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Best St. Clair County Grants for Nonprofits in Missouri

Looking for grants for 501(c)(3) nonprofit organizations working in St. Clair County, Missouri? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$3.38B

Total funding

$5K

Median grant

9,000+ grants
$3.38B total
$5K median

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9,190 Results based on applied filters

First Responders Outreach (FRO) Grant

Gary Sinise Foundation
Private
United States
Unspecified amount
The First Responders Outreach (FRO) Grant, provided by the Gary Sinise Foundation, supports essential resources for firefighters, police, and EMTs. This grant specifically targets First Responder Departments, allowing one application per year focused on equipment and training. It excludes funding for building costs and weaponry. This initiative aims to enhance the safety and preparedness of those who protect our communities during emergencies, ensuring they have the necessary tools and training to perform their vital roles effectively.
First Responders

9.11 Promise Run Scholarships

9.11 Promise
Association/Society
United States
US $5,000 - US $15,000
The 9.11 Promise Run Scholarships provide financial support to children of first responders and military personnel who have been killed or injured. Established in 2019, these scholarships range from $5,000 to $15,000 and can be applied toward trade school or college tuition. Eligible applicants must be under 25 years old and maintain a minimum GPA of 2.0. Awards are issued directly to accredited institutions and can be renewed for up to six years, ensuring continued support for eligible students.
Academic Scholarship Programs College Success / Persistence

Thoma Foundation Special Project Funding Grant

Carl And Marilynn Thoma Foundation
Private
United States
Unspecified amount
The Carl and Marilynn Thoma Foundation offers Special Project Funding to support innovative initiatives in the arts, particularly in under-resourced areas. This grant encourages collaborative projects that enhance community engagement and education, focusing on art exhibitions and scholarships in the greater Texas Panhandle. By fostering leadership and creativity, the Foundation aims to empower individuals and organizations to make a lasting impact in the fields of art and art history.
Fine Art Visual Arts Art Education +7 more

Kathryn Cramer Early Career Research Development Award

Ao North America Inc
Private
Canada, United States
Up to US $35,000
The Kathryn Cramer Early Career Research Development Award provides essential start-up funding for orthopedic trauma surgeons in the U.S. and Canada, who have completed their fellowship within the last five years. This award aims to support innovative research projects that can be accomplished within two years, fostering professional development and collaboration among surgeons. Applicants must be members of AO Trauma and demonstrate early success in their research endeavors.
Orthopedics Medical Education & Professional Training

Henry Hanff Fellowship Award

Ao North America Inc
Private
Europe, North America
Up to US $5,900
The Henry Hanff Fellowship Award offers a unique opportunity for practicing North American trauma surgeons to enhance their skills through a short-term fellowship at a trauma clinic in North America or Europe. Sponsored by AO North America, the fellowship lasts four to eight weeks and covers airfare and a stipend for living expenses, with a total award not exceeding $5,900. Participants must submit a report on their experience for publication, enhancing professional development and collaboration.
Orthopedics Medical Education & Professional Training

AO Spine NA: Young Investigator Research Grant Award

Ao North America Inc
Private
North America
US $20,000
The AO Spine NA Young Investigator Research Grant Award supports early-career surgeons and researchers focusing on clinically relevant spinal or spinal cord research. With funding of $20,000, this initiative encourages new investigators by providing essential start-up capital. Successful applicants are required to present their findings at the Annual AO Spine North America Fellows Forum and submit progress and final reports detailing their research outcomes. This grant aims to foster innovation and excellence in spinal care.
Spinal Cord Injuries Medical Education & Professional Training Orthopedics

Frederic C. Collin Trust Grant

COLLIN FREDERIC C TUW
Private
United States
US $2,000 - US $3,800
The Frederic C. Collin Trust Grant supports 501(c)(3) organizations in promoting polo and tennis, especially among youth. Established under Frederic C. Collin's will, it offers grants ranging from $2,000 to $3,800, with an annual total giving of approximately $9,000. Applications are accepted year-round for consideration during the annual grant meeting. This initiative aims to enhance participation in these sports, fostering talent and interest among young players.
Tennis Equestrian Sports

Opportunities for Collaborative Research at the NIH Clinical Center

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Opportunities for Collaborative Research at the NIH Clinical Center aims to foster high-quality translational research partnerships between NIH intramural and extramural investigators. This program supports projects that bridge basic biological discoveries with clinical applications, ultimately enhancing patient-centric research. By facilitating collaborations, the program seeks to accelerate scientific advancements leading to improved health outcomes through innovative therapeutic interventions and diagnostic strategies.
Biology Health & Medicine

David and Jacquie Clark Family Fund Grant

David And Jacquie Clark Family Fund
Private
United States
Unspecified amount
The David and Jacquie Clark Family Fund, established in 2017, aims to support individuals with special needs and their families through grants to nonprofits. With a focus on Ohio organizations, the fund seeks to ensure equitable opportunities for these individuals, fostering their success and well-being. Since its inception, the fund has provided assistance to over 30 nonprofits across the U.S., enhancing programs that promote learning and growth outside traditional educational settings.
Intellectual / Developmental Disabilities Academic Success & Enrichment

Ruth Danley and William Enoch Moore Charitable Fund Grant

The Ruth Danley And William Enoch Moore Fund
Private
United States
Approximately US $77,000
The Ruth Danley and William Enoch Moore Charitable Fund Grant is a private foundation based in Pittsburgh, established in 1992. It focuses on philanthropy, specifically supporting K-12 education for Native American children living on reservations. The foundation directs its grants primarily to regions preferred by donors, including several states in the Northeast and Midwest, aiming to improve educational opportunities and foster community development in underserved populations.
Education - K through 12 Native American Services Educational Access & Equity

Andrea-Mennen Family Foundation Grant

The Andrea-Mennen Family Foundation
Private
United States
Unspecified amount
The Andrea-Mennen Family Foundation Grant aims to enhance the quality of life for children and young adults facing mental and physical challenges. By supporting registered charitable organizations that align with its mission, the foundation seeks to ensure that 100% of grant funds directly benefit those in need within the US. Emphasizing immediate results and proven success, the foundation is dedicated to making a positive impact in the lives of future generations.
Youth Services Children’s Mental Health Child Welfare Services +5 more

The James Paul Sutton Medical Research Fund Grant

James Paul Sutton Medical
Private
United States
Approximately US $15,000
The James Paul Sutton Medical Research Fund Grant supports non-profit organizations engaged in cancer and medical research, established through a trust by the Sutton family. Eligible organizations must be 501(c)(3) exempt. Preference is given to cancer research initiatives, while grants are not available for individuals, political groups, or for-profit entities. This fund aims to sustain medical research efforts for the long term, continuing the legacy of the Sutton family.
Cancer / Oncology

Robert J. Keown Trust Grant

KEOWN ROBERT J TUW
Private
United States
US $10,000 - US $20,000
The Robert J. Keown Trust, established in 1934, provides financial assistance to needy Christians through grants to charitable organizations. Managed by Wells Fargo Bank N.A., the trust focuses on supporting organizations that benefit residents of Los Angeles County. Eligible organizations must be 501(c)(3) exempt. Preference is given to requests aiding needy Christians and elderly women. The trust awards an average of four grants per year, fostering community support and outreach.
Senior Services Basic Human Needs Christianity +2 more

St. Baldrick’s Foundation Summer Fellowship Award

St Baldricks Foundation Inc
Private
United States
US $5,000
The St. Baldrick’s Foundation Summer Fellowship Award provides funding for undergraduate, graduate, or medical students to gain hands-on experience in pediatric oncology. With a stipend of $5,000 awarded to the mentor's institution, this fellowship supports the next generation of researchers dedicated to finding cures for childhood cancers. Since its inception, the foundation has mobilized volunteers through various fundraising events, fostering a community committed to transforming lives and advancing cancer research.
Academic Success & Enrichment After School / Summer Educational Programs College Success / Persistence

St. Baldrick's Foundation Scholar (Career Development) Award

St Baldricks Foundation Inc
Private
United States
Up to US $330,000
The St. Baldrick's Foundation Scholar (Career Development) Award supports early-career researchers dedicated to childhood cancer research. This three-year award, which can be extended for two additional years based on progress, provides up to $110,000 per year. Founded in 2000, the foundation has mobilized volunteers worldwide to raise funds through head-shaving events and various activities, all aimed at finding cures and improving survivors' lives.
Children’s Health & Pediatrics Pediatric Cancers

St. Baldrick’s Foundation Research Grant Award

St Baldricks Foundation Inc
Private
United States
Up to US $200,000
The St. Baldrick’s Foundation Research Grant Award supports innovative research aimed at curing childhood cancers. With funding of $100,000 per year for two years, this grant is designed for hypothesis-driven projects that can be laboratory, clinical, or epidemiological in nature. Established through community-driven fundraising events, the foundation empowers volunteers and donors to make a significant impact in the fight against cancer, ensuring a brighter future for young survivors.
Pediatric Cancers

St. Baldrick’s Foundation Fellowship Award

St Baldricks Foundation Inc
Private
United States
Up to US $195,000
The St. Baldrick’s Foundation Fellowship Award supports pediatric oncology training through a two-year fellowship, with a potential third year based on need and achievements. This initiative, powered by community fundraising events, aims to advance research for childhood cancer cures. The award provides a salary capped at $97,500 per year, covering salary and benefits for fellows. This fellowship not only fosters professional growth but also contributes significantly to the fight against childhood cancers.
Pediatric Cancers

Numotion Foundation Grants

Numotion Foundation
Private
United States
US $500 - US $10,000
The Numotion Foundation Grants aim to enhance the lives of individuals with mobility disabilities by supporting IRS-designated 501(c)(3) nonprofit organizations. By fostering partnerships with various charities, including national and local organizations, the foundation raises awareness and funds for necessary research and support services. Contributions are made for each new wheelchair sold, ensuring a coordinated approach to charitable giving while prioritizing programs that specifically assist those with mobility-related challenges.
Disability Care & Services Children With Disabilities Physical Disabilities

Tipgoomoogus Memorial Trust Grant

1992 Tipgoomoogus Memorial Trust
Private
United States
US $5,000 - US $10,000
The Tipgoomoogus Memorial Trust Grant supports organizations dedicated to the care and comfort of small household pets, including dogs, cats, and birds. Founded by Thomas and Ellen Fallon, the trust primarily funds New Jersey-based charities that qualify as 501(c)(3) organizations. Applications are accepted year-round, with a submission deadline of April 30 for annual review. The foundation prefers to assist animal shelters and dog pounds, while excluding funding for salaries or animals raised for commercial or research purposes.
Animal Welfare - Domestic Animals & Pets

Harry Kramer Memorial Fund Grant

Harry Kramer Memorial Fund
Private
Israel, United States
US $10,000 - US $25,000
The Harry Kramer Memorial Fund Grant supports U.S. charitable organizations that assist individuals and institutions in Israel, focusing on welfare, healthcare for the sick and aged, and education in South Florida. Founded by Harry A. Kramer, a successful entrepreneur and veteran, the fund reflects his deep commitment to charitable causes. Organizations must qualify under Section 501(c)(3) and meet specific eligibility criteria to apply for funding, ensuring that aid reaches those in need.
Jewish Culture Senior Services Religion & Spirituality +4 more

Downing-Nix Trust Grant

Frances Downing Nix 1013002741
Private
United States
US $6,000 - US $12,000
The Downing-Nix Trust Grant provides funding for organizations engaged in research on muscular dystrophy, maintaining treatment wards in Atlanta hospitals, offering veterinary medicine scholarships, and supporting shelters for small animals. Organizations must qualify as 501(c)(3) charities. Applications are accepted year-round, but submissions by April 15 are required for annual meeting reviews. Priority may be given to hospitals and veterinary schools within Atlanta, GA.
Muscular Dystrophy Health Facilities & Clinics Veterinary Science & Services +2 more

Howe Foundation Grant

Howe Foundation 45871100
Private
United States
Approximately US $5,000
The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.
Education Health & Medicine Wildlife Management +1 more

Hunger to Health Collaboratory (H2HC) 2026 Prizes for Innovation

Newmans Own Foundation
Corporate
United States
Up to US $100,000
The Hunger to Health Collaboratory (H2HC) 2025 Prizes for Innovation aim to enhance health equity for youth through innovative funding in three categories: Food and Nutrition Policy, Nutrition Education & School Food, and Indigenous Food Justice. Supported by Newman’s Own Foundation, these prizes include $100K grants for policy work and $25K grants for education and justice initiatives. Winners will participate in the H2HC Fall Summit in Boston, fostering collaborative solutions to food challenges.
Food Access & Hunger Youth Services Indigenous Sovereignty & Rights +2 more

George William Groh Trust Grant

Groh George W Tr FBO Med Research
Private
United States
US $11,500
The George William Groh Trust Grant supports medical research initiatives by providing funding to organizations that qualify as exempt under Section 501(c)(3) of the Internal Revenue Code. Applications are accepted year-round, with a deadline of May 1 for consideration at the annual grant meeting. The foundation aims to enhance medical research efforts and contribute to advancements in healthcare.
Health & Medicine

Aarón Sánchez Impact Fund - Human Service Grant

Emeril Lagasse Foundation
Private
United States
Up to US $20,000
The Aarón Sánchez Impact Fund, a program of the Emeril Lagasse Foundation, aims to uplift Latino youth through food. This grant offers up to $20,000 to non-profit organizations focused on nutrition education and food access for youth aged 0-18. Eligible applicants must have 501c3 status and serve a community where at least 60% of the population is Latino. This fund is by invitation only, encouraging innovative projects that align with its mission.
Hispanic and Latino Services

Giving Branch Donations

Giving Branch Foundation
Private
Arkansas, Illinois +7 more
Up to US $5,000
The Giving Branch Foundation, fully funded by Flat Branch Mortgage, Inc. employees, aims to support local communities through donations. By distributing funds to individuals facing hardships such as unexpected medical bills or disaster recovery, the foundation strives to uplift those in need. Grants are available for various eligible hardships, ensuring financial assistance reaches those who require immediate support. The mission is to give back to communities that have long supported the foundation's efforts.
Basic Human Needs Emergency Medical Care & Services All fields of work +1 more

Veteran Grant

The Hanger Charitable Foundation
Corporate
United States
Up to US $20,000
The Hanger Foundation's Veteran Grant aims to empower veterans facing physical challenges by providing support for rehabilitation services and athletic programs. This grant seeks to positively impact veterans' lives, particularly those with limb differences, through community engagement and employee involvement in charitable efforts. With a focus on 501(c)(3) organizations, the foundation invests in projects that address trauma and promote social activities, ensuring that veterans receive the assistance they need.
Military & Veterans Services Medical Rehabilitation

St. Clair County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all St. Clair County grants recommended for your specific programs in Missouri.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in Missouri

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in St. Clair County Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the St. Clair County Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for St. Clair County Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

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