South Dakota Community Programs Funding via US Bancorp Foundation
South Dakota 501(c)(3) nonprofits working on economic and workforce advancement, affordable housing, or community arts and culture can access funding through US Bancorp Foundation’s Community Possible program. Organizations serving MS patients may be eligible if their programs fit these priorities, especially those advancing equity and led by people of color in designated U.S. Bank communities.
US Bancorp Foundation
Costco Foundation Health Grants in South Dakota
Nonprofit 501(c)(3) organizations in South Dakota that support children, education, or health and human services can apply for monetary program funding, which may benefit multiple sclerosis patients and their families. Grants from Costco Foundation help U.S. community-based programs that demonstrate measurable outcomes, address unmet needs, and show strong collaboration and diversified financial support.
Costco Wholesale Corporation
Youth Welfare Funding for Nonprofits from DanPaul Foundation
501(c)(3) nonprofits serving youth health, education, and welfare worldwide, including South Dakota, can apply for DanPaul Foundation grants up to US $15,000 for direct-service programs. Funding may support child advocacy, homelessness and poverty services, clean air and water education, refugee enrichment, early childhood development, or related youth-focused initiatives.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants for Innovation
Early-stage, impact-first nonprofits and mission-driven for-profits working on scalable social or environmental solutions in South Dakota can access funding through Draper Richards Kaplan Foundation; awards up to US $300,000 for capacity, capital, and community support. Organizations serving underserved populations, with proven pilots and strong growth potential, may include programs benefiting multiple sclerosis patients.
Draper Richards Kaplan Foundation
Tech-Enabled Social Impact Funding from Cisco
Nonprofits and NGOs using technology for crisis response, education access, economic empowerment, or climate resilience worldwide, including South Dakota, can seek Global Impact Cash Grants to scale innovative programs serving mostly economically underserved communities. Cisco Systems Foundation offers up to US $100,000, with a year-round LOI process for early-stage, high-potential solutions that expand reach and efficiency.
Cisco Systems Foundation
Community Safety and Education Grants from State Farm
South Dakota nonprofits, educational institutions, government programs, and volunteer fire companies working on safety, education, or community development can access funding through State Farm Companies Foundation’s Good Neighbor Citizenship Company Grants. Projects may include disaster preparedness and recovery, affordable housing, food insecurity, financial literacy, job training, or K-12 and higher education initiatives, including STEM and college-career pathways.
State Farm Companies Foundation
William Randolph Hearst Foundation Culture Grants in South Dakota
South Dakota cultural nonprofits offering arts, science, or STEAM programming can access funding through the William Randolph Hearst Foundation for program, capital, and limited general or endowment support. U.S.-based 501(c)(3) institutions such as museums, performing arts organizations, and arts schools serving large audiences may be eligible for awards of more than US $100,000.
William Randolph Hearst Foundation
South Dakota Social Service Funding via Hearst Foundation
South Dakota nonprofits providing social services that address chronic poverty and economic hardship can access funding through William Randolph Hearst Foundation for program, capital, or general support. U.S.-based 501(c)(3) organizations with audited expenses over $2 million and strong, scalable outcomes in areas like housing, food access, legal aid, reentry, or youth development may be eligible for awards over US $100,000.
William Randolph Hearst Foundation
LabCorp Charitable Foundation Grants
The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Youth Grants
Organizations serving children and youth in education, health, or family economic stability can apply for Michael & Susan Dell Foundation grants of more than US $50,000 to support or scale projects; eligible entities include nonprofits, social enterprises, schools, and governments. South Dakota programs may be eligible if they meet the foundation’s focus areas and country criteria.
Michael & Susan Dell Foundation
Community and Health Funding for Charities from Roche
Charitable organizations running humanitarian, social development, science education, community, environmental, or arts programs in South Dakota and worldwide may be eligible for support, especially when projects engage Roche expertise and staff. Focused on impactful, accredited-charity projects, Roche invites applications that could benefit people living with multiple sclerosis through health, education, or community services.
La Roche, Inc.
Health and Humanitarian Funding from Semnani Family Foundation
Nonprofit organizations providing health, education, or humanitarian services can seek support for programs serving marginalized communities worldwide, including the U.S. Semnani Family Foundation provides South Dakota multiple sclerosis organizations with potential funding for health care access, disease-related services, and vulnerable patient support within its broader global mission.
Semnani Family Foundation
Sidney Stern Memorial Trust Grants for South Dakota Nonprofits
With a mission to strengthen charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides South Dakota 501(c)(3) organizations with funding for programs that advance general welfare. Eligible nonprofits must use awarded funds within the U.S., may work on multiple sclerosis-related services or research, and must be tax-exempt under federal and, if applicable, California law.
Sidney Stern Memorial Trust
Bank of America Support for Community Programs
Nonprofit 501(c)(3) organizations in South Dakota seeking support for community-focused programs can apply for Bank of America Foundation’s sponsorships. Bank of America supports initiatives in basic needs, housing, workforce development, community development, arts and culture, environment, and diversity and inclusion, which may benefit organizations serving people with multiple sclerosis.
Bank Of America Charitable Foundation Inc
South Multiple Sclerosis Funding via Robinson Foundation
Applications due Oct 15, 2026
South Dakota nonprofits serving multiple sclerosis patients and related health or poverty needs can access funding through Robinson Foundation if they are 501(c)(3)s active for over three years and serving the Southern region. Grants support single-year projects with tangible, meaningful impact; facilities and capital projects are not funded.
Robinson Foundation
Dudley T Dougherty Foundation Support for Community Services
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding can apply for funding that may benefit multiple sclerosis patients in South Dakota. Focused on broad, positive change, the Dudley T Dougherty Foundation supports charitable initiatives that respect people, the environment, and life in an ever-changing world.
Dudley T Dougherty Foundation Inc
Youth and Basic Needs Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations supporting basic needs, at-risk youth, or domestic violence services near TJX locations, including South Dakota, can apply for TJX Foundation grants. Programs that help vulnerable families and children, including those affected by health challenges like multiple sclerosis, may be eligible if they meet mission alignment and distance, nondiscrimination, and prior-funding requirements.
The Tjx Foundation Inc
Lawrence Foundation Grant
Applications due Nov 1, 2026
The Lawrence Foundation is a private family foundation established in 2000, dedicated to granting funds for environmental and human services causes. Eligible organizations include 501(c)(3) nonprofits and public schools, with grants typically ranging from $5,000 to $10,000. The foundation supports unrestricted grants for various projects, including disaster relief and environmental programs, but does not fund individuals or for-profit entities. Applications are evaluated based on alignment with the foundation's priorities.
Lawrence Foundation
Max and Victoria Dreyfus Foundation Grants for South Dakota Community Programs
Applications due Nov 11, 2026
The Max and Victoria Dreyfus Foundation provides South Dakota nonprofits with US $1,000 - US $20,000 for community-based programs, including education, cultural institutions, health facilities, and services for youth, seniors, and people with disabilities. Organizations supporting multiple sclerosis patients through clinics, rehabilitation, life skills, or related community services may be eligible if they are IRS-qualified U.S. nonprofits.
Max and Victoria Dreyfus Foundation
Spark Good: Strengthening Community - Local Grants
Applications due Nov 30, 2026
The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.
Wal-Mart Foundation
Nordstrom Community Grant
Applications due Jan 31, 2027
The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.
Nordstrom
Dr Scholl Foundation Grants for Health Programs
Letter of inquiry due Feb 1, 2027
Nonprofit 501(c)(3) organizations working on health care, social services, education, civic, cultural, or environmental programs in the U.S., including South Dakota, can seek project funding from the Dr Scholl Foundation. Grants from Dr Scholl Foundation help organizations that may support multiple sclerosis patients or related services with US $5,000 - US $25,000 awards.
Dr Scholl Foundation
Hansen Family Foundation Humanitarian Grants in South Dakota
Applications due Mar 23, 2027
South Dakota nonprofits with 501(c)(3) status seeking $1,000 - US $10,000 for humanitarian, health-related, or basic human needs programs can access funding through Hansen Family Foundation. Organizations serving multiple sclerosis patients may be eligible if their work fits the foundation’s focus on children, education, humanitarian aid, and related community support priorities.
Hansen Family Foundation
Storytelling Funding for Nonprofits from Couch Foundation
Letter of inquiry due Mar 27, 2027
Nonprofit 501(c)(3) organizations and aligned for-profits seeking support to tell impactful stories about their work can apply for the Storytelling Grant, with awards of more than US $50,000. Focus areas include preservation, education, wellness, and wildlife conservation, which may benefit South Dakota programs serving people living with multiple sclerosis.
Jesse W Couch Charitable Foundation
O'Reilly Automotive Foundation Grants for Community Health
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations addressing community health, economic stability, workforce development, or disaster relief in South Dakota communities with an O’Reilly Auto Parts presence may be eligible for this funding. Grants from O'Reilly Automotive Foundation help U.S. organizations serving underserved people, which can include programs supporting multiple sclerosis patients through health and social services or access to care.
O'Reilly Automotive Foundation Inc
Community Partnership Grants for Nonprofits from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations in South Dakota with strong, replicable community partnerships addressing significant social issues can apply for Mutual of America Foundation’s national Community Partnership Award. Eligible U.S. nonprofits, including those serving multiple sclerosis patients through cross-sector collaboration, may be recognized for exemplary leadership, measurable impact, and innovative partnership models that benefit their communities.
Mutual Of America Foundation
South Dakota Human Services Funding via Gupta Family Foundation
Applications due Jul 31, 2027
Non-sectarian human and social service nonprofits working to help disadvantaged people become self-reliant, including those serving multiple sclerosis patients, can apply for Gupta Family Foundation support; awards range from US $5,000 - US $250,000. With a mission to empower disadvantaged individuals, the foundation funds smaller 501(c)(3) and qualifying foreign organizations operating in several countries, including the U.S.
Gupta Family Foundation