Best San Francisco Grants for Nonprofits in California

The MPS Astronomical Sciences Research Programs, funded by the National Science Foundation, support innovative research in astronomical sciences. These initiatives aim to enhance our understanding of the universe through core research, technological advancements, and instrumentation. Topics include solar storm prediction, the discovery of exoplanets, and the study of black holes. Proposals should reflect ambitious, transformative ideas that may not require immediate practical outcomes, fostering long-term scientific exploration.

The NSF Expeditions in Computing program aims to foster transformative research in computer and information science. By funding projects up to $15 million over seven years, it encourages multidisciplinary teams to tackle ambitious research agendas that redefine the future of computing. The program supports innovative areas such as new architectures for intelligence, advanced robotics, and next-generation communication, emphasizing the importance of collaboration across various fields to achieve groundbreaking advancements.

The Emerging Frontiers in Research and Innovation (EFRI) program by the NSF aims to support transformative research in wave-based computing, fostering significant advancements in foundational engineering knowledge. With funding opportunities including EAGER awards and four-year grants up to $2 million, EFRI-WBC encourages interdisciplinary collaboration and innovative approaches to address strategic technology priorities. Proposals should articulate their potential long-term impacts on national science and technology missions, promoting a new era in computing methodologies.

The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The MPS Materials Research Programs, funded by the National Science Foundation, aim to enhance the understanding of materials and their diverse applications. These programs cover areas such as biomaterials, ceramics, condensed matter physics, and electronic materials. With an emphasis on transformative research, NSF MPS encourages proposals that are innovative and foundational, without the necessity for immediate commercial outcomes, fostering long-term advancements in materials science.

The FY26 Breast Cancer Research Program's Clinical Research Extension Award aims to enhance breast cancer clinical studies by extending data collection and follow-up. This funding mechanism emphasizes the importance of patient participation and addresses challenges from early trial terminations. Notably, applications must include two breast cancer consumer advocates and can feature either a single Principal Investigator or a duo. This initiative seeks to improve outcomes through comprehensive data analysis and patient engagement.

The FY26 Breast Cancer Research Program's Breakthrough Award supports transformative research aimed at significant advancements in breast cancer treatment. This award offers various funding levels, including Population Science Studies, allowing for innovative approaches that can lead to clinical applications. Each application must align with overarching BCRP challenges, ensuring a focus on impactful research. The program acknowledges both individual and collaborative Principal Investigators, emphasizing the importance of timely submissions to avoid administrative issues.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is set to renew a Notice of Funding Opportunity (NOFO) focused on advancing translational research in maternal and pediatric pharmacology. This initiative aims to enhance precision medicine by developing innovative tools and therapeutics for pregnant and lactating women, infants, and children. The goal is to improve the safety and efficacy of medications while ensuring effective patient-provider communications. Applications are not currently being solicited.

The Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC) program is designed to enhance research on muscular dystrophy through a collaborative, center-based approach. By fostering interdisciplinary projects and providing essential training for emerging scientists, the MDSRCs aim to drive innovation in both basic and clinical research. Engaging patient and advocacy communities is a key component, ensuring research is patient-centered and informed by real-world needs. This initiative is supported by various legislative authorities.

The National Institutes of Health is funding a groundbreaking project to enhance our understanding of Type 1 diabetes (T1D) through multimodal AI. This initiative aims to integrate diverse datasets to explore the interactions of biological processes in T1D development. By leveraging advanced AI models, the research will uncover critical insights, identify biomarkers, and pave the way for personalized medicine approaches, ultimately improving prevention and treatment strategies for this complex disease.

The SCORCH Program: Phase 2 aims to enhance the understanding of single cell biology in the context of HIV and Substance Use Disorder (SUD). Building on previous research, this initiative will explore new single cell approaches to investigate the interactions between SUD and HIV progression at various biological levels. By leveraging advanced techniques, the program seeks to identify candidate mechanisms and potential therapeutic targets, ultimately contributing to innovative solutions for SUDs and HIV-related challenges.

The National Violent Death Reporting System (NVDRS) is a crucial surveillance initiative by the CDC aimed at understanding violent deaths and suicides. This funding opportunity supports state and local entities in modernizing NVDRS, enhancing data collection and reporting processes. Key activities include timely data updates, modernization assessments, and pilot projects for improved data systems. The goal is to create a sustainable national surveillance system that provides reliable data to inform public health actions and enhance violence and suicide prevention efforts.

About USA Track & Field Foundation Inc

The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.

Mission: 

To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.Team and Club SupportThe USA Track & Field Foundation may be able to provide support to certain Elite Track & Field / Running clubs in the US.

About She+ Foundation The SHE+ Foundation, formerly known as The Patty Brisben Foundation for Women’s Sexual Health, was founded by Patty Brisben in 2005 after she recognized the profound need for a movement to address the too often ignored aspects of women’s sexual health. The SHE+ Foundation is committed to changing the narrative. We are here to advocate, educate, and fund research that advances the understanding and treatment for women’s sexual health, and improves quality of life for all women.Mission: Our mission is to advance women's sexual health and well-being through groundbreaking research, comprehensive education, and unwavering support. We strive to eradicate stigma, empower women with knowledge, and ensure equitable access to quality healthcare for all, regardless of socioeconomic status, race, or geography.About She+ Foundation GrantWe fund a wide range of projects that align with our mission to advance women's sexual health. This includes:

• Research Studies: Clinical and academic research aimed at understanding and improving women's sexual health.
• Educational Programs: Initiatives that provide education and awareness on topics related to women's sexual health.
• Community Outreach: Programs that engage and support local communities, offering resources and support for women's sexual health.
• Innovative Treatments: Development and implementation of new treatments and therapies for women's sexual health issues.

The NSF Geosciences Core Research program funds innovative projects across atmospheric, geospace, earth, and ocean sciences. It encourages proposals that push the boundaries of knowledge in fundamental research, promoting interdisciplinary approaches. This initiative seeks transformative ideas that may not have immediate commercial applications but are crucial for advancing scientific understanding and addressing complex environmental challenges. Researchers are invited to explore various domains or integrate multiple disciplines to enhance our comprehension of the Earth and its systems.

The Rural Communities Opioid Response Program - Overdose Response aims to enhance healthcare access in rural areas by addressing urgent needs related to substance use disorder services. This initiative focuses on reducing overdose risks through targeted interventions and support, ensuring that rural communities receive necessary assistance. Funded by the Health Resources and Services Administration, this program is crucial for mitigating the opioid crisis in underserved regions, improving health outcomes, and promoting overall community well-being.

The Rural Communities Opioid Response Program focuses on enhancing behavioral health care services for children and adolescents in rural areas. By providing essential funding, this initiative aims to tackle mental health and substance use disorders, ensuring that young individuals receive the support they need. The program, administered by the Health Resources and Services Administration, is crucial in addressing the unique challenges faced by rural communities, promoting healthier outcomes for future generations.

Wallingford Education Foundation

Our Mission

The Wallingford Education Foundation is a non-profit, community-based partnership supporting educational innovation and excellence in our town.

Our Vision

The Wallingford Education Foundation empowers ideas and enhances educational experiences for students, educators and community members. It provides financial support outside the education budget that is aligned with the goals and focus areas of the school district’s strategic plan.

Professional Development Grant

Transformative impacts often result from staff members who choose to attend professional development programs. Typically, these opportunities are funded through the town’s annual school budget. However, the district may not be financially able to meet each request. Through the Professional Development Grant program, the Wallingford Education Foundation (WEF) provides additional funding for employees of Wallingford Public Schools to attend conferences hosted outside the district.

The Professional Grant program offers paired grants of $1,000 each for two Wallingford Public Schools staff members to attend the same professional development opportunity together OR single grants of up to $2,000 for an individual to attend a conference alone. Multiple grants are awarded yearly.

About Spirit of Blue

Our Vision

To become the nation’s leading supplemental provider of law enforcement safety equipment and training across the county.

Our Mission

Spirit of Blue is dedicated to the enhancement of officer safety throughout the law enforcement community by fulfilling unfunded safety equipment and training needs.

Safety Grant Program

Spirit of Blue’s primary initiative is the granting of safety equipment and training to municipal, county and state law enforcement agencies in an effort to protect their sworn personnel. 

Most grants are 100% funded, meaning that no match is required. In the majority of cases, Spirit of Blue conducts the procurement of the goods or services being granted so that the recipient agency isn’t burdened with having to negotiate prices, place orders or track delivery. Rarely, if ever, does Spirit of Blue provide cash awards. Once selected, Spirit of Blue will provide the recipient agency with an official grant award letter outlining everything that is contained in the award. The recipient agency must gain acceptance of the grant, whether on the authority of their agency head or by working with their local governing authority as their policy may dictate. There are no reporting requirements after the award of the grant, but agencies are asked to submit a photo to be used in the announcement of their grant.

Grant Application

The Spirit of Blue Safety Grant Program is designed to award equipment, or in some cases training, that will protect officers serving on duty. You should only request items that you can articulate will have a positive impact on officer safety.

About

The Community Foundation of Central Georgia was founded in 1993 by a group of citizens interested in encouraging philanthropy and strengthening communities.

The Foundation provides donors a simple, powerful, and highly personal approach to giving. Through their funds, CFCG donors support the causes and organizations that they care about, which enhances the quality of life for the people of Central Georgia.

Our vision is a Central Georgia where philanthropy thrives, communities are strong, and citizens work toward common goals.

Al Lucas Memorial Scholarship Fund

Albert James “Big Luke” Lucas was born September 1, 1978, to David E. and Elaine H. Lucas. He passed away on April 10, 2005, from a spinal cord injury he suffered during a Los Angeles Avengers arena football game. He was married to De’Shonda, and had a daughter, Mariah.

Al was a native of Macon, Georgia, graduating from Northeast High School in 1996. Following graduation, he attended Troy State University on a full athletic scholarship, and shined as a defensive lineman for the Trojans. Throughout college Al studied hard and cherished his time on the field and in 2000 was awarded the distinguished Buck Buchanan Award as the top defensive player in Division 1-AA. He was also an outstanding member of Omega Psi Phi Fraternity, Inc. He graduated in 2000 with a Bachelor of Science degree in Criminal Justice. Al went on to join the National Football League, signing as a free agent with the Pittsburgh Steelers and later playing for the Carolina Panthers. Later he joined the Arena Football League, playing for the Tampa Bay Storm, and finally the Los Angeles Avengers.

Al was a strong athlete with a heart of gold who believed in giving back to the community that supported him over the years. He especially loved working with children and served as a substitute teacher and coach at Northeast High School during the off-season. He was a member of Steward Chapel A.M.E. Church where he first learned the responsibility and power of tithing.

Al Lucas exemplified the characteristics of a scholar-athlete. He loved athletics, but knew his studies came first. He served his community and the Lord. He expected the best of himself and others. He excelled on the football field and in life. Recipients of the Al Lucas Memorial Scholarship will reflect Al’s ideals and carry on his legacy of excellence.

Purpose

• To honor the memory of Al Lucas by providing college scholarships to scholar athletes in Al’s hometown of Macon, Georgia.

Awards

• Amount of Award: $1,000, non-renewable.
• Number of Awards: 7 per year. Two awards will be given to scholar-athletes graduating from Northeast High School, Al’s alma mater. One winner shall be female and one male. The other five awards will be given to student-athletes from each of the other five Bibb County public high schools. One will be awarded at each school.

The Clifton-Whitehead Scholarship Fund, established by Edward S. Whitehead, Jr. in honor of his relatives, supports deserving students in Middle Georgia, particularly in Bibb County. This fund aims to assist students of good character facing financial challenges in obtaining a college education. Annually, approximately 12 awards of around $1,000 are granted. Eligible recipients must maintain a minimum GPA and can renew the scholarship for up to four years, provided they meet the established criteria.

The Christine Riggins Shepherd Scholarship Fund, established by the Community Foundation of Central Georgia, aims to support students from Lamar, Pike, Monroe, Upson, or Spalding counties attending Georgia Southern University. With at least one award given annually, the scholarship amount varies. Recipients can renew their scholarships for up to four years if they maintain eligibility. Preference is given to applicants from Lamar County, promoting educational opportunities for local students.

The Career Women’s Network Scholarship Fund, established by the Community Foundation of Central Georgia, empowers non-traditional female students aged 25 and older to pursue higher education. This scholarship promotes leadership and personal development for women in the community, offering varying amounts each year. Recipients may renew their awards for up to four years, contingent on meeting eligibility criteria. The fund honors Katherine Walters, who valued education and aimed to assist women in achieving their academic goals.

Timothy S.Y. Lam Foundation

The mission of the Timothy S.Y. Lam Foundation is to support research, education, and training within the hospitality industry by bestowing scholarships and grants to those seeking careers or advancement in the hospitality industry; funding education programs that promote the hospitality industry; and awarding research grants to those interested in blending academia with practical industry know-how. 

Primary Goals: To support the professional development and academic advancement of the hospitality industry by continuing to support the foundation’s current programs, promote recipients, maintain positive working relationships with associations, and provide support to underserved communities with individuals pursuing hospitality education, training, and job advancement. 

In 2024, TSYLF introduced new initiatives to support and empower underserved communities and underprivileged and underemployed individuals. We invite all hospitality associations, students, research teams, and professionals to explore how the Timothy S.Y. Lam Foundation can support your educational and professional endeavors in the field of hospitality. 

Research Grants

Grantmaking Focus

The foundation supports programs that are practical and directly benefit the hospitality industry. Of particular interest are efforts that apply rigorous academic research to solve practical hospitality issues. All grants are measured on the direct results of improved efficiency and efficacy for the hospitality industry. The Foundation emphasizes activities in the following areas and organizations that work in the following areas:

• Research programs that improve employment possibilities and career advancement for those entering or incumbents in the hospitality industry.
• Research programs that enhance efficiency in the hospitality industry.
• Articles or textbooks that contribute to the comprehensive body of knowledge and/or promote industry practices, standards, and ethics.
• Practical and applicable research projects with immediate benefit to the hospitality industry.

Grants are payable to the organization or institution and not to an individual.

Grant funding is dispersed in two payments. One payment will be made upon award approval and the second will be made once the research grant report has been submitted.

Research Grant funding should be used for the following:

• TSYLF funds should be used for research facility overhead and general maintenance.
• TSYLF funds can be used for reasonable software, computer systems or programs to organize, track and store data.
• TSYLF funds can be used for tangible research items such printed documents, writing utensils, books, office supplies or related tools and materials needed to document research and practical observations.
• TSYLF will fund equipment or materials used for hands-on training such as cleaning, and sanitation supplies, safety items or other personal protection, furnishings found in hotels, restaurants or other hospitality related facilities being used to observe applicable productivity or conditions.
• TSYLF funds can be used to obtain proper permits for conducting research or staging a practical observation or production space.
• TSYLF funds can be used be used for creating resource material and related distribution costs to hospitality professionals, businesses and educators.
• TSYLF funds can be used for support materials or services for hosting focus groups, interviews or other activities related to the research topic.
• TSYLF funds should be used wisely for reasonable and cost-effective accommodations for staff, research team and subjects such as meals, travel or lodging.
• TSYLF funds can be used for reasonable mileage or transportation fees for research subjects, team and special advisors.
• TSYLF funds can be used for reasonable travel accommodations related to research topic data collection.
• TSYLF funds can be used for reasonable compensation to the research team for their time in collecting, analyzing and organizing data related to the funded research topic.
• TSYLF funds can be used for reasonable compensation to the research subjects.
• TSYLF funds can be used for expenses related to community engagement.
• TSYLF funds can be used for fees related to attending a hospitality event that aligns with the funded research topic.

About Community Alliance with Family FarmersOur mission is to build sustainable food and farming systems through policy advocacy and on-the-ground programs that create more resilient family farms, communities, and ecosystems. CAFF’s core values form the foundation on which we conduct our programs and activities. The values support our work, how we interact with each other, and how we fulfill our mission.

About California Underserved and Small Producer ProgramThe California Underserved and Small Producer (CUSP) Program is designed to facilitate support for small and medium scale California agricultural producers, or small and medium scale Socially Disadvantaged Farmers and Ranchers (SDFR’s) through technical assistance with business planning and financial and marketing strategies, and also provides direct farmer grants for drought relief for those same priority groups. Funding:

• Farmers can receive up to $20,000 in CUSP funding in a 12-month period, regardless of the granting organization(s).
• Eligible producers may receive up to $20,000 in CUSP Drought Relief funds as well as up to $20,000 in CUSP Extreme Weather Relief funds (for a total of up to $40,000) within a 12-month period (from date of CDFA approval/verification)

Agnes McCarthy Caregiver Foundation

The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.

Caregiver Grant

Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.

AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.

Additional Information

• To ensure our limited funds reach families with the greatest need, grants may require documentation confirming a diagnosed serious mental illness (SMI).  

• The $500 grant is limited to one award per household within a 12-month period.

• Applications are generally reviewed by our Board of Directors, with decisions made within 30 days of receipt.