Best Oconee County Grants for Nonprofits in South Carolina

The Foothills Community Foundation Grant supports 501(C)(3) non-profit organizations within Anderson, Oconee, and Pickens Counties, South Carolina. This grant focuses on projects that cannot proceed without foundation assistance, promote volunteer involvement, and demonstrate sustainability. Organizations are encouraged to collaborate to eliminate service duplication and must propose practical solutions to community challenges. Grants are limited and primarily aim to improve the quality of life for local residents.

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

The Indigo Hope Foundation offers grants to organizations in the Upstate of South Carolina, focusing on addiction, homelessness, at-risk youth, veterans, and first responders. They award between $250 and $100,000, prioritizing projects that demonstrate measurable results and address critical community needs. Eligible applicants must be 501(c)(3) tax-exempt or government units, with only one application allowed per grant period. The foundation emphasizes collaboration and favors faith-based organizations.

The Duke Energy Foundation offers Local Impact Grants to enhance the quality of life in South Carolina. Grants up to $20,000 support initiatives in vibrant economies, climate resiliency, and opportunity and inclusion. Eligible organizations must serve communities powered by Duke Energy and meet specific tax-exempt criteria. The foundation prioritizes projects that promote environmental sustainability and community development, while emphasizing non-discrimination and measurable impact.

The Piedmont Natural Gas Company Grant Program, part of the Duke Energy Foundation, supports community vitality through grants of $20,000 or less. Focus areas include vibrant economies, climate resiliency, and promoting opportunity and inclusion. Eligible organizations must have tax-exempt status and serve communities without discrimination. The foundation prioritizes measurable community impact and does not fund certain entities, including for-profits and religious organizations. Applications are accepted year-round on a rolling basis.

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.

The Spinks Family Foundation provides large grants of $10,000 and above annually to support non-profit organizations focused on education, food security, health, and mental health initiatives. Organizations must be 501(c)3 certified and demonstrate community impact with at least 500 volunteer hours. Applications are accepted from March 1 to March 30, and awards are announced by September 15. This initiative aims to empower nonprofits to effectively address pressing community needs.

The Spinks Family Foundation offers small grants to support non-profit organizations dedicated to improving community life in South Carolina. Eligible organizations must be 501(c)(3) certified, with a focus on volunteer engagement and community services. Applications are accepted on a rolling basis and reviewed quarterly, providing essential funding for initiatives in education, health, and food security. This philanthropic effort aims to foster strong, healthy communities and enhance the well-being of residents.

South Carolina Department of Commerce

From site selection to infrastructure improvement, we are here to help grow new and existing businesses.

SC Commerce promotes economic opportunity for individuals and businesses through initiatives like workforce training. As a national leader in foreign direct investment, the state extends its global reach with offices in Europe and Asia that help existing companies in developing export markets.

South Carolina Community Development Block Grant

The South Carolina Community Development Block Grant (“State CDBG Program”) is designed to aid units of general local government in improving economic opportunities and meeting community revitalization needs, particularly for persons of low- and moderate-income. The State CDBG Program has been funded through the State since 1982 by the U.S. Department of Housing and Urban Development (HUD) under the Housing and Community Development Act of 1974, as amended (Title I). 

CDBG Program Goals and Outcomes

The SC Department of Commerce seeks to improve the well-being of all South Carolinians in a manner that supports and enhances a high quality of life. The State CDBG Program supports the agency’s efforts to strengthen communities through revitalization and improvement of neighborhoods, public infrastructure, and the local economy. 

The three overarching goals of the HUD CDBG program are to provide decent housing, economic opportunities and a suitable living environment. Within the context of these goals, each project funded by the State must also meet one of three outcomes identified by HUD: affordability, accessibility, or sustainability. 

Local Match/Leveraging

CDBG projects are expected to leverage other public and private investments and serve as a catalyst for future development.

There must be a 10% match of the total CDBG request, unless otherwise approved, which can come from a variety of committed sources including other grants, loans, waiver of fees, public or private investments, and documented volunteer or in-kind contributions. Matching funds must be immediately available for the project at the time of application. 

Community Development Block Grant Categories

There are three broad grant program categories: Community Development, Business Development, and Regional Planning. The Community Development Program is further broken down into several subcategories to address infrastructure, community facilities, and local priorities.

Community Development Programs

Description

This program is designed to produce outcomes that improve citizens’ quality of life and create a competitive environment for jobs and investment by addressing priority community development needs. Activities should contribute to healthy, safe and sustainable neighborhoods and communities. These grants are designed to improve the quality of life for distressed and LMI communities. Community Development projects will compete within the following subcategories that have the same general submission requirements, except that the Ready to Go Program will not be funded in a competitive funding round.

Community Development Program Categories: Community Infrastructure; Community Enrichment; Local Priorities Program; and Ready to Go Program

Local Priorities Program

Outcome and Priorities

This program is designed to address unique local and regional needs and priorities for addressing those needs through community development, including projects that reflect priorities established in conjunction with the S.C. Department of Commerce Business Incentives & Community Development Division. Projects may reflect community development needs that are not typically funded through the other State CDBG programs and generally should not be funded by other HUD partner programs, such as HOME and NHTF (affordable housing), ESG (homelessness) or HOPWA (special needs). These funds will be used for alternative grant activities and partnerships that meet the community development needs of eligible municipalities. Local Priority projects could include historic preservation, innovation, energy conservation, parks, and trails/greenways. New or expanded public service activities are also eligible. Projects should leverage other funding or include local funding; impact identified needs and demonstrate strong community support while meeting a National Objective and all other requirements. 

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Patient Care Fund

The NAFC Patient Care Fund supports direct patient services that expand immediate access to care. This funding is designed to help NAFC members meet urgent patient needs by supporting clinical supplies, expanded services, contracted providers, transportation assistance, medication access, and other direct care resources.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Breast Cancer Screening & Prevention Initiative

The Breast Cancer Screening & Prevention Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to expand access to lifesaving breast cancer screening and prevention services for uninsured and medically underserved. Through this initiative, the NAFC will provide $30,000 grants to members to establish or strengthen breast cancer screening programs in alignment with evidence-based guidelines from the U.S. Preventive Services Task Force and the American Cancer Society. Funding will support activities such as improving patient identification and referral systems, increasing access to mammography services through partnerships or mobile units, strengthening staffing and technology capacity, and providing patient education and case management to ensure follow-through with recommended screenings. By enhancing early detection and preventive care, the initiative seeks to reduce barriers to care and improve health outcomes for women who might otherwise go without critical cancer screening services.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Food as Medicine Initiative

The Food as Medicine Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to address food insecurity as a critical driver of health outcomes for uninsured and medically underserved patients. Research continues to demonstrate the strong connection between food insecurity and poor health, including increased risk of chronic conditions such as diabetes, hypertension, obesity, and certain cancers. Through this initiative, NAFC will provide $20,000 grants to member free and charitable clinics to implement or expand food insecurity screening and patient-centered interventions that improve access to healthy food and nutrition education as measured by the US Household Food Security Module or Hunger Vital Signs and patient education focused on food as medicine for eligible patients in order to increase the percentage of patients with improved food security scores within one year of project implementation.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Medication Therapy Management (MTM) Initiative

The Medication Therapy Management (MTM) Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to improve medication access, adherence, and patient understanding among uninsured and medically underserved populations. Individuals without health insurance often face significant barriers to obtaining prescription medications and receiving the counseling necessary to manage chronic conditions effectively. Through this initiative, NAFC will provide $30,000 grants to member free and charitable clinics and pharmacies to establish or expand Medication Therapy Management programs aligned with recommendations from the American Pharmacists Association. Funding will support activities such as staff certification in MTM, development of standardized protocols, and patient education to help individuals better understand their medications, manage side effects, and support overall treatment plans. By strengthening pharmacist-led care and improving communication between providers and patients, this initiative seeks to enhance medication adherence, improve chronic disease management, and advance better health outcomes for vulnerable patient populations.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

Healthcare Access Initiative

The Healthcare Access Initiative, supported by the McKesson Foundation and administered by the NAFC, aims to expand access to essential healthcare services for uninsured and medically underserved individuals. Free and charitable clinics and pharmacies play a critical role in ensuring that patients who fall outside traditional healthcare systems can receive timely, high-quality care. However, many clinics face barriers related to staffing, care coordination, technology, and patient outreach that limit their ability to meet growing community needs. Through this initiative, NAFC will provide $20,000 grants to member clinics and pharmacies to strengthen programs that increase access to primary care, specialty services, and preventive care. Funding will support innovative and practical approaches that reduce barriers to care, improve patient engagement, and expand the capacity of clinics to serve vulnerable populations.

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

NCCF awards more than $530,000 in scholarships a year. 

Mary C. Dillon Scholarship

Academic Focus:

• Nursing

Award:

• $750

Established by the Dillon Family, this scholarship is awarded to a student whose primary residence is in Torrington and who pursues, or intends to pursue, a degree in nursing at an accredited university or college. Preference is given to applicants with a record of volunteering with the Red Cross or other health-related organizations. This scholarship is not financially need-based. (No FAFSA required)

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

NCCF awards more than $530,000 in scholarships a year. 

SVNA Educational Enrichment Program Scholarship 

Academic Focus:

• Health care professionals pursuing continued education in a health care field, except pre-med

Award Average:

• $10, 000 renewable up to 4 years

Consistent with the SVNA’s mission to provide the best home health, hospice and preventative care, this scholarship supports health care professionals pursuing continued education in a health care field who reside in Canaan, Cornwall, Goshen, Kent, Norfolk, North Canaan, Salisbury, Sharon or Warren. 

Through the generosity of fundholders and donors, NCCF has awarded more than half a million dollars in scholarships to assist students in Northwest Connecticut with the cost of higher education.

NCCF awards more than $530,000 in scholarships a year. 

Patrick Dillon Scholarship

Academic Focus:

• Unspecified 

Award:

• $750

Established by the Dillon Family, this scholarship is awarded to a student whose primary residence is in Torrington, is either a first-generation immigrant to the United States or is the child of a first-generation immigrant, and who attends, or will attend, an accredited university or college. This scholarship is not financially need-based. (No FAFSA required)

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Capacity Fund

The NAFC Capacity Fund supports investments that strengthen clinic and pharmacy infrastructure and organizational effectiveness. This funding is designed to help NAFC members build the systems, tools, and capabilities needed to operate more efficiently, improve quality, and expand their ability to serve patients over time.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Healthcare Services Expansion Fund

The NAFC Healthcare Services Expansion Fund supports the launch or expansion of clinical programs and new service areas that increase access to care for underserved patients. This funding is designed to help NAFC members introduce new services or grow existing programs that address unmet community health needs and improve access to comprehensive, patient-centered care.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Response & Emergency Needs Fund

The NAFC Response & Emergency Needs Fund is designed to address urgent and unforeseen challenges that threaten operations or patient access to care within NAFC member organizations. These organizations often operate with limited reserves, making them especially vulnerable to unexpected repairs, equipment failures, workforce disruptions, or community emergencies. This fund provides rapid, flexible support to help stabilize operations and ensure continuity of care for uninsured and underserved patients.

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Jean Bear Mullins Memorial Scholarship

In honor of our beloved wife and mother, who was lovingly known as Jean Bear to her children, we have started the Jean Bear Mullins Memorial Scholarship to help students from Washoe County who have been accepted to or are currently enrolled in a Physician Assistant program or Medical School program at an accredited college or university nationwide. We are so proud to be able to honor her legacy.

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

General Fred Michel Memorial Scholarship

You are eligible to apply for a scholarship if you:

• provide strong evidence of interest in aviation as a career
• are a senior graduating from a northern Nevada high school, or are enrolled in or accepted to an accredited institution of higher education (2-year, 4-year, trade school, or certificate program)
• are pursuing or plan to pursue a degree in a field related to aviation
• have a minimum 1000 SAT and/or minimum 20 ACT score
• have a minimum 2.75 GPA
• agree to maintain a minimum 2.5 GPA and submit an unofficial copy of transcripts at the end of each semester you are receiving an award

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Claudine Williams Harrahs LV Employee Scholarship

You are eligible to apply for the Claudine Williams Harrah’s LV Employee Scholarship if you meet all of the following requirements:

• your parent or legal guardian has been a full-time employee of the original Harrah’s Las Vegas property for three (3) consecutive years at grade L14 or below (including all H and S grades
• your parent or guardian continues to be employed by Caesars Entertainment either at Harrah’s Las Vegas or another Caesar’s property for three consecutive years on the date the application is submitted
• your family income shows a need for tuition assistance
• you are a high school senior or college student with a minimum cumulative unweighted 2.75 GPA
• you have a minimum 1200 SAT or 20 ACT score
• you agree to maintain a minimum 2.5 grade point average and provide a copy of your unofficial transcripts at the end of each semester you are receiving a scholarship for review prior to annual scholarship renewal

Community Foundation of Northern Nevada

Established in 1998 as a Nevada nonprofit 501(c) 3 Corporation, the Community Foundation of Northern Nevada has distributed more than $200 million in grants and scholarships from over 300 charitable funds to strengthen our Nevada home. 

Scholarship Program

The Community Foundation of Northern Nevada’s Scholarship Program is intended to help students cover the ever-increasing cost of tuition. Some of our scholarships are based on financial need, but others represent an award for achievement. These scholarships typically go to students who have excelled in an academic area or have shown they can balance academics, volunteer work, and extracurricular activities. There are also scholarships designated for students who have overcome adversity, students pursuing degrees in high-need areas, and adult learners outside the traditional college age group. Community Foundation scholarships can help cover tuition, books, and on-campus housing.

Alex Sevcsik Opportunity Scholarship

The Alex Sevcsik Opportunity Scholarship is open to students who are graduating seniors from the Academy of Arts, Careers, and Technology, or students who have received services from the Eddy House. Preference will be for students who are interested in pursuing Business or Automotive Technologies. Qualifying students will be planning to attend any 2- or 4- year college or university, community college, or trade school in or out of state.

NCCF awards more than $530,000 in scholarships a year. Scholarships and awards are made possible by NCCF Funds, established by generous individuals and families. 

Valerie Rose Pinnette Memorial Scholarship Fund

Award Average:

• $1350

Established by Ed and Rosalie Pinnette in memory of their daughter, Valerie. This scholarship is awarded to a graduating high school student who resides in and attends school in NCCF's 20-town service area. Preference is given to students pursuing a degree in environmental sciences.

Kieth and Serena Cockrell Scholarship

This program was established in honor of long-time HBCU and UNCF supporters Kieth and Serena Cockrell, who are passionate about education and paving the way for future leaders. Eligible applicants must be permanent residents of North Carolina and a high school senior graduating from any public, private, or charter high school in Mecklenburg County, Union County, or Cabarrus County during this current Spring 2026 term.

Renewable Up to $30,000 Over a Four (4) Year Period. Up to $7,500 Per School Year.

Dr. John and Mary Martin Scholarship Fund

This fund was established to honor Dr. Martin and Mrs. Martin’s service as educators. The fund shall provide scholarship assistance to support the college-going ambitions of graduating seniors of Grandview High School who aspire to teaching careers in the field of pre-K through grade 12 education. Preference shall be given to students who are underrepresented in their area of focus within the education field; for example, males of color in pre-school or elementary school.

Award

• $1,000