Best Puerto Rico Grants for Nonprofits

The NIJ FY 2026 State and Local Collection and Reporting of Crime Data program invites proposals for research aimed at enhancing the accuracy of crime data collection and reporting. This funding opportunity seeks to identify common challenges and develop effective best practices to improve data quality across jurisdictions. Studies that analyze how agencies collect offense data to ensure alignment with actual events and strengthen data governance practices are particularly encouraged.

The Child Protection Compact Annual Program Statement invites proposals aimed at combating child trafficking through collaborative efforts between the United States and other countries. This initiative focuses on enhancing the capacity to prosecute traffickers, providing care for victims, and implementing preventive measures. Organizations interested in applying must align with the objectives of the CPC to ensure comprehensive support and effective intervention against all forms of child trafficking.

The TIP Office of the US Department of State invites applications for projects aimed at combating human trafficking, adhering to the Trafficking Victims Protection Act. This initiative prioritizes prosecuting traffickers, protecting victims, and preventing trafficking through strategies outlined in the National Security Strategy, executive orders, and the annual Trafficking in Persons Report, while aligning with America First Foreign Policy priorities.

The DoW Neurofibromatosis Research Academy – Leadership Award supports established neurofibromatosis investigators to lead a virtual research academy. Designed for early-career scholars, this award promotes mentorship and collaboration in neurofibromatosis research. The Academy Director and Deputy Director, both at the Associate Professor level, will oversee pilot research projects that engage scholars and their mentors, fostering a dynamic research environment. This initiative aims to enhance the future of neurofibromatosis research through innovative leadership and collaboration.

The FY26 Pancreatic Cancer Research Program (PCARP) Idea Development Award promotes innovative, high-risk research aimed at significant advancements for pancreatic cancer outcomes. This award supports projects with preliminary data, focusing on impactful discoveries. It features a Partnering Principal Investigator option, enhancing funding for collaborations between experienced mentors and early-career researchers. All applications must align with the FY26 PCARP Focus Areas, ensuring relevance and potential for transformative results in pancreatic cancer research.

The FY 2027 International Visitor Leadership Program (IVLP) invites proposals for cooperative agreements to support staff and overhead costs for National Program Agencies. This foundational exchange program enhances U.S. foreign policy by fostering relationships with global leaders. Eligible recipients should have foreign policy expertise and experience in professional exchanges, creating tailored visits that align with participants' interests and U.S. goals. This initiative continues a legacy of impactful international collaboration since 1940.

The High Priority HIV and Substance Use Research funding opportunity aims to support innovative research that addresses the intersection of HIV and substance use. Researchers are encouraged to submit proposals that include a detailed research plan and preliminary data, exploring new avenues for prevention, treatment, and potential cures for HIV among people who use drugs. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

The DOW Combat Readiness – Medical Research Program's FY26 Translational Research Award supports innovative research aimed at improving trauma care outcomes. This program emphasizes hypothesis-driven studies that can transition promising technologies into practical solutions for enhancing casualty survivability. Applicants must provide preliminary data and utilize validated animal models, with a focus on projects that meet a minimum technology readiness level of 4, ensuring a mature translational research effort.

The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.

The Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) aims to enhance asthma prevention and treatment in economically disadvantaged pediatric populations. Funded by the NIH, CAUSE supports multi-site clinical studies to identify innovative strategies and treatment targets for asthma. Utilizing systems biology, the network seeks to discover specific disease endotypes suitable for new therapeutic approaches, addressing the high burden of asthma in urban settings.

This project aims to enhance health outcomes for women living with HIV in the South by integrating HIV care with comprehensive women's health services through coordinated Clinic and Community Collaboratives. By funding organizations to implement targeted strategies such as culturally responsive services and learning collaboratives, the initiative seeks to improve access to essential health services, increase the number of women initiating rapid ART, and foster sustainable healthcare models that address the unique needs of this population.

LSC’s Basic Field Grants aim to enhance access to civil legal services for low-income individuals across the U.S. and territories. These grants support eligible organizations for up to three years through a competitive application process. The funding is allocated to specific service areas, which change annually, and focuses on providing comprehensive legal assistance. The program includes three types of service areas, ensuring diverse populations, including agricultural and Native American communities, receive necessary legal support.

The National Cancer Institute (NCI) plans to issue a Notice of Funding Opportunity (NOFO) for the Paul Calabresi Career Development Award in Clinical Oncology (K12). This program aims to enhance training for clinician-scientists in cancer research, fostering their career development and collaboration with basic research scientists. It mandates diverse oncology specialties in faculty, individualized career development plans, and mentorship, supporting Scholars for up to three years to promote their research initiatives in clinical trials.

The NHLBI is set to release a NOFO aimed at enhancing an international research platform for cardiac surgery. This initiative will integrate various research areas, including mechanistic science and implementation science, to advance innovative techniques and improve health outcomes for adults with cardiovascular disease. Furthermore, the platform will serve to train future clinical trialists. Potential applicants are encouraged to start forming collaborations and preparing their proposals, as applications are not yet being solicited.

Lindsay Lloyd North Korea Freedom Scholarship

The Lindsay Lloyd North Korea Freedom Scholarship (supported by the George W. Bush Foundation) provides one or more annual scholarships for up to $10,000 to lawful permanent residents of the United States, U.S. citizens or refugees who were born in North Korea pursuing an educational program in the United States or its possessions. North Korean-born individuals pursuing a degree in accredited colleges and universities in the United States with South Korean citizenship are eligible to apply.

This scholarship may be renewed on an annual basis by completing the scholarship application in full. Renewal applications will be reviewed alongside first-time applicants.

The Maximizing Investigators' Research Award (MIRA) program, established by NIGMS, aims to enhance research funding efficiency by providing stable financial support to investigators. This allows for greater scientific flexibility and encourages innovative studies. MIRA is pivotal for distributing funding among promising researchers, fostering groundbreaking research. The program invites applications from eligible NIGMS-funded and NIH-defined New Investigators, as well as current MIRA grantees seeking renewal, ensuring a broad and inclusive approach to advancing science.

The National Institutes of Health is launching a funding opportunity to explore the mechanisms of skin injuries caused by toxic chemicals. This initiative aims to understand the common pathways of injury from various harmful substances, facilitating the discovery of therapeutic targets. Researchers are encouraged to collaborate and apply their expertise in cutaneous wound healing. The goal is to develop broad-spectrum medical countermeasures for mass casualty events involving toxic exposures, enhancing public health safety.

The Health Policy Research Scholars program, funded by the Robert Wood Johnson Foundation, aims to develop leadership among doctoral students from diverse, nonclinical disciplines. This four-year initiative focuses on aligning research with community health needs, emphasizing equity and collaboration across sectors. Scholars will receive $30,000 annually for up to four years, complemented by mentorship and training. The program targets second-year doctoral students who are committed to influencing health policy and fostering a Culture of Health in their communities.

The Advancing Equity Through Oral Health Funds, initiated by CareQuest Institute, seeks to transform oral health systems by supporting projects that dismantle disparities faced by marginalized communities. The program encourages organizations to propose innovative solutions that enhance access to dental care, engage community voices, and promote policies that ensure equitable health outcomes for all. This initiative aims to create a more integrated and accessible healthcare system, particularly for historically underserved populations.

The Pediatric Disaster Care Centers of Excellence Program aims to enhance the nation's readiness for pediatric care during disasters. It focuses on developing coordinated care capabilities, strengthening preparedness plans, and increasing statewide medical surge capacity for children. By funding four Centers of Excellence, the initiative seeks to improve healthcare professionals' competency through standardized training and enhance situational awareness regarding pediatric disaster care. This program addresses critical gaps in pediatric disaster management to ensure effective responses during high-consequence emergencies.

The Fiscal Year 2027 Regional Nutrition Hubs initiative by the US HHS aims to enhance nutrition services across regional health centers. By providing targeted technical assistance, the program seeks to improve health outcomes through effective nutritional interventions. This initiative supports HRSA's mission to expand access to high-quality healthcare services, ultimately benefiting communities by addressing dietary needs and managing health conditions. With a focus on collaboration, the program is set to strengthen the health infrastructure at the local level.

The Core State Injury Prevention Program (Core SIPP) aims to enhance public health infrastructure and partnerships to prevent unintentional injuries through data-driven strategies. Focusing on key areas such as traumatic brain injury, falls among older adults, and drowning, it seeks to improve community safety by strengthening data use and fostering collaborations. This initiative supports states in identifying local injury concerns, thus promoting evidence-based prevention approaches and increasing the capacity for sustained public health actions.

The NIH's Investigator-Focused Award (Parent R35) aims to support research programs for investigators at all career stages, including Early Stage Investigators. This funding provides stability and freedom in research, allowing for innovative and ambitious studies without the constant pressure of securing new grants. Key benefits include flexibility in research direction, opportunities to tackle significant questions, and a greater potential for scientific breakthroughs, fostering a robust research environment.

The Transition to Aging Research Award for Predoctoral Students, funded by the National Institute on Aging (NIA), invites exceptional graduate students to pursue aging-related postdoctoral training. This two-phase award supports late-stage doctoral candidates in completing dissertation projects across diverse research areas. It aims to facilitate smooth transitions into competitive aging-focused postdoctoral roles, fostering the development of future investigators in aging research. This initiative is designed to enhance collaboration and impactful research in the field of aging.

The National Institutes of Health (NIH) is inviting applications for the Multidisciplinary Research to Accelerate Hepatitis B Cure in Persons Living with HIV and HBV (MRA-HBV) program. This initiative aims to enhance understanding of hepatitis B persistence and pathogenesis, identify biomarkers, validate drug targets, and create non-invasive diagnostics. It supports observational cohorts paired with multidisciplinary teams utilizing existing clinical data, contributing to innovative research in hepatitis B cure strategies.

The NIGMS Institutional Biomedical Undergraduate Research Training Program aims to enhance the training of undergraduate students in biomedical research. By supporting institutions with limited NIH funding, the program provides trainees with 2–3 years of full-time research training. This initiative fosters a skilled workforce prepared for advanced biomedical degrees, addressing national health-related research needs through comprehensive educational and developmental programs.

• Innovative: An approach that brings fresh thinking, tools, or models to homeownership in ways that challenge the status quo and demonstrate a disruptive, future-oriented vision with potential to inspire or shift broader field practice.
• Impactful: A solution with meaningful potential to expand homeownership through knowledge and action, featuring clear and measurable progress indicators that demonstrate capacity to shift trajectories for low- and moderate-income households.
• Bridge-Building: An initiative that effectively connects and unifies a wide range of stakeholders, fostering meaningful collaboration across sectors or perspectives. The strongest submissions will reflect strong community partnerships across the housing ecosystem.
• Durable: A sustainable pathway that addresses root causes of homeownership barriers rather than just symptoms, with compelling evidence of potential to elicit robust support from broad private, philanthropic, and public funding sources over time.