Best Lee County Grants for Nonprofits in South Carolina

About AOTF

Established in 1965, AOTF is an independent 501(c)(3) charitable, scientific, and educational organization. We serve as the premier resource for occupational therapy research and scholarship, working alongside researchers, educators, practitioners, community partners, and students to build evidence-based practice that improves lives.

As the only foundation dedicated exclusively to advancing occupational therapy science, we bridge the critical gap between innovative research and real-world practice. Our work ensures that occupational therapy interventions are grounded in rigorous scientific evidence, ultimately improving outcomes for millions of people worldwide.

AOTF President’s Award

The President’s Award honors and recognizes Pi Theta Epsilon chapters that organize and implement outstanding scholarly activities. This award celebrates chapters whose events increase knowledge, develop professional skills, and help advance the occupational therapy profession.

Review Process: Applications are accepted on a rolling basis with an annual review beginning January 31. The national PTE Executive Board evaluates all submissions.

Multiple Awards: When appropriate, a second award may be considered to distinguish outstanding individual and interchapter accomplishments.

About AOTF

Established in 1965, AOTF is an independent 501(c)(3) charitable, scientific, and educational organization. We serve as the premier resource for occupational therapy research and scholarship, working alongside researchers, educators, practitioners, community partners, and students to build evidence-based practice that improves lives.

As the only foundation dedicated exclusively to advancing occupational therapy science, we bridge the critical gap between innovative research and real-world practice. Our work ensures that occupational therapy interventions are grounded in rigorous scientific evidence, ultimately improving outcomes for millions of people worldwide.

PTE Grant for Excellence in Interchapter Collaboration

The PTE Grant for Excellence in Interchapter Collaboration honors and recognizes Pi Theta Epsilon chapters that excel in creating meaningful partnerships with other chapters. This award celebrates collaborative efforts that support PTE’s mission and expand the impact of scholarly activities across multiple institutions.

This grant recognizes interchapter collaborations that:

• Support and advance the Pi Theta Epsilon mission
• Increase knowledge in occupational therapy
• Develop professional skills among members
• Contribute to the advancement of the OT profession
• Foster connections between chapters and institutions

Collaboration Definition: Activities organized and implemented by two or more Pi Theta Epsilon chapters working together toward a common scholarly goal.

Examples of Qualifying Collaborations:

• Joint events or conferences
• Collaborative workshops
• Co-authored educational or scholarly papers
• Virtual symposiums
• Multi-chapter research initiatives
• Regional or national networking events

The BJA FY 2026 Tribal Civil and Criminal Legal Assistance Program offers vital funding to support legal assistance for tribal members and justice systems in rural areas of the U.S. This initiative aims to enhance legal services where they are scarce, providing training and technical assistance for tribal courts and justice operations. Key focuses include veterans' legal aid, addressing Missing and Murdered Indigenous People, and implementing the Violence Against Women Act.

The BJA FY 2026 Justice Reinvestment Initiative aims to enhance state and local operations to effectively reduce crime and recidivism. This funding opportunity encourages state, local, and tribal governments to optimize resource allocation within the justice system, targeting urgent challenges through data-driven project proposals. By addressing areas such as law enforcement, prosecution, and probation, applicants can focus on strategies that maximize public safety and reduce the inefficient use of funds.

The Genesis Mission Graduate Fellowship Pilot aims to empower American scientists and engineers in the super intelligence (SI) revolution by inviting applications from U.S. higher education institutions. This initiative focuses on developing innovative doctoral training programs integrating SI with other scientific disciplines. Participants will gain valuable research experience through collaborations with DOE National Laboratories and industry, preparing them as the next generation of skilled Ph.D. scientists and engineers to tackle pressing national science and technology challenges.

The Heliophysics Low-Cost Access to Space (H-LCAS) program, under NASA, aims to foster innovative technologies and instruments for flight investigations utilizing sounding rockets, high-altitude balloons, and CubeSats. By advancing Heliophysics science, H-LCAS provides critical pathways for technology maturation and suborbital demonstrations. Proposals should align with the National Research Council's Decadal Strategy for Solar and Space Physics, emphasizing societal applications and supporting human exploration initiatives.

The OJJDP FY 2026 Emergency Planning for Juvenile Justice Residential Facilities program aims to enhance emergency preparedness in juvenile justice facilities across the country. This funding opportunity supports the development and implementation of comprehensive emergency plans that prioritize the safety of youth and staff, ensure effective communication with families, and maintain operational continuity during crises. By empowering facilities to improve their response and recovery capabilities, the program seeks to mitigate risks associated with emergencies, whether natural or man-made.

Rural Development in South Carolina

Strong rural communities are essential to South Carolina's long-term economic success. The South Carolina Department of Commerce partners with local governments and regional organizations to support community-driven development that strengthens infrastructure, expands opportunity and prepares communities for future growth.

Through strategic investments and targeted programs, S.C. Commerce helps rural communities build on their unique strengths while enhancing quality of place and economic competitiveness.

Rural Development Initiative (RDI)

The South Carolina Department of Commerce is pleased to announce the opening of the Rural Development Initiative (RDI) annual competitive grant program. Eligible county and municipal governments are invited to submit implementation-ready projects through a competitive application process designed to strengthen South Carolina's rural communities through strategic public investment.

The Foundation for Physical Therapy Research offers the Promotion of Doctoral Studies Scholarships for doctoral candidates, providing up to $15,000 annually. This scholarship supports students who have completed their coursework and exams, aiming to foster impactful research careers in physical therapy. Applicants may receive a total of $30,000 during their candidacy phase, with a maximum of $45,000 throughout their doctoral program. This initiative prioritizes academic excellence and alignment with APTA research priorities.

The National Institute of Allergy and Infectious Diseases (NIAID) aims to enhance its mission through the Implementation and Evaluation of Databases to Examine AIDS Consortium. This initiative merges clinical, genomic, and epidemiologic data to foster evidence-based research and implementation science. By leveraging advanced data science and AI technologies, the consortium addresses HIV morbidity and mortality, improving prevention and treatment strategies. This work aligns with the U.S. Ending the HIV Epidemic initiative, ensuring impactful contributions to public health.

The OJP FY 2026 Integrity in American Elections Grant Program aims to enhance election integrity across the United States. This initiative, supported by the US Department of Justice, focuses on empowering state and local prosecutors to effectively prevent and prosecute voter fraud and maintain the integrity of voter rolls. By safeguarding elections against illegal voting and registration practices, this program is vital for upholding public confidence in democratic processes and ensuring that every American's vote counts.

The Fiscal Year 2027 Counter Unmanned Aircraft Systems (C-UAS) Grant Program allocates $250 million to enhance public safety through advanced UAS Detection, Identifying, Monitoring, Tracking, and Mitigation technologies. This funding focuses on supporting law enforcement agencies in safeguarding critical infrastructure and public events, particularly the 2028 Summer Olympics and Paralympics in Los Angeles, designated as a National Special Security Event. The program aims to build national detection capacity and ensure effective interagency coordination.

The Institute of Education Sciences (IES) invites transformative research proposals aimed at addressing critical challenges in special education. The FY 2027 focus is on developing innovative preservice teacher education solutions that enhance the recruitment, training, and retention of both general and special education teachers. This initiative aims to significantly improve educational outcomes for students with disabilities, fostering high-quality instruction and scalable solutions to benefit future educators.

The Institute of Education Sciences (IES) is launching the From Seedlings to Scale (S2S) Grants program to foster innovative educational solutions. Focused on integrating evidence into policy and practice, the program invites Phase One applications under the Coordinating Systems to Translate Evidence into Policy and Practice (C-STEP) area. Projects must utilize AI and technology to enhance education systems, ensuring alignment with evidence-based practices for improved outcomes for students from prekindergarten to grade 12.

The FY 2027 – 2029 Broad Agency Announcement (BAA) by the National Marine Fisheries Service invites innovative research and educational projects that enhance NOAA's mission. This funding opportunity focuses on applied environmental and cultural resource research, technical assistance, and education to promote effective stewardship of public lands. Please note that the availability of funds is contingent on appropriations, and this announcement does not guarantee project funding or review beyond initial administrative checks.

The National Endowment for the Humanities (NEH) is inviting applications for the Public Humanities Projects program, aimed at enhancing public understanding of the humanities through exhibitions, historic site interpretations, and public lectures. For 2027, topics of interest include Western civilization, literature, the 250th anniversary of the American Revolution, civic education, and cultural literacy. This initiative seeks to foster civil discourse and engage communities in meaningful discussions.

The USEA Foundation has established the TEAPRO Grant (Training and Education in the Art of Pace and Riding in the Open), which is available to organizers, trainers, education groups and others to support opportunities for riders and horses to practice galloping, trot sets, and other forms of riding in the open as well as learn about fitness and conditioning for both horse and rider. The aim is to further education in these skills and to support many of the sport's stakeholders in doing so— riders, horses, trainers, organizers, coaches, clinicians, etc. Examples include funding for: a clinician to conduct a session on how to gallop horses in the open; a clinic where riders work to develop a feel for pace at walk, trot and canter over terrain; a seminar to educate riders on how to safely and effectively build the fitness level of their horse and themselves; portable steeplechase jumps that will be used to create a steeplechase course at one or more facilities; offsetting costs for the equipment required to accurately measure and set up a galloping or trot set track.Grant Funding: Grant funds will be awarded to address specific funding needs up to a maximum of $3,000 per applicant. Total awards per year shall not exceed $8,000.

The Bee Foundation For Brain Aneurysm Prevention (TBF) invites proposals that further the mission of reducing the number of deaths caused by brain aneurysms. Proposals directed at understanding the early detection, pathophysiology, genetic predisposition, or treatment will take priority. Proposals from a variety of disciplines (including but not limited to translational Neurosciences, Neurosurgery, Neurology, Radiology, Genetics) are encouraged and multidisciplinary proposals that illustrate a multi-faceted approach will be weighted highly.The purpose of this program is to promote novel approaches to the early detection and prevention of ruptured cerebral aneurysms, or early emergency and critical care treatment (excluding device therapies). We invite proposals that test an innovative hypothesis or develop new outcomes via interdisciplinary or translational research. Applications with more than one investigator must indicate how the different expertise of the co-investigators will contribute to the overall goals of the project.  Grant Funding:

• $20-25,000 total amount to be distributed, but not limited to only 1 awarded applicant
• Applicants may request up to $25,000

The Elizabeth M. Keithley, Ph.D. Early Stage Investigator Awards (EMKESIA) offers funding of up to $50,000 per year for early-stage researchers focused on hearing and balance research. Managed by the Hearing Health Foundation, the program encourages innovative projects and supports the next generation of scientists. Eligible applicants must hold relevant degrees and demonstrate a pathway to independence in their research careers, contributing to advancements in hearing health solutions.

Elizabeth Ratta, a brain aneurysm survivor and a Bee Foundation ‘share your story’ contributor is passionate about spreading brain aneurysm awareness and particularly in the populations they disproportionately affect- those who are Black, Hispanic and women. This research grant is named for Elizabeth’s grandma, Rita who had an unruptured brain aneurysm, but at a time when there was limited treatment and support.About Rita Skertich GrantThe Rita Skertich Grant is specifically intended to fund research topics that focus on prevention and treatment of brain aneurysms in the Black and Hispanic population and women; the populations most affected by brain aneurysms. African Americans and Hispanics are twice as likely to have a rupture compared to white Americans. Women are more likely than men (3:2 ratio) to have a brain aneurysm and 1.5 times more at risk of rupture than men. The research funded by this grant will support efforts to improve outcomes, accessibility and a greater understanding of discrepancies in the statistics for these populations with a focus on prevention. The preference is that this grant will be given to a Black, Hispanic and/or female researcher with other underrepresented research groups also considered.Grant Funding: 

• $15,000 total amount to be distributed, but not limited to only 1 awarded applicant
• Applicants may request up to $15,000

The Focused Discovery Awards (HHF-FDA) by the Hearing Health Foundation provide up to $50,000 annually for innovative research in hearing and balance. Targeted at early career investigators, these grants aim to foster groundbreaking projects that enhance understanding and treatment of hearing loss, benefiting millions. Applicants must demonstrate a strong research background and institutional support, ensuring that funds are directed towards high-impact projects that can lead to future funding from major research institutions.

The Focused Discovery Awards - Type 2 (HHF-FDA-2) provide funding of up to $50,000 for innovative research addressing hearing and balance issues. Open to investigators at any career stage, these grants aim to support new lines of inquiry in underfunded areas of otology. The Hearing Health Foundation encourages applications that demonstrate strong research training and institutional support, fostering advancements in hearing health for millions affected by related conditions.

The Expanded Discovery Awards (HHF-EDA) by the Hearing Health Foundation provide crucial funding up to $100,000 per year for innovative research in hearing and balance. These awards support both emerging and established investigators addressing specific topics in the field. With a focus on early career researchers, HHF-EDA aims to foster groundbreaking work that can lead to significant advancements in treatment and understanding of hearing loss, benefiting millions affected by these conditions.

The BJA FY 2026 Missing and Unidentified Human Remains (MUHR) Program aims to enhance public safety by improving the processes for reporting, transporting, and identifying missing persons and unidentified human remains. This funding opportunity supports efforts to locate missing individuals and address cases involving migrants, as authorized by Public Law 116-277. The program is part of the Office of Justice Programs' commitment to uphold justice and protect the rights of American citizens.

The SMART FY26 Support for Adam Walsh Act Implementation Grant Program aims to enhance sex offender registration and notification practices across jurisdictions in the U.S. By supporting the implementation of the Sex Offender Registration and Notification Act (SORNA), this grant facilitates the establishment of comprehensive sex offender registries, ensuring that states, territories, and federally recognized tribes comply with federal standards. This initiative also promotes interjurisdictional information exchange and helps maintain public safety.

The NIJ FY 2026 Research and Evaluation on Human Trafficking funding opportunity aims to support comprehensive research and evaluation projects. It focuses on preventing human trafficking, assessing the impact of federal policies, and enhancing services for victims. This initiative, led by the National Institute of Justice in partnership with the Office for Victims of Crime, seeks to generate insights that can inform better responses to human trafficking in the U.S.

The OJJDP FY 2026 Mentoring for Youth Impacted by Opioids and Other Substance Use program aims to provide high-quality mentoring services to youth affected by substance use. This funding opportunity supports various mentoring formats, including one-on-one, group, and peer mentoring, to assist those currently using substances or at risk due to familial influences. The initiative seeks to enhance the well-being of these youth through supportive relationships and guidance.