Best Orange County Grants for Nonprofits in Florida

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

Nebraska Library Commission Grants Schedule

Nebraska Library Commission Grants: The Nebraska Library Commission awards grants to Nebraska libraries and library organizations according to the following schedule. These grants are financed with funding made available through the Nebraska Unicameral Legislature or through the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act.

Continuing Education and Training Grants

This year, the Nebraska Library Commission is opening the CE grants to 1) online learning, 2) attending out-of-state conferences or workshops, and 3) larger continuing education projects.

The purpose of these continuing education grants is to assist Nebraska libraries in improving the library services provided to their communities through continuing education and training for their library personnel and supporters. Successful applications will show how the continuing education and/or training proposed will support the library's mission.

For this round of CE and training grants, applications should be for events happening before June 2026. (All reimbursement forms and receipts must be submitted by June 12, 2026.).

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.

The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.

The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.

The BRAIN Initiative seeks to develop innovative tools and approaches for neuroscience research, focusing on cell-specific and circuit-specific processes within the central nervous system. This initiative encourages projects that enhance our understanding of brain architecture and function through novel technologies for characterizing neural components and advancing methods for recording and modulating neural activity. Applications are invited to address significant challenges and promote transformative breakthroughs in neuroscience.

The National Institute of Mental Health is inviting research applications for the AIDS Research Center program, which includes Developmental Centers and full Research Centers. This initiative aims to enhance interdisciplinary HIV/AIDS research through collaboration and innovative approaches across various scientific domains. The program emphasizes alignment with national strategies and encourages applications from teams skilled in fostering partnerships with diverse stakeholders. Although applications are currently not being solicited, this notice allows potential applicants time to prepare strong proposals.

The National Institute of Allergy and Infectious Diseases (NIAID) is advancing research on immune tolerance through its Collaborative Network. This program aims to clarify the mechanisms of immune tolerance and develop interventions for related diseases, including transplant rejection and autoimmune disorders. Key objectives include conducting clinical trials on tolerogenic strategies and refining immune assays. This initiative is supported by regulations under the Public Health Service Act, ensuring a structured approach to improving patient outcomes.

The Clinical Data, Safety and Statistical Centers (CDSSC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance clinical research through comprehensive support. This includes statistical analysis, protocol development, and oversight of safety monitoring in studies related to asthma, autoimmune diseases, and transplantation. By coordinating these efforts, the program seeks to facilitate impactful research outcomes and improve public health outcomes through informed data-driven decisions.

The Translational Transplantation Tolerance Cooperative Study Group, supported by the National Institute of Allergy and Infectious Diseases, aims to advance transplant tolerance strategies that promote long-term graft survival without lifelong immunosuppression. This initiative focuses on developing, optimizing, and evaluating methods to induce immune tolerance in allogeneic transplants through collaborative efforts across multiple centers, utilizing translationally relevant models to ensure effective outcomes.

The NIAID aims to enhance our understanding of the interplay between chronic and infectious diseases through innovative precision systems biology research. By utilizing advanced technologies such as multi-omics and artificial intelligence, the initiative focuses on uncovering critical pathways that connect infections to chronic health issues. This multidisciplinary approach leverages longitudinal patient data to inform and improve prevention and treatment strategies, ultimately seeking to provide insights into disease progression and host-pathogen interactions.

The Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program, supported by the National Institute of Allergy and Infectious Diseases (NIAID), aims to enhance research on asthma and related allergic diseases. This initiative fosters multi-center, multidisciplinary research to explore disease mechanisms and treatment responses. By promoting clinical trials and observational studies, the AADCRC seeks to advance understanding and improve interventions for conditions such as asthma and food allergies, ultimately benefiting public health.

Florida Department of Transportation

The Florida Department of Transportation (FDOT) is an executive agency and directly reports to Governor Ron DeSantis. FDOT’s continuing mission is to provide a safe statewide transportation system that promotes the efficient movement of people and goods, supports the state’s economic competitiveness, prioritizes Florida’s environment and natural resources, and preserves the quality of life and connectedness of the state’s communities. This mission is accomplished through a primary purpose to plan and develop (either directly or indirectly) Florida’s robust transportation system. 

Highway Safety Grant Programs

The Florida Department of Transportation (FDOT) State Safety Office awards subgrants to traffic safety partners that undertake priority area programs and activities to improve traffic safety and eliminate crashes, serious injuries, and fatalities. Subgrants may be awarded for assisting in addressing traffic safety deficiencies, expansion of an ongoing activity, or development of a new program.

Subgrants are awarded as "seed" money to assist in the development and implementation of programs in traffic safety priority areas. Many types of organizations are eligible to receive traffic safety subgrant funding including government agencies, political subdivisions of state, local, city and county government agencies, law enforcement agencies, state colleges and state universities, school districts, fire departments, public emergency service providers, and certain qualified non-profit organizations (e.g., MADD, SADD, etc.).

Each applicant must develop a concept paper that identifies a traffic safety problem in the applicant’s jurisdiction. Applicants should provide documentation in the form of crash data of the traffic safety problem targeted by the subgrant. Concept papers must detail the activities of how the traffic safety problem will be addressed using subgrant funds.

Traffic Safety Priority Areas

The following are the priority areas that are available for subgrant funding: 1) Aging Road Users; 2) Community Traffic Safety Outreach; 3) Distracted Driving; 4) Drowsy Driving; 5) Impaired Driving; 6) Interstate Speeding Enforcement; 7) Motorcycle Safety; 8) Occupant Protection and Child Passenger Safety; 9) Pedestrian and Bicycle Safety; 10) Law Enforcement Liaison Program; 11) Public Traffic Safety Professionals Training; 12) Speed/Aggressive Driving; 13) Teen Driver Safety; 14) Traffic Records; 15) Traffic Records Coordinating Committee (TRCC); 16) Work Zone Safety.

Traffic Records Coordinating Committee (TRCC)

The National Highway Traffic Safety Administration (NHTSA) awards additional funding that can only be used for Traffic Records with the condition that the distribution of these funds must be made by a TRCC. The review and approval of these subgrants goes through a separate process but is otherwise similar to the above Traffic Records priority area.

The funding can be used for projects that improve the accuracy, completeness, timeliness, and uniformity of the state's six traffic records systems (citation/adjudication, crash, driver, EMS/injury surveillance system, roadway, and vehicle) or that advance the goals and objectives of Florida's TRCC as documented in the Florida Traffic Safety Information System Strategic Plan. TRCC subgrant funding to purchase third party software to provide an interface with law enforcement agencies to submit electronic citation data is not allowed. If the funding will be used to purchase a Records Management System, Case Management System, or other type of overall document management system, only the portion of the system related to traffic records (e-crash or e-citation data) can be funded. 

Agencies are encouraged to apply for both the Traffic Records and TRCC priority areas. Please note this requires the submission of two separate concept papers, which can be exactly the same. 

Florida Department of Transportation

The Florida Department of Transportation (FDOT) is an executive agency and directly reports to Governor Ron DeSantis. FDOT’s continuing mission is to provide a safe statewide transportation system that promotes the efficient movement of people and goods, supports the state’s economic competitiveness, prioritizes Florida’s environment and natural resources, and preserves the quality of life and connectedness of the state’s communities. This mission is accomplished through a primary purpose to plan and develop (either directly or indirectly) Florida’s robust transportation system. 

Highway Safety Grant Programs

The Florida Department of Transportation (FDOT) State Safety Office awards subgrants to traffic safety partners that undertake priority area programs and activities to improve traffic safety and eliminate crashes, serious injuries, and fatalities. Subgrants may be awarded for assisting in addressing traffic safety deficiencies, expansion of an ongoing activity, or development of a new program.

Subgrants are awarded as "seed" money to assist in the development and implementation of programs in traffic safety priority areas. Many types of organizations are eligible to receive traffic safety subgrant funding including government agencies, political subdivisions of state, local, city and county government agencies, law enforcement agencies, state colleges and state universities, school districts, fire departments, public emergency service providers, and certain qualified non-profit organizations (e.g., MADD, SADD, etc.).

Each applicant must develop a concept paper that identifies a traffic safety problem in the applicant’s jurisdiction. Applicants should provide documentation in the form of crash data of the traffic safety problem targeted by the subgrant. Concept papers must detail the activities of how the traffic safety problem will be addressed using subgrant funds.

Traffic Safety Priority Areas

The following are the priority areas that are available for subgrant funding: 1) Aging Road Users; 2) Community Traffic Safety Outreach; 3) Distracted Driving; 4) Drowsy Driving; 5) Impaired Driving; 6) Interstate Speeding Enforcement; 7) Motorcycle Safety; 8) Occupant Protection and Child Passenger Safety; 9) Pedestrian and Bicycle Safety; 10) Law Enforcement Liaison Program; 11) Public Traffic Safety Professionals Training; 12) Speed/Aggressive Driving; 13) Teen Driver Safety; 14) Traffic Records; 15) Traffic Records Coordinating Committee (TRCC); 16) Work Zone Safety.

Work Zone Safety

Includes traffic safety programs to increase work zone awareness, enforcement, and education. Concept papers can address areas such as specialized enforcement, education, and/or public information efforts. Items eligible for funding under this category may include, but are not limited to, overtime for enforcement in work zones, overtime for dispatchers (as needed for larger agencies), overtime for subgrant reimbursement and reporting, speed measurement devices, and portable speed message board signs. Subgrants for equipment only are not allowable

The DoW Rare Cancers Concept Award for FY26 promotes groundbreaking ideas in rare cancer research. This award encourages innovative applications that explore novel courses of investigation without requiring preliminary data. Unique to this program is the prohibition against mentioning the Principal Investigator or collaborators in the proposal materials, ensuring an unbiased review process. This funding opportunity aims to advance scientific discovery in the rare cancer domain.

The Tribal Broadband Connectivity Program (TBCP) aims to enhance broadband access and adoption on Tribal lands, supporting initiatives for remote learning, telework, and telehealth. Administered by NTIA, this program provides vital funding to eligible entities under the Consolidated Appropriations Act of 2021 and the Infrastructure Investment and Jobs Act of 2021. This funding is crucial for fostering digital inclusion and improving connectivity in underserved Tribal communities.

The Native Entities Grant Program, initiated by NTIA under the Digital Equity Act of 2021, aims to support Indian Tribes, Alaska Native entities, and Native Hawaiian organizations. This program streamlines funding through a unified application for two significant initiatives: the State Digital Equity Capacity Grant and the Digital Equity Competitive Grant. By focusing on reducing administrative burdens, it enhances access to digital resources and equity in underserved communities.

The DoW Bone Marrow Failure Idea Development Award supports innovative, high-impact research aimed at understanding and curing bone marrow failure diseases. This grant is available to both Established Investigators and Early-Career Investigators, with no preliminary data required for applications. Reviewers assess proposals based on specific criteria tailored to the investigator's career stage. The focus is on achieving interpretable results that contribute significantly to the field.

The DoW Bone Marrow Failure Investigator-Initiated Research Award supports innovative research aimed at advancing the understanding and treatment of bone marrow failure. This funding opportunity encourages applications for translational and clinical studies, requiring preliminary data to strengthen proposals. Unique features include the ability for a partnering Principal Investigator to contribute to the research, thereby fostering collaboration while maintaining a focus on significant advancements in patient care.

The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.

The FY26 Duchenne Muscular Dystrophy Research Program's Idea Development Award promotes innovative, high-risk research aimed at advancing treatment for Duchenne muscular dystrophy (DMD). It encourages projects with a strong scientific basis and feasibility, focusing on therapies that work across all ages, including infants and nonambulatory patients. Eligible applicants include experienced and transitioning investigators, fostering diverse expertise to enhance DMD research and improve patient outcomes.

The FY26 Duchenne Muscular Dystrophy Research Program's Clinical/Translational Research Award supports pivotal research aimed at translating innovative therapeutic strategies into clinical applications for Duchenne muscular dystrophy (DMD). Two funding levels cater to diverse project complexities, along with a Partnering PI Option promoting collaboration between early-career and established investigators. This initiative emphasizes the integration of preliminary data and encourages pilot trials to advance DMD therapies effectively.

The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.

The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.

The FY26 Bone Marrow Failure Research Program's Resource Development Award aims to create a multiomic atlas from human bone marrow failure samples. This resource will be open-access, providing essential data for researchers and clinicians to enhance their understanding of bone marrow failure diseases. A comprehensive Data Resource Sharing Plan is required to ensure timely availability of the developed resource, fostering collaboration within the scientific community.

The DoW Kidney Cancer Early-Career Scholar Award is a unique initiative by the Academy of Kidney Cancer Investigators, established in FY19. It aims to foster innovative kidney cancer research through a mentoring program that pairs early-career scholars with experienced mentors. This program not only enhances research capabilities but also builds a robust network of kidney cancer researchers. By supporting promising scholars, the initiative aspires to advance the field and improve treatment outcomes for kidney cancer patients.