Best Grants for Small Nonprofits in Texas

The Reeves Foundation supports research aimed at understanding and treating macular degeneration, a condition that has personally affected the founder's family. Established in 1997, the foundation allocates 50% of its grants to research and the other half to local charities in Columbus, Indiana. Nonprofit organizations exempt under IRS code 501(c)(3) are eligible to apply, but funds cannot be used for administrative costs. The foundation prioritizes equipment purchases and partnerships with other funding sources.

The Craig H. Neilsen Foundation's Creating Opportunity & Independence Grant supports programs and research that enhance the quality of life for individuals with spinal cord injuries (SCI). It welcomes applications from nonprofit organizations and rehabilitation facilities in the U.S. and Canada, focusing on projects that foster independence, community participation, and capacity-building. Priority is given to initiatives that demonstrate broad impact and involve individuals with SCI, ensuring their needs and perspectives shape the proposed activities.

The Healthy Tomorrows Partnership for Children Program (HTPCP) aims to enhance access to essential preventive clinical and public health services for children through community-driven initiatives. Funded by the US HHS: Health Resources & Services Administration (HRSA), this program focuses on empowering local communities to implement effective strategies that improve children's health outcomes and promote overall well-being. Projects funded under this initiative will play a vital role in ensuring healthier futures for children.

About

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Rett Syndrome (RS) Fund

Help with healthcare costs for Rett syndrome.

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses. Check your eligibility with our quick and easy tools below. If this fund is open, apply today for an instant approval decision and use your grant funding right away

About the disease

Rett syndrome (RS or RTT) is a rare, genetic neurological disorder that causes a loss of motor and spoken language skills, as well as other physical and neurologic impairments early in life.

Diagnosis codes

F84.2

The Alcon Foundation Grant aims to enhance eye care services and improve patient access, with a focus on educational and training programs. The foundation also supports cultural and community development initiatives that uplift the quality of life in areas where Alcon operates, including cities like Fort Worth, Houston, and Irvine. However, it does not fund non-501(c)(3) organizations, athletic leagues, or fundraising events, among other exclusions.

The Primary Biliary Cholangitis (PBC) Fund, established by the Patient Advocate Foundation, offers vital financial assistance to patients managing the costs of treatment for primary biliary cholangitis. This fund covers out-of-pocket healthcare expenses such as medication copays and health insurance premiums, enabling individuals to access necessary treatments. Since its inception, the foundation has empowered millions by providing personalized support and resources, aiming to improve patient care and health outcomes.

The Pompe Disease Health Equity Fund, supported by the Patient Advocate Foundation, offers crucial financial assistance to patients diagnosed with Pompe disease. This fund helps cover out-of-pocket healthcare costs, including medication copays and health insurance premiums. Eligibility requires a confirmed diagnosis and treatment plan, along with meeting specific income criteria. With a mission to enhance health equity, the fund empowers patients to access necessary care and improve their quality of life.

The Pompe Disease Fund, supported by the Patient Advocate Foundation, offers vital financial assistance to individuals diagnosed with Pompe disease. This fund covers out-of-pocket healthcare costs including medication copays and health insurance premiums. Eligible patients must have a confirmed diagnosis and be receiving treatment or planning to start within 60 days. With over 3.8 million patients helped since its inception, the fund aims to alleviate financial burdens and enhance access to necessary treatments.

The FWW Research Award supports innovative, short-term studies aimed at enhancing women's health, particularly in areas such as cardiovascular disease, female cancers, and hormonal impact on health. Eligible applicants include MDs and PhDs affiliated with accredited institutions. The program prioritizes research with direct clinical applications and seeks proposals that promise to attract additional funding for further study. Notably, sociological research is excluded from funding consideration.

The National Institute of Nursing Research (NINR) plans to publish a funding opportunity announcement for Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional). This initiative aims to strengthen nursing-led programs that foster community-partnered research addressing significant health issues. By enhancing interdisciplinary research capacities, the program will establish centralized resources in nursing schools, build expertise in community partnerships, and support nurse-led teams in developing, implementing, and evaluating impactful research projects.

The BJS FY 2026 Criminal History Record Assessment and Research Program (CHRARP) aims to enhance the Bureau of Justice Statistics' ability to analyze recidivism and criminal history data. This program will support the standardization of criminal records across jurisdictions, enabling accurate statistical analyses. By refining existing data coding systems and addressing data quality issues, the CHRARP will improve research on offenders' patterns and careers, ultimately contributing to effective criminal justice policies.

The L.B. Danford Charitable Trust Grant supports educational, health, human services, and religious initiatives primarily in Brazos and Grimes Counties, Texas. Established in 1992, it honors Luther Bernard Danford's legacy, providing annual grants averaging $40,000. Eligible organizations must be 501(c)(3) exempt and located within the specified counties. Applications are accepted year-round, with a deadline of July 31 for September's annual meeting review. Note that the trust does not fund endowments.

The Brookreson Trust Grant aims to support financing homes for the blind and organizations that assist them. This grant is targeted towards 501(c)(3) exempt organizations across all states. The program focuses on key areas such as education, health, and human services, ensuring that vital resources are directed towards enhancing the quality of life for the visually impaired community. Grants are specifically intended for initiatives that facilitate housing and support services.

The Ted & Shannon Skokos Foundation Grant, established in 2008, supports nonprofit organizations in arts, education, humanity, and faith. It prioritizes visionary leadership, community impact, sustainability, organizational strength, and collaboration. The foundation seeks to fund eligible 501(c)(3) nonprofits that align with its mission and positively influence communities, particularly in Dallas, Texas, and Arkansas, where the founders have personal connections.

Extreme Terrain’s Clean Trail Initiative Program aims to enhance trail integrity by supporting groups in the U.S. with grants for projects like trail clean-up, restoration, and expansion. Eligible applicants include Wrangler and 4x4 clubs, environmental organizations, and those managing public or private trails. The initiative emphasizes responsible off-roading while encouraging volunteers to engage in improving our natural landscapes. This program fosters community involvement and promotes sustainable practices in outdoor activities.

The NHGRI's Analysis, Visualization, and Informatics Lab-space (AnVIL) program is set for a limited competition renewal to enhance a cloud-based platform that supports genomic research. With over 5 petabytes of data accessible to researchers, AnVIL fosters collaboration and innovation while adhering to FAIR principles. The renewed focus will include improved scalability, interoperability, and robust security measures. Additionally, training initiatives will ensure researchers maximize the potential of AnVIL's multimodal datasets. The funding opportunity is expected in 2027.

The Radiation Oncology-Biology Integration Network (ROBIN) Centers, funded by the National Cancer Institute (NCI), aims to enhance national radiation oncology infrastructure through collaborative research. This initiative supports studies on biological responses to radiation treatment in cancer patients, focusing on understanding tumor and tissue changes. By integrating various scientific disciplines and collecting comprehensive data, ROBIN intends to improve cancer care, optimize treatment strategies, and accelerate translational discoveries to enhance patient outcomes.

Who We Are

Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.

Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship

East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.

The Volunteer Fire Dept Program, established by the Wichita Falls Area Community Foundation and The Priddy Foundation, aims to enhance community life in Wichita Falls through charitable giving. Since 2006, the program has supported local volunteer fire departments, promoting their needs and fundraising efforts. Eligible fire departments from Texas and Oklahoma counties can apply, provided they meet specific criteria and waiting periods for grants. The program emphasizes community support and responsible funding.

Biochemical and Molecular Characterization of Marstacimab and TFPI Pathways

This competitive grant encompasses research aimed at elucidating molecular and cellular mechanisms underlying marstacimab-TFPI interactions, including but not limited to differential expression of tissue factor and TFPI in various tissues, binding kinetics, and other biochemical properties. Projects should seek to advance foundational understanding of these interactions through innovative approaches in biochemistry, molecular biology, and related disciplines.

Funding Range and Project Length

Individual projects requesting up to $50,000 USD will be considered.

Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.

Maximum project length is 1 year.

The Alexandra Armstrong Innovation Grant, offered by the Foundation for Financial Planning, recognizes nonprofits that demonstrate exceptional creativity and impact in pro bono financial planning services. Established in honor of Alexandra Armstrong, a dedicated advocate for community service and financial planning, this grant aims to expand access to vital financial advice for underserved populations. Eligible organizations can apply annually to receive funding that supports innovative programs designed to enhance financial well-being.

The Scheidel Foundation offers Integrative Cancer Care Grants aimed at enhancing the quality of life for individuals living with cancer. This initiative supports organizations that promote awareness and adoption of integrative practices, targeting both the medical community and patients. The Foundation seeks proposals that foster long-term solutions and innovative programs, focusing on evidence-based information and practices. Grants are available through a selective process, emphasizing transformative impacts in the field.

Viasat Corporate Giving focuses on enhancing community strength through various initiatives. Their commitment includes support for military and veteran outreach, skills-based volunteering, and promoting STEAM education, particularly for underserved communities. By engaging employees in these programs, Viasat aims to create meaningful connections and empower individuals, ensuring that families and service members thrive. This holistic approach not only fosters community growth but also inspires the next generation of STEM leaders.

The Indian Land Tenure Foundation (ILTF) offers a Cultural Awareness Grant aimed at revitalizing the cultural and spiritual values related to Indian land. This initiative supports American Indian nations in enhancing their ties to the land, which is vital for traditional practices and beliefs. Eligible entities include tribal governments and 501(c)(3) nonprofit organizations. Ineligible activities encompass advocacy efforts, land purchases, and direct funding to individuals, ensuring resources focus on community-centered cultural preservation.

The Truth Initiative Tobacco/Vape-Free College Program offers grants of up to $20,000 to U.S. colleges and universities aiming to implement 100% tobacco/vape-free policies. Additionally, grants of up to $10,000 are available for schools looking to enhance existing smoke-free policies to include e-cigarettes. This initiative seeks to engage students and create support from faculty and staff, ultimately fostering healthier campus environments.

The Phoebe Apperson Hearst Awards honor excellence in family engagement by recognizing PTAs that achieve top rankings through the National PTA School of Excellence program. These awards celebrate PTAs that effectively engage families in student success and school improvement initiatives. By participating, PTAs can develop best practices, create inclusive communities, attract action-oriented members, and gain national recognition as leaders in building strong family-school partnerships.

The CDC's grant aims to enhance global public health emergency responses by engaging partners to improve rapid detection and intervention strategies. It seeks to build sustainable programs that strengthen resilience in communities affected by humanitarian crises. With periodic openings for applications, this initiative ensures a diverse roster of partners ready to tackle emerging public health threats effectively. The program underscores the importance of federal support in managing complex health emergencies worldwide.