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