Best Greenville Grants for Nonprofits in South Carolina

The Emerging Frontiers in Research and Innovation (EFRI) program by the NSF aims to support transformative research in wave-based computing, fostering significant advancements in foundational engineering knowledge. With funding opportunities including EAGER awards and four-year grants up to $2 million, EFRI-WBC encourages interdisciplinary collaboration and innovative approaches to address strategic technology priorities. Proposals should articulate their potential long-term impacts on national science and technology missions, promoting a new era in computing methodologies.

The NSF MPS Chemistry Research Programs support groundbreaking research in chemical sciences, encompassing areas such as chemical catalysis, measurement, imaging, and theory. This initiative encourages innovative proposals that can lead to transformative advancements, without the necessity of immediate commercial applications. Researchers interested in exploring foundational concepts that could shape the future of chemistry are invited to submit their ideas for funding.

The National Science Foundation's Engineering Directorate (NSF ENG) promotes groundbreaking research in chemical, bioengineering, energy, and transport systems. Key programs include Chemical Process Systems, Engineering Biological and Biomedical Systems, Energy, Water, and Resource Engineering, and Transport Phenomena. NSF ENG seeks innovative, transformative proposals that push the boundaries of foundational research, regardless of immediate commercial applications, and emphasizes diverse funding opportunities based on availability.

The MPS Materials Research Programs, funded by the National Science Foundation, aim to enhance the understanding of materials and their diverse applications. These programs cover areas such as biomaterials, ceramics, condensed matter physics, and electronic materials. With an emphasis on transformative research, NSF MPS encourages proposals that are innovative and foundational, without the necessity for immediate commercial outcomes, fostering long-term advancements in materials science.

The BJA FY 2026 Kevin and Avonte Program aims to reduce the injuries and fatalities of individuals with dementia and developmental disabilities who wander from safe environments. This funding opportunity supports law enforcement and public safety agencies in implementing locative technologies to track missing individuals and develop programs that enhance safety and facilitate rescues, ultimately ensuring the well-being of vulnerable populations.

The Cold Chain Grants for Emergency Food Assistance, funded by the Agricultural Marketing Service, aim to support eligible organizations in enhancing cold storage capabilities within the food supply chain. This initiative focuses on providing essential nutrition assistance to low-income individuals through subawards to food banks and nonprofit organizations. By investing in cold storage equipment, the program seeks to improve the management and distribution of food resources, ensuring that vulnerable populations receive adequate support.

The ONR FY27 Young Investigator Program invites cutting-edge research proposals in priority areas that align with the interests of ONR Program Officers. This federal funding opportunity aims to support innovative projects led by early-career researchers, fostering advancements in science and technology relevant to the Navy. Interested applicants can find detailed eligibility criteria and contact information on the ONR website, encouraging collaboration and engagement in impactful research.

The Surveillance and Case Control Study of Stillbirth and Birth Defects (SUCCSSBD) aims to enhance the quality of birth defects and stillbirth surveillance in the U.S. By modernizing data collection through electronic case reporting, the initiative seeks to improve data quality and timeliness. The study will focus on identifying risk factors for birth defects and stillbirths, addressing a significant public health issue that affects thousands of pregnancies annually. CDC funding will support three key components in this effort.

The Preventing Violence Affecting Young Lives (PREVAYL 2.0) initiative aims to provide multiyear funding for state and local health departments to implement violence prevention strategies for adolescents and young adults. Key focuses include enhancing data-driven decision-making, building capacity for evidence-based strategies, integrating youth mental health support, fostering multisector collaborations, and prioritizing the prevention of various forms of violence, ensuring comprehensive support for youth development.

PetSmart Charities

We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.

Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.

Adoption Growth Grants 

Purpose

Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.

Funding Support

Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:

• Staff positions supporting in-store adoption programs and events.
• Marketing and advertising for in-store adoption programs.
• Volunteer or foster support, incentives, and recruitment related to in-store adoption events.
• Event supplies, including containment and enrichment materials.
• Shelter software and technology needs.
• Vehicle repairs or transportation to adoption events.
• Innovative in-store adoption ideas and pilot programs.
• Other costs directly associated with facilitating PetSmart adoptions and in-store events.

There are two Cohorts under this funding: Cohort 1-  Accelerating in-store adoptions; and Cohort 2: Capacity Building.

Cohort 1- Accelerating in-store Adoptions

Applicants must have completed 500 or more adoptions in a PetSmart store in the U.S. within the last 12 months.

Preference will be given to organizations that demonstrate a clear plan to expand an existing in-store adoption program or introduce new in-store adoption models that will increase adoptions.

Four Required Steps

Applicants must complete all four required steps below before submitting a grant application:

• Step 1 - Watch the kick-off video and complete the Adoption Accessibility Questionnaire
• Step 2 - Confirm eligibility and connect with your Adoptions Grant Manager: After completing the questionnaire, you will receive an email confirming your eligibility. Eligible partners will be invited to a call with their Adoptions Grant Manager to discuss the grant opportunity, expectations, and potential fit.
• Step 3 - Engage your PetSmart store partners: Discuss your intent to apply, align on goals, and gain their commitment to support the success of your in-store adoption program.
• Step 4-  Submit your application.

Friends of NRA

Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.

Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.

Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.

Friends of NRA: Capital Improvement Grants

Any request to support a project that seeks to improve a facility is considered a capital improvement. This includes, but is not limited to:

• Range improvements
• Berm improvements
• Clubhouse/Classroom facility improvements
• Shelter structures/covered firing lines/pavilions
• Road improvements
• Commercial-grade trap machines (see section regarding trap machines, below)
• Any other permanent improvement to an organization’s property or facility

The Grant Program considers requests for certain trap machines to be a capital improvement to the facility. Specifically, requests for commercial grade trap machines that have a capacity of 300 clays and up.

PetSmart Charities

We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.

Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.

Adoption Growth Grants 

Purpose

Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.

Funding Support

Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:

• Staff positions supporting in-store adoption programs and events.
• Marketing and advertising for in-store adoption programs.
• Volunteer or foster support, incentives, and recruitment related to in-store adoption events.
• Event supplies, including containment and enrichment materials.
• Shelter software and technology needs.
• Vehicle repairs or transportation to adoption events.
• Innovative in-store adoption ideas and pilot programs.
• Other costs directly associated with facilitating PetSmart adoptions and in-store events.

There are two Cohorts under this funding: Cohort 1-  Accelerating in-store adoptions; and Cohort 2: Capacity Building.

Cohort 2: Capacity Building

Applicants must have completed at least one adoption in a PetSmart store within the last 12 months.

Preference will be given to organizations seeking to build a consistent, sustainable in-store adoption program. Applications should include a clear plan, with examples, for sustaining the program over time.

Four Required Steps

Applicants must complete all four required steps below before submitting a grant application:

• Step 1 - Watch the kick-off video and complete the Adoption Accessibility Questionnaire
• Step 2 - Confirm eligibility and connect with your Adoptions Grant Manager: After completing the questionnaire, you will receive an email confirming your eligibility. Eligible partners will be invited to a call with their Adoptions Grant Manager to discuss the grant opportunity, expectations, and potential fit.
• Step 3 - Engage your PetSmart store partners: Discuss your intent to apply, align on goals, and gain their commitment to support the success of your in-store adoption program.
• Step 4-  Submit your application.

About Us

For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers. 

By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.

Our Vision

The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.

Our Mission

Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.

Teacher Grants

Educator Enrichment Grant

The Educator Enrichment Grant funds teacher participation in off-campus professional development, including seminars, workshops, conferences, and externships. 

About Us

For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers. 

By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.

Our Vision

The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.

Our Mission

Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.

Student Grants

Evaluation Factors

Applications are reviewed based on:

The AACR June L. Biedler Prize for Cancer Journalism

Prize Summary

The AACR June L. Biedler Prize for Cancer Journalism was established by the AACR in 2015 to raise awareness of the critical role that the media play in educating the public about cancer and cancer research.

Funded by a major bequest to the AACR from cancer research pioneer Dr. June L. Biedler, a scientist, mentor, and former member of the AACR Board of Directors, this prize showcases outstanding examples of cancer journalism and recognizes individual professional journalists who have produced accurate, informative, and compelling stories that enhance the public’s understanding of cancer, cancer research, cancer advocacy, or cancer policy.

The prize provides an unrestricted cash award of $5,000 and a commemorative award.

Categories

Each submission may be considered for only one category, as selected by the candidate on the application form.

Applicants may submit in any of the following categories:

Prize Acceptance

Awardees will be able to accept the prize during the AACR Annual Meeting 2027 in Orlando, April 2-7, 2027.

The FY26 Spinal Cord Injury Research Program Clinical Trial Award supports innovative clinical trials aimed at significantly improving spinal cord injury treatment. This funding opportunity encourages collaboration by allowing two Principal Investigators, including an early-career investigator, to drive the research forward. Applicants must partner with at least two SCI community members, ensuring that the project is informed by lived experiences and community needs throughout its development and implementation.

The FY26 Spinal Cord Injury Research Program (SCIRP) Investigator-Initiated Research Award (IIRA) supports innovative research aimed at enhancing patient care and quality of life for individuals with spinal cord injuries. This award encourages collaboration, allowing an Early-Career Partnership Option for two Principal Investigators, where one must be an early-career investigator. Focused on impactful research from basic to translational science, this opportunity is crucial for advancing SCI knowledge and interventions.

The FY26 Melanoma Research Program Focused Program Award for Rare Melanomas supports multidisciplinary research initiatives aimed at addressing critical questions in rare melanomas. This award requires collaboration between an Initiating Principal Investigator and up to two Partnering PIs, with the inclusion of a rare melanoma survivor or patient advocate in the project team. Approximately $5.6M is allocated to fund two awards, each capped at $2.8M, over a maximum performance period of four years.

The Melanoma Research Program Melanoma Academy Scholar Award supports early career investigators within seven years of their initial faculty appointment. This unique virtual academy fosters collaboration among established researchers and Scholars, focusing on research and career potential in melanoma. With approximately $1.54M allocated to fund two Scholar Awards, each capped at $0.77M, the maximum performance period is three years, and funding is expected to be available until September 30, 2032.

The FY26 Melanoma Research Program Survivorship Research Award aims to enhance the well-being of melanoma survivors through innovative research. This funding opportunity supports studies that prioritize quality of life, involving melanoma survivors or their families as collaborators. With approximately $2.04M available, two awards of up to $1.02M each will be granted for research over a maximum period of three years. Applications must be submitted by September 30, 2027, to be funded with FY26 resources.

The FY26 Melanoma Research Program Idea Award encourages innovative and high-risk research to advance melanoma treatment. With a budget of approximately $5.6M for 10 awards, each grant can fund up to $0.56M over a maximum of 2 years. The program aims to support projects that establish proof of principle and generate preliminary data for future funding opportunities. Notably, preliminary data is discouraged, and applicants must receive an invitation to submit a full application after the pre-application stage.

The FY26 Melanoma Research Program Team Science Award promotes collaborative, hypothesis-driven research to enhance melanoma care. This funding supports multidisciplinary teams of two to three Principal Investigators (PIs) to tackle complex challenges in melanoma. With approximately $18.9M available, the program aims to fund nine projects with a maximum of $2.1M per award over three years. Awards will be made by September 30, 2027, using FY26 funds that expire on September 30, 2032.

The FY26 Military Burn Research Program (MBRP) Technology/Therapeutic Development Award (TTDA) aims to translate promising preclinical findings into burn products for clinical use in challenging environments. This award supports the development of both tangible products, like medical devices, and knowledge products that enhance health outcomes. A new Mentorship Option encourages collaboration between experienced researchers and junior scientists, fostering the next generation of leaders in military burn care research.

The FY26 Military Burn Research Program (MBRP) Discovery Award aims to support groundbreaking research in combat-relevant burn care. This award encourages innovative and exploratory studies that provide new insights and foundational data for future clinical research. The focus is on novel approaches that lay the groundwork for scientific advancements and product development in burn care, ensuring robust preliminary data generation for subsequent research initiatives.

The DoW Military Burn, Patient-Centered Research Award aims to enhance the implementation of burn care research into clinical practice for military settings. The FY26 program supports clinical trials and research that directly benefit burn patients in resource-limited environments, fostering collaborations between experienced researchers and junior scholars. This initiative addresses critical gaps in combat burn care, ensuring effective interventions and guidelines are developed and utilized in operational battlespaces.

Mission & Vision

Mission:

The Community Foundation of Southern New Mexico serves as a community resource, connects donors to needs, and supports charitable organizations in their work.

Vision:

A community connected to the resources it needs to thrive.

Your Community Foundation of Southern New Mexico (CFSNM) serves as a vehicle for people of all means to make a lasting impact on quality of life in our region now and in the future. Our organization is supported by a broad base of individuals, families, corporations, and institutions connected by the desire to improve Southern New Mexico. We manage over 300 endowments, including 48 non-profit organizational endowments in Southern New Mexico, and are home to over 40 scholarships and nine annual grant cycles. As a center for charitable giving we support the arts, feed the hungry, expand literacy, improve health, and support countless other meaningful causes in the twelve counties including: Catron, Chaves, Doña Ana, Eddy, Grant, Hidalgo, Lea, Lincoln, Luna, Otero, Sierra & Socorro. 

Apply for a Scholarship

Your CFSNM offers scholarships that support students from all walks and stages of life in pursuing various avenues of their educational and professional journeys. 

With a wide range of categories, your CFSNM offers scholarships for everyone including, but not limited to:

• BiPOC
• Students with disabilities
• LGBTQIA+
• Healthcare
• Volunteerism
• CTE, Trade, Vocational
• In-state and out-of-state
• All degree paths for undergraduate to post-grad
• Students returning to school

Good Samaritan Scholarship

To support students pursuing a degree in nursing, social work or certified nursing

The Juan Diego Guadiana Legacy Foundation Scholarship supports students from Las Cruces High School or Doña Ana County, especially those affected by cancer treatment or pursuing health-related fields. This scholarship is open to various backgrounds, including BiPOC and LGBTQIA+ communities. The foundation aims to empower students at different educational stages, ensuring they have the resources necessary to thrive in their academic and professional journeys.