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Best Berkeley County Grants for Nonprofits in South Carolina

Discover active funding opportunities in Berkeley County Grants for Nonprofits. 37,000+ grants are available for a wide range of missions and programs with additional grants in Charleston County, Dorchester County, and Georgetown County.

9,000+

Available grants

$3.79B

Total funding

$5K

Median grant

9,000+ grants
$3.79B total
$5K median

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9,135 Results based on applied filters

Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) is collaborating with other NIH institutes to enhance rigor and replicability in biomedical and behavioral research. This initiative aims to support projects focused on assessing the impact of improved research practices, developing frameworks for study selection, and measuring the generalizability of findings. Currently, applications are not being solicited, allowing researchers time to prepare collaborative proposals.
Neurological Diseases & Disorders

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

Fellowship in Anthropology and Black Experiences

Wenner-Gren Foundation
Private
Countries
US $80,000

About Us

The Wenner-Gren Foundation is a private operating foundation dedicated to providing leadership in support of anthropology and anthropologists worldwide.

Our Mission

The Wenner-Gren Foundation is committed to playing a leadership role in anthropology. We help anthropologists advance anthropological knowledge, build sustainable careers, and amplify the impact of anthropology within the wider world. We dedicate ourselves to broadening the conversation in anthropology to reflect the full diversity of the field.

Fellowship in Anthropology and Black Experiences

General

This writing fellowship expands anthropological conversations and builds capacity in anthropology, both as a career and a field of study, by amplifying perspectives previously underrepresented in the discipline. The Fellowship in Anthropology and Black Experiences supports individuals whose research draws on Black studies, critical race studies, diasporic Africana studies, the vernacular insights of communities of color, and other sources of inspiration growing out of global Black experiences, to advance new lines of scholarship in any of anthropology’s subfields. We hope to attract applicants working in diverse areas, including but not limited to Black communities.

Applicants should show how the Fellowship would enable them to succeed at a critical juncture in their career, alter their trajectory in the field, and enable them to reach new networks and audiences within and beyond anthropology. 

As part of the 9-month fellowship, the Fellow will join a cohort of awardees and benefit from workshops and mentoring events designed to help them amplify their writing project’s impact within the public sphere.

Award Money

Fellows receive a stipend of $80,000 over 9 months. You are welcome to request the funds be paid directly to you or through an affiliated institution. 

Archaeology Biological Anthropology Anthropology & Cultural Studies +2 more

Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $100,000 - US $500,000
This funding opportunity from the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to advance mechanistic research on metal exposure and its effects on human health. Studies should focus on biological processes altered by metals, including their absorption, transport, and immune interactions. Innovative methodologies and human biospecimens are encouraged to explore how metals might impact immune homeostasis and cross biological barriers, providing insights into health risks associated with metal exposure.
Biology Environmental Contamination & Pollution Neurological Diseases & Disorders +1 more

Limited Competition: Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The TURTLE Program aims to empower Tribal Entities by fostering a skilled workforce in biomedical research. It supports undergraduate and graduate students in health research, ensuring they complete their degrees and transition into impactful careers. With phased awards, the program emphasizes effective training and mentoring, inviting eligible organizations to apply. Applications will undergo NIH's peer-review process, ensuring only the most meritorious proposals are funded, ultimately enhancing Tribal health research capabilities.
Education - Higher Education Workforce Preparation & Job Readiness Native American Services +1 more

Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Unspecified amount
The TIRBEE funding opportunity supports federally-recognized Tribes and Tribal Entities in establishing or enhancing Institutional Review Boards. This initiative aims to strengthen the capacity for biomedical research involving human participants within these communities by improving review and oversight capabilities. Eligible organizations are invited to apply, with applications subject to NIH's standard peer-review process to ensure only the most meritorious proposals are considered.
Epidemiology & Public Health Native American Services Health Disparities & Social Determinants of Health +1 more

Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (R24 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance our understanding of somatic mutations and their impact on human biology and disease. This initiative will establish a Tissue Procurement Center (TPC) to collect and provide clinically relevant tissue samples from a diverse set of healthy donors. The TPC will support ongoing research by ensuring high-quality, well-characterized specimens are available for functional analyses, advancing the field of somatic mosaicism.
Biology Genetics & Genomics

Somatic Mosaicism across Human Tissues (SMaHT) Program: National Somatic Mosaicism Commons Data Analysis & Organizational Center (UM1 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to enhance understanding of biological processes and disease mechanisms due to somatic mutations in human tissues. Since 2023, it has produced multi-omic datasets from various human tissues. The NIH plans to advance this initiative by establishing the National Somatic Mosaicism Commons Data Analysis & Organizational Center, which will oversee data management, develop analytical tools, and provide training to facilitate research and clinical applications.
Genetics & Genomics Computer Science & Engineering Emerging Technology Development

Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed) (363858)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Somatic Mosaicism across Human Tissues (SMaHT) Program aims to uncover biological processes and disease mechanisms influenced by somatic mutations. Since its inception in 2023, it has produced valuable multi-omic datasets from diverse human tissues. The upcoming Stage 2 Genome Characterization Centers will focus on understanding the impact of these mutations in both healthy and clinically significant samples, enhancing our knowledge of somatic mosaicism's role in human health and disease.
Biology Genetics & Genomics

A Year of STEM

American Library Association (ALA)
Association/Society
United States
US $5,000

In collaboration with Cummins Inc., the American Library Association (ALA) invites applications from U.S. public libraries to participate in A Year of STEM, 12 months of curated STEM programming to foster curiosity and STEM-mindedness in early childhood learners across the country. 

Twenty-five libraries will be chosen to participate in A Year of STEM, receiving professional development to prepare them for the project, copies of a newly created A Year of STEM programming guide developed by librarian advisors, a $5,000 programming stipend, four STEM kits (to be delivered quarterly), and support from ALA’s Public Programs Office staff throughout the project implementation period.

STEM / STEAM Education Library Services

The Penn Play Award

LR Penn
Corporate
United States
Unspecified amount

LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.  

Theater

Technology Development Program

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Technology Development Program by the US Department of Health & Human Services focuses on advancing technology research from proof-of-concept to prototype development. This initiative prioritizes innovation to enhance biomedical research, emphasizing technological improvements without the inclusion of biological hypothesis testing. Eligible projects should aim at significant technological advancements to maximize impact in the field.
Engineering Science Emerging Technology Development

Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $190,000 - US $500,000
The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.
Biology Health & Medicine Emerging Technology Development

FY2026/2027 Community Compass Technical Assistance and Capacity Building Program Notice of Funding Opportunity

US HUD: Office of Community Planning and Development (CPD)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $35,000,000
The FY2026/2027 Community Compass Technical Assistance and Capacity Building Program provides competitive grants to organizations capable of delivering technical assistance (TA) to communities served by HUD. With up to $86 million available, recipients are expected to develop educational tools, collaborate with HUD, and show a strong record of performance. This initiative aims to enhance community systems, support high-priority projects, and ensure effective training delivery, fostering impactful outcomes across the nation.
Community Services Nonprofit Growth & Development

Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.
Mental Health & Psychiatric Diseases Health Care Access & Delivery

Landmarks of History and Culture and Summer Institutes

National Endowment for the Humanities
Federal Government
American Samoa, Guam +4 more
Up to US $460,000
The National Endowment for the Humanities invites K-12 teachers and higher education faculty to apply for the Landmarks of American History and Culture and Summer Institutes program. This initiative aims to enhance humanities education through professional development opportunities, fostering a deeper understanding of historical and cultural landmarks. Participants will engage in enriching experiences designed to improve teaching practices and student learning outcomes in the humanities.
Humanities & Social Science Community Culture & Heritage Teacher Development & Training

Relentless Challenge Grants

The South Carolina Department of Commerce (S.C. Commerce)
State/Local Government
South Carolina
US $50,000 - US $75,000

Relentless Challenge Grants

The Relentless Challenge is a statewide competitive grant program and is South Carolina’s call to action for innovative problem-solving and entrepreneurial impact. Aligned with the Launch to Legacy brand, S.C. Commerce’s vision to support businesses at every stage and position the state as the new home for American innovation, the 2026 Relentless Challenge supports two complementary tracks: traditional small business and innovation.

While distinct in focus, both tracks share a common thread: empowering South Carolina’s businesses to launch, grow and innovate for long-term success. Traditional small businesses form the backbone of local economies and play a vital role in sustained economic growth. Innovation-driven companies, whether new or well-established, contribute to future advancement through R&D and product innovation. Together, they create a balanced ecosystem where stability and disruption coexist, enabling businesses to thrive and fueling statewide prosperity.

Track One: Traditional Small Business

Every business has the potential to innovate. This track funds creative, actionable solutions to the challenges facing South Carolina’s traditional small businesses. The goal is to spark the development of new ventures, strengthen existing ones, and improve access to capital through targeted funding and financial education resources — ultimately helping traditional small businesses grow, flourish, and contribute to the state’s economic vitality.

Track Two: Innovation

Designed to advance South Carolina’s innovation economy, this track supports projects that foster a resilient ecosystem for innovation. Emphasis is specifically placed on catalyzing high-growth entrepreneurship, expanding access to risk capital, and deepening collaboration between higher education institutions and companies of all sizes — laying the foundation for next-generation industries and long-term economic impact.

Business Education Business Development

Ski Racing Safety Equipment Grant

Kelly S Brush Foundation
Private
United States
Unspecified amount

KBF Ski Racing Safety

The KBF helps alpine ski clubs around the country purchase safety equipment like netting and padding, and also contributes to venue improvement initiatives. Funding requests are reviewed through an annual grant cycle with an application process. Over the past decade, the Kelly Brush Foundation has purchased thousands of rolls of b-netting, supported trail widening projects, and helped with the purchase of other safety equipment. 

KBF Ski Racing Safety Equipment Grants are all matching grants–meaning that any grant awarded by the Kelly Brush Foundation will need to be matched by the ski club. We expect that clubs will join us in making safety a priority by fundraising or finding room in their budget for safety.

Snow Sports

BJA FY 2026 Second Chance Act Community-based Reentry Program

US DOJ: OJP Bureau of Justice Assistance
Federal Government
United States
Up to US $1,000,000
The BJA FY 2026 Second Chance Act Community-based Reentry Program aims to support community organizations and tribal governments in providing essential mentoring and transitional services for individuals returning from correctional facilities. This initiative targets those assessed as moderate to high risk for recidivism, addressing their needs both pre-and post-release. By fostering successful reintegration into society, the program contributes to public safety and reduces recidivism rates, aligning with the mission of the U.S. Department of Justice.
Crime & Justice Reentry Services Employment Services +2 more

OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $1,200,000
The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.
Youth Services Crime & Justice Crime Victim Services +1 more

Strengthening Collaboration Between Tuberculosis Control Programs and Affiliated Partners in the United States.

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +7 more
Unspecified amount
The CDC is offering funding to enhance collaboration among tuberculosis control programs and various partners in the U.S. This initiative aims to strengthen relationships with national TB control entities, federal agencies, academia, and community organizations. The goal is to promote health and quality of life by preventing, controlling, and eventually eliminating tuberculosis in the United States, building on previous funding opportunities.
Epidemiology & Public Health Infectious & Parasitic Diseases Preventative Healthcare +1 more

Advanced Rehabilitation Research Training (ARRT) Program - Employment (363964)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program aims to enhance the research capabilities of individuals with advanced degrees, focusing on disability and rehabilitation research related to employment outcomes. Funded by the US HHS Administration for Community Living, this grant offers a 36-month project period, supporting multidisciplinary training for researchers, including those with disabilities, to contribute to high-quality research in the field.
Disability Care & Services Medical Rehabilitation Employment Services +1 more

Advanced Rehabilitation Research Training (ARRT) Program - Health and Function (363965)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.
Medical Rehabilitation Medical Education & Professional Training Disability Rights & Justice

Small Business Innovation Research Program (SBIR) Phase II (363967)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $280,000 - US $287,500
The Small Business Innovation Research Program (SBIR) Phase II aims to enhance technological innovation in the private sector, focusing on improving the lives of individuals with disabilities through research and development. Administered by the US HHS Administration for Community Living, this program supports small businesses in addressing the needs of these individuals. Grants are available for a 24-month project period, allowing projects to expand upon Phase I results to achieve greater commercial application and societal impact.
Disability Care & Services Medical Rehabilitation Emerging Technology Development +1 more

Small Business Innovation Research (SBIR) program, Phase I (363966)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $95,000 - US $100,000
The Small Business Innovation Research (SBIR) program, Phase I, aims to stimulate technological innovation in the private sector, enhancing the role of small businesses in meeting Federal research needs. Specifically, ACL's SBIR program focuses on improving the lives of individuals with disabilities through research and development products. The initiative includes 11 grants with a 6-month project period to assess the feasibility of innovative concepts, contributing to economic and social benefits.
Disability Care & Services Emerging Technology Development Business Development

Advanced Rehabilitation Research Training (ARRT) Program - Community Living and Participation (363963)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the skills of researchers in the field of disability and rehabilitation. By providing advanced training over a three-year period, this program focuses on improving community living and participation outcomes for individuals with disabilities. It seeks to equip scholars with the necessary tools to conduct high-quality, multidisciplinary research, ultimately benefiting the disability community.
Disability Care & Services Medical Rehabilitation Medical Education & Professional Training

Berkeley County Grants for Nonprofits Highlights

Looking for Berkeley County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Berkeley County grants recommended for your specific programs in South Carolina.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Berkeley County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Berkeley County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Berkeley County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081