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Looking for grants for 501(c)(3) nonprofit organizations working in Lee County, South Carolina? Find the perfect grant for your nonprofit on Instrumentl.
9,000+
Available grants
$3.23B
Total funding
$5K
Median grant
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Multiplex Platforms to Assess Indicators of Micronutrient Status, Inflammation and Infectious Disease
The Challenge
Although combined immunological measurement of several micronutrient biomarkers has been demonstrated, current methods still have important limitations. These include heterogeneity in the composition of standards and controls; inconsistent batch-to-batch performance of analyte-binding molecules; variable reactivity for some analytes, especially soluble transferrin receptor (sTfR); and a functional analytical range that is too narrow to cover the physiological values of some analytes, such as CRP. It would also be valuable to add bioindicators for vitamins B1, B2, B9 and B12, which may require binding molecules that recognize metabolites or proteins associated with deficiency, a specific vitamer (plasma methyl-tetrahydrofolate without reacting with folic acid), comparable reactivity across vitamers (several folate forms in red blood cells), or a specific carrier-protein form (holo-transcobalamin rather than apo-transcobalamin or haptocorrin for vitamin B12).
The improved assays must combine high analytical specificity, sensitivity and robustness with a functional analytical range matched to the physiological values expected in the target populations (women of reproductive age, including during pregnancy and lactation, preschool-age children and older adults). Assays must remain low-cost (no more than US$20 for all analytes measured in duplicate) and require very small sample volumes, preferably less than 10 µL of plasma or serum). The tests are intended for population surveillance rather than local clinical (point-of-care) use. They should be designed to run many samples in a single batch in a small number of national or regional reference laboratories. The goal is to reduce dependence on expensive, infrequent population surveys and on export of samples to specialized laboratories in high-income settings.
This challenge is structured around two alternatives, a minimum-scope approach and an optimistic-scope approach. Targets are aligned with the candidate Target Product Profile for this platform, and applicants will be held to the relevant performance, cost and instrument targets.
Every Kindness is a Gift
Dollar Tree Gift Card Program 2026
Every Kindness is a Gift is a gift card grant program made possible through the generosity of Dollar Tree and managed by the team here at Gift Card Bank. We are a nonprofit organization that specializes in the distribution of gift cards and our mission is to improve well-being and build financial stability by supporting people through their time of need.
Through Every Kindness is a Gift, nonprofit organizations and Title I schools located in the 48 contiguous states may apply to receive a grant of Dollar Tree gift cards.
Gift cards received through these grants are meant to be distributed directly to individuals and families in need. A primary goal of the program is to give gift card recipients the dignity of choice by empowering them to shop for what they need themselves. By putting gift cards directly in the hands of our neighbors in need, we are able to increase access to essentials like food, school supplies, paper products, cleaning products, and hygiene items.
In 2026, there will be two rounds of grant distributions. In each round, we will award a number of grants between $2,500 and $10,000.
Round One is a summer distribution. Gift cards awarded in Round One will arrive in late June, while kids are on break and back-to-school is around the corner. Round Two is a holiday distribution. Gift cards awarded in Round Two will arrive in early November, as the end-of-year holidays approach.
We know that these are times of year when budgets are tight. Through these gift card grants, we hope to connect individuals and families directly to the essential resources they need during difficult months.
Alzheimer’s Resource Coordination Center (ARCC)
Overview
The Alzheimer’s Resource Coordination Center (ARCC), located within the South Carolina Department on Aging, was established by state legislation in 1994. The Center’s goal is to serve as a statewide focal point for coordination, service development, information, and education to assist persons with ADRD and their families. The ARCC is guided by a Governor-appointed advisory council composed of representatives from state agencies, organizations, and caregivers who have a special interest in Alzheimer’s disease and related dementias (ADRD). The advisory council aids the ARCC in meeting its goals of:
The ARCC is staffed by the Dementia Coordinator whose role is to monitor the state’s service delivery system and work closely with the ARCC Advisory Council to develop a coordinated state-wide delivery system that caters to the needs of persons with ADRD, their families, caregivers, and communities. Additionally, the Dementia Coordinator is responsible for submitting an annual report to the Chairman of the Medical Affairs Committee of the Senate and the Chairman of the Medical, Military, Public, and Municipal Affairs Committee of the House of Representatives on the activities of the ARCC.
ARCC Grants
Each year, the ARCC receives $150,000 to award dementia-specific grants to community organizations to support respite, education, and innovative programs for individuals living with Alzheimer’s and related dementias, their families, caregivers, and communities. Grants are awarded on a 2-year cycle through a competitive selection process.
Since its establishment in 1995, the ARCC Grants Program has awarded over 388 grants to community organizations that provide services to individuals, families, and communities affected by dementia. These services include dementia-specific respite, adult day programs, and educational programs that support the medical community, colleges and universities, first responders, and the general public. The ARCC grants have enabled more than 7,717 individuals living with ADRD to access respite care services and provided education services to over 78,117 participants. Moreover, since 2021, ARCC grants have supported the implementation of 17 innovative programs. These programs include virtual training for family caregivers, in-home activities that promote sustainability and independence in daily living for those with dementia, and technology that helps locate and safely return those with dementia who may have wandered from home.
During the FY25 grant period (July 1, 2024 to June 30, 2025), a total of 10 ARCC grants were awarded, providing services across 14 counties.
The Wellness Within Reach initiative aims to bring high-quality, face-to-face healthcare directly to rural South Carolina communities through mobile units, crisis response teams, and community-based care sites This grant opportunity seeks proposals from eligible organizations to strengthen South Carolina’s mobile crisis response and expand community care sites.
The Rural Health Transformation Program (RHTP), established under the Working Families Tax Cuts Act signed into law on July 4, 2025, is a federal initiative led by the Centers for Medicare & Medicaid Services (CMS). This program is designed to help state governments strengthen healthcare access, quality, and outcomes in rural communities by transforming the healthcare delivery ecosystem. Through a focus on innovation, strategic partnerships, infrastructure development, and workforce investment, the RHTP aims to create sustainable improvements in rural health systems across the United States. The Shoring Up to Sustainability initiative aims to strengthen the operational and financial resilience of rural healthcare systems in South Carolina by investing in critical facility enhancements and delivering targeted masterclass training for rural providers.
The Vanguard
Remuseum announces The Vanguard, an award and accelerator for innovative leaders in the visual and performing arts, in partnership with the Doris Duke Foundation. The Vanguard’s $100,000 annual award will recognize up to ten leaders who are exploring new ways to strengthen arts institutions, and a year-long accelerator will help them refine, implement, and evaluate their ideas. The first award and accelerator of its kind, The Vanguard celebrates leaders who are ready to center the public in their work in new ways, building models for increased relevance and sustainability in the arts.
The Program
The $100,000 grant that accompanies each award will go to that leader’s institution, to support ideas developed in The Vanguard’s 12-month accelerator program. That program begins with a week-long retreat at Shangri La, the Doris Duke Foundation’s global center for culture and ideas in Honolulu, Hawaii, followed by a year of monthly coaching sessions, regional peer gatherings, and collaborative workshops, culminating in a public presentation of their work and findings to the broader arts community. The accelerator and its curriculum, tailored specifically for cultural leaders, has been designed by Jenny Larios Berlin, entrepreneur in the creative and tech sectors and Lecturer at MIT Sloan School of Management, and will be co-taught with Gregory Bunch, entrepreneur and Adjunct Professor of Entrepreneurship at the University of Chicago Booth School of Business, and will be advised by Ethernet Inventors Professor of Entrepreneurship Bill Aulet, Managing Director of the Martin Trust Center for MIT Entrepreneurship.
By year’s end, members of The Vanguard will have built an intellectual kinship with each other while modeling a spirit of innovative leadership for the field. Remuseum will continue evaluating and sharing their work as case studies for cultural organizations broadly, and future classes will continue expanding a Vanguard of leaders (10, then 20, and on) who build models of success for cultural organizations in the 21st Century, allowing arts & cultural institutions not just to survive but to support a stronger and more pluralistic civil society.
South Carolina Housing Trust Fund (HTF)
The South Carolina Housing Trust Fund (SC HTF) is a valuable resource for developing and maintaining safe, quality affordable housing for low to very low-income households within the state. Funding and assistance for eligible home repairs and supportive housing projects are provided through three core programs—The Home Repair Program, Critical Home Repair Program, and Supportive Housing Program. SC Housing administers the HTF program in partnership with other government organizations, non-profit sponsors and affordable housing developers. The HTF program also coordinates its efforts with other federal, state, and local housing assistance programs to achieve maximum benefit for participants.
The Critical Home Repair Program provide financial assistance to help low to very low-income homeowners with essential interior and exterior home repairs to correct life, health and safety issues so that they can live safely in their homes. These programs help to repair or replace major housing systems, including roofs, water heaters and HVAC equipment. It also covers home modifications, such as ramps, to provide accessibility for persons who are disabled. A home inspection is conducted to help identify any additional repairs that may be needed to provide the homeowner with safe and decent living conditions. The Sponsor then coordinates completion of the work with qualified contractors. The homeowner benefits by staying safely in a home that they can continue to enjoy for years to come. Local communities also benefit by maintaining the supply of affordable homes in their area.
The Leveling Up initiative aims to expand and integrate proven chronic disease management programs statewide, ensuring rural communities have access to comprehensive, coordinated care for serious and chronic conditions such as diabetes, hypertension, and sickle cell disease. Historically, these programs have been implemented in limited regions due to resource constraints, leaving rural areas underserved and often last to benefit from advancements in chronic care. This grant opportunity seeks proposals from eligible organizations to expand chronic disease programs.
The Connections to Care initiative aims to modernize and expand digital infrastructure across South Carolina’s rural healthcare ecosystem. This grant opportunity seeks proposals from eligible organizations to implement or enhance electronic health records (EHRs) and remote patient monitoring (RPM).
Crime Victim Assistance Grants
The mission of the Department of Crime Victim Assistance Grants (DCVAG) is to enhance South Carolina’s capacity to assist crime victims and to provide leadership in the promotion of justice and healing. Through grant funding, victims can receive services including:
Victims of Crime Act (VOCA)
DCVAG is responsible for the administration of four grant programs including the Victims of Crime Act (VOCA), a 1984-Public Law 98-473 established the Victims of Crime Act (VOCA) - Federal Fines, Fees, and Assessments
The primary purpose of VOCA is to support the provision of direct services to victims of violent crime. The program goal is to provide federal funding through grant awards to certified private non-profit organizations and public/government agencies for projects that will provide, enhance, improve, and expand direct services to victims of violent crime.
According to the 2016 VOCA Program Rule, direct services or services to victims of crime are defined as those efforts that (1) respond to the emotional, psychological, and physical needs of crime victims, (2) assist victims to stabilize their lives after victimization, (3) assist victims to understand and participate in the criminal justice system, or (4) restore a measure of safety and security for the victim.
Funding cannot be used for the investigation of crimes or collection of evidence to further the prosecution of crimes.
Who We Are
OneStar strengthens Texas communities by creating pathways for individuals and organizations to engage, connect, and accelerate their impact.
OneStar AmeriCorps VISTA Project
OneStar AmeriCorps VISTA Project places skilled individuals with a diverse range of backgrounds at nonprofits and agencies throughout the state of Texas. AmeriCorps VISTA members serve full-time for one year on capacity-building projects to advance your organization’s anti-poverty mission.
OneStar AmeriCorps VISTA Project places community-driven individuals with nonprofits & agencies throughout Texas on transformative projects focused specifically on building organizational capacity and infrastructure to alleviate poverty. Get the support you need to accelerate your efforts in volunteer management, marketing, community outreach, fundraising, program development, and more!
Capacity building activities include:
Who We Are
Thousands of your friends and neighbors make up Samaritan Health Services. We’re a nonprofit network of hospitals, clinics and health services caring for more than 290,000 residents in the mid-Willamette Valley and central Oregon Coast and portions of Marion and Polk counties. We work together to provide highly reliable and innovative medicine with world-class quality in a way that supports the values of the communities we serve. That includes caring for all people, regardless of your ability to pay.
Linn County- Samaritan Lebanon Community Hospital Auxiliary Scholarship
East Linn County students currently attending college and majoring in a medical field are invited to apply for the Samaritan Lebanon Community Hospital $1,000 Auxiliary Scholarship.
Background
The Fiscal Year (FY) 2025 Emergency Management Performance Grant (EMPG) Program is one of the grant programs that constitute DHS/FEMA’s focus on all-hazards emergency preparedness, including the evolving threats and risks associated with natural disasters. EMPG Program funding is awarded to the 56 states and territories using a population-based allocation methodology.
The main purpose of the program is to support the emergency management needs of state, local, tribal, and territorial governments, primarily through investments in planning, training, and exercise activities and to help cover the salaries of emergency management personnel.
About Foam Recycling
The process to recycle foam is like that of other recyclables. In the case of foam products, a special compactor – called a “densifier” – may be used in the processing of the material. Foam products are over 90% air, so densifying it allows the material to be transported more cost-effectively. To give you an example, a 48-foot truckload of baled foam polystyrene weighs only around 16,000 pounds, whereas a truckload of densified foam polystyrene weighs 40,000 pounds.
Innovative alternatives are being developed and deployed that are categorized as chemical recycling (vs. mechanical recycling). This will take the plastic resin back to its base state – in the case of foam PS, back to a styrene monomer. With chemical recycling, increased organic contamination will only impact the amount of foam for recovery (yield), but will not impact the recyclability of the plastic.
Foam Recycling Coalition Grant Program
Funding Source: Funding for the grant program comes from contributions from members of the Foam Recycling Coalition, a special interest group of the Foodservice Packaging Institute.
Grant Amounts: Funding amounts will be made on a case-by-case basis and will be dependent on equipment needs. The maximum amount per grant is $50,000.
Cash Match: No cash match is required, but additional costs by the grantee may be incurred for related items such as site preparation, provision of conveying system and electrical infrastructure, freight, and other installation costs.
Looking for Lee County grants for nonprofits?
Read more about each grant below or start your 14-day free trial to see all Lee County grants recommended for your specific programs in South Carolina.
What's the typical amount funded for South Carolina?
Grants are most commonly $74,506.
What's the total number of grants in Lee County Grants for Nonprofits year over year?
In 2024, funders in South Carolina awarded a total of 24,410 grants.
Among all the Lee County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.
1. Education
2. Philanthropy, Voluntarism & Grantmaking Foundations
3. Human Services
How is funding for Lee County Grants for Nonprofits changing over time?
Funding has increased by 22.06%.
How does grant funding vary by county?
Greenville County, Richland County, and Charleston County receive the most funding.
| County | Total Grant Funding in 2024 |
|---|---|
| Greenville County | $580,646,902 |
| Richland County | $413,417,941 |
| Charleston County | $355,724,083 |
| Spartanburg County | $325,246,878 |
| Pickens County | $159,596,081 |