Best Unrestricted Grants for Nonprofits

National Federation of the Blind of Maryland

The National Federation of the Blind of Maryland (NFBMD), an affiliate of the National Federation of the Blind, is an organization that believes in the full capacity of blind people, and has the power, influence, diversity and determination to help transform our dreams into reality. Members work together for a brighter tomorrow by raising expectations so that blind persons can have the life they want.

The National Federation of the Blind of Maryland is a 501c(3) nonprofit made up of blind people of all ages, their families and friends. Our strong local chapters and divisions, and well-trained leaders help newly blind people adjust to vision loss, and promote the full participation and integration of blind people in our communities. We bring our collective experiences together to effect change at the state and national level.

Sharon Maneki Youth Empowerment Grant Information

The National Federation of the Blind of Maryland offers youth empowerment grants for blind and visually impaired students in elementary and secondary school. These grants help deserving students take advantage of some wonderful training opportunities available in Maryland and around the country.

Requirements

Students who receive grants are required to perform at least one of the following reflection activities within 45 days of completing the program. Parents may assist with this activity. Failure to complete a reflection activity may impact future eligibility for NFB support.

Reflection Activities:

• Prepare a short article of at least 500 words for publication in the NFB of Maryland's newsletter, The Spectator, or for posting on the NFB of Maryland Web site.
• Attend an NFB meeting. Give an overview of the program attended, and describe the benefits of the experience (approximately a 3 to 5 minute presentation).

The CSWEP Environmental Professionals Grant Program, organized by the Connecticut Society for Women Environmental Professionals, aims to empower women in environmental fields. It funds local projects in Connecticut that contribute positively to the environment. The program prioritizes applications that demonstrate significant environmental benefits, ranging from clean-up initiatives to educational programs. Through this grant, SWEP-CT fosters leadership and collaboration among women professionals, enhancing their skills and promoting public service in environmental endeavors.

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA State Fund Grant Program - Rhode Island

The Friends of NRA State Fund Grant Program provides supplies, equipment, and financial support to a variety of qualified groups and programs at the local level; geared towards youth, women, law enforcement, veterans, the disabled, and the general public, including:

• General shooting programs
• Competitive shooting
• Education, training and safety
• Hunting and conservation
• Community outreach
• Historical education

Grant funding must be used to further a charitable purpose as defined by the Internal Revenue Code under section 501(c)(3) and accompanying rules, regulations, and other IRS law and materials.

The SNAP Employment and Training (NE) program, by the Nebraska Department of Health and Human Services, aims to support low-income adults, including SNAP recipients, in gaining employment through various training services. These services include supervised job searches, job search training, job retention assistance, basic education, career or technical training, and on-the-job training. The initiative seeks to empower participants with the skills and resources necessary to succeed in the workforce.

The Hampton Roads Community Foundation offers Community Grants for Seed & Program Funding in Health & Wellness to enhance the wellbeing of southeastern Virginia residents. These grants support nonprofits focused on improving access to health services, promoting healthy behaviors, and addressing health disparities. Eligible applicants include 501(c)(3) organizations serving the South Hampton Roads area, with priority given to programs that enhance health literacy and connect individuals to essential care.

The Florida Blue Foundation's Driver of Health: Food Security Grants aim to enhance food security for families in vulnerable communities. By improving access to affordable, nutritious food, the initiative seeks to mitigate health risks associated with food insecurity. Eligible applicants include nonprofit organizations and community agencies in Florida, focusing on educational programs that promote self-sufficiency. Priority will be given to areas with high food insecurity, ensuring that targeted populations receive essential support.

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA State Fund Grant Program - South Carolina

The Friends of NRA State Fund Grant Program provides supplies, equipment, and financial support to a variety of qualified groups and programs at the local level; geared towards youth, women, law enforcement, veterans, the disabled, and the general public, including:

• General shooting programs
• Competitive shooting
• Education, training and safety
• Hunting and conservation
• Community outreach
• Historical education

Grant funding must be used to further a charitable purpose as defined by the Internal Revenue Code under section 501(c)(3) and accompanying rules, regulations, and other IRS law and materials.

The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.

The Suffolk Foundation's Community Impact Grants Program supports nonprofit organizations in Suffolk and Western Tidewater, Virginia, focusing on local projects in health, education, arts, and more. Grants prioritize organizations with strong local presence and leadership, funding direct project costs to enhance community impact. Eligible applicants include tax-exempt public charities serving residents in these areas. Exclusions apply for non-tax-exempt entities, individuals, and projects outside the service area, ensuring funds directly benefit the community.

The PLTW Gateway Program Expansion grant, funded by Huber in partnership with Project Lead The Way Inc., offers $10,000 to public schools aiming to enhance their existing PLTW Gateway programs for the 2026-2027 academic year. Eligible schools can use the funds for adding new units, increasing class periods, or training additional teachers. Annual reports and surveys are required to assess the program's impact and effectiveness.

The PLTW Gateway grant supports public schools in offering innovative STEM education. Grantees must provide at least one PLTW Gateway unit during the 2026-2027 academic year, with an additional unit each subsequent year. The total grant award is $20,000, distributed in two installments. Grantees are required to submit annual reports and assist in student and teacher surveys to ensure ongoing program improvement. Eligible districts span several states, including Arkansas, Georgia, and Texas.

The Norfolk Southern In-Kind Donation Grant supports organizations seeking physical donations of materials that align with their focus areas, including safety, sustainability, workforce development, and thriving communities. This grant is available year-round, with no application deadline. Recipients must be located within Norfolk Southern territory and are encouraged to apply for resources that will enhance their community projects and initiatives, fostering growth and resilience.

The Harry John Erbe Charitable Trust provides grants to tax-exempt organizations in support of charitable, religious, scientific, literary, and educational initiatives. Focused primarily on organizations in Pennsylvania, particularly Harrisburg, the trust emphasizes areas such as arts, education, health, and human services. Eligible groups must comply with Section 501(c)(3) of the Internal Revenue Code. This funding opportunity aims to enhance community services and promote cultural and educational development.

The Labcorp Charitable Foundation, a private 501(c)(3) entity, aims to enhance healthcare access and education for all. With grant opportunities focusing on food programs, healthcare services for underserved populations, and STEM initiatives, it seeks to support community health and well-being. Organizations eligible for funding must be U.S.-based and hold tax-exempt status. Requests are reviewed biannually, in March and September, to foster impactful community projects.

The Edelweiss Foundation is a philanthropic organization dedicated to supporting transformative initiatives in Greater Cincinnati. Their mission focuses on enriching the community by funding projects led by visionary leaders. The foundation primarily supports 501(c)(3) nonprofits in various sectors, including education, healthcare, and community development, aiming to enhance the physical, intellectual, and emotional well-being of Cincinnatians. With a commitment to fostering growth and potential, the foundation seeks proposals that align with its mission.

The Pat and John MacTavish Fund, established in 2007 by John Mac Tavish in memory of his wife Pat, provides scholarships aimed at encouraging young women to pursue higher education in the hard sciences. Awarded by the Grand Haven Area Community Foundation, scholarships are competitive and based on criteria such as financial need and academic achievement. Applicants from Northern Ottawa County or specific school districts are eligible. The fund emphasizes the importance of education in fields such as math, chemistry, and computer science.

The Charlevoix County Community Foundation offers the Environment and Land Use Grants to support nonprofit projects that promote environmental education, protection, and sustainability within the Lake Charlevoix Watershed. This initiative encourages collaboration and innovative approaches to community needs, fostering long-term positive impacts. Eligible applicants include tax-exempt nonprofits, government units, and educational institutions that serve the Charlevoix County area. The Foundation prioritizes well-planned proposals that align with community goals and benefit natural resources.

The Environmental Response Fund (ERF) Grant Program in Hennepin County provides essential funding for the assessment and cleanup of contaminated sites. It prioritizes projects that address significant contamination, demonstrate readiness, and support public development and affordable housing initiatives. Eligible applicants include municipalities and nonprofit organizations. This initiative promotes economic development and sustainable practices, ensuring healthier communities while tackling environmental challenges.

The David, Helen and Marian Woodward Fund, established by Marian Woodward Ottley in 1974, aims to support non-profit organizations in Georgia and neighboring states. The fund prioritizes capital projects and educational programs that enhance graduation rates, particularly those with religious affiliations. Grants are awarded exclusively to 501(c)(3) organizations, while governmental agencies can also apply. The foundation's mission underscores a commitment to improving the world for future generations.

The Zimmerman, Edward and Beverly Memorial Scholarship Fund offers $1,000 to West Noble High School seniors pursuing higher education at a college or university, with priority given to those demonstrating community service and maintaining a GPA between 2.50 and 3.00. Preference is also given to students studying agriculture, education, social work, or accounting. This scholarship reflects the values of its donors, Edward and Beverly, who were dedicated community members and supporters of local education.

The W R Berkley Corporation Charitable Grant Program supports local 501(c)(3) organizations in Central Iowa, SW Minnesota, and Eastern Nebraska. With a focus on health, community betterment, youth development, education, and food insecurity, grants are awarded twice a year. There are no limitations on request sizes, but only one grant per organization is accepted annually. Funding decisions prioritize organizations with a proven track record of efficiency and success in serving their communities.

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

• Significantly expand pediatric cancer research capacity in Florida
• Improve both research and treatment through greater pediatric enrollment in clinical trials networks
• Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

• Prevention and Treatment
• Screening
• Obesity
• Treatment-Related Morbidities
• Technology Transfer Feasibility (TTF)
• Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: High-Risk, High-Reward Clinical Research

Research in this mechanism of support test innovative therapeutic approaches or novel treatment modalities with transformative potential but substantial uncertainty regarding feasibility, safety, or efficacy. These include first-in-human studies, unconventional drug repurposing, or interventions targeting previously undruggable pathways. The high-risk component encompasses potential trial failure, unexpected adverse events, or negative results that could redirect research programs. The high-reward potential includes paradigm-shifting breakthroughs, dramatic clinical improvements, or validation of novel biomarkers that revolutionize personalized medicine.

Maximum Duration: 48 months

The Wade Family Foundation Grant supports non-profit organizations in Southern Utah that align with the foundation's values, including education, health care, and combating homelessness. Established by Stephen and Marcia Wade, the foundation prioritizes direct program needs over overhead costs. Eligible organizations must have 501(C)(3) status and operate within the specified geographical area. The foundation actively seeks to improve the quality of life in the community through strategic funding and support.

The Social-Impact Investment Pitch Competition aims to enhance the vitality of Southwestern Pennsylvania, particularly in Pittsburgh, by fostering economic development, wildlife conservation, and community health. The Foundation invites nonprofits, public agencies, and socially-driven for-profit companies to apply for funding to implement innovative ideas that address societal challenges. Applications are open to U.S.-based organizations seeking capital and project support, with a focus on creating lasting positive change in the community.

The JRCT Sustainable Future Grant Program aims to support innovative projects addressing climate change and social injustice. It prioritizes funding for organizations that tackle root causes of conflict, promote sustainable practices, and amplify marginalized voices. The trust is particularly interested in proposals that foster community power, challenge economic inequalities, and develop alternative models to consumerism. With a focus on long-term impact, JRCT encourages grassroots initiatives that engage diverse communities in creating systemic change.

The Leon M. Seidel Memorial Trust Fund Grant supports charities in Bordentown, NJ. Established in 1967, it aims to benefit local residents through various charitable causes, including arts, education, health, and human services. To be eligible, organizations must be 501(c)(3) exempt. Applications are accepted year-round, with a submission deadline of April 1 for annual review. This grant promotes community welfare and addresses diverse needs.

The Hazel Miller Foundation Grant supports charitable projects in South Snohomish County, focusing on education, youth services, poverty alleviation, civic services, environmental initiatives, culture, and diversity. Applications are accepted at any time, with quarterly review cycles. The Foundation prioritizes projects that deliver significant community impact and are managed by tax-exempt organizations. Grants are not available for individuals. This initiative aims to foster a resilient and thriving community.