Best Greenville County Grants for Nonprofits in South Carolina

The Agriculture Innovation Center Grant Program aims to support Agriculture Innovation Centers by providing grants that facilitate technical assistance to agricultural producers. This initiative focuses on enhancing the marketing of value-added agricultural products, ultimately fostering growth in the agricultural sector. Funded by the USDA's Rural Business-Cooperative Service, this program is designed to empower producers and promote innovation in agricultural practices.

About Boeing

A leading global aerospace company and top U.S. exporter, Boeing develops, manufactures and services commercial airplanes, defense products and space systems for customers in more than 150 countries. Our U.S. and global workforce and supplier base drive innovation, economic opportunity, sustainability and community impact. Boeing is committed to fostering a culture based on our core values of safety, quality and integrity.

The Employees Community Fund (ECF) of The Boeing Company

One of the largest employee-managed funds of its kind in the world, the Employees Community Fund (ECF) of The Boeing Company has empowered employees to make a greater impact by pooling their tax-deductible donations for more than 60 years. Employee-led grantmaking committees at 20 Boeing sites provide combined employee donations to nonprofits in their communities through ECF grants.

Charitable or educational organizations can apply for grants from the Employees Community Fund (ECF) of The Boeing Company.

Puget Sound Chapter

The Employees Community Fund (ECF) of Boeing Puget Sound is a pooled fund consisting of recurring payroll contributions from generous Boeing employees. It funds local nonprofits that help thousands of families and individuals in the Puget Sound region where Boeing employees live and work.

ECF focus areas

ECF makes grants to 501(c)(3) Health & Human Service nonprofits such as food banks, job-training programs, shelters, transitional housing, mental health services, and low-income medical clinics. ECF seeks the direct client benefit of each grant to ensure that our employees’ contributions directly help those in need.

ECF funding criteria

ECF has two distinct grant categories – Supporting Grants and Capital Campaign Grants.

ECF of Boeing Company: Puget Sound Chapter Supporting Grants

Consideration is given to nonprofits/agencies that are performing well and are seeking to upgrade, replace or modify elements of their infrastructure.

• Supporting grants cannot exceed $50,000. The requested amount cannot be more than 10% of an agency’s gross annual revenue.
• Supporting grants will be considered only for agencies benefiting residents in the Puget Sound Region.
• Supporting grants help agencies continue to effectively provide services through enhanced direct client benefit by aiding them in procuring and/or paying for items such as:
  • Equipment (ex. office, kitchen, industrial, furniture, etc.)
  • Vehicles used to support clients and/or transport food and/or goods (cost of vehicle and accommodations, tax, and licensing only; operating expenses, such as insurance, fuel, etc. is not allowed)
  • Phone systems
  • Cell phones for direct client use
  • Remodels and/or renovations (must hold at least a 10-year lease or own the building)
  • Purchase or construction of new buildings
  • Computers or tablets for direct client benefit and/or use
  • Software for direct client benefit and/or use (ex. Augmentative and alternative communication (AAC) device)
  • Information Technology expenses, without which procured tools would not work
  • External improvements for client safety (i.e. security system, exterior lighting, improved ADA accessibility, new or refinished pavement or concrete)
• Supporting grants which are accepted must be spent as approved within nine (9) months.

Presser Foundation

Passionate about music, Theodore Presser wanted to give back to it. When he died in 1925, he had been widowed twice without any children. The bulk of his fortune was left to The Presser Foundation, which was formally established 14 years after his death. From 1995 to June 2021, The Presser Foundation gave more than $80 million to music organizations, undergraduate and graduate music students, and retired music teachers.

Originally, the Foundation sought to promote the causes of musical education and musical philanthropy by providing scholarships for promising students, supporting the construction of buildings for music organizations, and directing aid to retired music teachers. Over time, the Foundation has evolved to support a broad array of music genres, expand its grantmaking areas, convene its nonprofit partners at special events, and collaborate with fellow funders, while continuing to follow the original intent and wishes of Theodore Presser.

Assistance to Music Teachers

Theodore Presser, mindful of his own early struggles in the profession, was committed to the support of music teachers. He also felt a sense of gratitude for the thousands of teachers who were the primary customers of his music publication business. In 1906, he established the Presser Home for Retired Music Teachers in Philadelphia. When it was no longer practical to maintain an independent facility, the Foundation created the Assistance to Music Teachers Committee to carry on its basic mission of financial support for retired teachers with financial need.

Typically, the Foundation provides modest financial assistance and/or help with the cost of medical insurance. Awards are made to individuals living in the United States whose primary occupation was as a teacher of music. To be considered for Assistance, applicants must be nominated by a music institution for consideration. 

The Kelley Foundation

The Kelley Foundation was established by Robert and Judy Kelley and their daughter Marla. The Kelleys are native Oklahomans and longtime residents of Southern Oklahoma.

The foundation is primarily focused on humanitarian projects in Oklahoma, with an emphasis on Southern Oklahoma. Our mission is to develop and strengthen our community, state, and nation by providing essential resources to those in need.

The Kelley Foundation Grant

The Kelley Foundation is a private, charitable foundation, incorporated under the laws of the State of Oklahoma and operated exclusively for providing support through its gifts and grants to religious, charitable, scientific, and educational institutions which are qualified under section 501(c)(3) and which are not private foundations within the meaning of section 509(a) of the Internal Revenue Service Code.

About RWJF

At the Robert Wood Johnson Foundation, we take bold leaps to transform health in our lifetime and pave the way, together, to a future where health is no longer a privilege, but a right. We take our responsibilities seriously, and pledge to work in ways that reflect our values.

Connecting Champions for Diversity, Equity, Inclusion, and Belonging in the Health Professions

RWJF seeks to fund one lead organization or consortium to serve as a national network-weaver for diversity, equity, inclusion, and belonging (DEIB) in the health professions. The selected grantee will connect and support leaders, organizations, and institutions across the ecosystem, strengthening relationships, aligning strategy and communications, and facilitating shared learning and collective action. By building the connections and infrastructure needed for collaboration, the grantee will help advance belonging, accountability, and systems change across health professions education and healthcare institutions.

Achieving a healthcare system grounded in equity requires both a diverse health professions workforce and institutions committed to advancing diversity, equity, inclusion, and belonging (DEIB). While diverse teams improve quality of care and health outcomes, RWJF has learned that increasing representation alone is insufficient without addressing structural and institutional barriers that shape belonging, leadership, advancement, and accountability. Structural racism and other forms of systemic inequity continue to limit opportunity across the health professions education and healthcare institutions.

Lasting change requires not only supporting diverse leaders, but also strengthening connections among educational institutions, healthcare organizations, professional associations, accrediting and credentialing bodies, students, advocates, community actors, and others within the health professions ecosystem, whose relationships, actions, practices, and mindsets shape health outcomes for the communities they serve. These relationships create the support, trust, shared learning, and coordinated action necessary to advance DEIB and build a more equitable healthcare system. 

The State Recreational Boating Safety (RBS) Grant Program, administered by the US Department of Homeland Security's U.S. Coast Guard, aims to enhance safety and enjoyment on America's waterways. This federal program provides grants to designated state agencies to reduce boating accidents, injuries, and fatalities. Although not open to the public, it plays a critical role in ensuring safe recreational boating experiences by implementing effective safety measures, thereby promoting public welfare and environmental protection.

The Hispanic-Serving Institutions Education Grants Program aims to enhance the educational capabilities of HSIs through innovative teaching and community development initiatives. Funded projects will not only serve the Hispanic population but will benefit the entire student body, promoting inclusivity. This program encourages applications that integrate applied research with community outreach, fostering experiential learning opportunities for students. The initiative aspires to set benchmarks for educational excellence at regional and national levels.

The National Institutes of Health (NIH) is continuing support for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), which focuses on clinical trials and biomarker validation studies for neurological disorders. This initiative aims to foster innovation in neurotherapeutics by providing essential infrastructure and expertise. The program encourages the establishment of Clinical Coordinating Centers (CCC) and Data Coordinating Centers (DCC) to enhance collaborative efforts. Note that applications are not currently being solicited.

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

The Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center (DRIC), supported by NINDS, aims to enhance diagnostic capabilities for UDN participants. This initiative will foster collaboration among clinical networks and stakeholders to develop innovative diagnostic tools and strategies. The DRIC will also focus on the systematic evaluation of unresolved UDN cases, advancing genomic and non-genomic diagnostics, and discovering novel disease-associated genes. This forecast allows potential applicants to prepare and collaborate effectively for future projects.

The NIH Stroke Clinical Trials Network (StrokeNet) aims to enhance stroke treatment through regional clinical enrollment coordinating centers (RCCs). Supported by the National Institute of Neurological Disorders and Stroke (NINDS), this initiative promotes collaboration for clinical trials that focus on acute stroke treatment, prevention, and rehabilitation. While applications are not currently being solicited, this notice serves to prepare potential applicants for future opportunities in advancing stroke care.

The Undiagnosed Diseases Network (UDN) aims to enhance diagnostic excellence through multiple clinical Networks of Diagnostic Excellence (NODEs). These NODEs will operate as regional networks, leveraging partnerships with various healthcare facilities to provide participant-centered evaluations for complex conditions. They will also engage in research and training to improve diagnostic tools and strategies. This initiative encourages collaboration and aims to improve the overall experience and access for participants in need of specialized care.

The National Institutes of Health (NIH) is continuing its support for the NeuroNEXT initiative, which focuses on conducting clinical trials and biomarker validation studies for neurological disorders. This infrastructure aims to foster innovation and enhance the development of effective neurotherapeutics for both adult and pediatric populations. While applications for network clinical research sites are not currently being solicited, this notice allows potential applicants to prepare collaborative and responsive applications.

The Homeless Veterans' Reintegration Program (HVRP) aims to assist veterans experiencing homelessness by providing tailored employment services. This federal initiative focuses on helping veterans transition to stable employment through job training, case management, and connections to local supportive services. HVRP aligns with national priorities to enhance career outcomes for veterans, ensuring they receive the necessary tools and resources for sustainable employment and integration into the workforce.

Grants for Research About Urban Communication Issues

Since our launch in 2005, the Urban Communication Foundation has provided awards and grants to dozens of distinguished scholars, researchers, and journalists to recognize and support provocative work that contributes in significant ways to the discourse around urban communication issues.

While most of our recipients hail from academia and journalism, we also encourage submissions from other practitioners whose work will lend new insights into the discipline, raise broader awareness of related socio-political, economic, and cultural concerns, or influence public policy.

Gene Burd Grant for Research in Urban Journalism Studies

The Association for Education in Journalism and Mass Communication has partnered with the Urban Communication Foundation to create the Gene Burd Grant for Research in Urban Journalism Studies. The purpose of this annual grant is to stimulate research that explains, enlightens, inspires, and improves the practice and study of journalism and communication in order to advance our understanding of journalism in urban environments.

About

Our Story: Women Deserve More

At Women Founders Grant we are catalyzing a no BS movement for women to truly attain Financial Agency.

Women Founders Grant

If you have a dream, we want to support it. We are here to level the playing field and give you the guidance you need to turn that dream into a reality.

Our Grants

• $5,000 Grants on a rolling basis.
• No strings attached.
• This is our biggest differentiator. We know first hand how the folks who have the funds make you jump through unnecessary hoops. No hoops here.
• An Entrepreneur Business Yoda to mentor and coach you.
• GTM support to help you grow and get paying customers.
• On demand resources that guide you through your entrepreneur journey.

• Simply answer two questions on the application page.
• At the heart of our grants, there's no limit to your business dream. From pioneering scientists to artisan bakers, we encourage diverse passions and pursuits.
• So what truly matters is you—the woman or women driving the business forward. We value authenticity over corporate jargon; past winners have simply shared their stories - real passion and vision can’t be faked - so let your’s shine.
• We seek not only business acumen but also the fiery passion that fuels your entrepreneurial journey.

About the Foundation

Our Mission

Beyond Batten Disease Foundation was established to eradicate juvenile Batten disease by raising awareness and funds to accelerate research for a treatment or cure.

About Funding

BBDF is dedicated to collaboratively developing, funding, and managing fundamental, preclinical, IND-enabling, translational and clinical research to improve the lives of children and young adults with CLN3 disease. Since 2008, BBDF has been the largest funder of juvenile Batten (CLN3) disease research, ranging from basic discovery research to translation into therapies. To inform our research initiatives, BBDF gathers information from one-on-one meetings, broad group discussions, scientific peer-reviewed publications, conference proceedings, drug pipelines, and tailored merit reviews into the foundation’s decision-making processes. Input comes from across the Research and Development spectrum including academia, biotechnology, the pharmaceutical sector, and clinicians, caregivers, and patients.

Our research funding decisions are based on these research objectives:

1) Supporting basic research to discover new mechanisms of disease, targets, and treatments

2) Supporting projects which facilitate execution of clinical trials such as expanding patient registries

3) Identifying biomarkers and other innovative clinical endpoints

4) Supporting projects that de-risks pharmaceutical investments in Batten disease

Foundation-Directed Research

The largest portion of the foundation’s portfolio is directed research. The foundation fills gaps in juvenile Batten disease research by funding high-impact projects and breakthrough technologies that will lead to disease mitigation and cure.

BBDF’s Principal Scientist regularly interacts with leaders in research and development across the entire therapeutic pipeline for Batten, as well as for adult forms of neurodegeneration (e.g., Alzheimer’s and Parkinson’s disease), and other related rare genetic diseases. To supplement this dialogue, BBDF creates specialty boards and steering committees to lead the development of its projects. A specialty board typically comprises ~200 years of combined experience specific to the proposed activity.

Investor-Initiated Research (Applying for a research grant)

In addition to directed research, BBDF accepts and awards research proposals. Because great ideas do not follow a schedule, we do this on a rolling submission basis. All budgets are carefully reviewed along with the proposed body of work. Applicants may be asked to revise their budgets and/or allow BBDF to share a summary of the proposal with other funders for the purpose of gathering additional support. Sometimes, the foundation will offer the applicant additional funding to incorporate additional expertise or methods into his or her plan.

Our Mission

The Baughman Family Foundation aims to make an impact on our local communities by supporting organizations nominated by family members. The goal of the foundation is twofold: to make a meaningful impact on our selected charitable organizations and to encourage family members to become active in charitable giving.

Submission Guidelines

When submitting an application, please keep the following guidelines in mind:

The focus of the Baughman Family Foundation is on supporting local charities where the Foundation can make a direct, tangible impact on causes that matter to our family.

About

What is FOXG1 Syndrome?

FOXG1 syndrome is a rare genetic neurodevelopmental disorder caused by a mutation in the FOXG1 gene. FOXG1 gene is one of the first and most important genes for early brain development and when impaired, causes developmental disabilities as well as medical complexities, including epilepsy.

Every child born with FOXG1 syndrome is unique as FOXG1 manifests as a spectrum where symptoms and severity vary between individuals. Our patient data shows characteristics of children with FOXG1 syndrome include: non-speaking, non-ambulatory, experience seizures, feeding problems, cortical vision impairment, movement disorders, and developmental delays. Less-severely-affected FOXG1 children often present with (ASD) Autism Spectrum Disorder as FOXG1 is an autism related gene. FOXG1 syndrome is found equally among both females and males and is geographically more prevalent where diagnostic testing is more advanced. 

Our Story & Mission

When our children were diagnosed with FOXG1 syndrome, we were told there was nothing we could do. No treatments, no concerted research underway, no roadmap. Just a devastating diagnosis for a disorder few had ever heard of.

But we refused to accept that. 

Research Assets & Grants

FOXG1 Scientific Research Project Grants

The FOXG1 Research Foundation is providing grants to scientists to deepen the understanding of the biology of FOXG1 with the goal of identifying innovative therapeutic strategies and finding a cure.

For the next few years, these are the strategic focus areas:

• Experiments designed to understand when, where, and levels of FOXG1 needed for normal brain development in mice
• Experiments designed to understand the biophysical properties of FOXG1 mutations
• Experiments designed to gain insights into the molecular and cell biological pathways regulated by FOXG1  

Retina Research Foundation

Across the nation, there were only a handful of voluntary groups with the will and the means to tackle retinal disdorders. Retina Research Foundation, established in 1969, was one of those organizations. By the 1980s, RRF had become a voice for retina research in an effort to reduce the incidence of retinal disease, which was fast becoming the leading cause of blindness in developing countries.

Undaunted, the Foundation steadily raised funds each year for vision scientists who were nationally recognized for their work in retina research. Government funding for eye research increased dramatically, and the field of retina research matured. As this body of knowledge grew, RRF programs were expanded to include major awards that recognize established retina scientists and contribute to their ongoing research. The Foundation also developed scientific exchange programs to disseminate knowledge of the dramatic advances that were being made in the laboratory.

RRF Pilot Study Grants

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

RRF is currently welcoming pilot study grant applications for the 2027 grant period. Each grant application must be signed by the principal investigator and either their Department Chair or Dean of Research.

Sports Matter Mission

We believe that sports change lives. In addition to physical and mental health benefits, sports have the power to change our perspectives, our character and our communities for the better. This core belief has guided DICK’S Sporting Goods and The DICK’S Sporting Goods Foundation since the beginning – but not everyone has the same access to play. Through grants and other support, The DICK’S Foundation Sports Matter Program helps under-resourced 501c3 organizations, schools and community teams across all 50 states provide opportunities for youth to play sports.

Why It Counts

• Low-Income Kids Play at Half the Rate of Wealthier Peers
• Participation in Team Sports has Declined 4% Since 2017
• One in Three Kids Can't Participate in the Sports They Want 
• Number of Kids Playing Multiple Sports Has Declined

Sports Matter Program

We Believe Every Kid Deserves a Chance to Play

The Sports Matter Program focuses on supporting youth sports in under-resourced communities.

All grant applications are made subject to review of the applying organization’s reputation and activities, and its agreement to comply with applicable terms and conditions. 

The Emergency Citrus Disease Research and Extension Pre-Applications program, funded by the USDA's National Institute of Food and Agriculture, seeks innovative proposals to combat Huanglongbing (HLB) and its associated diseases. This initiative aims to ensure sustainable citrus production in the U.S. through collaborative strategies that leverage existing knowledge. Funded projects will focus on developing actionable solutions for growers to effectively manage and prevent HLB infections, ensuring the health of citrus crops in the near future.

The Tribal Colleges Extension Program Special Emphasis (TCEP-SE) aims to enhance community engagement through pilot projects at 1994 Institutions, targeting issues like agricultural productivity, food systems, and public health. This program is open to a wide range of Tribal colleges and universities, promoting workforce development and youth involvement in agriculture. By addressing local needs, TCEP-SE fosters community vitality and prepares the next generation of Tribal agriculture leaders.

The ROSES 2025: A.17 Hydrosphere program by NASA aims to enhance our understanding of Earth's water systems, focusing on Ocean Physics, Precipitation Science, and Terrestrial Hydrology. This initiative invites proposals targeting specific priorities within these disciplines to advance knowledge on water distribution and movement across the Earth. Proposals will undergo rigorous peer review to ensure transparency and scientific integrity, aligning with NASA's commitment to reproducible and collaborative research.

The US Department of Health & Human Services announces a competitive funding opportunity for the Head Start/Early Head Start programs across various states. This initiative aims to enhance services for low-income families and children, promoting their social and economic well-being. With approximately $818.3 million available, the program seeks to expand access to quality early childhood education, thereby strengthening community stability and prosperity. Interested applicants can seek further information through the OHS Operations Center.

The Residential Services for Unaccompanied Alien Children program, funded by the US Department of Health & Human Services, aims to provide safe and child-centered care for unaccompanied minors. This initiative supports organizations that can offer 24/7 services and are licensed to provide necessary care, including group homes and transitional foster care, particularly in areas near the U.S. southern border, ensuring the well-being of vulnerable children.

The Early Head Start Expansion and Child Care Partnership Grants aim to enhance early childhood services for low-income families across GA, NC, and VA. With approximately $7.7 million in federal funding, this initiative will provide comprehensive support to pregnant women, infants, and toddlers, fostering family stability and community prosperity. The program reflects the Administration for Children and Families' commitment to improving economic and social well-being through accessible, high-quality early education services.