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Best Colleton County Grants for Nonprofits in South Carolina

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Causal Research on the Impacts of K‑12 School Policies RFP

Arnold Ventures
Private
United States
Unspecified amount

Arnold Ventures

Overview

Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of Americans through evidence-based policy solutions that maximize opportunity and minimize injustice. We focus on improving systems where outcomes are falling short, incentives are misaligned, and the time is right for change.

To advance this mission, we invest in rigorous research to better understand the root causes of problems and strengthen the evidence base on what works to solve them. Using this evidence, we advocate for policy reforms and help build durable, bipartisan coalitions for lasting change.

Request for Proposals

Causal Research on the Impacts of K-12 School Policies 

The next several years present an important opportunity to shape the future of state K-12 education policy. States are making consequential decisions about curriculum, assessment, and accountability systems; school choice and governance policies; and teacher and leader workforce policies. High-quality research in these areas will help policymakers distinguish between reforms that are merely appealing and those that meaningfully improve student outcomes over the long term.

Through this request for proposals (RFP), Arnold Ventures seeks to support research studies that estimate the causal effects of actionable, politically viable U.S. K-12 education policies that can be influenced at the state level and have the potential to improve outcomes at scale. Competitive proposals should employ rigorous causal research methods and, where feasible, examine not only short-term educational outcomes but also longer-term impacts on postsecondary and/or labor market outcomes using administrative data. Given the pace of state policymaking, we place a high value on research that can inform decisions quickly and will give preference to studies that can be completed within 18 months of project kickoff and/or produce actionable findings by the end of 2028.

Education - K through 12 Education System Policy & Reform

Fall 2026 Early Childhood Education Grant

Stranahan Foundation
Private
United States
Up to US $150,000

Fall 2026 Early Childhood Education Funding Cycle

Overall Early Childhood Education Program Blueprint

The Stranahan Foundation’s Early Childhood Education grant program supports efforts to improve access to high-quality early care and education for young children (birth to five), especially those from low-income families. We do this by investing in strategies that strengthen, support, and retain a high-quality, thriving early educator workforce.

The Foundation has a history of supporting professional development (PD) and learning systems through its Provider strategy (). We believe strong professional development systems are essential for building a skilled early childhood workforce and creating positive learning environments for young children.

The Fall 2026 funding cycle is available for organizations that align with this Provider strategy.

Funding Opportunity

This funding opportunity will provide up to $750,000 to support early childhood education providers in strengthening existing professional development (PD) systems. Funding is intended to improve a specific area of an established PD system—not to build a brand-new system from scratch or put the foundational elements in place.

What kind of improvements can funding support?

Organizations should focus their projects on strengthening their professional development systems. The Stranahan Foundation defines a strong professional development system as one that includes:

  • Connect learning opportunities that build on one another over time.
  • Use adult learning best practices.
  • Align staff learning to educator competencies, credentials, career growth, or compensation.
  • Provide learning experiences that are individualized, scaffolded, and responsive to educators’ needs, experience, and goals.
  • Have dedicated leadership and organizational capacity to support ongoing implementation.

  • Gather regular feedback from staff and families.
  • Use standardized assessment and evaluation tools to understand what is working and where improvements are needed.
  • Make ongoing improvements based on what is learned.
  • Support reflective practice, peer learning, and collaborative inquiry among educators.

  • Offer both individual and group learning opportunities, such as training, professional learning communities, coaching, and mentoring.
  • Provide learning opportunities on an ongoing basis rather than in a one-and-done situation.
  • Connect internal and external learning opportunities to make the best use of available resources.
  • Support classroom implementation through observation, modeling, feedback, and continuous improvement cycles.

  • Provide learning experiences that are practical, relevant, and easy to apply in daily work.
  • Include fundamental topics such as family engagement, effective instruction, developmentally appropriate practice, and classroom management.
  • Align with established standards, research, and effective practices in the early childhood field.
  • Equip educators to support all learners, including multilingual learners, children with disabilities, and children impacted by trauma or adverse experiences.
Education - Preschool / Early Learning Workforce Preparation & Job Readiness Early Childhood Development +1 more

Sawyer Foundation Grant

Sawyer Foundation Charitable Tr
Private
United States
US $1,000 - US $25,000

About Sawyer Foundation Charitable Trust Our mission is to support partner organizations that share the gift of clean drinking water to under-resourced communities. Our vision is to see all of our global community have access to clean, safe drinking water.Through our partnership with Sawyer, our nonprofit partners have access to affordable, point-of-use filters designed to provide reliable access to clean water for 10+ years.‍

Sawyer partners with over 140 non-profits in more than 100 countries, providing clean water to families lacking access to clean water – for long-term relief and in disaster situations.About Sawyer Foundation Grant We prioritize projects that demonstrate a strong commitment to:

  • Long-term sustainability in water filtration and access.
  • Training, follow-up, and local engagement that strengthen best practices.
  • Data collection or research that improves project implementation and outcomes.
  • Unique expertise, partnerships, or approaches that enhance global impact.
Sanitation & Clean Drinking Water

Dairy Business Innovation Initiatives Program (DBI) Fiscal Year 2026

USDA: Agricultural Marketing Service (AMS)
Federal Government
United States
US $2,300,000 - US $3,450,000
The Dairy Business Innovation Initiatives Program (DBI) for Fiscal Year 2026, administered by the USDA's Agricultural Marketing Service, invites applications from existing initiatives to support the dairy industry. With approximately $12.65 million available, the program aims to diversify dairy markets, enhance farmer income, and promote regional milk production. Funding will prioritize equipment and infrastructure projects, which are vital for strengthening the capacity of dairy businesses and fostering innovation in processing and marketing.
Agriculture Agricultural Economics Business Development

WATER RESOURCES RESEARCH ACT PROGRAM NATIONAL COMPETITIVE GRANTS FY2026 (104g General)

US Department of the Interior: Geological Survey (USGS)
Federal Government
American Samoa, Guam +5 more
Up to US $120,000
The Water Resources Research Act Program National Competitive Grants FY2026, administered by the U.S. Geological Survey, aims to support innovative research initiatives at Water Resources Research Institutes across the U.S. and its territories. These grants facilitate essential studies on water management, addressing critical water resource challenges while promoting collaboration among states. This program seeks to enhance the understanding of water issues, ultimately contributing to sustainable management practices and informed decision-making in water resource policy.
Hydrology Freshwater Conservation Environmental Policy

Fiscal Year 2026 Wildlife Crossings Pilot Program

DOT Federal Highway Administration
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2026 Wildlife Crossings Pilot Program aims to enhance public safety by reducing wildlife-vehicle collisions and improving habitat connectivity for various species. With approximately $80 million available through cost reimbursable grants, this initiative supports eligible projects that address these critical environmental and safety concerns. The program may also distribute leftover funds from previous years, contingent on availability, fostering innovative solutions in wildlife management and transportation safety.
Land / Habitat Conservation Community / Public Safety Wildlife Health +1 more

The Science, Mathematics and Research for Transformation (SMART) Scholarship for Service Program Cooperative Agreement

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $1,300,000,000
The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.
Education - Higher Education Workforce Preparation & Job Readiness STEM / STEAM Education

GAP Audit Reimbursement Cost Share

South Carolina Department of Agriculture
State/Local Government
South Carolina
Unspecified amount

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

GAP Audit Reimbursement Cost Share

Through funding from the USDA AMS Specialty Crop Block Grant Program (#25SCBPSC1280), South Carolina growers can now get reimbursed for 90% of the costs associated with a GAP audit completed while funds are available. To help growers receive reimbursements faster, they may choose to receive two separate payments. A grower may submit Part I of the application as soon as they have paid the SCDA portion of the audit without having to wait on the USDA invoice. Then, once the grower has paid the USDA portion, they may submit Part II of the application to receive 90% of that amount as well. However, a grower may choose instead to submit both parts together to receive one larger payment. See examples below:

Example 1

Smith Farm submits a paid receipt from SCDA Fruit & Vegetable Inspections for $575 with Part I of the application and receives a check for $517.50 approximately four weeks later. ($575 × 90%)

Next, the Smiths receive the USDA invoice, pay $345 to USDA, then submit the paid receipt with Part II of the application to USDA. About four weeks later the Smiths receive a second check for $310.50. ($345 × 90%)

Example 2

Jones Farm is charged the same as the Smiths above but chooses to wait until they have paid both invoices to submit the application. In this case, they may submit both Parts I and II of the application at the same time. The Jones’ will receive one check approximately four weeks later for $828.

($575 + $345 = $920 × 90%)

Applicants must submit a complete application package including all of the following:

  • Completed application with correct information
  • A state vendor registration number
  • Complete, detailed answers to the questionnaire included in the application (Note: This information impacts our ability to seek continued funding for this program).
  • Your agreement to provide follow-up information regarding the impact of GAP certification (Note: This information impacts our ability to seek continued funding for this program).
  • A copy of the paid receipt or other proof of payment for the reimbursement you are requesting. We will not send checks unless we have this.
Agricultural Crops

Cold Storage Cost Share Program

South Carolina Department of Agriculture
State/Local Government
South Carolina
Up to US $750

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Cold Storage Cost Share Program

The South Carolina Department of Agriculture and South Carolina Specialty Crop Growers Association are pleased to announce continued funding for the Cold Storage Cost Share Program. Through the USDA Specialty Crop Block Grant Program, farmers who are members of the South Carolina Specialty Crop Growers Association may receive reimbursement up to $750 for the purchasing and installing up to two (2) Cool Bot cooler systems. Nonmembers may receive reimbursement up to $325, for installing one (1) Cool Bot cooler system. The Cool-Bot utilizes a traditional window-unit air conditioner, multiple sensors, a heating element, and a programmed micro-controller to direct your air conditioner’s compressor to cool the room to 36° F, without ever freezing up.

Agricultural Crops

Market Development Educational Conference Cost Share Program

South Carolina Department of Agriculture
State/Local Government
South Carolina
Unspecified amount

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Market Development Educational Conference Cost Share Program

The SC Specialty Crop Growers Association is partnering with the SC Department of Agriculture (SCDA) to promote the specialty crop industry through a cost share program that will assist growers in attending domestic industry trade show and educational conferences. Attendance at various trade shows and conferences will equip South Carolina’s specialty crop growers with the latest and most current research based educational information on topics such as pest management, sustainability, production practices, food safety, and regulatory issues, which are essential in expanding the specialty crop industry.

Through funding from the USDA Specialty Crop Block Grant, this cost share program will cover 50% of registration fees for attending a specialty crop-focused educational conference for up to 2 growers per company. The cost share will not cover costs of merchandise, travel, food, or lodging.

Reimbursements are available on a first come first serve basis until funds are depleted. A farm may submit their application and primary source receipts after each event or following the end of the conference season.

Graduation Rule

Growers cannot exceed more than two consecutive years in the program, although they can reapply after one year hiatus.

Agricultural Crops

Academic Matching Grant

South Carolina Research Authority
Private
South Carolina
US $5,000 - US $15,000

South Carolina Research Authority

SCRA is a public, non-profit corporation chartered in 1983 by the State of South Carolina. Its mission is to fuel South Carolina’s innovation economy by accelerating technology-enabled growth of academia, entrepreneurship, and industry. SCRA's vision is focused in becoming a leading catalyst in making South Carolina the top choice for technology-focused industry, entrepreneurs, investors, and academics.

SCRA supports its stakeholders in key technology sectors, which include but are not limited to, Advanced Materials/ Manufacturing; Life Sciences; Clean Tech, Sustainability, and Resilience, and Information Technology. SCRA grant funding is made possible, in part, by Industry Partnership Fund (IPF) contributions. Contributors receive a dollar-for-dollar South Carolina income tax credit, making it a no-cost way to create a direct, positive economic effect and job creation. 

Academic Matching Grant 

Managed by the Academic Innovations team, the objective of the Academic Matching Grant is to expand academic engagement in research and development by validating and advancing technology concepts towards the potential of a license opportunity, and/or company formation. Key milestones include: market opportunity and technical feasibility, in the IDEATION stage of startup development. 

Qualifying technologies are recommended by the institution’s Technology Transfer Office, or equivalent; Institutions are responsible for the technical review and prioritization of applications, and review opportunities with the Academic Innovations team. Based upon the review, SCRA will provide application materials and instructions. 

Academic Success & Enrichment Emerging Technology Development

Small Business Innovation Research and Small Business Technology Transfer Programs Phase II (364020)

USDA: National Institute of Food and Agriculture (NIFA)
Federal Government
American Samoa, Guam +4 more
US $600,000 - US $650,000
The USDA SBIR/STTR programs aim to enhance scientific excellence and technological innovation through federal funding, fostering a robust national economy. By supporting small businesses in addressing federal research needs, these programs encourage the commercialization of federally funded research. Specifically, the STTR program promotes partnerships between small businesses and research institutions, such as universities and federal laboratories, to advance cooperative research and development efforts.
Entrepreneurship Economic Services & Development Emerging Technology Development +1 more

Technical Assistance and Training Grant Program (364019)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.
Rural Development Public Infrastructure Fish Conservation

Solid Waste Management Grant Program (364018)

USDA: Rural Utilities Service (RUS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.
Freshwater Conservation Environmental Contamination & Pollution Environmental Health +1 more

HIV Prevention and Alcohol (R61/R33 Clinical Trials Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.
Infectious & Parasitic Diseases HIV / AIDS Preventative Healthcare

ROSES 2025: A.18 Geosphere

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NASA ROSES 2025: A.18 Geosphere program provides funding for research on solid-Earth processes across various scales. It aims to enhance understanding of the Earth's structure and dynamics, particularly in the core, mantle, and lithosphere. Key areas of focus include Earth Surface Properties, Crustal Dynamics, and Earth Interior. This initiative supports advancements in managing natural resources, assessing geohazards, and exploring the forces driving plate tectonics, ultimately contributing to improved hazard forecasting and mitigation strategies.
Earth Science Geology Disaster Preparedness

Distressed Cities Technical Assistance (DCTA) Program for Fiscal Years 2026 and 2027

US HUD: Office of Community Planning and Development (CPD)
Federal Government
American Samoa, Guam +4 more
US $400,000 - US $3,000,000
The Distressed Cities Technical Assistance (DCTA) Program provides competitive funding for eligible applicants to deliver technical assistance to local governments serving economically distressed communities of 50,000 or fewer residents. Selected awardees collaborate closely with HUD to enhance the capabilities of UGLG officials and staff, ensuring they effectively address community needs. Applicants may focus on broad HUD jurisdictions or specific areas as specified in the program's NOFO.
Economic Services & Development Community Development & Revitalization Rural Development

Unlocking Value and Opportunities from Carbon Flows in Water Utilities RFP

Water Research Foundation
Private
Canada, United States
Up to US $300,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5430 - Unlocking Value and Opportunities from Carbon Flows in Water Utilities

Grant Information

  • Identify carbon flows across drinking water, stormwater, wastewater, and advanced treatment systems. Carbon flows may include source water, stormwater, process emissions, process inputs, residuals, and biogas.
  • Identify the most relevant carbon recovery, capture, conversion, storage, and avoidance opportunities.
  • Evaluate value creation pathways, including products, avoided costs, and environmental attributes, and mechanisms and partnerships needed to put them into practice.
  • Assess how opportunities vary across system types and local contexts by focusing on more common scenarios for utilities.
  • Provide practical, research-based insights to support identification, prioritization, evaluation, and advancement of carbon management opportunities under site-specific conditions and constraints.
  • Evaluate implications for greenhouse gas (GHG) accounting, environmental attribute claims, and other potential benefits across pathways.
Water Resource Management Carbon / Greenhouse Gas Reduction Green Infrastructure

Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5411 - Practical Playbook for Adaptive Utility Capital Improvement Planning Under Deep Uncertainty

Grant Information

  • Assess current utility practices for incorporating adaptive or flexible decision making into capital improvement planning (CIP) at the portfolio or programmatic level.
  • Identify where deep uncertainty most affects CIP decision points, including investment areas prone to lock-in or points of no return.
  • Document the institutional processes, frameworks, and governance structures that have enabled utilities to embed adaptive and flexible investment strategies.
  • Quantify how adaptive capital strategies compare to traditional CIP approaches in terms of lifecycle costs, rate stability, financial risk exposure, and avoided or deferred capital investments across a range of plausible future conditions.
  • Establish practical criteria to help utilities determine which types of capital investments are well suited for adaptive approaches.
  • Develop a practitioner-focused playbook that equips utilities to apply adaptive CIP in practice, including case studies, decision trees, trigger points, vulnerability assessment tools, financial and risk insights, and governance guidance.
  • Produce tiered recommendations that allow utilities to adopt adaptive CIP practices incrementally.
Water Resource Management Environmental Policy

Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits RFP

Water Research Foundation
Private
Countries
Up to US $450,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5418 - Optimizing PFAS Treatment Systems for Multi-contaminant Removal and Operational Benefits

Project Objectives

Environmental Contamination & Pollution Water Resource Management Carbon / Greenhouse Gas Reduction

Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies RFP

Water Research Foundation
Private
Countries
Up to US $250,000

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

5426 - Investigation of Non-Point Sources of PFAS in Sewersheds and Potential Mitigation Strategies

Grant Information

  • Evaluate the impact of non-point or dispersed sources of per- and polyfluoroalkyl substances (PFAS) in the sewershed (including PFAS-contaminated groundwater infiltration) on PFAS mass loading to wastewater treatment plants.
  • Assess how PFAS loading from non-point or dispersed sources of PFAS in the sewershed may affect treatment efficiency and reuse water quality.
  • Improve understanding of PFAS precursor contributions.
  • Identify potential strategies to mitigate PFAS loading from non-point or disbursed sources of PFAS in the sewershed.
  • Water Resource Management Sanitation & Clean Drinking Water

    A Year of STEM

    American Library Association (ALA)
    Association/Society
    United States
    US $5,000

    In collaboration with Cummins Inc., the American Library Association (ALA) invites applications from U.S. public libraries to participate in A Year of STEM, 12 months of curated STEM programming to foster curiosity and STEM-mindedness in early childhood learners across the country. 

    Twenty-five libraries will be chosen to participate in A Year of STEM, receiving professional development to prepare them for the project, copies of a newly created A Year of STEM programming guide developed by librarian advisors, a $5,000 programming stipend, four STEM kits (to be delivered quarterly), and support from ALA’s Public Programs Office staff throughout the project implementation period.

    STEM / STEAM Education Library Services

    The Penn Play Award

    LR Penn
    Corporate
    United States
    Unspecified amount

    LRPenn.com is home to the novels, plays, and screenplays of LR Penn. His books specializes in Thrillers, Dramatic Comedies, and Film Noir. Thanks to the generous support of our sponsors, grants may be available to nonprofit theater companies in the United States with 501(c)(3) status that are staging productions of plays written by LR Penn.  

    Theater

    Technology Development Program

    US Dept. of Health & Human Services: National Institutes of Health (NIH)
    Federal Government
    American Samoa, Guam +4 more
    Unspecified amount
    The Technology Development Program by the US Department of Health & Human Services focuses on advancing technology research from proof-of-concept to prototype development. This initiative prioritizes innovation to enhance biomedical research, emphasizing technological improvements without the inclusion of biological hypothesis testing. Eligible projects should aim at significant technological advancements to maximize impact in the field.
    Engineering Science Emerging Technology Development

    Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

    US Dept. of Health & Human Services: National Institutes of Health (NIH)
    Federal Government
    American Samoa, Guam +4 more
    US $190,000 - US $500,000
    The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.
    Biology Health & Medicine Emerging Technology Development

    FY2026/2027 Community Compass Technical Assistance and Capacity Building Program Notice of Funding Opportunity

    US HUD: Office of Community Planning and Development (CPD)
    Federal Government
    American Samoa, Guam +4 more
    US $250,000 - US $35,000,000
    The FY2026/2027 Community Compass Technical Assistance and Capacity Building Program provides competitive grants to organizations capable of delivering technical assistance (TA) to communities served by HUD. With up to $86 million available, recipients are expected to develop educational tools, collaborate with HUD, and show a strong record of performance. This initiative aims to enhance community systems, support high-priority projects, and ensure effective training delivery, fostering impactful outcomes across the nation.
    Community Services Nonprofit Growth & Development

    Advancing Real-World Effectiveness Evidence for Rapid-Acting Psychotropic Interventional Drugs (RAPIDs)

    US Dept. of Health & Human Services: National Institutes of Health (NIH)
    Federal Government
    American Samoa, Guam +4 more
    Unspecified amount
    The National Institute of Mental Health (NIMH) is launching a funding opportunity to establish a research network focused on rapid-acting psychotropic interventional drugs (RAPIDs), including ketamine and psilocybin. This initiative seeks to generate real-world evidence on the effectiveness and safety of these treatments for serious mental illnesses. By addressing critical questions around their implementation in clinical practice, the NIMH aims to facilitate the safe integration of RAPIDs into healthcare, ultimately improving mental health outcomes.
    Mental Health & Psychiatric Diseases Health Care Access & Delivery

    Colleton County Grants for Nonprofits Highlights

    Looking for Colleton County grants for nonprofits?


    Read more about each grant below or start your 14-day free trial to see all Colleton County grants recommended for your specific programs.

    Last updated: November 2, 2026. Next update: December 6, 2026.

    Grant Insights : Grant Funding Trends in South Carolina

    Average Grant Size

    What's the typical amount funded for South Carolina?

    Grants are most commonly $74,506.

    $74,506

    Total Number of Grants

    What's the total number of grants in Colleton County Grants for Nonprofits year over year?

    In 2024, funders in South Carolina awarded a total of 24,410 grants.

    2022 21,855

    2023 21,722

    2024 24,410

    Top Grant Focus Areas

    Among all the Colleton County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

    1. Education

    2. Philanthropy, Voluntarism & Grantmaking Foundations

    3. Human Services

    Funding Over Time

    How is funding for Colleton County Grants for Nonprofits changing over time?

    Funding has increased by 22.06%.

    2022 $1,534,818,247

    2023 $1,485,349,233
    -3.22%

    2024 $1,813,067,383
    22.06%

    South Carolina Counties That Receive the Most Funding

    How does grant funding vary by county?

    Greenville County, Richland County, and Charleston County receive the most funding.

    County Total Grant Funding in 2024
    Greenville County $580,646,902
    Richland County $413,417,941
    Charleston County $355,724,083
    Spartanburg County $325,246,878
    Pickens County $159,596,081