Best Grants for Rare Diseases in Nebraska

With a mission to strengthen communities, US Bancorp Foundation provides Nebraska nonprofits with funding for economic and workforce advancement, safe and affordable housing, and community arts and culture. 501(c)(3) organizations, especially those led by people of color and addressing multiple pillars like work, home, and play, may be eligible to support community health and stability initiatives.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

Nonprofit 501(c)(3) organizations serving youth through health, education, development, or welfare programs in Nebraska and beyond can seek funding for direct services, advocacy, and enrichment initiatives. The Dan Paul Foundation provides up to US $15,000 for projects such as child welfare, early childhood development, environmental responsibility, homelessness, poverty, and refugee enrichment, which may benefit rare disease–affected children and families.

Early-stage, impact-first nonprofits and mission-driven for-profits in Nebraska and globally can apply for Draper Richards Kaplan Foundation support, with awards up to US $300,000 over three years for scalable social or environmental solutions. Organizations addressing underserved communities, including those working on rare or respiratory diseases, must show post-pilot traction, measurable impact, and strong growth potential.

Nonprofit and nongovernmental organizations using technology to address crisis response, education access, or economic empowerment in Nebraska and beyond can apply for Global Impact Cash Grants, with awards up to US $100,000. Grants from Cisco Systems Foundation help tech-enabled programs serving mostly economically underserved communities, including initiatives that may support rare disease-affected populations through education or economic stability.

Grants from State Farm Companies Foundation help Nebraska educational institutions, government programs, and eligible nonprofits fund safety, education, and community development initiatives. Organizations working on auto and home safety, disaster preparedness and recovery, affordable housing, job training, financial literacy, food insecurity, or K–12 and higher education programs may be eligible to apply.

Nonprofit cultural institutions in Nebraska offering arts, science, or STEAM education programs can access funding through the William Randolph Hearst Foundation, with typical awards of More than US $100,000. U.S.-based 501(c)(3) organizations with audited expenses above $2 million may be eligible for program, capital, or limited general support that could complement rare disease outreach or education efforts.

Nebraska 501(c)(3) and equivalent charitable organizations working in health, education, or community services can seek funding for programs such as healthcare access, food pantries, and STEM education. Labcorp Charitable Foundation supports initiatives including patient services for underserved populations and health-related programming, which may benefit organizations addressing respiratory and other rare diseases.

Nonprofits, social enterprises, schools, and public entities working on education, child health, or family economic stability for low-income urban youth in Nebraska can seek project or scaling support; awards are more than US $50,000. With a mission to expand opportunity, Michael & Susan Dell Foundation funds work in the U.S., India, and South Africa that measurably improves children’s lives and may benefit rare disease initiatives serving these populations.

Nonprofit charities running humanitarian, social, educational, environmental, or arts programs in countries where Roche operates, including Nebraska via its U.S. affiliate, may be eligible for philanthropic support. With a mission to strengthen communities, Roche provides accredited charities with funding for sustainable development projects, disaster response, youth science education, community health, and contemporary arts initiatives.

Nebraska health and human services organizations serving marginalized or vulnerable people can access funding through Semnani Family Foundation for programs in health care access, disease-related services, and humanitarian aid. Projects that address medical needs, child and women’s health, or social services for underserved communities may be competitive within this global funding portfolio.

Nebraska 501(c)(3) organizations working in charitable, scientific, medical, or educational areas can access funding through the Sidney Stern Memorial Trust to support programs serving U.S.-based populations. Eligible nonprofits with respiratory or rare disease initiatives may be competitive if they demonstrate strong management, broad impact, and meaningful contributions to community welfare.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

Nebraska nonprofits working on community services, environmental conservation, or peacebuilding can access funding through the Dudley T Dougherty Foundation to support their 501(c)(3) charitable programs. Organizations focused on rare or respiratory diseases may be eligible if their work intersects with these broader community or environmental priorities.

Nonprofit organizations, public schools, and local government entities near Georgia-Pacific manufacturing communities can seek funding for education, environment, entrepreneurship, and community enrichment projects in Nebraska and other eligible areas. Focused on strengthening local well-being, Georgia-Pacific Foundation invites community-based programs that align with its mission and operate within 30 miles of a GP facility.

Nebraska 501(c)(3) nonprofits located within 15 miles of a TJX store, distribution center, or office can seek funding for basic needs, at-risk youth enrichment, workforce readiness, and domestic violence safety programs. Grants from TJX Foundation help organizations serving vulnerable children and families, including those facing serious health challenges, which may benefit some rare disease support efforts.

Nonprofit 501(c)(3) organizations, public schools, and libraries in Nebraska seeking support for environmental or human services programs can apply for unrestricted grants from Lawrence Foundation, typically ranging from US $5,000 - US $10,000. Eligible organizations working on rare disease–related services within these areas of interest may benefit from either program or general operating support.

The Spark Good: Strengthening Community Local Grants program by the Wal-Mart Foundation empowers local organizations through grants ranging from $250 to $5000. This initiative aims to enhance community welfare by supporting diverse projects, including animal shelters and educational programs. Eligible organizations must have a verified Spark Good account, ensuring funds are allocated effectively to meet local needs and foster community development. Together, we can create lasting impacts through small yet significant actions.

U.S.-based 501(c)(3) nonprofits addressing basic needs, community vitality, or volunteer-driven causes can receive funding from Ameriprise Financial to support programs like hunger relief, shelter, adult self-sufficiency, and community development. Nebraska organizations working on economic stability or supportive services may be eligible, with priority for those engaging Ameriprise employees or advisors as volunteers.

The Nordstrom Community Grant focuses on supporting youth and families by providing over $1 million in grants annually. It aims to assist grassroots organizations that address essential community needs such as food, shelter, and clothing, as well as creating opportunities for economic mobility through mentorship and workforce development. Eligible organizations must be 501(c)(3) nonprofits located in areas where Nordstrom operates. Applications are encouraged for those meeting these criteria.

Nebraska 501(c)(3) nonprofits seeking project support in education, health care, social services, civic or cultural work, or environmental programs can access funding through Dr Scholl Foundation. Grants of US $5,000 - US $25,000 are awarded annually, with an online LOI and application required during the October 1 to March 1 grant cycle.

Nonprofit 501(c)(3) organizations and aligned for-profits can seek the Storytelling Grant to share the impact of their preservation, education, or wellness work, including in Nebraska. With a mission to support community-focused initiatives, Jesse W Couch Charitable Foundation provides more than US $50,000 to help capture and communicate meaningful change, which may benefit rare disease–related programs.

Nonprofit 501(c)(3) organizations in Nebraska working to improve community health, stability, and services can access funding through O'Reilly Automotive Foundation for project, general operating, or capital support. U.S.-based charities serving underserved people through health and social services, economic stability, workforce development, or disaster relief may be eligible, including programs intersecting with respiratory or rare disease needs.

Nebraska 501(c)(3) public charities can seek US $5,000 - US $30,000 for safety, workforce development, community vitality, or environmental sustainability projects that primarily benefit Union Pacific–served communities. Grants from Union Pacific Foundation help nonprofits, including independent emergency response organizations, expand direct services and capacity, with an emphasis on diversity, equity, and inclusion for underrepresented populations.

Nonprofit 501(c)(3) organizations in Nebraska serving youth and families through education, housing, food security, or environmental programs can apply for Chick Fil A Foundation’s True Inspiration Awards, with grants of US $30,000 - US $350,000. Programs supporting underserved young people, including those affected by rare diseases, may be competitive across the four award categories.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

Nonprofit organizations working to help disadvantaged people become self-reliant, including those addressing poverty, disability, social exclusion, or disaster relief, may be eligible for support, including in Nebraska. Nebraska health and rare-disease organizations can access funding through Gupta Family Foundation, with annual or multi-year awards ranging from US $5,000 - US $250,000 for smaller organizations operating in eligible countries.