Best Large Grants for Nonprofit Organizations in South Carolina

The Etsy Uplift Fund, managed by Brooklyn Org, supports nonprofits that eliminate barriers to entrepreneurship for creators. By addressing challenges like lack of digital education, access to capital, and insufficient benefits, the Fund aims to foster equal opportunities in creative entrepreneurship. Customers can contribute by rounding up their purchases, with the collected funds directly supporting organizations that help creators build successful businesses. This initiative underscores Etsy's commitment to empowering diverse communities.

The DoW Rare Cancers Idea Development Award promotes innovative research ideas for rare cancers, encouraging applicants to provide preliminary data and exploratory aims. This funding opportunity, offered by the US DOD: U.S. Army Medical Command, seeks projects with the potential for high-impact findings that can significantly benefit the patient community. It aims to foster new avenues of investigation and support discovery-driven research in the field of rare cancers.

The 2026 Rare Cancers Research Program Resource and Community Development Award aims to enhance rare cancer research through improved resources and datasets. It addresses critical gaps in research resources, communication strategies, and data sharing infrastructures. Key features include engaging patient advocates throughout the research process and ensuring sustainability of community platforms. This funding opportunity emphasizes community building and the dissemination of findings to benefit scientific and patient communities alike.

The FY26 Joint Warfighter Medical Research Program's Military Medical Research and Development Award aims to fund the continuation of previous Department of War-funded research addressing high-priority medical needs for Service Members and Military Health System beneficiaries. It supports various projects, including late-stage preclinical studies and clinical research. Eligibility requires prior DOD funding, and a Clinical Research Option is available for studies involving human subjects or biological samples.

The AACAP Educational Outreach Program for General Psychiatry Residents offers a unique opportunity for residents to gain insights into child and adolescent psychiatry. Participants will network with mentors and peers, attend the 71st AACAP Annual Meeting from October 14-19, 2024, and receive a stipend of up to $1,200 post-meeting. This program prioritizes first-time applicants, ensuring a valuable experience in a supportive environment while expanding professional connections.

The Research With Activities Related to Diversity (ReWARD) program by the NIH aims to enhance research diversity and inclusion across the United States. It supports scientists contributing to Diversity, Equity, Inclusion, and Accessibility (DEIA) who lack current NIH funding. The program funds both scientific research and DEIA activities, addressing the needs of various NIH Institutes and Centers to foster a more diverse biomedical research landscape.

The Middle School Music Grant, offered by the Peter R Marsh Foundation, aims to enrich the musical education of public middle school music teachers across the U.S. By facilitating performances at senior facilities, the grant fosters emotional connections between students and seniors, while providing essential classroom equipment. Funds cover music supplies, instruments, and transportation, ensuring students have the resources to thrive musically and socially. This initiative not only enhances music education but also promotes community engagement and empathy.

The Academic Research Enhancement Award (AREA) supports small-scale research at institutions that receive limited NIH funding, emphasizing biomedical research for undergraduate students. This program aims to enhance the research environment and provide valuable experiences for students. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over four of the last seven years. This funding opportunity encourages investigator-initiated minimal risk clinical trials to advance NIH missions.

The NCI Pathway to Independence Award (K99/R00) supports talented postdoctoral researchers in transitioning to independent faculty positions. This program provides essential NCI research funding to facilitate the development of competitive, independent research careers. Applications are due by 5:00 PM local time of the applicant's organization, emphasizing the importance of timely submissions for prospective awardees.

The Rauschenberg Medical Emergency Grants, administered by the New York Foundation for the Arts, provide one-time funding up to $5,000 for artists facing unexpected medical emergencies. This program aims to alleviate financial burdens caused by medical costs, ensuring that artists can receive necessary care without delay. Eligible applicants must be practicing artists in visual arts, film, or choreography, and demonstrate financial need. This initiative supports artists of color, LGBTQ+ individuals, and those outside major coastal cities.

The Petco Foundation offers disaster relief support for animal welfare organizations affected by disasters. Eligible applicants include authorized members of IRS-designated 501c3 nonprofits, government agency representatives with operational insight, and invited for-profit entities focused on animal welfare. However, the foundation does not fund individuals, organizations outside the U.S., or those whose primary mission does not relate to animal welfare. This initiative aims to provide critical assistance during times of crisis.

The NHGRI's Analysis, Visualization, and Informatics Lab-space (AnVIL) program is set for a limited competition renewal to enhance a cloud-based platform that supports genomic research. With over 5 petabytes of data accessible to researchers, AnVIL fosters collaboration and innovation while adhering to FAIR principles. The renewed focus will include improved scalability, interoperability, and robust security measures. Additionally, training initiatives will ensure researchers maximize the potential of AnVIL's multimodal datasets. The funding opportunity is expected in 2027.

The Radiation Oncology-Biology Integration Network (ROBIN) Centers, funded by the National Cancer Institute (NCI), aims to enhance national radiation oncology infrastructure through collaborative research. This initiative supports studies on biological responses to radiation treatment in cancer patients, focusing on understanding tumor and tissue changes. By integrating various scientific disciplines and collecting comprehensive data, ROBIN intends to improve cancer care, optimize treatment strategies, and accelerate translational discoveries to enhance patient outcomes.

Who We Are

Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.

The AAAS Mass Media Science & Engineering Fellowship is a prestigious 10-week summer program designed for science, engineering, and mathematics students to work at media organizations across the U.S. This fellowship enhances public understanding of science by equipping fellows with skills to communicate complex scientific concepts effectively. Participants will receive an $8000 stipend and gain invaluable experience in journalism, fostering collaboration between scientists and media professionals to create engaging science stories for the public.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The Republic Services Community Grant Program supports local nonprofit organizations focused on neighborhood revitalization, safety, disaster relief, and social services. Eligible 501(c)(3) organizations can apply once annually through an online application process. The program emphasizes a non-discrimination policy, ensuring services are provided without bias. However, funding is not available for individuals, government entities, schools, or religious organizations. This initiative reflects Republic Services' commitment to community engagement and support.

The Aging Research Dissertation Awards aim to enhance diversity in the scientific research workforce focused on aging and related health conditions. This funding opportunity encourages applicants to submit Letters of Intent prior to full application deadlines. Key submission dates for standard and renewal applications span from February 2025 to October 2026, ensuring a wide array of research topics can be addressed.

The Make a SPLASH! Grant Contest invites municipal entities and non-profits in the U.S. to apply for the Inclusive Design Award. This award recognizes splash pads that prioritize inclusivity and accessibility. Winners will receive a customized Life Floor safety surface, valued at $50-65k, promoting community engagement and safety. With two opportunities to win, this initiative aims to enhance splash pad designs, ensuring they cater to all individuals. Join us in making splash pads safer and more accessible for everyone!

The Youth Programming Grant, offered by the Native American Agriculture Fund (NAAF), aims to support Native American farmers and ranchers through various projects. This grant focuses on providing essential business assistance, agricultural education, and advocacy services. By funding diverse initiatives, the NAAF seeks to promote the ongoing involvement of Native communities in agriculture, ensuring their sustainable growth and development within the sector.

The Land and Water Conservation Fund's Outdoor Recreation Legacy Partnership Program aims to enhance recreational opportunities in underserved communities through significant funding. Offering matching grants up to 50%, with awards ranging from $300,000 to $15,000,000, this program encourages applicants to connect with the Connecticut Department of Energy and Environmental Protection early in the application process for guidance. This initiative supports large-scale projects that improve access to recreational facilities.

The David B. Jones Foundation Grant supports educational, research, and charitable initiatives in paleontology within the United States. Established in 1998, it offers various funding types, including one-time, multiyear, and challenge grants, focusing on projects that promote the science of paleontology. Eligible applicants are 501(c)(3) organizations aligned with the foundation's mission, prioritizing programs that engage young fossil hunters and public education through museums. The foundation does not fund individual requests or religious organizations.

The Mark Foundation Emerging Leader Award supports innovative cancer research led by early career investigators. Aimed at high-impact, high-risk projects, this grant is available to those employed by U.S. or Canadian non-profit academic institutions. Eligible applicants must be within three to eight years of starting their independent faculty research appointment. This award emphasizes multi-year independent funding and is not intended as the main funding source for the laboratory, ensuring that diverse research efforts are encouraged.

The Disability Foundation, in partnership with The Dayton Foundation, invites proposals for grants aimed at supporting organizations providing direct services to individuals with disabilities. Eligible applicants include community-based nonprofits and academic institutions. Grants, capped at $10,000, can be used for various purposes such as enhancing service accessibility, purchasing necessary equipment, and expanding services. This initiative seeks to empower disabled individuals by ensuring they receive essential resources and support.

The Investigators in the Pathogenesis of Infectious Disease Grant Program, funded by the Burroughs Wellcome Fund, aims to support early-career assistant professors studying human infectious diseases. With a budget of $505,000 over five years, it encourages innovative research on the interplay between human systems and infectious agents, fostering multidisciplinary approaches to enhance our understanding of disease mechanisms and health maintenance.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders 

There remains a scientific gap in understanding of the role of anti-TFP Imediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Geographic Scope

Brazil, China, Europe, Israel, Japan, Saudi Arabia, South Korea, Turkey, USA

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The Alpha Omega Alpha/Pharos Poetry Award

To encourage students to write effective poetry. Winning poems are published in The Pharos.

The Award

Up to 5 poems will receive a $1,500 award. The winning entries will be published in The Pharos.