Best Fairfield County Grants for Nonprofits in South Carolina

The National Institute on Aging (NIA) is announcing a funding opportunity to support the Exceptional Longevity Data Management and Coordinating Center (EL DMCC). This initiative aims to enhance the management of large, diverse datasets and facilitate collaborative research across NIA projects. Core functions include data integration, AI/ML infrastructure development, and maintaining the ELITE Portal for secure data access. This NOFO encourages innovative approaches to longevity research, though applications are not currently being solicited.

The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance the development of diagnostic tests for infectious diseases through strategic partnerships between academia and industry. By fostering collaborations, NIAID seeks to overcome barriers to commercialization, ensuring promising diagnostics reach the market effectively. This initiative aligns with NIH's mission to advance innovative technologies that improve treatment and prevention strategies for infectious diseases, ultimately contributing to public health advancements.

About

Originally conceived by Dr Bruce Mesara in 1990 as a means to carry on his philanthropic efforts beyond his lifetime, the Mesara Family Foundation was re-envisioned by his two children Amy and Douglas in 2014, and received their 501(c)(3) status from the IRS in 2015. Amy and Douglas sought out the assistance of their cousins to build upon the charitable principals on their parents, aunts and uncles.

The foundation is headquartered in Kalamazoo Michigan.

Mission

The mission of the Mesara Family Foundation is to honor the philanthropic principles of the Mesara and Pauch families by supporting carefully selected organizations that share similar values. Our focus is to provide support toward education, conservation and other causes of special family interest where our funding will make a genuine difference.

About SCRA

The South Carolina Research Authority (SCRA) was chartered in 1983 by the State of South Carolina as a public, non-profit organization. The mission of SCRA is to fuel South Carolina’s Innovation Economy by accelerating technology-enabled growth in research, academia, entrepreneurship, and industry. SCRA supports its stakeholders in key technology sectors, which include but are not limited to, Advanced Materials/Manufacturing; Life Sciences; Clean Tech, Sustainability, and Resilience, and Information Technology. SCRA grant funding is made possible, in part, by Industry Partnership Fund (IPF) contributions. Contributors receive a dollar-for-dollar South Carolina income tax credit, making it a no-cost way to create a direct, positive economic effect and job creation

Mission

Fuel South Carolina’s innovation economy by accelerating technology-enabled growth of academia, entrepreneurship, and industry.

Vision

SCRA will be a leading catalyst in making South Carolina the top choice for technology-focused industry, entrepreneurs, investors, and academics.

Federal Matching Grant (formerly SBIR/STTR Phase I)

Managed by the Academic Innovations Team, the objective of the Federal Matching Grant is further federal funds received by small businesses in South Carolina to advance translational research in support of one or more critical milestones towards commercialization. Other Federal matches will be considered on a case-by-case basis. Key milestones include developing the technology past the minimum viable product (MVP) and demonstrating product-market fit, in the DEVELOP stage of startup development. In the ACCELERATE stage of startup development, key milestones include enabling product execution through testing and demonstrations.

2027-2028 Community Mental Health Services Block Grant

The BHDD federal fiscal year 2027-2028 Community Mental Health Services Block Grant Application was available for review and public comment from August 24-31, 2026.

Please note that this application serves as the Agency’s Community Mental Health Services Block Grant State Plan, required by Public Law 102-321, for providing comprehensive community mental health services to adults with a serious mental illness (SMI) and to children with a serious emotional disturbance (SED). The Block Grant is a noncompetitive formula grant that is provided to BHDD Office of Mental Health by the Substance Abuse and Mental Health Services Administration (SAMHSA).

Community Mental Health Services Block Grant (MHBG)

Each year, BHDD receives a two-year grant from SAMHSA. This grant is called the Community Mental Health Services Block Grant (MHBG). It is a noncompetitive grant based on a formula; funding is provided by SAMHSA to 59 recipients. The funding must be used to provide “comprehensive, community-based mental health services” to two types of people: adults with serious mental illnesses (SMI) and children with serious emotional disturbances (SED). Additionally, the funding can be used to help people who are having mental health crises, even if they have not been diagnosed with SMI or SED. Learn more about the block grant here.

There are many different services and programs that can be funded by the block grant – as long as the services fall into the category of “comprehensive, community-based mental health services” for the two types of people listed above, or the services are for people in crisis. This includes services like individual counseling, family counseling, group counseling, psychiatric services, medication management, transitional services, care coordination and crisis interventions.

BHDD provides block grant funding to each of its 16 community mental health centers (CMHCs) and several central administration programs. These CMHCs and programs provide a wide variety of services to patients and people in crisis.

BHDD also allocates block grant funding to nonprofit organizations through a competitive solicitation process. The next available solicitation will fund nonprofits from July 2026 – June 2029. Nonprofit organizations that are interested in applying for block grant funding should check this webpage in the summer of 2025 for more information about the next solicitation.

A Mental Health Planning Council is a required activity for this grant. The purpose of the Planning Council is to ensure collaboration among various state agencies and provide opportunities for people with lived experiences with mental illness to give feedback and input to BHDD. Specific state agencies are required to participate on the council. A minimum of 51% of the Planning Council members must be people with lived experiences with mental illness or family members of people with mental illnesses. 

The BJA FY 2026 John R. Justice Formula Grant Program offers loan repayment assistance to local and state prosecutors and public defenders who commit to three years of service. Administered by state agencies, this program aims to alleviate the financial burden on legal professionals dedicated to public service. Applications are due by November 10, 2026, providing a crucial opportunity for eligible beneficiaries to secure support for their educational loans.

The National Oceanic and Atmospheric Administration (NOAA) is inviting proposals for projects that enhance coastal flood protection through public-private partnerships, innovative insurance products, and improved sediment management. This initiative aims to utilize natural infrastructure to bolster flood preparedness and resilience. Funding of up to $2,000,000 is available for selected projects, supporting research teams that collaborate with regional stakeholders. Proposals must be submitted via Grants.gov, ensuring accessibility to critical resources and information.

The BJA FY 2026 Tribal Justice Training and Technical Assistance Program aims to enhance Tribal justice systems through specialized technical support. This funding opportunity addresses critical issues such as violent crime and substance-use related crime, including opioids. By assisting federally recognized Indian Tribes, the program promotes the development of sustainable legal and corrections infrastructure while fostering collaboration with federal, state, and local partners. Applications are due by October 28, 2026, at 8:59 p.m. ET.

The OJJDP FY 2026 Second Chance Act Youth Reentry Program aims to provide critical support for moderate- to high-risk youth transitioning back into their communities after confinement. This funding opportunity encourages collaboration among state agencies, local governments, Tribes, and community organizations to deliver comprehensive reentry services and assist youth in overcoming challenges related to recidivism. Applications are due by November 9, 2026, at 8:59 p.m. ET.

The OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support aims to fortify a national network of 61 multiagency task forces dedicated to combating child sexual exploitation facilitated by technology. This funding opportunity enhances training, prevention, and outreach efforts while fostering collaboration among law enforcement entities. Applications are due in JustGrants by November 9, 2026, at 8:59 p.m. ET, ensuring timely support for critical initiatives to protect children.

The CDC is offering funding to enhance collaboration among tuberculosis control programs and various partners in the U.S. This initiative aims to strengthen relationships with national TB control entities, federal agencies, academia, and community organizations. The goal is to promote health and quality of life by preventing, controlling, and eventually eliminating tuberculosis in the United States, building on previous funding opportunities.

The Advanced Rehabilitation Research Training (ARRT) Program aims to enhance the research capabilities of individuals with advanced degrees, focusing on disability and rehabilitation research related to employment outcomes. Funded by the US HHS Administration for Community Living, this grant offers a 36-month project period, supporting multidisciplinary training for researchers, including those with disabilities, to contribute to high-quality research in the field.

The Advanced Rehabilitation Research Training (ARRT) Program, funded by the US HHS: Administration for Community Living, aims to enhance the capabilities of individuals with advanced degrees in conducting high-quality research focused on health and function outcomes for people with disabilities. The program offers advanced training opportunities over a 36-month period, specifically targeting rehabilitation researchers, including those with disabilities, to foster multidisciplinary approaches in disability and rehabilitation research.

The Small Business Innovation Research Program (SBIR) Phase II aims to enhance technological innovation in the private sector, focusing on improving the lives of individuals with disabilities through research and development. Administered by the US HHS Administration for Community Living, this program supports small businesses in addressing the needs of these individuals. Grants are available for a 24-month project period, allowing projects to expand upon Phase I results to achieve greater commercial application and societal impact.

The SMART Scholarship-for-Service Program, managed by the Department of War, aims to enhance the U.S. military's technical workforce by offering competitive scholarships for STEM degrees. With a funding cap of $1.3 billion over ten years, the program prepares scholars for critical roles in national defense, ensuring a pipeline of skilled professionals. Since its inception in 2005, over 8,000 scholarships have been awarded, fostering a strong connection between education and service in defense-related fields.

The Prioritization Process Pilot Program (PPPP) Competitive Grant Program, funded by the DOT Federal Highway Administration, offers up to $26 million for innovative transportation planning in FYs 2024-2026. Grants of up to $2 million will support the development of transparent, data-driven prioritization processes for project selection in transportation plans, ensuring that funded projects deliver public benefits and meet community needs.

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

GAP Audit Reimbursement Cost Share

Through funding from the USDA AMS Specialty Crop Block Grant Program (#25SCBPSC1280), South Carolina growers can now get reimbursed for 90% of the costs associated with a GAP audit completed while funds are available. To help growers receive reimbursements faster, they may choose to receive two separate payments. A grower may submit Part I of the application as soon as they have paid the SCDA portion of the audit without having to wait on the USDA invoice. Then, once the grower has paid the USDA portion, they may submit Part II of the application to receive 90% of that amount as well. However, a grower may choose instead to submit both parts together to receive one larger payment. See examples below:

Example 1

Smith Farm submits a paid receipt from SCDA Fruit & Vegetable Inspections for $575 with Part I of the application and receives a check for $517.50 approximately four weeks later. ($575 × 90%)

Next, the Smiths receive the USDA invoice, pay $345 to USDA, then submit the paid receipt with Part II of the application to USDA. About four weeks later the Smiths receive a second check for $310.50. ($345 × 90%)

Example 2

Jones Farm is charged the same as the Smiths above but chooses to wait until they have paid both invoices to submit the application. In this case, they may submit both Parts I and II of the application at the same time. The Jones’ will receive one check approximately four weeks later for $828.

($575 + $345 = $920 × 90%)

Applicants must submit a complete application package including all of the following:

• Completed application with correct information
• A state vendor registration number
• Complete, detailed answers to the questionnaire included in the application (Note: This information impacts our ability to seek continued funding for this program).
• Your agreement to provide follow-up information regarding the impact of GAP certification (Note: This information impacts our ability to seek continued funding for this program).
• A copy of the paid receipt or other proof of payment for the reimbursement you are requesting. We will not send checks unless we have this.

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Cold Storage Cost Share Program

The South Carolina Department of Agriculture and South Carolina Specialty Crop Growers Association are pleased to announce continued funding for the Cold Storage Cost Share Program. Through the USDA Specialty Crop Block Grant Program, farmers who are members of the South Carolina Specialty Crop Growers Association may receive reimbursement up to $750 for the purchasing and installing up to two (2) Cool Bot cooler systems. Nonmembers may receive reimbursement up to $325, for installing one (1) Cool Bot cooler system. The Cool-Bot utilizes a traditional window-unit air conditioner, multiple sensors, a heating element, and a programmed micro-controller to direct your air conditioner’s compressor to cool the room to 36° F, without ever freezing up.

South Carolina Department of Agriculture

The South Carolina Department of Agriculture was established in 1879 to oversee and promote agriculture in the Palmetto State. With services as diverse as food safety inspections, entrepreneurship development, and the Certified South Carolina branding program, we help the state’s farmers and agribusinesses grow and prosper.

The mission of the South Carolina Department of Agriculture is to promote and nurture the growth and development of South Carolina’s agriculture industry and its related businesses while assuring the safety and security of the buying public.

Market Development Educational Conference Cost Share Program

The SC Specialty Crop Growers Association is partnering with the SC Department of Agriculture (SCDA) to promote the specialty crop industry through a cost share program that will assist growers in attending domestic industry trade show and educational conferences. Attendance at various trade shows and conferences will equip South Carolina’s specialty crop growers with the latest and most current research based educational information on topics such as pest management, sustainability, production practices, food safety, and regulatory issues, which are essential in expanding the specialty crop industry.

Through funding from the USDA Specialty Crop Block Grant, this cost share program will cover 50% of registration fees for attending a specialty crop-focused educational conference for up to 2 growers per company. The cost share will not cover costs of merchandise, travel, food, or lodging.

Reimbursements are available on a first come first serve basis until funds are depleted. A farm may submit their application and primary source receipts after each event or following the end of the conference season.

Graduation Rule

Growers cannot exceed more than two consecutive years in the program, although they can reapply after one year hiatus.

South Carolina Research Authority

SCRA is a public, non-profit corporation chartered in 1983 by the State of South Carolina. Its mission is to fuel South Carolina’s innovation economy by accelerating technology-enabled growth of academia, entrepreneurship, and industry. SCRA's vision is focused in becoming a leading catalyst in making South Carolina the top choice for technology-focused industry, entrepreneurs, investors, and academics.

SCRA supports its stakeholders in key technology sectors, which include but are not limited to, Advanced Materials/ Manufacturing; Life Sciences; Clean Tech, Sustainability, and Resilience, and Information Technology. SCRA grant funding is made possible, in part, by Industry Partnership Fund (IPF) contributions. Contributors receive a dollar-for-dollar South Carolina income tax credit, making it a no-cost way to create a direct, positive economic effect and job creation. 

Academic Matching Grant 

Managed by the Academic Innovations team, the objective of the Academic Matching Grant is to expand academic engagement in research and development by validating and advancing technology concepts towards the potential of a license opportunity, and/or company formation. Key milestones include: market opportunity and technical feasibility, in the IDEATION stage of startup development. 

Qualifying technologies are recommended by the institution’s Technology Transfer Office, or equivalent; Institutions are responsible for the technical review and prioritization of applications, and review opportunities with the Academic Innovations team. Based upon the review, SCRA will provide application materials and instructions. 

About Us

advancing the science of water ®

Who We Are

The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.

WRF was formed in 2018 through the integration of three highly respected research collaboratives: WateReuse Research Foundation, Water Environment Research Foundation, and Water Research Foundation. Separately, these organizations focused on research to support varied segments of the water sector—water reuse, wastewater and stormwater, and drinking water, respectively. Now a One Water organization, WRF delivers the research programming the sector needs to address the most pressing water issues holistically.

5425 - Assessing and Managing Manganese Behavior in Drinking Water Distribution and Premise Plumbing Systems

Grant Information

• Characterize spatial and temporal variability of manganese (Mn) concentrations and speciation in distribution systems and potential impacts in premise plumbing.
• Investigate Mn speciation and its influences on interactions with water chemistry, corrosion control treatment, and complexing agents, and assess implications for Mn occurrence, stability, and release in distribution systems and premise plumbing.
• Evaluate the relationships between Mn stability and release, including long-term legacy deposit mobilization, in relation to chemical, hydraulic, and biological processes in distribution systems.
• Evaluate strategies for mitigating Mn accumulation and release, including corrosion control treatments such as phosphate blends, and assess operational practices such as flushing and other system maintenance activities.
• Recommend monitoring strategies to identify system-specific risks, support detection of Mn accumulation, and inform responses to anticipated regulatory changes.

The USDA SBIR/STTR programs aim to enhance scientific excellence and technological innovation through federal funding, fostering a robust national economy. By supporting small businesses in addressing federal research needs, these programs encourage the commercialization of federally funded research. Specifically, the STTR program promotes partnerships between small businesses and research institutions, such as universities and federal laboratories, to advance cooperative research and development efforts.

The Technical Assistance and Training Grant Program by the USDA's Rural Utilities Service provides funding for essential technical assistance and training aimed at resolving water and waste management issues. This program supports applicants in preparing loan and grant applications, enhancing the operational efficiency of water systems, and ensuring compliance with best practices in facility management. However, grant funds cannot be used for duplicating existing services or for capital expenditures.

The Solid Waste Management Grant Program, administered by the USDA's Rural Utilities Service, invites applications for FY 2027 funding. This initiative aims to enhance solid waste management in rural communities through technical assistance and training. Eligible organizations can receive grants to develop sustainable waste management practices, addressing critical issues like water pollution and emerging contaminants, while promoting hazardous waste collection. This program supports operational improvements and capital financing applications to ensure long-term environmental health.

The HIV Prevention and Alcohol R61/R33 funding opportunity aims to advance innovative HIV prevention strategies through a phased research approach. The R61 phase focuses on developing and pilot testing interventions, addressing key implementation questions for diverse populations. Following successful milestones, the R33 phase expands testing of these interventions and explores their effectiveness and sustainability, particularly in relation to alcohol use and related health issues.

The NASA ROSES 2025: A.18 Geosphere program provides funding for research on solid-Earth processes across various scales. It aims to enhance understanding of the Earth's structure and dynamics, particularly in the core, mantle, and lithosphere. Key areas of focus include Earth Surface Properties, Crustal Dynamics, and Earth Interior. This initiative supports advancements in managing natural resources, assessing geohazards, and exploring the forces driving plate tectonics, ultimately contributing to improved hazard forecasting and mitigation strategies.

The Distressed Cities Technical Assistance (DCTA) Program provides competitive funding for eligible applicants to deliver technical assistance to local governments serving economically distressed communities of 50,000 or fewer residents. Selected awardees collaborate closely with HUD to enhance the capabilities of UGLG officials and staff, ensuring they effectively address community needs. Applicants may focus on broad HUD jurisdictions or specific areas as specified in the program's NOFO.