Best Private Grants for Nonprofits in South Carolina

The Sorenson Legacy Foundation Grant aims to improve lives through support for education, health care, community development, and innovation. Established by James and Beverley Sorenson, the foundation focuses on enhancing art education, medical technologies, and community assistance in Utah. It prioritizes projects that foster artistic growth, promote innovative solutions, and address health care challenges while aiding vulnerable populations. The foundation's commitment to enriching lives reflects a deep-rooted belief in the power of education and community engagement.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Therapeutic Giving program from Johnson & Johnson Innovative Medicine aims to support local and regional organizations focused on improving patient access to treatment and advancing health equity. Eligible applicants include 501(c)(3) nonprofit organizations, with funding preferences for programs that address significant healthcare disparities, mental health initiatives, and innovative solutions with measurable outcomes. The application period for local organizations runs from March 1 to May 31, while national organizations can apply in September.

The Laurens County Community Foundation (LCCF) Community Enrichment Grants Program aims to enhance the quality of life for Laurens County citizens. Grants are available for initiatives that support education, job training, and community health. Eligible projects may address issues like homelessness, teen pregnancy prevention, and addiction treatment. The program prioritizes proposals benefiting a larger population and excludes funding for salaries, political campaigns, and construction projects. Interested individuals and organizations are encouraged to apply.

The Doyle Undergraduate Fellowship, offered by New Hampshire Sea Grant, provides a unique opportunity for undergraduates to engage in marine resource projects while receiving mentorship and training. This paid fellowship supports students interested in marine-related research and education, with potential earnings of up to $5,000 over a 10-week summer period. By participating, fellows gain valuable insights into coastal and marine management, enhancing their skills and expanding their professional networks.

The Therapeutic Giving initiative by Johnson & Johnson focuses on funding programs in neuroscience aimed at enhancing patient access to treatments and promoting health equity. Nonprofit organizations classified as 501(c)(3) can apply for support from March 1 to May 31. The initiative emphasizes innovative, measurable programs in areas like Alzheimer’s disease and mental health, prioritizing those that address healthcare disparities and improve quality of life for affected individuals.

South Carolina Arts Commission

The mission of the South Carolina Arts Commission is to expand access to the arts and foster creativity for all South Carolinians.

For more than 50 years, the agency has worked to build a thriving arts environment that benefits all South Carolinians, regardless of their circumstances or where they live.

We help artists and arts providers offer unique arts experiences to residents and visitors. From free poetry readings and gallery crawls to sweetgrass basketry workshops and ticketed dance, music, or theatre performances, they create an environment that contributes to quality of life from three “corner” counties of Oconee, Horry, and Beaufort to the 43 arranged inside.

Since 1967, the SCAC has awarded more than $132 million in grants to artists, arts organizations, school districts, schools, and teachers!

Festivals Grants

Purpose

To provide support for a broad range of arts activities at festivals that take place in—and have an impact on—S.C. communities, increasing opportunities for public engagement and participation in arts and culture.

A festival is a day or period of celebration or gathering of people that:

• Happens in a condensed period of time (i.e., an annual celebration or anniversary or an organized series of concerts, plays, movies, or performances held in the same place).
• Has an easily identifiable or unifying theme or specified focus.

Restrictions

• The festival cannot span the duration of more than two (2) consecutive weekends (no more than 14 consecutive days).
• Seasonal series of presented works, as well as freestanding installations, productions or exhibitions, are ineligible activities for this program.
• Applicants may submit only one (1) application per deadline.

Requirements

• The festival must be held in South Carolina.
• The festival must have identifiable arts activities (visual, media, performing, literary, and/or folk and traditional arts).
• The festival must compensate visual, media, performing, literary, and/or folk and traditional artists.
• The festival must be open to the public and include some aspect of free arts programming.

Funding type: Reimbursement

Matching Requirements

1:1 (grantee:SCAC)

• Up to 50% of the grantee’s match may be through an in-kind donation of materials and/or contracted services.
• An example of “in-kind” is a contracted fee that is waived or discounted as a donation to your project.
• Another SCAC grant and/or federal funds may not be used to match your award.

Indirect Cost Limitation

No more than 10% of the total grant funds may be used for indirect costs (general overhead expenses not directly tied to the project). The remaining 90% must go toward direct costs, which are necessary to carry out the funded project.

• Examples of direct costs: Artist fees, program supplies, travel for project activities, and venue rental.
• Examples of indirect costs: Administrative salaries not directly working on the project, office rent, utilities, and general office supplies.

This ensures that most of the funding directly benefits the project while allowing some flexibility for necessary overhead costs.

Compliance with State and Federal Laws

All grant applicants must ensure their applications, proposed projects, and any related materials comply with all applicable federal, state, and local laws. This includes SC Code § 16-15-305 (2024), which prohibits the dissemination of obscene materials.

Obscene content is strictly prohibited in grant applications and any proposed project activities. Applications that include materials or activities determined to be obscene will not be reviewed or considered for funding.

No component of an SCAC-funded project, including those funded with SCAC funds and those funded with matching funds, can fall into this category. Failure to comply with these regulations may result in the termination of funding and other legal consequences.

We strongly encourage all applicants to carefully review the full legal text of SC Code § 16-15-305 (2024), to ensure their proposals are in full compliance.

The Therapeutic Giving: Oncology program by Johnson & Johnson focuses on funding initiatives that enhance patient access to treatments and services, promote health equity, and strengthen healthcare workforces. It supports programs that raise disease awareness, empower patients, and improve health systems with measurable outcomes. Eligible applicants include nonprofit organizations with 501(c)(3) status, emphasizing innovative programs addressing healthcare disparities and unmet needs.

The U.S. Healthcare Donations program by Amgen aims to support not-for-profit organizations in the healthcare sector. As a leading biotechnology company, Amgen provides funding for initiatives that improve science, technology, education, and public awareness on medical conditions. Organizations eligible for funding must be tax-exempt entities, focusing on genuine philanthropic efforts that align with Amgen's mission to enhance health outcomes and reduce the burden of diseases.

The Joseph J. Miller Foundation Grant supports diverse charitable initiatives for both Jewish and non-Jewish organizations in South Carolina. Established in 1973, this grant prioritizes local groups, especially those in Elloree, and focuses on areas including arts, education, health, and human services. Organizations must be 501(c)(3) exempt, with equal funding allocated to Jewish and non-Jewish entities. This commitment reflects a strong dedication to community development and support.

The Sundt Foundation, established in 1999, supports local communities by offering grants and volunteer opportunities for 501(c)(3) nonprofit organizations. Focused on youth development, hunger and nutrition, and veteran services, the Foundation prioritizes projects in regions such as the Southwest and Southeast United States. However, they do not fund requests exceeding $25,000 or support multi-year pledges, fundraising events, or political causes. Their mission continues to foster community connections and belonging.

The Entergy Charitable Foundation Grant focuses on supporting initiatives that foster thriving communities through education, poverty solutions, and environmental programs. The foundation prioritizes funding for 501(c)(3) organizations and similar entities. Key areas include education development, innovative poverty solutions, and environmental restoration efforts, such as coastal wetland preservation. Organizations are encouraged to apply at least three months before funding is needed, ensuring timely support for impactful community projects.

The Ron Goellner Conservation Fund Award, administered by the Cryptobranchid Interest Group, offers grants up to $2,000 for projects focused on the conservation of giant salamanders. This initiative supports innovative research, field conservation, and educational initiatives that aim to protect these species and their habitats. Open to all applicants, the fund prioritizes projects that demonstrate broad conservation impact and partnerships. Applications are automatically considered for two separate grants of up to $1,000 each.

South Carolina Arts Commission

The mission of the South Carolina Arts Commission is to expand access to the arts and foster creativity for all South Carolinians.

For more than 50 years, the agency has worked to build a thriving arts environment that benefits all South Carolinians, regardless of their circumstances or where they live.

We help artists and arts providers offer unique arts experiences to residents and visitors. From free poetry readings and gallery crawls to sweetgrass basketry workshops and ticketed dance, music, or theatre performances, they create an environment that contributes to quality of life from three “corner” counties of Oconee, Horry, and Beaufort to the 43 arranged inside.

Since 1967, the SCAC has awarded more than $132 million in grants to artists, arts organizations, school districts, schools, and teachers!

Cultural Districts Grants

Purpose

This grant supports a broad range of creative placemaking endeavors led by S.C. Cultural Districts, including—but not limited to—festivals, performances, workshops, and public art projects. All programming must be located within a Cultural District’s approved boundaries and align with its strategic plan.

Projects should:

• Integrate arts, culture, or design activities.
• Include non-arts partnership(s).
• Engage the public.
• Involve artists, designers, or culture bearers.

Each S.C. Cultural District may submit only one (1) application per cycle.

Grant funds must be used for actual project costs, defined as consumable and non-consumable items needed to complete the proposed project.

Funding type: Expense reimbursement.

Matching Requirements

1:2 (grantee:SCAC)

• A 1:2 match means that for each SCAC dollar granted, the grantee must match with $0.50 of their own funds. For example, if the total project cost is $15,000, the applicant may request $10,000 and must provide the remaining $5,000 from other sources.

• At least 50% of the applicant’s match must be cash.
• Funds may not be matched with another SCAC grant.

If you are hiring artists or teaching artists

For all grant-funded activities (including group lectures, demonstrations, performances, residencies, and short-term arts teaching experiences), the use of S.C. Arts Directory members is required for school and school district grantees and encouraged for grantees that are organizations.

Artists identified as Verified Teaching Artists on the S.C. Arts Directory have been additionally vetted by SCAC through the submission of sample lesson plans, recorded teaching samples, and letters of recommendation. For any grantee whose grant-funded activities are for K-12 student services, SCAC encourages the use of Verified Teaching Artists. Many school districts require the use of SCAC Verified Teaching Artists for classroom residencies. If working in a school environment, always check with both the individual school and the school district about policies related to hiring artists, arts organizations, and teaching artists. Learn more about the S.C. Arts Directory.

Indirect Cost Limitation

No more than 10% of the total grant funds may be used for indirect costs (general overhead expenses not directly tied to the project). The remaining 90% must go toward direct costs, which are necessary to carry out the funded project.

• Examples of direct costs: Artist fees, program supplies, travel for project activities, and venue rental.
• Examples of indirect costs: Administrative salaries not directly working on the project, office rent, utilities, and general office supplies.

This ensures that most of the funding directly benefits the project while allowing some flexibility for necessary overhead costs.

Compliance with State and Federal Laws

All grant applicants must ensure their applications, proposed projects, and any related materials comply with all applicable federal, state, and local laws. This includes SC Code § 16-15-305 (2024), which prohibits the dissemination of obscene materials.

Obscene content is strictly prohibited in grant applications and any proposed project activities. Applications that include materials or activities determined to be obscene will not be reviewed or considered for funding.

No component of an SCAC-funded project, including those funded with SCAC funds and those funded with matching funds, can fall into this category. Failure to comply with these regulations may result in the termination of funding and other legal consequences.

We strongly encourage all applicants to carefully review the full legal text of SC Code § 16-15-305 (2024), to ensure their proposals are in full compliance.

The Thornton S. Glide, Jr. and Katrina D. Glide Foundation provides grants to qualified 501(c)(3) organizations in California that focus on animal protection, land conservancy, agriculture, and civic endeavors. Established in 1995, the foundation prioritizes grants for specific capital acquisitions and does not support operational costs or direct aid to individuals. Emphasizing local impact, California-based organizations are favored over out-of-state counterparts.

The Arts in Rural Places Grant, offered by South Arts, aims to enhance access to the arts in rural and isolated communities across nine southern states. Grants of up to $3,000 support public activities featuring Southern artists, requiring a dollar-for-dollar cash match. Eligible organizations must host at least two public events and engage a professional artist, promoting cultural engagement and artistic expression within these communities.

Urban Forestry Grants

Eligible Projects for this Funding Opportunity

The intent of this funding is to assist state, local, and tribal governments in areas impacted by hurricanes and natural disasters in 2022, 2023, and 2024 by improving mitigating post-storm threats to ecosystem functionality and providing technical assistance for rural and community forest restoration. All projects and purchases must be shown in each proposal to have a direct positive impact on the recovery of the affected areas. Proposal narratives must explicitly describe how activities will assist in the recovery in impacted areas. SCFC will prioritize funding for projects affected by Hurricane Helene. SCFC will make subawards as described below to FEMA disaster declared counties/communities in South Carolina under this supplemental funding opportunity.

The Housing Justice Program Fellowship, offered by Equal Justice Works, addresses the urgent need for legal assistance among low-income individuals facing housing instability in Virginia, South Carolina, and Maryland. This two-year fellowship provides legal and organizational training, networking opportunities, and essential support for fellows dedicated to combating eviction and promoting housing justice. Ideal candidates possess strong communication skills and a commitment to community advocacy, making a significant impact in the lives of those at risk of displacement.

The State of South Carolina is an entitlement state, as designated by the U.S. Department of Housing and Urban Development HUD, and receives federal formula funding to address housing and community development needs statewide. 

The Emergency Solutions Grant (ESG) Program addresses the need for emergency shelter by funding shelters who provide services outlined by HUD to those who are currently homeless. The State Office of Economic Opportunity works closely with all four regional CoCs to identify needs and direct funds for emergency shelter services. 

The ESG program is a competitive grant issued each year to community-based shelters and traditional housing facilities, non-profit organizations that provide housing and counseling assistance to the state's homeless population and to those at-risk of becoming homeless.

The Maine Cancer Foundation is seeking proposals for cancer screening initiatives aimed at early detection and prevention. This RFP focuses on screenings for breast, cervical, colorectal, lung, prostate, and skin cancers. Proposals should align with evidence-based practices endorsed by the CDC and U.S. Preventive Services Task Force. Interested applicants are encouraged to consult with MCF prior to submission to discuss project concepts and receive feedback on draft applications.

The Westinghouse Charitable Giving Program aims to strengthen community ties by providing financial support in key areas such as education focused on STEM, environmental sustainability, and community safety. This program welcomes applications from eligible organizations that meet specific grant criteria, including being tax-exempt and located within 50 miles of a Westinghouse site. The initiative underscores Westinghouse's commitment to advancing education, promoting environmental stewardship, and enhancing community well-being.

The WKKF Grant, offered by the W.K. Kellogg Foundation, is dedicated to fostering a future where every child and family thrives. With a focus on nurturing early education, accessible healthcare, and equitable food systems, this grant supports initiatives that empower communities across the U.S. and parts of Mexico and Haiti. Organizations meeting IRS regulations and being legal entities, particularly 501(c)(3) nonprofits, are encouraged to apply for funding to create lasting impacts in their communities.

The NACD Technical Assistance Grants program, in partnership with NRCS, has been enhancing conservation district support since 2018. By funding staff hires, it aims to improve service for agricultural producers and address conservation workload challenges. The initiative focuses on outreach, education, and civic engagement to empower local communities, promote sustainability, and support historically underserved producers in implementing conservation practices, thereby fostering both individual and community resilience.

Lilly Foundation

To extend Lilly’s charitable reach and impact, the Eli Lilly and Company Foundation (Lilly Foundation) was established in 1968 and is supported by donations from Eli Lilly and Company.

The Foundation is a tax-exempt, private foundation supporting programs that align with its philanthropic priorities.

Grantmaking Approach

The Lilly Foundation’s work is guided by a charitable vision of a world where every person has an opportunity to live their healthiest life. Through grantmaking focused on Lilly Foundation’s charitable vision, grants can serve as a catalyst for closing gaps and empowering individuals and communities to thrive.

All proposals should demonstrate clear alignment with at least one focus area and include charitable outcomes that are measurable and consistent with the Foundation’s long-term charitable goals.

Global Health, K-12 STEM Education and Economic Mobility Grant

Focus Areas

Global Health

Lilly Foundation, through its charitable grants, aims to support permissible charitable efforts to improve access to quality healthcare for resource-limited communities in low- and lower-middleincome countries (L/LMICs) and in the United States. Strengthening access to care is essential for enhancing community well-being and supporting economic stability in resource-limited settings.

The Global Health focus area aims to close gaps in quality healthcare by supporting charitable solutions that improve access, bring care closer to where people live, and address the high burden of non-communicable diseases (NCDs) in resource-limited settings. To the extent permissible, the Foundation prioritizes charitable efforts related to cardiometabolic health in resource-limited settings.

K-12 STEM Education

The K-12 STEM Education focus area aims to close the gaps for students from low-income communities by supporting programs that foster new pathways and pipelines to STEM education through focused K-12 efforts, concentrating on the critical middle school years. The Foundation’s K-12 STEM Education grants are focused on initiatives that benefit Marion County, Indiana.

Economic Mobility

The Economic Mobility focus area supports charitable and educational programs that strengthen workforce readiness, postsecondary and skills-based educational pathways, and housing stability to promote long-term prosperity. This support is focused on Marion County, Indiana, with the goal of improving economic opportunity for low-income communities and advancing community well-being.

The Wellness Within Reach initiative aims to bring high-quality, face-to-face healthcare directly to rural South Carolina communities through mobile units, crisis response teams, and community-based care sites This grant opportunity seeks proposals from eligible organizations to strengthen South Carolina’s mobile crisis response and expand community care sites.

The Kosciuszko Foundation offers Tuition Scholarships for American students of Polish descent pursuing graduate studies in the U.S. Scholarships can provide up to $12,000 for full-time studies, including master's and Ph.D. programs. Eligible applicants must be U.S. citizens or legal residents with Polish heritage and maintain a minimum GPA of 3.0. This program aims to foster educational exchanges and cultural understanding between the U.S. and Poland, supporting various fields of study.

QuikTrip is dedicated to supporting at-risk youth and early childhood education through strategic community investments. By donating 5% of annual net profits to qualified non-profits, QuikTrip aims to empower individuals and break the cycle of poverty. The company partners with organizations providing educational opportunities, ensuring that all youth, regardless of their backgrounds, can thrive as independent citizens. This initiative highlights QuikTrip's commitment to making a measurable impact in the communities where its employees live and work.