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Best Fairfield County Grants for Nonprofits in South Carolina

Looking for grants for 501(c)(3) nonprofit organizations working in Fairfield County, South Carolina? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.61B

Total funding

$5K

Median grant

9,000+ grants
$2.61B total
$5K median

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9,222 Results based on applied filters

NIJ FY 2026 Research on Gender Dysphoria and Violent Crime

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIJ FY 2026 Research on Gender Dysphoria and Violent Crime funding opportunity aims to support crucial research exploring the connections between gender dysphoria and violent behavior. This initiative seeks to fill gaps in empirical evidence, focusing on aspects such as prevalence rates of violent crime, post-conviction analyses, and the impact of comorbidities on violence. Researchers are encouraged to conduct retrospective data analyses to better understand these complex relationships and inform future treatment and intervention strategies.
Mental Health & Psychiatric Diseases Crime & Justice Violence Prevention +1 more

OJJDP FY 2026 Opioid Affected Youth Initiative

US DOJ: Office of Justice Programs
Federal Government
American Samoa, Guam +4 more
Up to US $750,000
The OJJDP FY 2026 Opioid Affected Youth Initiative provides funding to support states and localities in combating violent crime and overdose deaths. This initiative aims to enhance prevention, intervention, and treatment strategies for children, youth, and families impacted by substance use disorders. Collaboration among law enforcement, educational institutions, and community organizations is essential to effectively address the needs of at-risk populations and those already involved in the child welfare and justice systems.
Youth Services Family Services Crime & Justice +1 more

OJJDP FY 2026 Strategies to Support Children Exposed to Violence

US DOJ: Office of Juvenile Justice & Delinquency Prevention (OJJDP)
Federal Government
American Samoa, Guam +4 more
Up to US $815,000
The OJJDP FY 2026 Strategies to Support Children Exposed to Violence program aims to implement effective violence reduction strategies targeting juvenile offenders. This initiative focuses on enhancing community capabilities to assist children affected by violence in various environments, including homes and schools. By strengthening local responses to child victimization, the program seeks to diminish the incidence of violence and alleviate the long-term adverse effects that such exposure can have on children's well-being.
Mental Health & Psychiatric Diseases Youth Services Crime & Justice +2 more

SMART FY26 Support for Adam Walsh Act Implementation Grant Program

US Department of Justice: Office of Sex Offender Sentencing, Monitoring, Apprehending, Registering, and Tracking (SMART)
Federal Government
American Samoa, Guam +4 more
Up to US $400,000
The SMART FY26 Support for Adam Walsh Act Implementation Grant Program aims to enhance sex offender registration and notification practices across jurisdictions in the U.S. By supporting the implementation of the Sex Offender Registration and Notification Act (SORNA), this grant facilitates the establishment of comprehensive sex offender registries, ensuring that states, territories, and federally recognized tribes comply with federal standards. This initiative also promotes interjurisdictional information exchange and helps maintain public safety.
Public Policy Community / Public Safety Emerging Technology Development

NIJ FY 2026 Research and Evaluation on Human Trafficking

US Department of Justice: National Institute of Justice (NIJ)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The NIJ FY 2026 Research and Evaluation on Human Trafficking funding opportunity aims to support comprehensive research and evaluation projects. It focuses on preventing human trafficking, assessing the impact of federal policies, and enhancing services for victims. This initiative, led by the National Institute of Justice in partnership with the Office for Victims of Crime, seeks to generate insights that can inform better responses to human trafficking in the U.S.
Public Policy Human Trafficking Crime Victim Services

Small Business Innovation Research (SBIR) program, Phase I (363966)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $95,000 - US $100,000
The Small Business Innovation Research (SBIR) program, Phase I, aims to stimulate technological innovation in the private sector, enhancing the role of small businesses in meeting Federal research needs. Specifically, ACL's SBIR program focuses on improving the lives of individuals with disabilities through research and development products. The initiative includes 11 grants with a 6-month project period to assess the feasibility of innovative concepts, contributing to economic and social benefits.
Disability Care & Services Emerging Technology Development Business Development

Advanced Rehabilitation Research Training (ARRT) Program - Community Living and Participation (363963)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the skills of researchers in the field of disability and rehabilitation. By providing advanced training over a three-year period, this program focuses on improving community living and participation outcomes for individuals with disabilities. It seeks to equip scholars with the necessary tools to conduct high-quality, multidisciplinary research, ultimately benefiting the disability community.
Disability Care & Services Medical Rehabilitation Medical Education & Professional Training

Alzheimer's Disease Programs Initiative (ADPI) - Developing Dementia-Capable Community Health Worker Programs in the National Aging Network

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $200,000 - US $250,000
The Alzheimer's Disease Programs Initiative (ADPI) aims to foster the development of dementia-capable community health worker programs within the National Aging Network. This initiative, supported by the US HHS: Administration for Community Living (ACL), seeks to enhance dementia screening, reduce barriers to care, and improve access to essential services for individuals with dementia and their caregivers. By integrating community health workers into aging services, the program aspires to elevate the quality of life for those affected.
Aging / Gerontology Mental Health & Psychiatric Diseases Health Care Access & Delivery +2 more

Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $970,000 - US $975,000
The Rehabilitation Engineering Research Center on Recreational, Sport, and Exercise Technologies for People with Disabilities aims to enhance rehabilitation services through innovative technological solutions. This initiative focuses on promoting health and exercise among individuals with disabilities by addressing unique rehabilitation challenges. Funded by the US HHS Administration for Community Living, the project spans 60 months, involving advanced research and development to create effective support mechanisms and overcome environmental barriers.
Engineering Disability Care & Services Medical Rehabilitation +1 more

Field Initiated Projects Program (Research) (363972)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Field Initiated Projects Program aims to foster new research and develop solutions that enhance the inclusion and independence of individuals with disabilities. This initiative focuses on generating scientific knowledge and understanding critical issues faced by these populations, particularly those with significant support needs. With a total of 16 grants available over a 36-month period, this program encourages innovative approaches that support employment, living arrangements, and caregiver involvement.
Disability Care & Services Medical Rehabilitation Employment Services

Rehabilitation Research and Training Center (RRTC): National Research Center for Parents with Disabilities (363975)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $920,000 - US $925,000
The Rehabilitation Research and Training Center (RRTC) focuses on enhancing the lives of parents with disabilities through research, training, and technical assistance. This initiative aims to develop evidence-based services and supports that empower parents in their caregiving roles. Funded by the US HHS: Administration for Community Living (ACL), the project spans 60 months with a commitment to fostering inclusive environments for families. The RRTC will explore innovative interventions and technologies to better support these parents in their daily challenges.
Disability Care & Services Family Services

Rehabilitation Engineering Research Center on Technologies for People Who are Blind or have Low Vision

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $970,000 - US $975,000
The Rehabilitation Engineering Research Center aims to enhance services for individuals who are blind or have low vision through innovative technology development. This initiative focuses on overcoming rehabilitation challenges and environmental barriers, promoting independence and community living. A grant of five years will support ongoing research efforts, ensuring advancements in assistive technologies that empower the target population. The project aligns with the Rehabilitation Act's goals, emphasizing the importance of accessibility and inclusion.
Disability Care & Services Medical Rehabilitation Emerging Technology Development

Center on Knowledge Translation for Disability and Rehabilitation Research

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $795,000 - US $800,000
The Center on Knowledge Translation for Disability and Rehabilitation Research (KTDRR Center) aims to enhance the use of relevant disability and rehabilitation research through effective knowledge translation. Serving as a key resource for NIDILRR grantees and the general public, the KTDRR Center's initiatives will support high-quality research dissemination. The project spans 60 months, including five 12-month budget periods, ensuring ongoing support for researchers and stakeholders in the field.
Disability Care & Services Medical Rehabilitation

Burn Injury Model System Centers

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $560,000 - US $640,000
The Burn Injury Model System Centers aim to enhance burn rehabilitation through innovative research. These centers must create knowledge to improve the health, community engagement, and employment outcomes for individuals affected by burn injuries. Funded by US HHS's Administration for Community Living, grants support site-specific and collaborative research while contributing to a longitudinal database. Each grant has a maximum duration of 60 months, divided into five budget periods, ensuring comprehensive support for ongoing studies.
Disability Care & Services Medical Rehabilitation

Field Initiated Projects Program (Development) (363971)

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $245,000 - US $250,000
The Field Initiated Projects Program (Development) aims to enhance the inclusion and self-sufficiency of individuals with disabilities through innovative research and development. This program supports the creation of tools, methods, and systems that assist people with disabilities, particularly those with significant support needs. With 16 grants available, the initiative will span 36 months, focusing on impactful projects that foster independence, employment, and community integration.
Disability Care & Services Medical Rehabilitation Emerging Technology Development

Traumatic Brain Injury Model Systems Centers

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $560,000 - US $640,000
The Traumatic Brain Injury Model Systems Centers aim to enhance TBI rehabilitation through evidence-based research. These centers focus on generating knowledge to improve health, community participation, and employment outcomes for TBI individuals. Funded by the US HHS Administration for Community Living, the grants support site-specific and collaborative research, contributing to a longitudinal database. Each center can receive varying funding amounts, depending on eligible database participants, with a project timeline of 60 months comprising five 12-month budget periods.
Disability Care & Services Neurological Diseases & Disorders Medical Rehabilitation

Lifespan Respite Care Program: State Grants

US HHS: Administration for Community Living (ACL)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $500,000
The Lifespan Respite Care Program invites state agencies to apply for grants aimed at enhancing respite services for caregivers of individuals with disabilities or chronic conditions. This initiative supports both new states and those re-establishing their programs, focusing on collaboration, training, and outreach to address the respite needs of diverse populations. Approximately ten cooperative agreements will be funded over three years, aligning with federal requirements for lifespan respite care.
Community Services Disability Care & Services Family Services

National Breastfeeding Support, Implementation, and Hospital Quality Improvement Initiative

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Breastfeeding Support Initiative aims to enhance maternity care quality by engaging diverse partners and providing training to healthcare organizations. It focuses on implementing evidence-based practices to support breastfeeding, ensuring safe and effective maternity care in hospitals across the U.S. and territories. By fostering collaboration and utilizing data for quality improvement, the initiative seeks to create a sustainable impact on maternal and infant health.
Women's Health Maternal And Perinatal Health Health Care Access & Delivery

Launchpad Funds: Seed and Scaling Funding

Coefficient Giving
Private
Countries
US $10,000,000 - US $50,000,000

Request for Proposals: Launchpad Funds

Background

Coefficient Giving is increasing its giving, primarily to prepare for the billions of dollars in new philanthropic capital that may become available in the coming years. Our increased giving in global health and wellbeing is a temporary surge, with two objectives: to smooth funding and pull forward initiatives we expect to be cost-effective, and to help create an ecosystem of regrantors and implementers with the capacity to allocate this new money as cost-effectively as possible. Additional context on our scaling is provided in this blog post. 

With new potential capital on the way, we want to increase the supply of actionable and fundable plans to address some of the world’s hardest problems. We’re looking for specific, credible strategies to convert funding into measurable progress. Our ideal funds are:

However, we are also open to funds that are thematic and don’t have a quantified goal — for example, a fund organized around a promising type of intervention. Such funds still need to be led by a single, identifiable person who is accountable for the fund’s direction.

Through this request for EOIs, we aim to seed or scale Launchpad Funds that can grow to $100m+ over the next few years. We don’t seek scale for its own sake; it is a proxy for the ambition of the fund, and a signal that the problem is large and tractable enough to justify deploying significantly more capital over time.

What we will fund

  • We expect to support established ideas that have either not yet secured anchor support or could significantly scale beyond their existing level of funding.
  • This funding can cover operating expenses, but we expect most of it to be used for activities that make progress on the fund’s goals — whether through regranting or direct implementation.
  • For exceptional proposals, we may consider funding levels beyond $50m. We anticipate higher funding levels will involve more thought partnership from our team.
  • While we don’t expect to make grants longer than 36 months, funded proposals may later be considered for additional funding beyond the initial period.

Urban Planning Public Policy Food Access & Hunger +13 more

NASA Innovative Advanced Concepts (NIAC) Phase I (363983)

National Aeronautics and Space Administration (NASA)
Federal Government
American Samoa, Guam +4 more
Up to US $225,000
The NASA Innovative Advanced Concepts (NIAC) Phase I program invites proposals for groundbreaking aerospace concepts, aiming to transform potential in aeronautics. This initiative supports innovative research through multiple award phases, focusing on Phase I requirements and evaluation criteria. A virtual forum will be held on October 7, 2026, to discuss the Appendix’s details and clarify submission guidelines. Additional information will be available on the NSPIRES page, ensuring participants are well-informed about the process.
Aerospace Engineering Space Science Emerging Technology Development

National Parks Business Plan Internship

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,700,000
The National Parks Business Plan Internship aims to enhance the operational health of national parks through a graduate-level program that trains students in business management and NPS operations. Participants will engage in substantive analysis, gain insights into park management, and promote federal careers in conservation. This initiative seeks to involve underrepresented graduate students from disciplines such as business administration and public policy, fostering a commitment to stewardship of public lands.
Education - Higher Education Environmental Education Workforce Preparation & Job Readiness +1 more

Promoting Cancer Surveillance Workforce, Education, and Data Use (363986)

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Unspecified amount
This funding opportunity aims to enhance the cancer surveillance workforce through education and support for certified Oncology Data Specialists. The initiative will improve the quality and completeness of cancer data collected by the National Program of Cancer Registries. By fostering collaboration and promoting the value of cancer surveillance data, this program seeks to empower public health actions, research, and policy-making, ensuring a robust response to current and future cancer-related challenges.
Cancer / Oncology Epidemiology & Public Health Medical Education & Professional Training

Highway Safety Grants

South Carolina Department of Public Safety
State/Local Government
South Carolina
Unspecified amount

The South Carolina Department of Public Safety's Office of Highway Safety and Justice Programs (OHSJP) is charged with the responsibility of the administration of the federally-funded State and Community Highway Safety (Section 402) Program and coordination of highway safety activities throughout the state on behalf of the Office of the Governor.  Highway Safety grant funds are awarded to qualified applicants to create new or expand existing highway safety programs, with the intention that such initiatives continue when grant funding is discontinued.  Applications must address at least one of the following priority emphasis areas, and/or support strategies found in South Carolina’s Strategic Highway Safety Plan (SHSP), or other traffic safety program areas that are identified and supported by data. 

  • Police Traffic Services
  • Impaired Driving Countermeasures
  • Highway Safety Education
Automotive Safety Police & Law Enforcement

Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $750,000
The Collaborative Centers in Children’s Environmental Health Research and Translation program aims to establish a national network of research centers focused on improving children's health through innovative research and public health strategies. By fostering collaboration within the children’s environmental health community, these centers will lead the way in translating scientific findings into actionable practices, ensuring a healthier future for children while addressing emerging environmental threats.
Epidemiology & Public Health Environmental Health Children’s Health & Pediatrics

Immune Drivers of Autoimmune Disease

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Immune Drivers of Autoimmune Disease (IDAD) network, supported by NIAID, aims to uncover early triggers and mechanisms of autoimmunity to prevent disease. Key initiatives include developing predictive tools and biomarkers, fostering preclinical cohorts, and utilizing AI and big data. The network will leverage shared infrastructure for collaborative research, managed by the IDAD Network Coordinating Center, which ensures coordination and resource sharing among awardees. This initiative is crucial for advancing understanding and prevention of autoimmune diseases.
Immune System Diseases Preventative Healthcare Emerging Technology Development

NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) (363939)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $80,000
The NLM Grants for Scholarly Works in Biomedicine and Health (G13) program invites applications to support the creation of book-length manuscripts and scholarly works that are vital for U.S. health professionals and scientists. This initiative aims to foster critical reviews and analytical syntheses that enhance understanding of biomedical and public health challenges, ultimately contributing valuable resources for education, research, and clinical practice.
Health & Medicine Epidemiology & Public Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

Fairfield County Grants for Nonprofits Highlights

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Read more about each grant below or start your 14-day free trial to see all Fairfield County grants recommended for your specific programs in South Carolina.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Fairfield County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Fairfield County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Fairfield County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081