Best Volusia County Grants for Nonprofits in Florida

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Patient Travel Grant Program

A mesothelioma diagnosis and treatment often require the patient and their family to incur numerous expenses as part of their treatment. Travel to treatment, alone, can cause a significant financial burden on the patient, which might even cause the patient to not seek treatment away from home, even it’s their best option. To ensure that all patients have the ability to seek specialized help and treatments, the Mesothelioma Applied Research Foundation administers its Travel Grant Program.

The Meso Foundation’s Patient Travel Grant Program, founded by Mary and Bob Cosentino, provides travel grants to patients and one caregiver traveling for an initial consult and/or for clinical trial treatments.

• The type of eligible travel must fall into at least one of these two categories:
  • One trip for one initial consultation with a mesothelioma specialist.
  • Multiple trips to participate in an interventional clinical trial (found on clinicaltrials.gov).

Mesothelioma Applied Research Foundation Inc

The Mesothelioma Applied Research Foundation is the only nonprofit charity organization dedicated to ending mesothelioma, and the suffering caused by this cancer, by:

• funding research to improve treatment options;
• providing treatment support and education for patients and their families;
• and advocating for federal funding of research.

The mission of the Mesothelioma Applied Research Foundation spans across four distinct areas: through research, education, support, and advocacy the Foundation seeks to eradicate the vicious effects of mesothelioma. Led by the Board of Directors, our team works collaboratively to develop and administer our programs, and to fundraise to pay for those programs (the Foundation is funded by private individual and corporate contributions only — it does not receive any government funding).

Bret A. Rosenthal Patient Assistance Fund

Patients diagnosed with cancer at a younger age often face greater financial burdens. This is a time in a patient’s life when they are raising a family, starting a career, or have not accumulated savings. For patients 49 and under, the Foundation administers the Bret A. Rosenthal Patient Assistance Fund grant program. This program is made possible by the generosity of the Rosenthal family.

Maternal Health Grant Program

Florida Blue Foundation is funding approximately $3 million for this grant program, offering four year grants. The total funding request for the grant period should fall within the range of $300,000 to $400,000, with an approximate annual allocation of $75,000 to $100,000.

Utilizing the Full Power of Empire AI Request for Applications

The Simons Foundation (SF) intends to support cutting-edge mathematics and basic science research, drawing on the advanced computational power of the Empire AI.

Toward this goal, SF plans to initiate a new program to fund six to 12 proposals through a competitive open call to the Empire AI research community.

A successful proposal will outline an ambitious two-year research program in one of the following fields, or at their intersections: computational astrophysics and physics, computational biology, mathematics, neuroscience and computational physical chemistry. Each proposal will necessarily rely on the development and utilization of foundational machine learning models, aimed at solving problems of fundamental importance in the above-listed disciplines.

Computational biophysics, neuroscience, ecology and evolution, plant biology, optimal transport, multiscale physics, fluid dynamics and numerical general relativity are representative examples of fields that could use multinode clusters of GPUs of Empire AI, which is a requirement of the program. All submitted proposals should detail how their work will use multinode clusters of GPUs in Empire AI. Proposals focused on data curation and creation of datasets can be considered in exceptional cases, as long as the attained data will be used by the proposers for solving scientific problems as part of the same proposal.

The program’s total budget is expected to be $6 million USD over a two-year period.

Funding

Award Amount: There is no maximum budget total for an individual award. The total amount requested should reflect the proposed research. All award amounts are inclusive of indirect costs (see our grant policies). Please note that we anticipate funding six to 12 applications. The total program’s budget of $6 million USD over two years will be spread across all awards.

Award Duration: June 1, 2027, through May 31, 2029.

Number of Awards: We expect to select six to 12 applications for funding.

The Affordable Rural Cooperative (ARC) Energy Program, initiated by the Rural Utilities Service (RUS), aims to enhance rural electric systems through substantial funding of approximately $175 million. This initiative focuses on increasing emission-free nuclear power and improving transmission infrastructure efficiency, promoting long-term reliability and affordability. Eligible entities include electric cooperatives serving rural areas and their subsidiaries. The program aligns with the Inflation Reduction Act (IRA) to achieve significant reductions in greenhouse gas emissions, thus fostering a sustainable energy future.

The Drexel Fund Founders Program is a one-year paid fellowship that helps outstanding leaders already on the path to launching a school continue to plan and open an innovative and effective private school in one of The Drexel Fund’s target states: Arizona, Florida, Indiana, Iowa, North Carolina, Ohio, Tennessee and Wisconsin. The tenth cohort of the Founders Program is designed for entrepreneurs who will begin the fellowship in Summer 2027 and be ready to launch a new private school in Fall 2028.Through the fellowship, school founders will develop their school’s education model and finalize the nuts and bolts of their school launch, including board and budget development, market analysis, facility location, student recruitment and staff hiring. Founders will create a plan that will make it possible for their school to achieve top-tier results for children while maintaining a sustainable financial model.

Greenawalt Foundation

Our Mission

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Community Grant

The Greenawalt Foundation extends its commitment to opportunity and well-being through community grants that support nonprofit organizations serving women, children, and vulnerable populations. These grants focus on programs that promote safety, stability, and self-sufficiency, including initiatives supporting domestic violence recovery, foster care, the working poor, and animal welfare. Foundation support strengthens the social fabric of communities and expands access to essential resources for those in need. Through these efforts, the Foundation helps build stronger, more compassionate communities where individuals and families can thrive.

Areas of Support

We focus our community grants on initiatives that align with our mission of compassion, opportunity, and empowerment. Areas of support may include:

• Domestic violence prevention and survivor support
• Programs for women and children
• Family assistance and poverty relief initiatives
• Foster care, youth development, and educational support
• Animal welfare and community-based rescue programs

Greenawalt Foundation

Building Stronger Communities

At The Greenawalt Foundation, we believe that opportunity is the foundation of prosperity. By supporting organizations that educate, train, and empower people in the trades, we’re helping to build a stronger, more sustainable future for all.

Skilled Trades Grant Opportunities

The Greenawalt Foundation advances opportunities in the skilled trades through funding for accredited pre-apprenticeship and apprenticeship programs, workforce training initiatives, and youth career exploration experiences. These programs promote technical readiness and connect STEM education to modern trades careers, building a stronger, more sustainable workforce. Foundation support focuses on expanding access and creating equitable pathways to prosperity for individuals pursuing skilled trades careers. Through these efforts, the Foundation helps develop the next generation of skilled professionals who will shape the future of our communities.

Eligible Grant Categories

• Skilled Trades Training Support
• Pre-Apprenticeship or Apprenticeship Programs
• Youth Career Exploration Camps

Seeding Research, Networking, and Capacity Building at Minority-Serving Institutions

Introduction & Purpose

RWJF is committed to ensuring everyone has a fair and just opportunity to be as healthy as possible. To achieve this goal, we support research that examines the historical and systemic factors that cause health inequities. Some of those determinants are poverty, discrimination, and limited access to quality education, housing, safe environments, and healthcare. As attacks on data and academic freedom and ongoing funding cuts to federal health equity research and programs continue, philanthropy’s work to achieve fair and equitable health, including a more equitable research funding ecosystem, is more important than ever. While philanthropic support for Minority-Serving Institutions (MSIs) has increased in recent years, there is more to be done to rectify historical disparities in funding. 

This call for proposals (CFP) provides support to health equity research centers at MSIs to strengthen research infrastructure and capacity-building. Capacity-building will help develop staff, skills, culture, resources, and systems that enable research to happen effectively. Specific work that RWJF may fund under this CFP includes specific skill or methodology training; faculty release time; support for research assistants, advisors, and project staffing; mentoring, professional development and collaboration, and more.

Through this CFP, RWJF will expand its efforts to transform deeply rooted beliefs about which data and research methods are valued, whose perspectives are prioritized, and which populations deserve resources. By supporting the infrastructure and capacity-building needs of MSIs, this opportunity strengthens their ability to generate critical evidence and to cultivate transformative, actionable solutions toward health equity. 

RWJF believes in health equity research that is grounded in systems thinking; supports and disseminates evidence identifying and implementing structural solutions to racial and health inequities. This CFP seeks mission-aligned institutions to participate in cohort-style peer learning to advance their ability to engage in health equity research and apply for competitive funding opportunities in the future.

Although no single philanthropy can fill the gap left by federal funding cuts, this CFP demonstrates strong support for research, historically underrepresented researchers, and research centers that are positioned to pave the way toward a future where health is not a privilege, but a right.

Hurricane Response Marine Debris Removal Fund

2027 Request for Proposals

National Fish and Wildlife Foundation (NFWF) and the National Oceanic and Atmospheric Administration (NOAA) established the Hurricane Response Marine Debris Removal Fund to support projects to assess, remove, and dispose of marine debris in and around coastal communities impacted by hurricanes and other episodic storm events.

The Hurricane Response Marine Debris Removal Fund will award grants to remove damaging marine debris from coastal areas of communities impacted by hurricanes or other natural disasters. Priority will be placed on debris removal efforts that reduce impacts on communities and industry as well as prevent further harm to habitats and fish and wildlife populations. Funding has been made available by the FY 2025 American Relief Act, P.L. 118-158.

The Hurricane Response Marine Debris Removal Fund will award up to $11 million in grants in 2027. While there is no minimum or maximum expected award amount, funding request amounts should be appropriate relative to the overall scale and impact of the project.

The State Recreational Boating Safety (RBS) Grant Program, administered by the US Department of Homeland Security's U.S. Coast Guard, aims to enhance safety and enjoyment on America's waterways. This federal program provides grants to designated state agencies to reduce boating accidents, injuries, and fatalities. Although not open to the public, it plays a critical role in ensuring safe recreational boating experiences by implementing effective safety measures, thereby promoting public welfare and environmental protection.

The Hispanic-Serving Institutions Education Grants Program aims to enhance the educational capabilities of HSIs through innovative teaching and community development initiatives. Funded projects will not only serve the Hispanic population but will benefit the entire student body, promoting inclusivity. This program encourages applications that integrate applied research with community outreach, fostering experiential learning opportunities for students. The initiative aspires to set benchmarks for educational excellence at regional and national levels.

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

The Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center (DRIC), supported by NINDS, aims to enhance diagnostic capabilities for UDN participants. This initiative will foster collaboration among clinical networks and stakeholders to develop innovative diagnostic tools and strategies. The DRIC will also focus on the systematic evaluation of unresolved UDN cases, advancing genomic and non-genomic diagnostics, and discovering novel disease-associated genes. This forecast allows potential applicants to prepare and collaborate effectively for future projects.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment through regional clinical enrollment coordinating centers (RCCs). Supported by the National Institute of Neurological Disorders and Stroke (NINDS), this initiative promotes collaboration for clinical trials that focus on acute stroke treatment, prevention, and rehabilitation. While applications are not currently being solicited, this notice serves to prepare potential applicants for future opportunities in advancing stroke care.

The Undiagnosed Diseases Network (UDN) aims to enhance diagnostic excellence through multiple clinical Networks of Diagnostic Excellence (NODEs). These NODEs will operate as regional networks, leveraging partnerships with various healthcare facilities to provide participant-centered evaluations for complex conditions. They will also engage in research and training to improve diagnostic tools and strategies. This initiative encourages collaboration and aims to improve the overall experience and access for participants in need of specialized care.

The National Institutes of Health (NIH) is continuing its support for the NeuroNEXT initiative, which focuses on conducting clinical trials and biomarker validation studies for neurological disorders. This infrastructure aims to foster innovation and enhance the development of effective neurotherapeutics for both adult and pediatric populations. While applications for network clinical research sites are not currently being solicited, this notice allows potential applicants to prepare collaborative and responsive applications.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

The Native Public Health Resilience (NPHR) program is a new funding opportunity aimed at supporting Tribes and Tribal Organizations in delivering essential public health services. Sponsored by the Indian Health Service, this initiative seeks to bolster public health infrastructure and resilience within tribal communities, ensuring they have the necessary resources to address health challenges effectively. Eligible applicants will receive financial assistance to enhance their public health capabilities and improve community health outcomes.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment and recovery through a robust national infrastructure. Funded by the National Institutes of Health, this initiative focuses on clinical trials that evaluate innovative therapies for stroke patients and those at risk. The program is currently not soliciting applications but encourages the development of collaborations to support the national coordinating center and data management efforts, ultimately improving outcomes for individuals affected by stroke.

The NIDA Avenir Program aims to cultivate innovative leaders in addiction science by funding exceptional early stage investigators (ESIs) embarking on pioneering research. Launched in 2015, this initiative encourages high-risk, high-reward mechanistic studies related to Substance Use Disorders (SUDs) across diverse scientific domains. Applications from new investigators and those outside addiction research are welcomed, fostering interdisciplinary approaches that enhance understanding of SUD mechanisms. The program supports ESIs who may lack preliminary data but demonstrate potential for impactful contributions.

The BRAIN Initiative aims to advance innovative neurotechnologies by funding early-stage clinical studies for devices that record or stimulate the human central nervous system. This initiative encourages collaborations between clinical researchers and device manufacturers to facilitate groundbreaking studies. By addressing the challenges of obtaining safety and utility data, this program supports both non-invasive and significant risk devices, providing essential insights into their functionality and design. Applications are currently not being solicited, allowing time for meaningful project development.

The BRAIN Initiative, led by the NIH, aims to advance neurotechnologies at institutions with limited NIH funding. This funding opportunity encourages collaboration and knowledge transfer to integrate innovative neurotechnologies into research and training programs. While applications are currently not being solicited, potential applicants should start developing partnerships and projects in preparation for future submissions. This initiative will enhance the dissemination of BRAIN technologies and support novel research practices.

Stars, Stripes & Skilled Trades

General Motors invites eligible 501(c)(3) nonprofit organizations to submit proposals for Stars, Stripes & Skilled Trades, a workforce development initiative designed to support veterans, transitioning service members, and military-connected family members—including spouses—in building lasting careers in manufacturing, automotive, and skilled trades. GM is seeking scalable, results-driven programs that create clear pathways to quality careers while recognizing the experience and leadership that veterans and military families bring to American industry. 

We're looking for existing initiatives that:

• Serve career-transitioning service members, veterans, and military-connected family members
• Provide industry-recognized training, certifications, or credentials
• Connect participants to mentorships, quality jobs, and long-term career pathways in manufacturing, automotive technician roles, or skilled trades.

Grant Range

• $100,000 | $250,000 | $500,000

Mellon Foundation

The Andrew W. Mellon Foundation was established in 1969 to strengthen, promote, and defend the arts and humanities as essential to democratic societies. Throughout our history, Mellon has held true to our founding commitments, secure in our conviction that the arts and humanities are essential to the health of a multivocal and democratic society. From our earliest days, we have aspired to build partnerships with our grantees, offering expertise and counsel in addition to funding

In recent years, Mellon has expanded on these core principles by actively prioritizing social justice across all of our grantmaking. This strategic shift builds on our long history of advocating for and investing in expanded access to higher education, humanities, and the arts, and addressing historical inequities in these fields. Our vision for Mellon’s future includes a focus on justice for all in all that we do—rooted in the Foundation’s long-held historic belief in the impact and power of the arts and humanities. At Mellon, we make grants to actively support communities and ideas that unlock the power in the arts and humanities that helps connect us all.

Humanities in Place Grant Program

The Andrew W. Mellon Foundation actively works with our grantee partners and we are deeply immersed in the fields in which we invest. Our grants are designed to activate the spirit of learning through the creation and sharing of bold new ideas and the inspiration felt in art, expression, spaces, and scholarship. 

From Alaska to Guam and the Borderlands to the Midwest, America is a constellation of unique heritages, traditions, and stories. In communities of all sizes, people are striving to expand the ways we can understand and authentically engage with the history that is all around us. Our Humanities in Place grants fund place keepers, artists, institutions, and storytellers who shine a spotlight on historically overlooked sites, and the communities and stories that surround them. In doing so, they help broaden our shared understanding and open new paths to discover what unites us, what makes us unique, and what we can learn from one another.

Company culture at Clark Associates emphasizes responsibility, sharing our success with others, and the importance of building strong communities. To help fulfill these goals, Clark Associates Charitable Foundation (CACF) was incorporated in 2001 and provides funding to organizations serving people in need and those delivering positive experiences for youth. CACF supports non-profits operating in and around its business locations and those where our employees volunteer and actively contribute. To date, CACF has distributed over $44 million in charitable contributions.

Organizations must be registered 501c3 charities serving three basic categories: people in need, innovative youth educational programs, and youth programs in music and the arts. People in need represents the largest giving category and includes homelessness, food insecurity, individuals with disabilities, victims of abuse, and people in recovery. Examples of other grant recipients include those assisting veterans, senior citizens, at-risk youth, academic enrichment, mentorship, leadership development, and those focused on the performing and visual arts.CACF evaluates grant applications submitted by non-profit organizations every month of the year.