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Best Grants for 501(c)(3) in South Carolina

Find the perfect Grants for 501(c)(3) in South Carolina on Instrumentl. 9,000+ Grants for 501(c)(3) in South Carolina in the United States.

9,000+

Available grants

$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

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9,315 Results based on applied filters

Point Foundation- Flagship Scholarship

Point Foundation
Private
United States
Unspecified amount
The Point Foundation Flagship Scholarship is dedicated to empowering LGBTQ students pursuing undergraduate, graduate, and doctoral degrees at accredited U.S. institutions. It provides financial assistance, mentoring, and leadership development opportunities, ensuring these students have the support necessary to excel academically and professionally. Scholarships are renewable for up to four years, and recipients benefit from a vibrant community of scholars and alumni, enhancing their educational journey and future career prospects.
LGBTQIA+ Services Education - Higher Education

Dermatologist Investigator Research Fellowship

Dermatology Foundation
Private
United States
US $35,000
The Dermatology Foundation's Dermatologist Investigator Research Fellowship offers $30,000 to advance early-career researchers in dermatology. This fellowship is designed for dermatologists committed to an academic career in medical and surgical dermatology. It supports research training for those with substantial experience in other fields transitioning to skin research. Eligible candidates must meet specific educational and training criteria, ensuring focused dedication to cutaneous research while adhering to funding guidelines.
Skin Diseases & Dermatology

Accelerator Programs: Reach Grant

Alex’s Lemonade Stand Foundation for Childhood Cancer
Private
Canada, United States
Up to US $250,000
The Accelerator Programs: Reach Grant, offered by Alex’s Lemonade Stand Foundation, aims to bridge gaps in pediatric cancer research by funding pre-clinical studies necessary for clinical trial readiness. With a mission rooted in Alex Scott’s legacy, the program supports innovative research that can lead to effective treatments for children with cancer. By facilitating the transition from laboratory to clinical settings, the Reach Grant plays a crucial role in advancing pediatric oncology and improving outcomes for young patients.
Cancer / Oncology

R Accelerated Award Grants

Alex’s Lemonade Stand Foundation for Childhood Cancer
Private
Canada, United States
Up to US $800,000
The R Accelerated Award Grants by Alex's Lemonade Stand Foundation aim to support innovative pediatric oncology research. These grants are designed for early-career scientists focused on developing less toxic therapies for childhood cancers. Eligible applicants must be first-time principal investigators with a strong institutional backing and a commitment to pediatric cancer research. The program emphasizes the importance of scientific rigor and aims to accelerate the discovery of effective treatments, thereby improving outcomes for children with cancer.
Cancer / Oncology

Stephen P. Taylor Scholarship Fund

San Antonio Area Foundation
Private
United States
Unspecified amount
The Stephen P. Taylor Scholarship Fund, managed by the San Antonio Area Foundation, supports current college students pursuing Bachelor's, Associate's, or Technical/Vocational degrees. This renewable scholarship aims to assist individuals who are either enrolled full-time or part-time and demonstrates financial need. Eligible applicants must reside or work in Texas, Arkansas, Louisiana, Oklahoma, or New Mexico and maintain a minimum 2.5 GPA. Since 1964, millions have been awarded to enhance community quality of life.
Education - Higher Education Academic Scholarship Programs

San Antonio Area Foundation: Legacy Scholars

San Antonio Area Foundation
Private
United States
US $10,000
The San Antonio Area Foundation's Legacy Scholars program provides substantial scholarships to high school juniors in Bexar and Webb counties. Focusing on students with proven leadership and community involvement, this initiative aims to bridge opportunity gaps and support education in all areas of study. With renewable funding for up to three years, the program promotes attendance at Texas colleges, encouraging students to participate in events that foster their academic success and community engagement.
Education - Higher Education Academic Scholarship Programs

Gadsden Family Fund

Coastal Community Foundation of South Carolina
Private
Berkeley County, South Carolina, Dorchester County, South Carolina
Approximately US $600
The Gadsden Family Fund, established in 1983, supports residents of Berkeley and Dorchester Counties in South Carolina by providing scholarships for education at Winthrop and Clemson Universities. Managed by the Coastal Community Foundation, the fund exemplifies community commitment, addressing pressing needs through strategic grantmaking and fostering local initiatives. This initiative reflects a dedication to equity and opportunity, ensuring that deserving students can pursue their academic goals and contribute positively to their communities.
Education - Higher Education Academic Scholarship Programs

Small Animal Theriogenology Residency Program Grant

American Kennel Club Canine Health Foundation Inc
Private
United States
Up to US $150,000
The Small Animal Theriogenology Residency Program Grant, supported by the American Kennel Club (AKC), AKC Canine Health Foundation, and Theriogenology Foundation, invites proposals from accredited veterinary schools in the U.S. to fund residency positions in canine reproductive health. With funding up to $150,000, the program aims to advance training in clinical genetics and prepare candidates for board certification, ultimately enhancing the health of purebred and purpose-bred dogs.
Veterinary Science & Services Animal Welfare - Domestic Animals & Pets

Jean Estes Epstein Charitable Foundation Scholarship

Hawai'i Community Foundation
Private
United States
Unspecified amount
The Jean Estes Epstein Charitable Foundation Scholarship supports public school students from Hawaii in their pursuit of higher education on the mainland U.S. Established by Jean Estes Epstein in 2007, the scholarship aims to enhance educational experiences by exposing students to diverse environments. Eligible candidates must be Hawaii residents, graduating from public high schools with a minimum GPA of 3.7, and demonstrate financial need while being full-time college freshmen.
Academic Success & Enrichment Academic Scholarship Programs

nccPA Health Foundation: Mental Health - Community Outreach Grant

nccPA Health Foundation
Association/Society
United States
Up to US $3,500
The nccPA Health Foundation's Mental Health - Community Outreach Grant supports innovative PA-led projects aimed at improving mental health awareness and reducing stigma in communities. With funding up to $2,500, this grant encourages collaboration among PAs, PA students, and organizations to address the mental health needs of vulnerable populations. Applications are accepted year-round, promoting ongoing community engagement and systemic change through education, prevention, and treatment initiatives.
Mental Health & Psychiatric Diseases

AFM Local 802 Musicians’ Emergency Relief Fund

Entertainment Community Fund
Association/Society
United States
Unspecified amount
The AFM Local 802 Musicians’ Emergency Relief Fund provides emergency financial assistance to eligible performing arts and entertainment professionals facing unexpected critical needs. This fund supports basic living expenses, including healthcare, housing, and utilities, to help prevent eviction or shut-offs. To qualify, applicants must be current members in good standing and demonstrate financial need. However, the fund does not cover expenses such as credit cards, personal loans, and tuition.
Basic Human Needs Disaster Relief / Humanitarian Aid

PFF Research Fund to Cure Pulmonary Fibrosis - PFF Scholars

Pulmonary Fibrosis Foundation
Private
United States
US $100,000
The PFF Research Fund to Cure Pulmonary Fibrosis aims to support innovative research that enhances understanding and treatment of pulmonary fibrosis. The PFF Scholars Program provides $100,000 over two years to early-stage researchers, encouraging them to pursue independent funding opportunities. Eligible applicants include post-doctoral trainees and early Assistant Professors committed to interstitial lung disease research. This initiative fosters mentorship and collaboration, ultimately advancing the field and improving patient care.
Respiratory Diseases & Systems

American Guild of Musical Artists Relief Fund

Entertainment Community Fund
Association/Society
United States
Unspecified amount
The American Guild of Musical Artists Relief Fund provides emergency financial assistance to eligible performing arts professionals facing unexpected critical needs. This support aids in covering essential living expenses, including housing, healthcare, and utilities, to help prevent eviction or utility shut-offs. Applicants must be current members in good standing and provide necessary documentation to confirm their eligibility. This fund aims to ensure the well-being of artists during challenging times.
Basic Human Needs Disaster Relief / Humanitarian Aid

Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $1,750,000
This funding opportunity aims to foster innovative mechanistic research on precision probiotic therapies, utilizing a phased R61/R33 award mechanism. The goal is to identify and understand individual variations influencing probiotic responses, thereby enhancing clinical outcomes. The R61 phase focuses on uncovering unique biological patterns over two years, while the R33 phase applies findings to improve probiotic responsiveness through rigorous studies. Ultimately, this initiative seeks to overcome barriers in personalized probiotic interventions.
Microbiomes

Most Valuable Student Scholarship

Elks National Foundation Inc
Private
United States
US $1,000 - US $7,500
The Most Valuable Student Award, offered by the Elks National Foundation, provides scholarships ranging from $1,000 to $7,500 annually for U.S. high school seniors pursuing a four-year degree at accredited colleges or universities. This initiative aims to support students who demonstrate academic excellence and community involvement, ensuring they have access to education that fosters personal and professional growth. For more information, please visit the Elks Foundation website.
Academic Scholarship Programs Education - Higher Education

Phillip O’Neill Hanvey Memorial Scholarship Fund

Coastal Community Foundation of South Carolina
Private
Charleston County, South Carolina
US $1,500 - US $2,000
The Phillip O’Neill Hanvey Memorial Scholarship Fund, established in 1963 and managed by the Coastal Community Foundation since 1990, aims to support Charleston County students in their pursuit of higher education. Through this fund, the Foundation enhances educational opportunities, demonstrating its commitment to fostering equitable access and community well-being. This initiative is part of a broader mission to invest in community resources that help address structural challenges and promote a brighter future for the region's youth.
Education - Higher Education Academic Scholarship Programs

Cottrell Scholar Award

Research Corporation
Private
Canada, United States
US $120,000
The Cottrell Scholar Award supports early career faculty at U.S. and Canadian research universities, fostering innovative research and teaching in Chemistry, Physics, and Astronomy. This prestigious recognition emphasizes the importance of impactful research plans and educational strategies, aiming to enhance undergraduate and graduate science education. The award also encourages academic citizenship and collaboration within institutions, providing funding for three-year projects up to $120,000, thereby promoting excellence in both research and education.
Chemistry Physics Astronomy & Astrophysics

NASPGHAN Foundation/CPNP Nutrition Research Grant

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
Association/Society
Canada, Mexico +1 more
US $500 - US $5,000
The NASPGHAN Foundation offers a one-year grant to pediatric dietitians aimed at enhancing nutrition care for children with nutritional disorders. Grants ranging from $500 to $5000 will be awarded, with funding distributed in December 2025. Applicants must be Registered Dietitians, CPNP members in good standing, and have a sustained interest in pediatric nutrition. Recipients are required to provide a financial statement and present findings at the 2027 CPNP annual symposium.
Nutrition & Healthy Eating

Coca-Cola Scholars Program Scholarship

Coca-Cola Scholars Foundation
Association/Society
United States
US $20,000
The Coca-Cola Scholars Program Scholarship is an esteemed, achievement-based scholarship aimed at high school seniors committed to leadership and community service. Annually, 150 scholars receive $20,000 to support their college education. Since its inception, the program has awarded over $87 million in educational funding to more than 7,000 students. Eligible applicants must be U.S. citizens or permanent residents, planning to attend an accredited college, and demonstrate strong community leadership and service.
Education - Higher Education Academic Scholarship Programs

NASPGHAN IBD Young Investigator Award - Career Development Awards

Crohns And Colitis Foundation Inc
Private
United States
US $102,500 - US $307,500
The Crohn's & Colitis Foundation/NASPGHAN IBD Young Investigator Award supports early-career researchers in inflammatory bowel disease (IBD). This three-year grant offers mentorship and funding up to $60,000 annually, plus additional support for research-related expenses. Eligible applicants must hold an MD or PhD, demonstrate relevant research experience, and commit at least 65% of their time to the project. The award also facilitates access to IBD Plexus resources, enhancing research capabilities in the field.
Digestive System Health & Diseases

NASPGHAN Foundation/NASPGHAN George Ferry Young Investigator Development Award

North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
Association/Society
Canada, Mexico +1 more
US $150,000
The NASPGHAN Foundation/NASPGHAN George Ferry Young Investigator Development Award supports promising clinical, quality improvement, translational, or basic science research focused on gastrointestinal tract diseases, liver, pancreas, and nutritional disorders in children. Eligibility includes being a NASPGHAN member for at least two years, having a recent fellowship, and holding a junior faculty position. This award fosters innovative research to enhance pediatric gastroenterology and improve child health outcomes.
Digestive System Health & Diseases

Stein Innovation Award

Research To Prevent Blindness Inc
Private
United States
Up to US $300,000
The Stein Innovation Award supports innovative vision research by providing funding to Department of Ophthalmology faculty and other researchers. With deadlines in January and July, the award encourages projects that advance the understanding of the visual system and related diseases. Eligible candidates must be affiliated with U.S. institutions of higher education, and prior nomination forms are required for application acceptance. This initiative aims to foster groundbreaking research in the field of ophthalmology.
Eye Diseases & Disorders

Medical Student Eye Research Fellowship

Research To Prevent Blindness Inc
Private
United States
Approximately US $30,000
The Medical Student Eye Research Fellowship offers a unique opportunity for medical students to dedicate a year to research in ophthalmology, focusing on any vision-related topic. Supported by Research to Prevent Blindness and other partners, the fellowship includes a $30,000 grant and potential additional funding for relocation. Eligible candidates must be U.S. citizens or permanent residents and be nominated by RPB-supported Chairs. The program aims to promote diversity and innovation in vision research.
Eye Diseases & Disorders

Elks National Foundation: Legacy Awards

Elks National Foundation Inc
Private
Panama, Philippines +2 more
US $4,000
The Elks National Foundation's Legacy Awards provide $4,000 scholarships for children and grandchildren of Elks members. Eligible applicants must be high school seniors and can apply online. The program supports educational pursuits at accredited U.S. institutions, ensuring that the legacy of community service and support continues. With criteria focusing on family connections to the Elks and a commitment to education, these awards promote opportunities for future generations to thrive and contribute to society.
Academic Scholarship Programs Education - Higher Education

Whataburger Family Foundation Scholarship Fund

San Antonio Area Foundation
Private
United States
Unspecified amount
The Whataburger Family Foundation Scholarship Fund, managed by the San Antonio Area Foundation, supports individuals pursuing higher education. It is open to U.S. citizens or legal residents with a minimum 2.5 GPA, who are employed or have family ties to Whataburger employees. This scholarship is available for various fields of study and can be applied to both full-time and part-time enrollment in accredited institutions across the USA. It aims to enhance educational opportunities and community growth.
Education - Higher Education Academic Scholarship Programs

Walter and Hannelore Schwindt Trust

San Antonio Area Foundation
Private
United States
Unspecified amount
The Walter and Hannelore Schwindt Trust, managed by the San Antonio Area Foundation, supports students pursuing degrees in various scientific and technical fields. Eligible applicants include current high school seniors and college students from specific Texas counties, with a minimum GPA requirement. This renewable scholarship covers tuition and living expenses for full-time students, emphasizing academic excellence and commitment to fields such as astronomy, medical research, and biochemistry.
Education - Higher Education Academic Scholarship Programs

Discovery of in vivo Chemical Probes for the Nervous System

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is set to release a Notice of Funding Opportunity (NOFO) aimed at advancing the discovery of in vivo chemical probes for brain targets. Collaborating institutes include the National Eye Institute (NEI), National Institute on Drug Abuse (NIDA), and National Institute of Mental Health (NIMH). The initiative seeks to foster research into small molecules and novel biological targets related to brain diseases, encouraging innovative projects and collaborations.
Neurological Diseases & Disorders

Grants for 501(c)(3) in South Carolina Highlights

Looking for grants for 501(c)(3) in South Carolina?


Read more about each grant below or start your 14-day free trial to see all grants for 501(c)(3) in South Carolina recommended for your specific programs.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grants for 501(c)(3) in South Carolina

Grant Availability

How common are grants in this category?

Common — grants in this category appear regularly across funding sources.

200+ Grants for 501(c)(3) in South Carolina grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

54 Grants for 501(c)(3) in South Carolina over $25K in average grant size

41 Grants for 501(c)(3) in South Carolina over $50K in average grant size

32 Grants for 501(c)(3) in South Carolina supporting general operating expenses

100+ Grants for 501(c)(3) in South Carolina supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

2,000+ Grants on Instrumentl focused on Human & Social Services

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for grants for 501(c)(3) in South Carolina?

Most grants are due in the first quarter.

Q1
28.9%
Q2
26.6%
Q3
24.1%
Q4
20.4%

Typical Funding Amounts

What's the typical grant amount funded for Grants for 501(c)(3) in South Carolina?

Grants are most commonly $15,000.

$500 $500 Min.
$15,000 $15 K Median
$530,911 $530.9 K Average
$40,331,313 $40.3 M Max.

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Grants for 501(c)(3) in South Carolina year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Grants for 501(c)(3) in South Carolina given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Grants for 501(c)(3) in South Carolina changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081