Best San Francisco County Grants for Nonprofits in California

This funding opportunity aims to enhance the development of medical products in rare diseases through innovative natural history studies. By generating high-quality data, the FDA seeks to bridge critical knowledge gaps and eliminate barriers in rare disease research. The initiative focuses on diseases with unmet needs, fostering significant impacts for those affected and facilitating the development of effective therapeutic solutions.

The NARMS Cooperative Agreement Program aims to enhance antibiotic resistance surveillance in retail food specimens. Funded by the FDA, this initiative strengthens the National Antimicrobial Resistance Monitoring System established in 1996. By improving detection methods and expanding sampling sites, the program seeks to protect public health and align with NARMS objectives, ultimately combating the growing threat of antibiotic resistance in food commodities.

The RFA-FD-23-001 funding opportunity aims to support clinical trials for orphan products targeting rare diseases. It focuses on evaluating the efficacy and safety of treatments to address unmet medical needs. By promoting innovative and collaborative trial designs, the FDA seeks to enhance the approval rates of effective therapies for rare conditions, ultimately benefiting patients and advancing drug development in this critical area.

The Yéigo Action Grant, provided by the First Peoples Fund, offers financial support ranging from $100 to $2,500 for Native artists and culture bearers facing hardships that affect their creative practices. This grant aims to assist artists with specific professional opportunities, such as workshops or emergencies. By honoring the spirit of encouragement embodied in the Diné word 'yéigo', the grant helps ensure that artists can continue their vital work within their communities.

The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.

The Hunger to Health Collaboratory (H2HC) 2025 Prizes for Innovation aim to enhance health equity for youth through innovative funding in three categories: Food and Nutrition Policy, Nutrition Education & School Food, and Indigenous Food Justice. Supported by Newman’s Own Foundation, these prizes include $100K grants for policy work and $25K grants for education and justice initiatives. Winners will participate in the H2HC Fall Summit in Boston, fostering collaborative solutions to food challenges.

The George William Groh Trust Grant supports medical research initiatives by providing funding to organizations that qualify as exempt under Section 501(c)(3) of the Internal Revenue Code. Applications are accepted year-round, with a deadline of May 1 for consideration at the annual grant meeting. The foundation aims to enhance medical research efforts and contribute to advancements in healthcare.

The Elizabeth Hurlock Beckman Award Trust Grant honors educators who inspire students to create impactful organizations or movements. Established in 2008, the trust has awarded over $3.5 million to 148 professors across the U.S. The grant primarily supports those teaching in psychology, medicine, or law, emphasizing the importance of community contribution. Eligibility is limited to U.S. citizens or permanent residents who have inspired their former students to make a difference.

The Undergraduate Development Program Student Travel Award offers undergraduate science majors a unique opportunity to attend the Society of Toxicology Annual Meeting from March 21–23, 2026. The program aims to inspire students pursuing research careers in toxicology and related biomedical sciences. Participants will engage with professionals, attend sessions, and explore various educational and career paths. SOT emphasizes inclusiveness, encouraging diverse perspectives to enhance innovation in the field.

The Undergraduate Development Program Advisor Travel Award, hosted by the Society of Toxicology, enables faculty advisors to attend the Undergraduate Development Program from March 21-23, 2026. This initiative aims to familiarize advisors with toxicology and encourage them to guide students toward careers in biomedical sciences. Recipients of the award will participate in educational sessions, networking opportunities, and receive support for travel-related expenses, fostering diversity and innovation within the field.

The UPMC Microvascular Reconstructive Fellowship offers a one-year clinical program designed for qualified surgeons, focusing on mentorship in microsurgical techniques and comprehensive patient care. Participants will gain hands-on experience in reconstructive surgeries, including extremity trauma and facial reanimation, while also engaging in multidisciplinary cancer treatment. The fellowship emphasizes both clinical and didactic learning, with opportunities for research in renowned laboratories, ensuring fellows acquire a deep understanding of the field.

The Joan M. Wismer Foundation, established in 2001, honors the legacy of Joan Marilynn Wismer, who was dedicated to charitable work and community service. The foundation focuses on improving lives through education, youth development, safety, humanitarian services, and medical research. It primarily supports IRS-recognized 501(c)(3) organizations, schools, and churches, while emphasizing the importance of sustainable funding and effective financial management in its grant-making process.

The Art Bridges Cohort Program aims to enhance access to American art by fostering multi-year partnerships among museums across the U.S. This initiative creates sustainable art-sharing ecosystems that promote collaboration and community engagement. The program supports museums through funding for various phases, including research, small art shares, and large art shares, ensuring resources for travel, exhibition design, and educational opportunities. Eligibility includes a strong commitment to community engagement and existing art collections.

The Firehouse Subs Public Safety Foundation Scholarship Program supports students aiming to enroll in firefighter, law enforcement, or emergency medical programs at accredited institutions. Established in 2005, the foundation provides $5,000 scholarships to eligible candidates, including high school seniors and current college students. The program emphasizes commitment to public safety and community service, assisting those pursuing careers as first responders. This initiative highlights the foundation's dedication to enhancing lifesaving capabilities within local communities.

The AOFAS Resident Scholarship Program provides orthopaedic residents from the US and Canada the opportunity to attend the AOFAS Annual Meeting 2025 in Savannah, Georgia. Covering registration fees, lodging, and transportation, this program supports residents interested in foot and ankle surgery. Eligible applicants are PGY1, PGY2, or PGY3 residents who can attend the full program on September 10-11. This unique experience allows networking with leading surgeons and gaining insights into foot and ankle procedures.

The Traveling Fellowship Program, managed by the American Orthopaedic Foot & Ankle Society (AOFAS), offers mid-career members a unique chance to attend the AOFAS Annual Meeting and visit top research institutions. Participants will enhance their skills by observing surgeries, learning new techniques, and sharing their research experiences. The 2025 program runs from September 8-25, featuring visits to esteemed sites, including the University of South Carolina and the Rothman Institute.

The DARPA Tactical Technology Office (TTO) seeks innovative proposals to enhance national security through cutting-edge technology. This initiative focuses on Design/Build/Buy, Surge and Sustain, Long Range Effects, and Disruptive Innovation. By fostering rapid adaptation and sustainable force structures, TTO aims to demonstrate revolutionary systems that are not only effective but also affordable and responsive to emerging challenges.

The Washington Federal Foundation offers Community Impact Grants to support nonprofits serving low- and moderate-income populations. Focus areas include sustainable housing, economic development for small businesses, community revitalization, and job training programs. Eligible organizations must operate for at least 12 months and primarily serve LMI communities near a WaFd Bank branch. Note that funding is not available for medical endeavors, animal welfare, or arts projects unless they directly benefit LMI populations.

The F-gas Reduction Incentive Program (FRIP) aims to incentivize the adoption of ultra-low-global warming potential (GWP) refrigerant technologies in commercial and industrial sectors. By promoting these climate-friendly technologies, FRIP intends to reduce fluorinated gas emissions and support California's efforts to meet greenhouse gas reduction targets as mandated by Senate Bill 1383. The program focuses on achieving economies of scale to facilitate wider market adoption and enhance environmental sustainability.

The Outdoor Fund - Local Impact Grant supports local organizations and projects that enhance community engagement and align with conservation goals. With grants up to $5,000, eligible projects include youth fishing clinics and trail maintenance. Funded by Bass Pro Shops and Cabela’s, this initiative exemplifies their commitment to wildlife conservation and connecting communities to the outdoors. Eligible applicants include municipalities and registered nonprofits in the U.S. and Canada, focusing on specific conservation efforts.

Bass Pro Shops & Cabela's Outdoor Fund supports conservation-focused nonprofits through fundraising events and donation of merchandise or gift cards. Organizations eligible for funding must be registered 501(c)(3) entities in the U.S. or provincially registered nonprofits in Canada. This initiative aims to connect communities to outdoor activities while promoting wildlife conservation and support for military veterans. Grants of up to $1,000 are available to enhance local fundraising efforts.

The First Responders Outreach (FRO) Grant, provided by the Gary Sinise Foundation, supports essential resources for firefighters, police, and EMTs. This grant specifically targets First Responder Departments, allowing one application per year focused on equipment and training. It excludes funding for building costs and weaponry. This initiative aims to enhance the safety and preparedness of those who protect our communities during emergencies, ensuring they have the necessary tools and training to perform their vital roles effectively.

The One Hive Foundation Grant focuses on promoting pollinator health and ecologically responsible agriculture through funding research and nonprofit initiatives. Launched in 2022, the grant supports diverse projects aimed at enhancing environmental data, public education, and scientific collaboration. Targeting verified 501c3 organizations, the foundation emphasizes ecological practices and community engagement in Vermont and beyond, with grants of up to $75,000 available to eligible applicants.

The Opportunities for Collaborative Research at the NIH Clinical Center aims to foster high-quality translational research partnerships between NIH intramural and extramural investigators. This program supports projects that bridge basic biological discoveries with clinical applications, ultimately enhancing patient-centric research. By facilitating collaborations, the program seeks to accelerate scientific advancements leading to improved health outcomes through innovative therapeutic interventions and diagnostic strategies.

The David and Jacquie Clark Family Fund, established in 2017, aims to support individuals with special needs and their families through grants to nonprofits. With a focus on Ohio organizations, the fund seeks to ensure equitable opportunities for these individuals, fostering their success and well-being. Since its inception, the fund has provided assistance to over 30 nonprofits across the U.S., enhancing programs that promote learning and growth outside traditional educational settings.

The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.

The Andrea-Mennen Family Foundation Grant aims to enhance the quality of life for children and young adults facing mental and physical challenges. By supporting registered charitable organizations that align with its mission, the foundation seeks to ensure that 100% of grant funds directly benefit those in need within the US. Emphasizing immediate results and proven success, the foundation is dedicated to making a positive impact in the lives of future generations.