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Best St. Louis city Grants for Nonprofits in Missouri

Discover active funding opportunities in St. Louis city Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in St. Louis County, Jackson County, and St. Charles County.

9,000+

Available grants

$3.38B

Total funding

$5K

Median grant

9,000+ grants
$3.38B total
$5K median

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9,232 Results based on applied filters

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) (363939)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $80,000
The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.
Health & Medicine Epidemiology & Public Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program

US DOJ: OJP Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $645,000
The BJA FY 2026 Emmett Till Unsolved Civil Rights Crimes Act Program aims to assist state, local, and tribal law enforcement agencies in investigating and prosecuting civil rights offenses that resulted in death before December 31, 1979. This funding opportunity is part of the DOJ's broader commitment to enhance public safety, protect civil rights, and ensure justice for victims of violent crime. Applications are due on November 20, 2026.
Social Justice / Human Rights Crime & Justice Community / Public Safety +2 more

F26AS00023 FY2026 Prescott Marine Mammal Rescue and Response Grant Program

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The F26AS00023 FY2026 Prescott Marine Mammal Rescue and Response Grant Program offers crucial financial support for marine mammal rescue efforts. This initiative aims to assist eligible participants in the recovery and treatment of stranded marine mammals, provide emergency response to stranding events, and enhance scientific research on marine mammal health. The program prioritizes applications that effectively address species-specific needs and bolster the capacity of stranding networks, ensuring the welfare of marine wildlife under the management of the U.S. Fish and Wildlife Service.
Marine / Ocean Conservation Wildlife Health

Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIH is set to release a Notice of Funding Opportunity for early to definitive clinical trials across various biomedical fields. This initiative focuses on trials evaluating drugs, devices, and interventions that align with NIH's mission. Utilizing the R61/R33 funding mechanism, projects can span up to 7 years, supporting both planning and trial phases. Interested investigators are encouraged to prepare collaborative proposals, although applications are not currently being solicited.
Health & Medicine Health Care Access & Delivery

Visa Foundation U.S. Small Business Growth and Innovation Program

Rockefeller Philanthropy Advisors Inc
Private
U.S. Territories, United States
US $100,000 - US $250,000

Across the United States, small and micro businesses (SMBs) play a critical role in driving economic opportunity, job creation, and community prosperity. Yet many entrepreneurs continue to face challenges accessing the training, resources, and support needed to grow and remain competitive in an evolving economy. To help address these needs, Visa Foundation is committing $2M to launch an open-call grant program that will support nonprofit Entrepreneurial Support Organizations (ESOs) that provide direct services to SMBs. Through this program, Visa Foundation aims to strengthen the capacity of high-impact organizations that help small businesses build greater resilience, expand economic opportunity, and contribute to thriving local economies. 

Business Development Entrepreneurship

Mensa Foundation Prize

Mensa Education And Research Foundation
Private
Countries
US $10,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Mensa Foundation Prize

The Mensa Foundation Prize celebrates exceptional achievements that redefine our understanding of intelligence and creativity.

Awarded biennially, this distinguished honor highlights transformative scientific discoveries that elevate the understanding of intelligence.

Details

One of the most prestigious honors in the field, the Mensa Foundation Prize highlights exceptional contributions that elevate the understanding of intelligence.

Award Components

Criteria for Entry

Neuroscience

Mensa Foundation: Lifetime Achievement Award

Mensa Education And Research Foundation
Private
Countries
US $2,500

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Lifetime Achievement Award

The Lifetime Achievement Award recognizes individuals whose lifelong contributions have profoundly advanced the understanding, support, and application of intelligence.

Details

This prestigious honor highlights transformative contributions that have reshaped how intelligence is studied, taught, and applied in real-world settings.

Award Components

Recipients of the Lifetime Achievement Award receive:

  • Permanent recognition as a distinguished leader in the field of intelligence.
  • A $2,500 monetary award in honor of their exceptional achievements.
  • A commemorative trophy celebrating their lasting impact on the field.
Education Neuroscience

Mensa Foundation Gifted Education Fellowship

Mensa Education And Research Foundation
Private
United States
US $5,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Fellowships

The Mensa Foundation Fellowship program empowers exceptional individuals committed to advancing the application of intelligence in their respective fields.

Details

Our current fellowship, the Gifted Education Fellowship, is designed to empower educators pursuing graduate studies in gifted education or closely related fields, enabling them to make a transformative impact in their classrooms and communities. The fellowship supports both doctoral and non-doctoral students, with awards and renewal terms tailored to each track.

Neuroscience Teacher Development & Training Education - Higher Education +1 more

Mensa Foundation: Dissertation Mini-Grant

Mensa Education And Research Foundation
Private
Countries
US $2,500

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Dissertation Mini-Grant

The Mensa Foundation empowers the next generation of researchers through its Dissertation Mini-Grant program.

Designed to support advanced doctoral students, this grant funds innovative studies that broaden our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Mensa Foundation Dissertation Mini-Grant provides $2,500 to advanced doctoral students conducting research on intelligence and gifted education. By funding innovative studies, the grant promotes research that addresses the complexities of intelligence, creativity, and related fields.

Grant Components

Education - Higher Education Neuroscience Humanities & Social Science +4 more

Early Career Mini-Grant

Mensa Education And Research Foundation
Private
Countries
US $2,500

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Grants & Fellowships

Early Career Mini-Grant

The Mensa Foundation empowers emerging researchers through its Early Career Mini-Grant program.

Designed to support post-doctoral researchers and early career faculty, this grant funds innovative studies that advance our understanding of intelligence, creativity, gifted education, and related fields.

Details

The Early Career Mini-Grant provides $2,500 to support post-doctoral researchers and faculty within five years of completing their doctoral degree. This grant is intended to promote groundbreaking studies that advance our understanding of intelligence and its applications in education and beyond.

Grant Components

Neuroscience Education Academic Success & Enrichment

Mensa Foundation: Copper Black Award

Mensa Education And Research Foundation
Private
Countries
US $1,000

About

Founded in 1971, the Mensa Foundation was established by members of American Mensa to extend the organization’s impact. While connected by a shared purpose, the Foundation operates independently, guided by its own Board of Trustees, strategic plan, and initiatives.

Awards

Cooper Black Award for Creativity

The Copper Black Award for Creative Achievement honors Mensa members whose innovative solutions and practical creativity have brought meaningful benefits to the world.

Details

The Copper Black Award annually recognizes Mensa International members who have demonstrated a specific creative achievement with practical value. This award honors innovations that have been implemented, at least in part, to benefit others.

Award Components

Humanities & Social Science STEM / STEAM Education

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $5,000 - US $10,000,000
The FY 2027 Continuation of Solicitation invites applications to support various program areas, including Advanced Scientific Computing, Basic Energy Sciences, Fusion Energy Sciences, and more. This annual open solicitation from the Department of Energy (DOE) allows research proposals throughout the fiscal year. Applications must align with SC's mission and can be submitted until September 30, 2027, or until a new solicitation is issued. Detailed submission processes are outlined in 10 C.F.R. part 605.
Energy Science Physics +1 more

Region 4 Small Business Transportation Technical Assistance Center (SBTTAC)

US Department of Transportation: Office of the Secretary (OST) Administration Secretariate
Federal Government
Alabama, Arkansas +7 more
Up to US $250,143
The Region 4 Small Business Transportation Technical Assistance Center (SBTTAC) aims to empower small businesses by providing essential technical assistance and business development support. Funded by the U.S. Department of Transportation, this initiative will facilitate access to capital resources, connect businesses with key transportation agencies, and ensure compliance with regulatory standards. The program is dedicated to minimizing barriers for small enterprises while fostering a robust support system in the transportation sector.
Entrepreneurship Economic Services & Development Business Development +1 more

Dairy Business Innovation Initiatives Program (DBI) Fiscal Year 2026

USDA: Agricultural Marketing Service (AMS)
Federal Government
United States
US $2,300,000 - US $3,450,000
The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.
Agriculture Agricultural Economics Business Development

WATER RESOURCES RESEARCH ACT PROGRAM NATIONAL COMPETITIVE GRANTS FY2026 (104g General)

US Department of the Interior: Geological Survey (USGS)
Federal Government
American Samoa, Guam +5 more
Up to US $120,000
The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.
Hydrology Freshwater Conservation Environmental Policy

Fiscal Year 2026 Wildlife Crossings Pilot Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.
Land / Habitat Conservation Community / Public Safety Wildlife Health +1 more

The Science, Mathematics and Research for Transformation (SMART) Scholarship for Service Program Cooperative Agreement

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $1,300,000,000
The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.
Education - Higher Education Workforce Preparation & Job Readiness STEM / STEAM Education

Water Safety and Security Act Project Grant

Missouri Department of Natural Resources
State/Local Government
Missouri
Up to US $15,000

Missouri Department of Natural Resources

Missouri’s air, land and water resources play an important role in our health and are essential to the environmental and economic vitality of our state. The department aspires to help Missouri citizens thrive by advancing environmental and economic sustainability. The department provides a range of services to help Missouri citizens, communities and businesses in these efforts. The department also provides opportunities to learn more about Missouri’s natural and cultural history at our state parks and historic sites.

Our Mission: We serve as stewards of our natural resources to benefit Missourians.

Water Safety and Security Act Project Grant

The Missouri Water Safety and Security Act, found in Missouri Revised Statutes section 640.144, RSMo, requires certain community public water systems to develop valve and fire hydrant inspection programs. The Act also requires systems to develop an accurate map identifying shut-off valve and hydrant locations using a geographic information system (GIS) or an alternative physical mapping system and create a hydrant inspection program.

Section 1452(g) and (k) of the federal Safe Drinking Water Act authorizes the Missouri Department of Natural Resources to distribute part of the Drinking Water State Revolving Fund (DWSRF) to public water systems to improve system capacity, promote asset management and maintain compliance with federal and state drinking water laws. Through this grant program, the department provides financial assistance to eligible community public water systems to develop accurate maps that satisfy the requirements of the Missouri Water Safety and Security Act.

Eligible Projects and Costs

Eligible projects are limited to contractual agreements to develop valve and hydrant inspection programs and accurate valve and hydrant maps that include all shut-off valve and hydrant locations throughout the applying water system’s distribution system and to satisfy the requirements of Section 640.144, RSMo.

A finalized valve and hydrant inspection program plan and/ or a map accurately depicting the locations of all system shut-off valves and hydrants must be provided to the department for a project to be considered complete. Reimbursement for pre-approved project-related costs is only issued following completion of awarded projects and submission of a finalized map to the department.

Award Amounts and Match

Funding is awarded on a first-come, first-served basis after the priority application period. Matching funds are not required, but may contribute to project selection and ranking according to the priority point criteria described in section 4 of the grant application form.

Sanitation & Clean Drinking Water Water Resource Management

Rehabilitation Research and Training Center (RRTC): National Research Center for Parents with Disabilities (363975)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $920,000 - US $925,000
The Rehabilitation Research and Training Center (RRTC) focuses on enhancing the lives of parents with disabilities through research, training, and technical assistance. This initiative aims to develop evidence-based services and supports that empower parents in their caregiving roles. Funded by the US HHS: Administration for Community Living (ACL), the project spans 60 months with a commitment to fostering inclusive environments for families. The RRTC will explore innovative interventions and technologies to better support these parents in their daily challenges.
Disability Care & Services Family Services

Rehabilitation Engineering Research Center on Technologies for People Who are Blind or have Low Vision

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $970,000 - US $975,000
The Rehabilitation Engineering Research Center aims to enhance services for individuals who are blind or have low vision through innovative technology development. This initiative focuses on overcoming rehabilitation challenges and environmental barriers, promoting independence and community living. A grant of five years will support ongoing research efforts, ensuring advancements in assistive technologies that empower the target population. The project aligns with the Rehabilitation Act's goals, emphasizing the importance of accessibility and inclusion.
Disability Care & Services Medical Rehabilitation Emerging Technology Development

Center on Knowledge Translation for Disability and Rehabilitation Research

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $795,000 - US $800,000
The Center on Knowledge Translation for Disability and Rehabilitation Research (KTDRR Center) aims to enhance the use of relevant disability and rehabilitation research through effective knowledge translation. Serving as a key resource for NIDILRR grantees and the general public, the KTDRR Center's initiatives will support high-quality research dissemination. The project spans 60 months, including five 12-month budget periods, ensuring ongoing support for researchers and stakeholders in the field.
Disability Care & Services Medical Rehabilitation

Burn Injury Model System Centers

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $560,000 - US $640,000
The Burn Injury Model System Centers aim to enhance burn rehabilitation through innovative research. These centers must create knowledge to improve the health, community engagement, and employment outcomes for individuals affected by burn injuries. Funded by US HHS's Administration for Community Living, grants support site-specific and collaborative research while contributing to a longitudinal database. Each grant has a maximum duration of 60 months, divided into five budget periods, ensuring comprehensive support for ongoing studies.
Disability Care & Services Medical Rehabilitation

Field Initiated Projects Program (Development) (363971)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Field Initiated Projects Program (Development) aims to enhance the inclusion and self-sufficiency of individuals with disabilities through innovative research and development. This program supports the creation of tools, methods, and systems that assist people with disabilities, particularly those with significant support needs. With 16 grants available, the initiative will span 36 months, focusing on impactful projects that foster independence, employment, and community integration.
Disability Care & Services Medical Rehabilitation Emerging Technology Development

Traumatic Brain Injury Model Systems Centers

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $560,000 - US $640,000
The Traumatic Brain Injury Model Systems Centers aim to enhance TBI rehabilitation through evidence-based research. These centers focus on generating knowledge to improve health, community participation, and employment outcomes for TBI individuals. Funded by the US HHS Administration for Community Living, the grants support site-specific and collaborative research, contributing to a longitudinal database. Each center can receive varying funding amounts, depending on eligible database participants, with a project timeline of 60 months comprising five 12-month budget periods.
Disability Care & Services Neurological Diseases & Disorders Medical Rehabilitation

Lifespan Respite Care Program: State Grants

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $500,000
The Lifespan Respite Care Program invites state agencies to apply for grants aimed at enhancing respite services for caregivers of individuals with disabilities or chronic conditions. This initiative supports both new states and those re-establishing their programs, focusing on collaboration, training, and outreach to address the respite needs of diverse populations. Approximately ten cooperative agreements will be funded over three years, aligning with federal requirements for lifespan respite care.
Community Services Disability Care & Services Family Services

St. Louis city Grants for Nonprofits Highlights

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Grant Insights : St. Louis city Grants for Nonprofits

Grant Availability

How common are grants in this category?

Uncommon — grants in this category are less prevalent than in others.

89 St. Louis city grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

15 St. Louis city grants for nonprofits over $25K in average grant size

7 St. Louis city grants for nonprofits over $50K in average grant size

21 St. Louis city grants for nonprofits supporting general operating expenses

72 St. Louis city grants for nonprofits supporting programs / projects

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

4,000+ Grants on Instrumentl focused on Academic Scholarship Programs

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for St. Louis city grants for Nonprofits?

Most grants are due in the second quarter.

Q1
23.6%
Q2
28.3%
Q3
21.1%
Q4
27.1%

Typical Funding Amounts

What's the typical grant amount funded for St. Louis city Grants for Nonprofits?

Grants are most commonly $12,000.

$500 $500 Min.
$12,000 $12 K Median
$31,241 $31.2 K Average
$775,000 $775 K Max.

Average Grant Size

What's the typical amount funded for Missouri?

Grants are most commonly $101,542.

$101,542

Total Number of Grants

What's the total number of grants in St. Louis city Grants for Nonprofits year over year?

In 2024, funders in Missouri awarded a total of 44,064 grants.

2022 39,922

2023 39,688

2024 44,064

Top Grant Focus Areas

Among all the St. Louis city Grants for Nonprofits given out in Missouri, the most popular focus areas that receive funding are Philanthropy, Voluntarism & Grantmaking Foundations, Education, and Human Services.

1. Philanthropy, Voluntarism & Grantmaking Foundations

2. Education

3. Human Services

Funding Over Time

How is funding for St. Louis city Grants for Nonprofits changing over time?

Funding has increased by -15.61%.

2022 $4,698,402,122

2023 $5,287,874,816
12.55%

2024 $4,462,369,205
-15.61%

Missouri Counties That Receive the Most Funding

How does grant funding vary by county?

St Louis County, Jackson County, and St Louis City receive the most funding.

County Total Grant Funding in 2024
St Louis County $2,185,711,864
Jackson County $1,234,679,326
St Louis City $1,054,441,922
Greene County $223,079,775
Clay County $178,423,081

Related Grants in Missouri

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