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Looking for grants for 501(c)(3) nonprofit organizations working in Lee County, South Carolina? Find the perfect grant for your nonprofit on Instrumentl.
9,000+
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$3.23B
Total funding
$5K
Median grant
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Hispanic Heritage Foundation
Established by the White House in 1988, the Hispanic Heritage Foundation—a 501(c)(3) nonprofit organization—continues to advance its mission through award winning programs that adapt to the needs, aspirations, and vision of our community while delivering a strong value proposition for the country.
HHF’s mission and programs have been recognized by The White House, US Congress, Fortune 500 Companies, US Army, other nonprofits, and even the Government of Mexico, in five areas of focus: education, workforce development, societal impact, and leadership, with culture serving as the cornerstone of its mission.
Youth Awards
The 28-year-old Youth Awards have recognized thousands of high school students from all 50 states, Puerto Rico, and Washington, D.C., for their achievements in the classroom, community, and focus on career paths in STEM fields, entrepreneurship, media, public service, and other categories.
Gold, Silver, and Bronze recipients are selected in each category and receive a one-time innovation grant to fund their college education or support a community service effort addressing a social issue. Additionally, one national awardee is selected in each category.
Once selected, recipients are celebrated in virtual ceremonies and become part of the LOFT (Leaders On Fast Track) Network, a collective of 300,000+ students and young professionals with access to mentors, resources, networking opportunities, workshops, symposia, summits, internships, and full-time positions with Fortune 500 companies.
The Dressage Foundation
The Dressage Foundation is a 501(c)(3) non-profit, tax-exempt organization, whose mission is to cultivate and provide financial support for the advancement of dressage in the United States.
In 1989, Lowell Boomer founded The Dressage Foundation (TDF) with a vision: to empower dressage across the country. Since then, we've awarded millions of dollars in grants, helping people across our sport, and across the country, achieve their dreams. From grassroots initiatives to high-performance endeavors, we aim to create a strong, inclusive, and vibrant dressage community.
We strive to cultivate dressage excellence by reducing some of the financial barriers of dressage training and education, and we believe that every aspect of our sport deserves help.
George Williams Young Professional Fund
The George Williams Young Professional Fund supports dressage professionals, ages 25-35, who are committed to the sport and have established businesses as instructors and trainers.
The George Williams Young Professional Fund was established in 2018 to honor his lifelong commitment to dressage. Applicants should have a strong desire to participate in continuing education opportunities, in order to provide higher-quality instruction to their students.
About
Macchia Family Foundation
Aims to assist those who cannot assist them selves, or who have attempted to better their own lives and/or the lives of their families but have come up just a little short.
About BHOF
For 40 years, the Bone Health & Osteoporosis Foundation (BHOF) has been committed to preventing osteoporosis and promoting awareness about bone health. Learn more about our organization.
Awards
Robert F. Gagel, M.D. Community Leadership Award
The Robert F. Gagel, M.D. Community Leadership Award recognizes a healthcare professional who has made outstanding contributions to improving osteoporosis care and increasing community awareness about bone health. This award will be presented annually to a healthcare professional residing and working in the United States or its territories.
The Executive Committee of the Bone Health and Osteoporosis Foundation’s (BHOF’s) Board of Trustees will review nominations and select the recipient.
The award winner will be notified and announced in May, in recognition of Osteoporosis Awareness and Prevention Month. The recipient will receive a plaque and a financial award (currently $1,000) to support community service efforts initiatives related to osteoporosis and bone health.
PetSmart Charities
We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.
Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.
Adoption Growth Grants
Purpose
Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.
Funding Support
Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:
There are two Cohorts under this funding: Cohort 1- Accelerating in-store adoptions; and Cohort 2: Capacity Building.
Cohort 1- Accelerating in-store Adoptions
Applicants must have completed 500 or more adoptions in a PetSmart store in the U.S. within the last 12 months.
Preference will be given to organizations that demonstrate a clear plan to expand an existing in-store adoption program or introduce new in-store adoption models that will increase adoptions.
Four Required Steps
Applicants must complete all four required steps below before submitting a grant application:
Friends of NRA
Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.
Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.
Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.
Friends of NRA: Capital Improvement Grants
Any request to support a project that seeks to improve a facility is considered a capital improvement. This includes, but is not limited to:
The Grant Program considers requests for certain trap machines to be a capital improvement to the facility. Specifically, requests for commercial grade trap machines that have a capacity of 300 clays and up.
PetSmart Charities
We’re proud to celebrate over 30 years of being the leading funder of animal welfare in communities across North America. Since 1994, we’ve granted over $600 million to change-making organizations that help transform the lives of pets and those who love them.
Our Mission: We make the world a better place for pets by investing in community partners that advocate and care for the well-being of pets and all who love them.
Adoption Growth Grants
Purpose
Adoption Growth grants drive lifesaving outcomes by supporting successful, sustainable in-store adoption programs, events, and results in partnership with PetSmart stores.
Funding Support
Funding may be used for costs associated with building or enhancing your organization’s adoption program in partnership with PetSmart stores, including:
There are two Cohorts under this funding: Cohort 1- Accelerating in-store adoptions; and Cohort 2: Capacity Building.
Cohort 2: Capacity Building
Applicants must have completed at least one adoption in a PetSmart store within the last 12 months.
Preference will be given to organizations seeking to build a consistent, sustainable in-store adoption program. Applications should include a clear plan, with examples, for sustaining the program over time.
Four Required Steps
Applicants must complete all four required steps below before submitting a grant application:
About Us
For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers.
By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.
Our Vision
The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.
Our Mission
Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.
Teacher Grants
Educator Enrichment Grant
The Educator Enrichment Grant funds teacher participation in off-campus professional development, including seminars, workshops, conferences, and externships.
About Us
For over three decades, the Hamilton Education Foundation (HEF) has been sparking innovation and expanding horizons within our classrooms. Since 1991, this community-powered non-profit has channeled more than $2.5 million from passionate individuals, local businesses, and forward-thinking organizations directly into the hands of Hamilton’s students and teachers.
By funding transformative workshops, creative projects, and classroom grants, HEF doesn't just support education—it inspires students to dream bigger, rewards academic excellence, and builds a stronger, more vibrant community.
Our Vision
The vision of the Hamilton Education Foundation is to assist in achieving creative and academic excellence for the 21st Century through funding activities and projects for students and educators in the Hamilton School District.
Our Mission
Our mission, in partnership with the community, is to fund, Enhanced, Extended, and Enriched learning opportunities for students and educators in the Hamilton School District.
Student Grants
Evaluation Factors
Applications are reviewed based on:
The AACR June L. Biedler Prize for Cancer Journalism
Prize Summary
The AACR June L. Biedler Prize for Cancer Journalism was established by the AACR in 2015 to raise awareness of the critical role that the media play in educating the public about cancer and cancer research.
Funded by a major bequest to the AACR from cancer research pioneer Dr. June L. Biedler, a scientist, mentor, and former member of the AACR Board of Directors, this prize showcases outstanding examples of cancer journalism and recognizes individual professional journalists who have produced accurate, informative, and compelling stories that enhance the public’s understanding of cancer, cancer research, cancer advocacy, or cancer policy.
The prize provides an unrestricted cash award of $5,000 and a commemorative award.
Categories
Each submission may be considered for only one category, as selected by the candidate on the application form.
Applicants may submit in any of the following categories:
Prize Acceptance
Awardees will be able to accept the prize during the AACR Annual Meeting 2027 in Orlando, April 2-7, 2027.
Friends of NRA
Friends of NRA is the National Rifle Association’s premier fundraising program, supporting the future of shooting sports. Since day one, Friends of NRA has been a 100% grassroots effort fueled by a united front to secure the Second Amendment and raise money for the shooting sports.
Committee volunteers are appointed to State Fund Committees to make recommendations for local grant funding in areas such as youth education, women-focused clinics, law enforcement training, hunter safety, range improvement, firearms and marksmanship training and safety. Recognizing the impact American youth has on the future of the shooting sports, State Fund Committees frequently recommend grants for youth programs, allocating the most significant portion of monies to this vital area.
Grant awards fund activities and support programs in the United States to promote firearms and hunting safety, to enhance marksmanship skills of those in the shooting sports, and to educate the public about firearms in their historic, technological and artistic context.
Friends of NRA State Fund Grant Program - South Carolina
The Friends of NRA State Fund Grant Program provides supplies, equipment, and financial support to a variety of qualified groups and programs at the local level; geared towards youth, women, law enforcement, veterans, the disabled, and the general public, including:
Grant funding must be used to further a charitable purpose as defined by the Internal Revenue Code under section 501(c)(3) and accompanying rules, regulations, and other IRS law and materials.
Edward E. Ford Foundation
The Edward E. Ford Foundation seeks to improve secondary education by supporting U.S. independent schools and encouraging promising practices.
Traditional Grant for Associations
These grants are made in response to requests that can range from $25,000 to $100,000 and that must be matched by additional funds raised by the association at least 1:1.
Associations seeking placement on a Traditional Grant Agenda should be prepared to specify the anticipated dollar value of their proposal when they request placement. This can be months in advance of the date the final version of the proposal will be due, depending on the length of the queue.
Traditional Grants are awarded based on the quality of the proposal and other considerations in terms of the association’s operation, but it does not identify certain areas of independent school work as favored. That is, you can seek guidance as to what sort of proposals have been funded in the past but association should identify their own greatest institutional need that they think the Foundation can help address.
Step-by-Step Process
American Academy of Family Physicians Foundation
The AAFP Foundation focuses on improving health for everyone, and your support makes an immediate impact on the good work we do—from leadership development and education scholarships to funding social and health care services.
The AAFP Foundation strives to create a sense of belonging through an inclusive environment that embraces the family medicine community by recognizing individual uniqueness and contributions to family medicine.
Richard D. Feldman, M.D. Student and Resident Essay Contest
Each year, the Center for the History of Family Medicine (CHFM) sponsors a contest to encourage medical students and family medicine residents to write scholarly essays relevant to the history of family medicine in the United States. The first-place winner will receive $2,000 and the second-place winner will receive a $1,000 award.
We encourage all to apply and are committed to developing scholarly essays relevant to the history of Family Medicine in the United States by medical students and residents who reflect the rich diversity of the specialty and the patients served.
American Brain Foundation
The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.
Next Generation Research Grants
The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.
McKnight Clinical Translational Research Scholarship in Cognitive Aging and Age-Related Memory Loss
This award aims to support young investigators in clinical studies relevant to age-related cognitive decline and memory loss. The award also recognizes the importance of rigorous training in clinical research and encourages young investigators to seek opportunities to establish future careers in the area of human cognitive aging.
Please Note: The focus should NOT be on a neurodegenerative dementia (e.g., Alzheimer’s disease); however, proposals that focus on the combined study of cognitive aging and neurodegenerative cognitive changes may be considered.
For the purpose of this scholarship, research is defined as patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance identification of age-related cognitive decline and memory changes. These may include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health outcomes research. Disease-related studies not directly involving humans are also encouraged if the primary goal is the development of therapies, diagnostic tests, or tools to mitigate age-related cognitive decline and memory loss.
American Brain Foundation
The American Brain Foundation funds research across the spectrum of the brain and nervous system, because it is our best hope for improving treatments, advancing prevention strategies, and discovering cures. Brain diseases, disorders, and injuries are interconnected. When we cure one, we will cure many.
Next Generation Research Grants
The American Brain Foundation’s Next Generation Research Grants (NGRGs) support early career investigators conducting high-quality research aimed at better understanding, treating, and curing brain diseases. These grants are offered in collaboration with disease-focused partner organizations and reflect ABF’s Cure One, Cure Many research philosophy: the belief that breakthroughs in one area of research accelerate progress across many others.
Lawrence M. Brass, MD Clinical Research Training Scholarship in Stroke
This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies related to stroke, vascular neurology, and neurocritical care.
For the purpose of this scholarship, research is defined as “patient-oriented research conducted with human participants, or translational research specifically designed to develop treatments or enhance diagnosis of neurological disease. These areas of research include epidemiologic or behavioral studies, clinical trials, studies of disease mechanisms, the development of new technologies, and health services and outcomes research.” Disease-related studies not directly involving humans or human tissue are also encouraged if the primary goal is the development of therapies, diagnostic tests, or other tools to prevent or mitigate neurological diseases.
Agnes McCarthy Caregiver Foundation
The Agnes McCarthy Caregiver Foundation is a 501(c)(3) not-for-profit charity that provides hope and relief to caregivers who care for a loved one with mental health conditions.
Caregiver Grant
Family caregiving has become a public health issue that receives inadequate recognition in our country. While it can be rewarding to care for our loved ones, it often comes with significant physical, emotional and financial costs to the caregiver. On average, caregivers spend over 25% of their own income to support their loved one and provide 32 hours a week in unpaid care.
AMCF currently offers a $500 financial relief grant to assist family members with unexpected expenses due to their caregiving role. If you are a family caregiver to someone living with a mood or psychiatric condition like depression, anxiety, PTSD, bipolar, schizophrenia, or other mental health/co-occurring conditions, you are not alone, and we welcome you to apply for a caregiver grant today.
Additional Information
About USA Track & Field Foundation Inc
The USA Track & Field Foundation was established in 2002. Our Foundation provides a means to attract and guide funds to new and innovative track & field programs, with an emphasis on providing opportunities for youth and elite athletes.
Mission:
To support the development of emerging elite athletes, while fostering integration within the broader track & field community. To facilitate the physical, educational, social and character development of youth track & field athletes and to help prepare them to mature and succeed in adult life.Team and Club SupportThe USA Track & Field Foundation may be able to provide support to certain Elite Track & Field / Running clubs in the US.
About
Building a community of journalists committed to better health care reporting.
We believe accurate, contextual and balanced health care reporting is more important than ever.
People depend on health care stories to make life-altering decisions every day.
AHCJ U.S. Health System Reporting Fellowship
This opportunity is for U.S.-based journalists.
Issues with the U.S. health care system are often obvious — from large swaths of uninsured residents and junk insurance plans, to high maternal mortality rates and preventable medical errors. But what is at the root of issues like these? What could an equitable health care system look like?
Through the U.S. Health System Reporting Fellowship, supported by The Commonwealth Fund, you can pursue a significant reporting project related to the U.S. health care system at the local, regional and/or national level.
This fellowship allows mid-career journalists to maintain their regular employment while working on a major project over a 12-month calendar year. You’ll pursue the projects with the support of your newsrooms or arranged outlets, which commit to publish or air the work.
We believe that issues of health equity impact every facet of the health care system, which is why we’re specifically interested in projects focused on health equity. This might include racial disparities within a community, gaps in public health inclusion, unstable housing, insurance access, food insecurity, violence as a health issue, how health care institutions or systems are applying a racial equity lens to their policies and practices or otherwise addressing inequities or disparities, or other examinations of systemic problems that have become so apparent over the last few years.
Guidance is provided by AHCJ mentors through customized seminars on health care systems, conference calls and email consultations. The fellowship covers the cost of attending the seminars and the annual AHCJ conference, as well as a $2,500 project allowance to defray the cost of field reporting, health data analysis and other project-related research. In addition, you will receive a $5,000 fellowship award upon the successful completion of the project.
About
Building a community of journalists committed to better health care reporting.
We believe accurate, contextual and balanced health care reporting is more important than ever.
People depend on health care stories to make life-altering decisions every day.
Awards, Grants, & Fellowships
Ambitious freelancers who want to tackle an in-depth reporting project often find that the fee from a potential publisher doesn’t come close to covering their costs and time. Grants and fellowships can fill that gap, but freelancers have to know about them in order to apply. In this section, the Freelance Center is compiling a list of non-AHCJ grants, fellowships and awards (for when the hard work is done).
Sunshine Award
Presented by AHCJ’s Right-to-Know Committee
AHCJ’s Right-to-Know Committee established the Sunshine Award at Health Journalism 2026 as a way to elevate the work of journalists like STAT’s Bob Herman who fight for government transparency. We plan to continue this tradition annually from now on. Award winners receive free registration and a one-night hotel stay for our annual conference, a free year of AHCJ membership, a trophy and a certificate.
Helen Frankenthaler Foundation Inc
The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.
Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.
Visual Arts & Education Grant
The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:
Helen Frankenthaler Foundation Inc
The Helen Frankenthaler Foundation supports the artist’s legacy through a variety of initiatives, including exhibitions, loans of artworks, research and publications, conservation, grants, educational programs for the public and the scholarly community, and the publishing of a catalogue raisonné. It is dedicated to promoting greater public interest in and understanding of the visual arts.
Established and endowed by the artist during her lifetime (1928-2011), the Foundation became active in 2013, on the closing of Frankenthaler’s estate. As the principal beneficiary of Frankenthaler’s estate, the Foundation maintains an extensive collection of her work in a variety of mediums, as well as her collection of works by other artists and original papers and materials pertaining to her life and work.
Cultural Resilience Grant
The Helen Frankenthaler Foundation supports public engagement with the visual arts through philanthropic, educational, curatorial, and research initiatives. It has expanded its grantmaking to sustain museums and visual arts institutions, supporting exhibitions, scholarship, and education across the field. The Foundation’s grantmaking priorities are currently organized across three areas:
Looking for Lee County grants for nonprofits?
Read more about each grant below or start your 14-day free trial to see all Lee County grants recommended for your specific programs in South Carolina.
What's the typical amount funded for South Carolina?
Grants are most commonly $74,506.
What's the total number of grants in Lee County Grants for Nonprofits year over year?
In 2024, funders in South Carolina awarded a total of 24,410 grants.
Among all the Lee County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.
1. Education
2. Philanthropy, Voluntarism & Grantmaking Foundations
3. Human Services
How is funding for Lee County Grants for Nonprofits changing over time?
Funding has increased by 22.06%.
How does grant funding vary by county?
Greenville County, Richland County, and Charleston County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Greenville County | $580,646,902 |
| Richland County | $413,417,941 |
| Charleston County | $355,724,083 |
| Spartanburg County | $325,246,878 |
| Pickens County | $159,596,081 |