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Best Santa Cruz County Grants for Nonprofits in California

Discover active funding opportunities in Santa Cruz County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Los Angeles County, San Diego County, and Orange County.

10,000+

Available grants

$3.54B

Total funding

$5K

Median grant

10,000+ grants
$3.54B total
$5K median

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9,686 Results based on applied filters

BRAIN Initiative: Brain-Behavior Quantification and Synchronization – Transformative Research on Behavior at the Organismal Level

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The BRAIN Initiative's BBQS Program aims to revolutionize the study of brain function by facilitating high-resolution tracking of complex behaviors alongside neural activity. This transformative research opportunity seeks to develop innovative tools for minimally intrusive measurements of various biobehavioral functions while accounting for environmental variables. Emphasizing transdisciplinary collaboration, it focuses on creating new analytical frameworks that model neurobehavioral function as dynamic systems influenced by an organism's surroundings, thereby advancing our understanding of behavior at the organismal level.
Neuroscience Neurological Diseases & Disorders

Genomic Community Resources (U24 Clinical Trials Not Allowed)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Human Genome Research Institute (NHGRI) is launching a Notice of Funding Opportunity (NOFO) aimed at enhancing genomic research through the development and distribution of high-value resources. This initiative encourages collaborative efforts in genomic resource development and the integration of data science in clinical applications. While applications are not currently being accepted, prospective applicants are urged to prepare meaningful collaborations and projects ahead of the formal solicitation.
Cancer / Oncology Genetics & Genomics Human Genome & Genetics

Medical Scientist Training Program (MSTP)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.
Science Medical Education & Professional Training

Native American Research Centers for Health (NARCH)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The Native American Research Centers for Health (NARCH) program supports federally-recognized American Indian and Alaska Native Tribes and organizations in advancing health-related research. It aims to enhance research careers and infrastructure through a competitive application process. Funded by the US Dept. of Health & Human Services, this initiative invites eligible entities to apply, ensuring that only high-quality proposals undergo peer review for potential funding.
Native American Services Native American Culture & Heritage Indigenous Services

Network of the National Library of Medicine Regional Medical Libraries (UG4 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $600,000
The National Library of Medicine (NLM) is seeking applications to establish Regional Medical Libraries within the Network of the National Library of Medicine (NNLM). Since 1965, the NNLM has enhanced public health information access through partnerships with libraries and health organizations. The initiative aims to improve community engagement, disseminate NIH research findings, and foster collaborations to promote health literacy and access to biomedical data, thereby supporting local clinical research efforts.
Health & Medicine Library & Information Science Library Services

Network of the National Library of Medicine Training Center (U24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The National Library of Medicine (NLM) is seeking applications for a Training Center under the Network of the National Library of Medicine (NNLM). This initiative aims to enhance professional development for librarians, community engagement, and access to health information. By fostering partnerships and disseminating NIH resources, the NNLM will broaden its impact and improve public understanding of health data and information. The NTC will develop innovative training curricula and materials to meet diverse audience needs.
Health & Medicine Library & Information Science Library Services

Network of the National Library of Medicine Coordinating Center (U24 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $1,500,000
The National Library of Medicine (NLM) is inviting applications for its Coordinating Center within the Network of the National Library of Medicine (NNLM). Established in 1965, the NNLM enhances public access to health information through collaboration with libraries and community organizations. The NCC will oversee network administration and evaluation, fostering partnerships and supporting local clinical research. This initiative aims to expand NIH engagement and improve public understanding of health resources and information available through the NNLM.
Health & Medicine Library & Information Science Library Services

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $800,000
The HEAL Initiative Whole Joint Health Program aims to advance research on the biological mechanisms of joint pain by exploring the interactions of various tissues within the joint. This innovative program will support clinical studies that focus on non-pharmacological interventions to enhance healing and improve quality of life for individuals suffering from chronic joint pain. By fostering a comprehensive understanding of joint health, the initiative aligns with the NIH's broader goals to reduce chronic pain and opioid dependency.
Musculoskeletal Diseases Orthopedics

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Limited Competition Small Grant Program for the NCATS CTSA Program aims to empower KL2 scholars by funding diverse clinical and translational research projects. These grants support short-term studies, methodology development, and preliminary data collection, facilitating the transition to independent research careers. Applications will undergo NIH peer review, ensuring only high-quality proposals receive funding. This initiative fosters innovation in research methodologies and technology, ultimately enhancing the capabilities of emerging translational scientists.
Science Biology Health & Medicine +2 more

Collaborative Program Grant for Multidisciplinary Teams

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.
Science Biology Health & Medicine

HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HEAL Initiative's new program aims to generate comprehensive datasets on human pain networks through advanced 'omics and physiology research. Utilizing primary human tissues, the initiative promotes collaboration among diverse experts to enhance the understanding of pain mechanisms. This cooperative agreement will foster best practices and data sharing, ensuring integrated approaches across various pain conditions. While applications are not currently being accepted, the initiative encourages multidisciplinary teams to prepare for future opportunities in pain research.
Human Physiology Human Genome & Genetics

RAK Education Foundation Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The RAK Education Foundation Scholarship provides financial assistance to residents of Camden, Chowan, Gates, Pasquotank, or Perquimans Counties who have earned a high school diploma or GED. This scholarship supports students pursuing degrees or certificates in Career and Technical Education fields such as trade education, computer science, business, health science, and more. Applications open on December 16, 2025, and close on March 3, 2026, encouraging eligible students to apply.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Robert E. Barnhill, Sr. Scholarship Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Robert E. Barnhill, Sr. Scholarship Fund provides financial support for North Carolina high school seniors who plan to attend a four-year college or university as full-time students. Eligible applicants are evaluated on leadership potential, community involvement, academic achievement, and financial need. The scholarship may be renewed for up to three additional years, contingent upon maintaining a 2.0 GPA and continuous enrollment. Applications open on December 16, 2025, and close on March 3, 2026.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Ruby A. Trivette Ruritan Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Ruby A. Trivette Ruritan Scholarship, administered by the North Carolina Community Foundation, supports graduating seniors from Ashe and Watauga counties in North Carolina. Eligible applicants must reside in Todd or be active members or children of active members of the Todd Ruritan Club. This scholarship opens for applications on December 16, 2025, and closes on March 3, 2026, providing crucial financial assistance for students pursuing higher education.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Sammy and Shirley Church Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Sammy and Shirley Church Scholarship supports students from Ashe County, NC, including those graduating from the NC School of Science and Math. Eligible candidates must demonstrate academic excellence, physical vigor, and leadership in various activities. Financial need is considered but not the only criterion. Applications open on Dec. 16, 2025, and close on March 3, 2026. Ensure to meet specific eligibility requirements set by the donor for successful application.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

The Bertha Sawyer Meiggs & Winfred B. Meiggs Sr. Family Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Bertha Sawyer Meiggs & Winfred B. Meiggs Sr. Family Scholarship supports graduating seniors from Camden, Gates, Pasquotank, and Perquimans counties, with a preference for Camden County residents. Eligible candidates must demonstrate strong academic performance, leadership skills, and community involvement while enrolling full-time in a two- or four-year college. The scholarship may be renewed at the discretion of the Scholarship Committee, subject to academic criteria and available funds.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

The Reid Sasnett Memorial Scholarship Endowment

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Reid Sasnett Memorial Scholarship Endowment supports graduating seniors from Pungo Christian Academy and Beaufort County high schools pursuing higher education. This scholarship aims to aid students who exhibit strong character, leadership, and community service, especially those passionate about agriculture and wildlife. Applications open on Dec. 16, 2025, and close on March 3, 2026, with preference for volunteer firefighters and Pungo Academy alumni.
Education - Higher Education Education - High School Academic Scholarship Programs +1 more

Scholarships for Careers Endowment

Community Foundation of the Endless Mountains (CFEM)
Association/Society
United States
Unspecified amount
The Scholarships for Careers Endowment, established by a local family in connection with the Community Foundation of the Endless Mountains, aims to support graduates of Elk Lake School District and the Susquehanna County Career & Technology Center. This scholarship prioritizes students with financial need and promise for future success, assisting them in pursuing vocational, technical, academic, or other post-secondary programs. Additionally, it contributes to special projects within the school district and community.
Education - Higher Education Vocational & Trade Education

California Permitting Academy

California Governor's Office of Business and Economic Development
State/Local Government
California
US $0
The California Permitting Academy aims to enhance local government efficiency in permitting processes through targeted training and technical assistance. This initiative, led by the Governor's Office of Business and Economic Development, will provide in-person, one-week courses for representatives from multiple local governments. Participants will gain valuable skills in streamlining permits, ensuring compliance, and implementing continuous improvement strategies. The program focuses on modernizing practices and fostering collaboration among local agencies to better support zero-emission vehicle infrastructure and clean energy projects.
Entrepreneurship Business Education Business Development

County Medical Services Program Loan Repayment Program (CMSPLRP) 2026 Application

California Department of Health Care Access and Information
State/Local Government
California
Unspecified amount
The County Medical Services Program Loan Repayment Program (CMSPLRP) aims to attract and retain healthcare professionals in California by offering educational debt relief for those providing primary care or dental services in designated CMSP counties. This program supports the repayment of qualified educational loans, enhancing local healthcare delivery and ensuring access to quality medical services for underserved populations.
Microfinance

Song Brown Registered Nurse Education Programs (RN) 2026 Application

California Department of Health Care Access and Information
State/Local Government
California
Up to US $300,000
The Song-Brown program aims to enhance healthcare in California's underserved areas by funding institutions that train primary care health professionals, particularly Registered Nurses. This initiative focuses on recruiting trainees committed to serving in these communities, implementing counseling and placement programs, and providing preceptorship experiences to ensure graduates are prepared to meet the healthcare needs of the population.
Nursing Medical Education & Professional Training

Song-Brown Certified Nurse Midwifery (CNM) Training Programs

California Department of Health Care Access and Information
State/Local Government
California
US $182,000 - US $225,000
The Song-Brown Certified Nurse Midwifery Training Programs aim to support organizations training nurse midwifery students for underserved areas in California. This initiative includes recruiting students committed to serving in these communities, providing counseling and placement support, and offering relevant preceptorship experiences. By addressing the shortage of healthcare professionals in critical regions, the program enhances access to primary care and improves health outcomes for vulnerable populations.
Medical Education & Professional Training

Song Brown Family Nurse Practitioner and Physician Assistant (FNP & PA) 2026 Application

California Department of Health Care Access and Information
State/Local Government
California
Unspecified amount
Purpose

The Song-Brown program funds institutions that train primary care health professionals to provide healthcare in California’s medically underserved areas.

Description:

This grant opportunity will result in funding organizations to train primary carenurse practitioners and physician assistant trainees to work in underservedcommunities. Such strategies shall incorporate the following elements:

  • Establishing procedures to identify, recruit and admit primary care nursepractitioner and physician assistant trainees who possess characteristicswhich would suggest a predisposition to practice in areas of unmet need, andwho express a commitment to serve in areas of unmet need.
  • Implementing counseling and placement program to encourage trainingprogram graduates to enter practice in areas of unmet need.
  • Providing a preceptorship experience in an area of unmet need to enhancethe potential of training program graduates to practice in such an area.
Indigenous Health Systems Primary Health Care

Fred and Betty Worsh Scholarship Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Fred and Betty Worsh Scholarship Fund, managed by the North Carolina Community Foundation, offers financial support to residents of New Hanover and Brunswick Counties who are U.S. citizens attending accredited four-year colleges or universities. Scholarships are available to undergraduates, graduates, and adult re-entry students, and may be renewed annually based on academic performance and financial need. Applications open on December 16, 2025, and close on March 3, 2026.
Education - High School Academic Scholarship Programs STEM / STEAM Education

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

North Carolina Community Foundation Inc
Private
United States
More than US $1,000

Scholarships

We partner with donors to administer scholarships for students across the state. Most NCCF scholarships open for applications on Dec. 16, 2025, and close on March 3, 2026.

Undergraduates, graduates, medical and professional school students and adult re-entry students who are attending community colleges, four-year universities, career/technical schools, teaching credential programs and graduate, medical or professional schools in the United States are eligible for scholarships offered at NCCF.

Each scholarship has specific eligibility requirements defined by the donor when the scholarship was established. Be sure to read the requirements of each scholarship carefully as directed through the universal application and address those elements as needed in your application.

Grayce Wills MacDonald and Ivan A. MacDonald Endowment

Shall support students who attended high school in Cherokee, Graham, Clay, Swain, Macon, Jackson, Haywood, Buncombe, and Henderson counties, and who are pursuing a college or post-graduate level degree in the field of nutrition with emphasis on the study of natural foods and the vegetarian lifestyle. Scholarships may be based on both need and merit.

Education - Higher Education Education - High School Academic Scholarship Programs +2 more

JADE Learning Electrical Technologies Scholarship

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The JADE Learning Electrical Technologies Scholarship supports students enrolled in North Carolina technical or occupational schools focused on electrical systems technologies. Eligible candidates include undergraduates, graduates, and apprentices who demonstrate financial need and strong academic performance. The scholarship application requires careful attention to specific donor-defined eligibility criteria. Applications open on December 16, 2025, and close on March 3, 2026, with preference given to those pursuing a two-year associate’s degree.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Joyce Price Johnson’s Samaritan Fund

North Carolina Community Foundation Inc
Private
United States
More than US $1,000
The Joyce Price Johnson’s Samaritan Fund provides scholarships for young people in North Carolina who are exiting foster care or facing poverty. Eligible candidates include undergraduates, graduates, and adult re-entry students attending various accredited institutions. Applications for NCCF scholarships open on December 16, 2025, and close on March 3, 2026. Preference is given to applicants from Wayne County and adjacent areas, ensuring support for those with exceptional financial need.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Santa Cruz County Grants for Nonprofits Highlights

Looking for Santa Cruz County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Santa Cruz County grants recommended for your specific programs in California.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Santa Cruz County Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

100 Santa Cruz County grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

22 Santa Cruz County grants for nonprofits over $25K in average grant size

14 Santa Cruz County grants for nonprofits over $50K in average grant size

17 Santa Cruz County grants for nonprofits supporting general operating expenses

66 Santa Cruz County grants for nonprofits supporting programs / projects

2,000+ Grants on Instrumentl focused on Career / College Preparation

2,000+ Grants on Instrumentl focused on Art & Culture

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Santa Cruz County grants for Nonprofits?

Most grants are due in the first quarter.

Q1
35.4%
Q2
23.2%
Q3
17.5%
Q4
24.0%

Typical Funding Amounts

What's the typical grant amount funded for Santa Cruz County Grants for Nonprofits?

Grants are most commonly $7,250.

$500 $500 Min.
$7,250 $7.3 K Median
$123,663 $123.7 K Average
$2,300,000 $2.3 M Max.

Average Grant Size

What's the typical amount funded for California?

Grants are most commonly $145,539.

$145,539

Total Number of Grants

What's the total number of grants in Santa Cruz County Grants for Nonprofits year over year?

In 2024, funders in California awarded a total of 256,564 grants.

2022 237,186

2023 236,635

2024 256,564

Top Grant Focus Areas

Among all the Santa Cruz County Grants for Nonprofits given out in California, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Santa Cruz County Grants for Nonprofits changing over time?

Funding has increased by -1.38%.

2022 $34,364,756,699

2023 $37,770,770,141
9.91%

2024 $37,247,795,891
-1.38%

California Counties That Receive the Most Funding

How does grant funding vary by county?

Los Angeles County, San Francisco County, and San Mateo County receive the most funding.

County Total Grant Funding in 2024
Los Angeles County $10,841,756,858
San Francisco County $5,409,542,294
San Mateo County $5,358,878,304
Santa Clara County $3,811,026,208
Alameda County $3,749,322,182

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