Best Large Grants for Nonprofit Organizations in Illinois

The Community Possible Grant Program by U.S. Bank aims to foster economic and workforce advancement, as well as safe and affordable housing. By partnering with 501(c)(3) nonprofit organizations, the program seeks to drive lasting change within communities through collaborative grantmaking. Priority is given to organizations that promote diversity, equity, and inclusion, and that address multiple pillars of work, home, and play. This initiative reflects U.S. Bank's commitment to creating a more equitable society.

Who We Are & What We Do

On November 26, 1997, a small group of citizens with an abundance of enthusiasm embarked on a mission to secure the quality of life in our region now and forever. By yearend, they had a modest $1,050. Through commitment and vision, the Quincy Area Community Foundation expanded and grew to become the Community Foundation Serving West Central Illinois & Northeast Missouri. 

Serving 12 counties on both sides of the Mississippi River, we operate as a bridge between our donors’ charitable visions and the nonprofit organizations that bring those visions to life. 

Communityworks Endowment Fund

Communities in Illinois, Missouri, and across the country face challenges in early childhood education, workforce development, and land use and protection. However, many lack the resources to address and advance them. In 2003, the Grand Victoria Foundation (GVF) launched the Communityworks initiative to strengthen Illinois Community Foundations’ ability to do so.

After securing three rounds of support from GVF and leading a two-year effort to identify challenges and opportunities in these three target areas, your Community Foundation established its Communityworks Endowment Fund, which is open to 501(c)(3) organizations or units of government that advances workforce development, childcare, and early childhood education in Adams, Brown, Hancock, and Pike Counties, IL.

Meanwhile, the Community Foundation continues to evaluate changing needs and opportunities in these critical focus areas in order to make strategic, meaningful grants.

CommunityWorks Fund Priorities

ISSUE AREA 1

Early Childhood Education Long-Term Vision:

• To have a large pool of educated providers who see themselves as professionals who take advantage of the ongoing opportunities to grow in their field.
• To educate parents on the benefits and value of choosing quality child care.
• Increase revenue streams for child care providers over and above parent fees and raise value / respect for child care profession.

Early Childhood Education Short-term Vision:

• Improve the quality and quantity of the region’s child care settings.

Goals:

• Encourage providers to maintain and improve the quality of their child care programs.
• Increase community awareness of child care's impact on our communities.
• Strengthen the relationship and involvement between parents, providers, and employers.
• Improve provider retention in the child care field.

ISSUE AREA 2

Workforce Development Long-Term Vision:

• Ensure current and future workers are prepared with the skills needed to fill a variety of existing, expanding, and new employment opportunities that provide livable wages and benefits to ensure workforce sustainability.

Workforce Development Short-term Vision:

• Improve essential and technical skills in the region.

Goals:

• Identify high-priority workforce needs and individuals to help fill them.
• Increase access to and participation in skills training to fulfill high-priority workforce needs.
• Reduce barriers for individuals to enter the workforce.
• Provide supports for individuals to successfully remain in the workforce.

The Costco Wholesale Charitable Contributions program prioritizes support for children, education, and health services within local communities. Nonprofit organizations seeking assistance must be 501(c)(3) certified and focus on monetary requests. Applications are reviewed within 4-6 weeks, factoring in community needs and collaboration. However, Costco limits grants to 10% of the program budget and typically restricts organizations to one request per fiscal year. They do not fund individuals or direct aid for various specific purposes.

CSX Charitable Investments provide essential in-kind donations to nonprofit organizations focused on supporting military members and community first responders. Through intermodal transportation services, CSX offers equipment and rail services to help reduce transportation costs for eligible organizations. The program also includes occasional donations of railroad materials and equipment based on availability. CSX prioritizes support for organizations operating within its service areas, promoting community betterment and development.

The Draper Richards Kaplan Foundation provides grants to early-stage social entrepreneurs working on scalable solutions to pressing social and environmental issues. By supporting organizations with innovative approaches and proven impact, they aim to uplift underserved communities globally. The foundation offers operational support, funding of up to $300,000 over three years, and fosters a collaborative community among its portfolio organizations. They focus on candidates demonstrating measurable impact and sustainable growth potential.

The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

The Stantec Community Engagement Grant is dedicated to enhancing the quality of life in communities where Stantec operates. Focused on arts, education, environment, and health and wellness, the grant supports initiatives that foster sustainable development and responsible practices. Organizations seeking funding must align with Stantec's values, emphasizing ethical practices and community impact. Preference is given to projects located near Stantec offices, ensuring a more significant local impact through their contributions.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Kroger Foundation is dedicated to uplifting communities through significant charitable contributions, having donated over $1.9 billion in the past six years. Their focus on combating hunger through the Zero Hunger | Zero Waste initiative exemplifies their commitment to social impact. Annually, they provide over $300 million to nonprofit organizations aligned with their mission, promoting health, education, and disaster relief while fostering diversity and inclusion. This initiative reflects Kroger's belief that strong communities are a shared responsibility.

The Access To Recreation Endowment Fund Grant, managed by the Community Foundation for the Land of Lincoln, supports nonprofit organizations in Sangamon County that provide accessible recreation programs for individuals with disabilities. This initiative, initially funded by the W.K. Kellogg Foundation, aims to enhance participation in adaptive sports and activities, ensuring that everyone has the opportunity to engage in both indoor and outdoor recreation without barriers.

The Retirement Research Foundation (RRF) offers Direct Service Grants to nonprofit organizations focused on enhancing the quality of life for older adults. These grants prioritize projects addressing caregiving, economic security, housing, and social connectedness. Organizations must demonstrate a clear understanding of the aging network and articulate service gaps. RRF emphasizes equity and supports initiatives that foster diversity, equity, and inclusion, particularly for historically marginalized populations. Applications are accepted from eligible nonprofit entities, aiming for transformative impacts in communities.

The Retirement Research Foundation (RRF) offers Professional Education & Training Grants aimed at enhancing the skills of professionals serving older adults (60+). The foundation focuses on projects with significant national or regional impact, particularly those addressing the needs of historically marginalized groups, including people of color and LGBTQ individuals. RRF seeks to foster a well-trained workforce capable of meeting the increasing demands of an aging population, thereby improving the quality of life for older Americans.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

The J.W. Couch Foundation Grant focuses on supporting Wildlife Conservation nonprofit organizations that align with their mission of community betterment and environmental protection. The foundation seeks partnerships with organizations that promote animal wellbeing, early childhood education, teacher support, and outdoor activities. Eligible applicants must be registered 501(c)3 nonprofits or for-profit entities aligned with their charitable programs. This grant emphasizes collaboration and community engagement to create lasting impacts.

Insperity's Corporate Contributions program emphasizes community involvement and corporate citizenship, providing philanthropic grants and event sponsorships to 501(c)(3) nonprofit organizations. Eligible organizations must engage Insperity employees or contribute to the communities where they operate. The program aims to support nonprofits in achieving their service goals and enhancing community welfare. Applications must be submitted 90 days prior to events, and funding requests can be made once a year.

The Dudley T. Dougherty Foundation Grant supports nonprofit charitable organizations recognized under section 501(c)(3) of the IRS Revenue Code. Established in 2002, the foundation aims to empower groups committed to positive change, fostering respect for life and the environment. Their vision emphasizes collaboration for a better future, encouraging applicants to embody these values in their initiatives. With a focus on impactful projects, this grant is an opportunity for organizations striving to make a critical difference in our world.

The TJX Foundation Grants support nonprofit organizations located within 15 miles of a TJX store that align with their community mission. Eligible areas include basic needs, education for at-risk youth, workforce training, and safety from domestic violence. Organizations must be a registered 501(c)(3) for at least 12 months and have a nondiscrimination policy. Applications are invited through a Letter of Inquiry, with funding decisions based on community impact.

The Green Infrastructure Grant (IL) offers funding for projects aimed at reducing stormwater runoff and mitigating flooding in Illinois. Administered by the Illinois EPA, this grant supports best management practices (BMPs) that enhance natural water management systems. With grants ranging from $75,000 to $2.5 million, eligible applicants include individuals, nonprofits, and government entities. Projects focused on environmental justice areas may receive up to 85% funding, promoting sustainable practices statewide.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.