Best St. Louis County Grants for Nonprofits in Missouri

Detroit HBCU Scholarship Endowment

This generous Detroit HBCU Scholarship provides need-based awards to support students who are in one of the eligible zip codes of Detroit.

The purpose of the Detroit HBCU Scholarship Endowment Fund is to provide 1 (one) annual, renewable, and need-based scholarships up to $5,000 (five-thousand dollars) to students graduating from a high school with a Detroit address or students transferring from a metro-Detroit community college to attend a partner HBCU.

United Way of Greater St. Louis

Our Mission: The United Way of Greater St. Louis mission is to mobilize the community with one goal in mind – helping people live their best possible lives. We unite people, resources and funding to help build strong and equitable communities where everyone can thrive.

Safety Net

United Way’s Safety Net is a collaborative network of agencies that deliver an array of essential direct services to address the region’s most pressing needs, helping families and individuals remain and work toward stability. Safety Net agencies provide direct services that address basic, urgent needs – such as access to food and housing— as well as supports that help move individuals and families toward stability, including education, health and well-being, workforce access, and financial mobility.

Safety Net Funding

United Way of Greater St. Louis is now accepting applications for its Safety Net Funding cycle and invites all eligible agencies across its 16-county region in Missouri and Illinois, including those not currently receiving United Way funding, to apply. United Way equips 160 local nonprofits with vital funding and training resources to support measurable impact across its five impact areas. Organizations selected will receive a three-year contract and become part of the UWGSL member agency network.

United Way’s Impact Areas

• Basic Needs 
• Community Stability and Crisis Response 
• Early Childhood and Youth Success 
• Health and Wellbeing 
• Jobs and Financial Mobility 

While needs are great across the five impact areas, United Way will use data derived from its landscape analysis of community needs to inform how service areas will be prioritized to ensure the region has access to a strong and resilient network as needs arise.

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

New Program

PLTW Computer Science

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to high schools interested in implementing or expanding their PLTW Computer Science programs.

At a time when computer science affects how we work and live, PLTW Computer Science empowers students in grades 9-12 to become creators, instead of merely consumers, of the technology all around them. The program's interdisciplinary courses engage students in compelling, real-world challenges. As students work together to design solutions, they learn computational thinking – not just how to code – and become better thinkers and communicators. Students take from the courses in-demand knowledge and skills they will use in high school and for the rest of their lives, on any career path they take.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Computer Science programs beginning in the next academic year.

PLTW Program Status

Program Expansion

The Jean Griswold Foundation

The Jean Griswold Foundation (JGF) is a non-profit organization dedicated to supporting Caregivers through educational opportunities and scholarships. 

Our Mission

The mission of the Jean Griswold Foundation is to support Caregivers by providing educational scholarships* to enable them to further their training, enhance their careers, and better assist the clients they serve.

By offering educational scholarships*, our Foundation will not only make a positive impact on the Caregivers themselves, but also the clients they assist and the home healthcare agencies where they are employed, as well as help advance the overarching home-care industry.

Scholarships will be paid directly to the federally accredited educational institutions of the winning Scholars’ choosing.

Empowering Caregivers Through Education

The Jean Griswold Foundation Scholarship Program awards scholarships to deserving Caregivers who wish to further their education in a care-related field. Applicants do not have to be associated with Griswold in any way, and the funds will be paid directly to the institution where the caregiver will be receiving education.  

Our Winter 2026 Scholarship Application period is now open! Applications will be accepted until 11:59pm ET August 31, 2026. Join our email list to get the first notice of all Scholarship happenings.  

Where would we be without Caregivers? 

Their selflessness is astounding, yet they are often overlooked and underappreciated. 

The Jean Griswold Foundation is dedicated to supporting Caregivers, the backbone of the care industry. We provide educational scholarships so Care Professionals can further their training, enhance their skills, elevate their careers, and better assist the people they serve.

PLTW Launch

PLTW Launch's 43 interdisciplinary modules bring learning to life. The program empowers students to adopt a design-thinking mindset through compelling activities, projects, and problems that build upon each other and relate to the world around them. And as students engage in hands-on activities in computer science, engineering, and biomedical science, they become creative, collaborative problem solvers ready to take on any challenge.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Launch programs beginning in the next academic year.

PLTW Program Status

New Program

Grant Award and Distribution Schedule

• Total Award: $15,000
  • First Year: $10,000
  • Second Year: $5,000

PLTW Launch

PLTW Launch's 43 interdisciplinary modules bring learning to life. The program empowers students to adopt a design-thinking mindset through compelling activities, projects, and problems that build upon each other and relate to the world around them. And as students engage in hands-on activities in computer science, engineering, and biomedical science, they become creative, collaborative problem solvers ready to take on any challenge.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Launch programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing or expanding their PLTW Gateway programs.

Middle school is a time of exploration, a time when students are figuring out what they're passionate about today and how that relates to who they'll become tomorrow. During this transitional time, PLTW Gateway's 10 units empower students to lead their own discovery. The hands-on program boosts classroom engagement and excitement, drives collaboration, and inspires “aha! moments” and deep comprehension. And as students engage in PLTW's activities in computer science, engineering, and biomedical science, they see a range of paths and possibilities they can look forward to in high school and beyond.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Gateway programs beginning in the next academic year.

PLTW Program Status

Program Expansion

Ameren has partnered with PLTW to inspire students and provide the hands-on STEM learning experiences necessary to thrive in life beyond the classroom. Ameren is a long-time supporter of K-12 STEM education in the region and is working with PLTW to provide grant support to schools interested in implementing or expanding their PLTW Gateway programs.

Middle school is a time of exploration, a time when students are figuring out what they're passionate about today and how that relates to who they'll become tomorrow. During this transitional time, PLTW Gateway's 10 units empower students to lead their own discovery. The hands-on program boosts classroom engagement and excitement, drives collaboration, and inspires “aha! moments” and deep comprehension. And as students engage in PLTW's activities in computer science, engineering, and biomedical science, they see a range of paths and possibilities they can look forward to in high school and beyond.

Through this partnership, Ameren has committed funds to support PLTW grants to schools interested in starting or expanding PLTW Gateway programs beginning in the next academic year.

PLTW Program Status

New Program

Grant Award and Distribution Schedule

• Total Award: $20,000
  • First Year: $10,000
  • Second Year: $10,000