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Best Darlington County Grants for Nonprofits in South Carolina

Looking for grants for 501(c)(3) nonprofit organizations working in Darlington County? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

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$2.61B

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$5K

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9,000+ grants
$2.61B total
$5K median

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9,244 Results based on applied filters

Dollar Tree Gift Card Program

Alpenglow Impact
Private
Arizona, California +12 more
US $2,500 - US $10,000

Every Kindness is a Gift

Dollar Tree Gift Card Program 2026

Every Kindness is a Gift is a gift card grant program made possible through the generosity of Dollar Tree and managed by the team here at Gift Card Bank. We are a nonprofit organization that specializes in the distribution of gift cards and our mission is to improve well-being and build financial stability by supporting people through their time of need.

Through Every Kindness is a Gift, nonprofit organizations and Title I schools located in the 48 contiguous states may apply to receive a grant of Dollar Tree gift cards.

Gift cards received through these grants are meant to be distributed directly to individuals and families in need. A primary goal of the program is to give gift card recipients the dignity of choice by empowering them to shop for what they need themselves. By putting gift cards directly in the hands of our neighbors in need, we are able to increase access to essentials like food, school supplies, paper products, cleaning products, and hygiene items.

In 2026, there will be two rounds of grant distributions. In each round, we will award a number of grants between $2,500 and $10,000.

Round One is a summer distribution. Gift cards awarded in Round One will arrive in late June, while kids are on break and back-to-school is around the corner. Round Two is a holiday distribution. Gift cards awarded in Round Two will arrive in early November, as the end-of-year holidays approach.

We know that these are times of year when budgets are tight. Through these gift card grants, we hope to connect individuals and families directly to the essential resources they need during difficult months.

Basic Human Needs Family Services Disaster Relief / Humanitarian Aid +5 more

Alzheimer’s Resource Coordination Center (ARCC) Grant

South Carolina Department on Aging
State/Local Government
South Carolina
US $20,000 - US $50,000

Alzheimer’s Resource Coordination Center (ARCC)

Overview

The Alzheimer’s Resource Coordination Center (ARCC), located within the South Carolina Department on Aging, was established by state legislation in 1994. The Center’s goal is to serve as a statewide focal point for coordination, service development, information, and education to assist persons with ADRD and their families. The ARCC is guided by a Governor-appointed advisory council composed of representatives from state agencies, organizations, and caregivers who have a special interest in Alzheimer’s disease and related dementias (ADRD). The advisory council aids the ARCC in meeting its goals of:  

  • Initiating the development of systems which coordinate the delivery of programs and services
  • Facilitating the coordination and integration of research, program development, planning, and quality assurance
  • Identifying potential users of services and gaps in the service delivery system and expanding methods and resources to enhance statewide services
  • Serving as a resource for education, research, and training and providing information and referral services
  • Providing technical assistance for the development of support groups and other local initiatives to serve individuals, families, and caregivers
  • Recommending public policy concerning Alzheimer's disease and related disorders to state policymakers
  • Facilitating the coordination and integration of educational initiatives for healthcare providers on the importance and value of early detection and timely diagnosis of cognitive impairment, validated cognitive assessment tools, and increasing understanding and awareness of early warning signs of Alzheimer’s disease and other types of dementia and how to reduce the risk of cognitive decline.

The ARCC is staffed by the Dementia Coordinator whose role is to monitor the state’s service delivery system and work closely with the ARCC Advisory Council to develop a coordinated state-wide delivery system that caters to the needs of persons with ADRD, their families, caregivers, and communities. Additionally, the Dementia Coordinator is responsible for submitting an annual report to the Chairman of the Medical Affairs Committee of the Senate and the Chairman of the Medical, Military, Public, and Municipal Affairs Committee of the House of Representatives on the activities of the ARCC.

ARCC Grants

Each year, the ARCC receives $150,000 to award dementia-specific grants to community organizations to support respite, education, and innovative programs for individuals living with Alzheimer’s and related dementias, their families, caregivers, and communities. Grants are awarded on a 2-year cycle through a competitive selection process. 

Since its establishment in 1995, the ARCC Grants Program has awarded over 388 grants to community organizations that provide services to individuals, families, and communities affected by dementia. These services include dementia-specific respite, adult day programs, and educational programs that support the medical community, colleges and universities, first responders, and the general public. The ARCC grants have enabled more than 7,717 individuals living with ADRD to access respite care services and provided education services to over 78,117 participants. Moreover, since 2021, ARCC grants have supported the implementation of 17 innovative programs. These programs include virtual training for family caregivers, in-home activities that promote sustainability and independence in daily living for those with dementia, and technology that helps locate and safely return those with dementia who may have wandered from home.

During the FY25 grant period (July 1, 2024 to June 30, 2025), a total of 10 ARCC grants were awarded, providing services across 14 counties. 

Dementia & Alzheimer’s Disease Caregiver Support / Respite Care

Rural Health Transformation Program: Wellness Within Reach Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $50,000 - US $2,000,000

The Wellness Within Reach initiative aims to bring high-quality, face-to-face healthcare directly to rural South Carolina communities through mobile units, crisis response teams, and community-based care sites This grant opportunity seeks proposals from eligible organizations to strengthen South Carolina’s mobile crisis response and expand community care sites.

Mental Health & Psychiatric Diseases Crisis Intervention Community Health Education +1 more

Rural Health Transformation Program: Shoring Up to Sustainability Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $500,000 - US $3,000,000

The Rural Health Transformation Program (RHTP), established under the Working Families Tax Cuts Act signed into law on July 4, 2025, is a federal initiative led by the Centers for Medicare & Medicaid Services (CMS). This program is designed to help state governments strengthen healthcare access, quality, and outcomes in rural communities by transforming the healthcare delivery ecosystem. Through a focus on innovation, strategic partnerships, infrastructure development, and workforce investment, the RHTP aims to create sustainable improvements in rural health systems across the United States. The Shoring Up to Sustainability initiative aims to strengthen the operational and financial resilience of rural healthcare systems in South Carolina by investing in critical facility enhancements and delivering targeted masterclass training for rural providers.

Rural Health Care

Mark Mayden Scholarship

The Community Foundation of Dickinson County Inc.
Private
United States
US $700
The Mark Mayden Scholarship, established in 2006 by the Community Foundation of Dickinson County, honors the legacy of Mark Mayden, a devoted supporter of agribusiness. This $700 scholarship aims to assist hardworking students from Dickinson County in pursuing technical or vocational education, fostering opportunities for future generations. By rewarding initiative and talent, the scholarship reflects Mark's belief in the transformative power of education and hard work, ensuring that deserving students have the support they need to succeed.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

Loren Engel Memorial FFA Scholarship

The Community Foundation of Dickinson County Inc.
Private
United States
US $300
The Loren Engel Memorial FFA Scholarship, established by Margaret Engle in 2005, honors Loren Engel’s dedication to agriculture and leadership. This $300 scholarship is available for graduating high school students from Dickinson County who have served as FFA chapter officers, demonstrating commitment to agricultural education. The Community Foundation of Dickinson County aims to support local students pursuing technical or vocational education, ensuring future generations can thrive in their community.
Education - Higher Education Vocational & Trade Education Education - High School +1 more

The Vanguard Award

Remuseum Inc.
Private
United States
US $100,000

The Vanguard

Remuseum announces The Vanguard, an award and accelerator for innovative leaders in the visual and performing arts, in partnership with the Doris Duke Foundation. The Vanguard’s $100,000 annual award will recognize up to ten leaders who are exploring new ways to strengthen arts institutions, and a year-long accelerator will help them refine, implement, and evaluate their ideas. The first award and accelerator of its kind, The Vanguard celebrates leaders who are ready to center the public in their work in new ways, building models for increased relevance and sustainability in the arts.

The Program

The $100,000 grant that accompanies each award will go to that leader’s institution, to support ideas developed in The Vanguard’s 12-month accelerator program. That program begins with a week-long retreat at Shangri La, the Doris Duke Foundation’s global center for culture and ideas in Honolulu, Hawaii, followed by a year of monthly coaching sessions, regional peer gatherings, and collaborative workshops, culminating in a public presentation of their work and findings to the broader arts community. The accelerator and its curriculum, tailored specifically for cultural leaders, has been designed by Jenny Larios Berlin, entrepreneur in the creative and tech sectors and Lecturer at MIT Sloan School of Management, and will be co-taught with Gregory Bunch, entrepreneur and Adjunct Professor of Entrepreneurship at the University of Chicago Booth School of Business, and will be advised by Ethernet Inventors Professor of Entrepreneurship Bill Aulet, Managing Director of the Martin Trust Center for MIT Entrepreneurship.

By year’s end, members of The Vanguard will have built an intellectual kinship with each other while modeling a spirit of innovative leadership for the field. Remuseum will continue evaluating and sharing their work as case studies for cultural organizations broadly, and future classes will continue expanding a Vanguard of leaders (10, then 20, and on) who build models of success for cultural organizations in the 21st Century, allowing arts & cultural institutions not just to survive but to support a stronger and more pluralistic civil society.

Art & Culture Nonprofit Growth & Development Arts / Culture Access & Participation

SC Housing Trust Fund (HTF) — Critical Home Repair Program Grant

South Carolina State Housing Finance and Development Authority
State/Local Government
South Carolina
US $5,000 - US $30,000

South Carolina Housing Trust Fund (HTF)

The South Carolina Housing Trust Fund (SC HTF) is a valuable resource for developing and maintaining safe, quality affordable housing for low to very low-income households within the state. Funding and assistance for eligible home repairs and supportive housing projects are provided through three core programs—The Home Repair Program, Critical Home Repair Program, and Supportive Housing Program. SC Housing administers the HTF program in partnership with other government organizations, non-profit sponsors and affordable housing developers. The HTF program also coordinates its efforts with other federal, state, and local housing assistance programs to achieve maximum benefit for participants.

The Critical Home Repair Program provide financial assistance to help low to very low-income homeowners with essential interior and exterior home repairs to correct life, health and safety issues so that they can live safely in their homes. These programs help to repair or replace major housing systems, including roofs, water heaters and HVAC equipment. It also covers home modifications, such as ramps, to provide accessibility for persons who are disabled. A home inspection is conducted to help identify any additional repairs that may be needed to provide the homeowner with safe and decent living conditions. The Sponsor then coordinates completion of the work with qualified contractors. The homeowner benefits by staying safely in a home that they can continue to enjoy for years to come. Local communities also benefit by maintaining the supply of affordable homes in their area.

Homeownership Equitable & Affordable Housing Energy Efficiency & Conservation

Rural Health Transformation Program: Leveling Up Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $100,000 - US $5,000,000

The Leveling Up initiative aims to expand and integrate proven chronic disease management programs statewide, ensuring rural communities have access to comprehensive, coordinated care for serious and chronic conditions such as diabetes, hypertension, and sickle cell disease. Historically, these programs have been implemented in limited regions due to resource constraints, leaving rural areas underserved and often last to benefit from advancements in chronic care. This grant opportunity seeks proposals from eligible organizations to expand chronic disease programs.

Chronic Illnesses Rural Health Care

Rural Health Transformation Program: Connections to Care Initiative

South Carolina Department of Health and Human Services
State/Local Government
South Carolina
US $100,000 - US $10,000,000

The Connections to Care initiative aims to modernize and expand digital infrastructure across South Carolina’s rural healthcare ecosystem. This grant opportunity seeks proposals from eligible organizations to implement or enhance electronic health records (EHRs) and remote patient monitoring (RPM).

Health Information Technology Rural Health Care

Washington County Hospital School of Nursing Alumni Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County Hospital School of Nursing Alumni Scholarship

Founded by alumni of Washington County Hospital’s School of Nursing, this fund serves to provide scholarships to deserving students who are continuing their education in Nursing.

Education - Higher Education Nursing

Washington County Arts Council, Inc. Foundation Scholarship Fund

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County Arts Council, Inc. Foundation Scholarship Fund

The Washington County Arts Council, Inc. welcomes all applicants interested in pursuing a 2- or 4-year degree, or a certificate program, from an accredited educational institution with an emphasis on the arts. All students, including those individuals who have pursued a non-traditional education path, will be considered for this scholarship.

Education - Higher Education Art Education

Washington County 4-H Livestock/Market Sale Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Livestock/Market Sale Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H Livestock and Market Sale programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

Washington County 4-H Dairy Scholarship

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

Washington County 4-H Dairy Scholarship

Established to support post-secondary scholarships to participants in Washington County 4-H dairy programs.

Education - Higher Education Livestock & Ranching Agricultural Economics +1 more

The Tim Moffatt Career Advancement Award

Community Foundation of Washington County Maryland
Private
United States
Unspecified amount

This Community Foundation was created by and for the people of Washington County MD, and exists to improve the quality of life for all of our citizens, now and for generations to come, by building community endowments, addressing needs through grant making and providing leadership on key community issues.

The Tim Moffatt Career Advancement Award

This scholarship will be awarded to deserving students who are graduating from a WCPS high school, or are a non-traditional learner with equivalent education, who have been accepted into a trade school/program/apprenticeship, or who have enlisted in the military. 

Education - Higher Education Vocational & Trade Education

Pi-Squared Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Pi-Squared Scholarship

Benefiting graduating seniors of Spring ISD (Texas), Klein ISD (Texas), and Houston ISD (Texas).

Education - Higher Education Career / College Preparation

Roger and Barbara Powell Scholarship for Nursing

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Roger and Barbara Powell Scholarship for Nursing

Benefiting rural Texas residents pursuing nursing degrees.

Education - Higher Education Nursing

Silver Eagle Distributors Houston Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Silver Eagle Distributors Houston Scholarship

Benefiting dependents of Silver Eagle Distributors Houston employees.

Education - Higher Education Career / College Preparation

Tradition of Excellence Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Tradition of Excellence Scholarship

Benefiting dependents of current Perry Homes employees.

Education - Higher Education Career / College Preparation

Strong Family Scholarship

Greater Houston Community Foundation
Private
United States
Unspecified amount

The Greater Houston Community Foundation (GHCF) administers a variety of unique scholarship funds that grant over $5.7 million annually to college students. The scholarship funds have been established by thoughtful and generous donors and each has a unique set of eligibility criteria and award structure.

Strong Family Scholarship

Benefiting graduating high school seniors from charter schools in Houston, TX.

Education - Higher Education Career / College Preparation

Taka Domingo HLP Vocational Scholarship

HLP Hamakua Community Foundation
Association/Society
United States
US $2,000

Taka Domingo HLP Vocational Scholarship

The HLP Hamakua Community Foundation is a non-profit organization that was formed to benefit the people of Hamakua. Taka Domingo was one of the original board members when HLP was established after the closure of sugar. He was an electrician and County Councilman representing the Hamakua District. The Taka Domingo HLP Vocational Scholarship was established after his death in August 2016. 

Individual award amount: $2,000. 

Possible trades include: welding, tourism, fire science, electrical, early childhood education, agriculture, auto body, auto mechanics, diesel mechanics, carpentry, culinary and others not listed.

Vocational & Trade Education

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

Pfizer, Inc.
Corporate
Brazil, China +7 more
Up to US $50,000

Pfizer supports the global healthcare community’s independent initiatives (e.g., research, quality improvement or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies.

Pre-clinical Investigation of anti-TFPI-mediated Rebalancing Mechanisms in Non-Hemophilic Bleeding Disorders

There remains a scientific gap in understanding of the role of anti-TFPImediated hemostatic rebalancing in the context of inherited or non-hemophilic bleeding disorders. This competitive grant program encourages competitive submissions focsed on generating preclinical/foundational data exploring the therapeutic potential and mechanisms of TFPI modulation in bleeding disorders other than hemophilia.

Funding

  • Individual projects requesting up to $50,000 USD will be considered. Request for study drug or compound is allowed (max $50,000 USD), additionally to the study project costs.
  • Maximum project length is 1 year.
Rare Diseases Hematological Systems

St. Ignace Area Community Foundation: CTE Technical Scholarship

St. Ignace Area Community Foundation
Association/Society
United States
Unspecified amount

St. Ignace Area Community Foundation: CTE Technical Scholarship

The St. Ignace Community Fund annually awards scholarships assisting students with higher education, technical training, vocational training or retraining based largely on acknowledgement of student responsibility, community service, and civic involvement. These Scholarships are made possible through the generosity of donors to the various accounts within the St. Ignace Area Community Fund. Some accounts specifically are awarded to recognize higher education in the areas of special education, vocational/technical careers, teaching, law enforcement, and health care.

Vocational & Trade Education Nursing Special Needs Education +2 more

Susan G. Komen Career Catalyst Research Grant

The Susan G Komen Breast Cancer Foundation Inc
Private
United States
Up to US $150,000

Susan G Komen Breast Cancer Foundation

The mission of Susan G. Komen® is to save lives by meeting the most critical needs in our communities and investing in breakthrough research to prevent and cure breast cancer.

Susan G. Komen Career Catalyst Research (CCR) Grants

Susan G. Komen Career Catalyst Research (CCR) Grants foster promising breast cancer researchers who are in the early stages of their faculty careers by providing support for up to three years of “protected time” for research career development under the guidance of a Mentor Committee. We seek to support those who will emerge as the next key leaders in the fight against breast cancer.

CCR Research Focus: Research projects must be hypothesis-driven, breast cancer-focused studies. They may be considered basic, translational, clinical and/or population science in nature and should align with Komen’s research priorities and mission to save lives from breast cancer. 

Breast Cancer

Readiness and Recreation Initiative (RARI) – Recurring 5 Year Notice

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $3,000,000
The Readiness and Recreation Initiative (RARI) by the National Park Service aims to enhance outdoor recreation and support compatible land uses near military installations. This program, funded through the Land and Water Conservation Fund, provides up to 50% of project costs, encouraging collaboration with the Department of War. Projects must involve land acquisition and align with national priorities to ensure public outdoor access in perpetuity, directly benefiting both military and civilian communities.
Urban Planning Outdoor Recreation Disaster Preparedness +1 more

Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026

US HUD: Office of Public and Indian Housing (PIH)
Federal Government
United States
US $500,000 - US $7,500,000
The Indian Housing Block Grant Competitive Program (IHBG-COMP) for FY 2026 offers competitive grants to eligible recipients under NAHASDA. This program aims to support affordable housing initiatives benefiting low-income Tribal families, enhancing their living conditions and community well-being. Funded by the US HUD's Office of Public and Indian Housing, the IHBG-COMP encourages the development of sustainable housing solutions within Native American communities.
Minority Services Equitable & Affordable Housing Native American Services

Stephany June Bryan: Bold Spirit of Achievement Scholarship

Hogg Foundation for Mental Health
State/Local Government
United States
US $5,000

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Stephany June Bryan: Bold Spirit of Achievement Scholarship

The Hogg Foundation for Mental Health is offering ten $5,000 scholarships in honor of Stephany June Bryan to individuals facing personal and financial barriers to achieving their educational or career goals due to the impact of living with a mental health challenge and/or supporting a loved one with a mental health challenge.

You do not need to be enrolled in a program at the time you submit your application. However, you will need to provide enrollment verification and/or a certificate of completion when/if it is awarded.

Mental Health & Psychiatric Diseases Education - Higher Education Vocational & Trade Education +2 more

Darlington County Grants for Nonprofits Highlights

Looking for Darlington County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Darlington County grants recommended for your specific programs.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Darlington County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Darlington County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Darlington County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081