Best Operating Grants for Nonprofits

Toyota Battery Manufacturing North Carolina (TBMNC) Grants aim to enhance community well-being by investing in nonprofit organizations that focus on community sustainability, inclusive mobility, and workforce readiness. This corporate initiative seeks partnerships with qualified 501(c)(3) nonprofits, public schools, and municipal organizations in the Randolph and Guilford counties. By supporting programs with a long-term impact, Toyota fosters a culture of inclusion and aims to address pressing societal challenges.

The State of Nevada Aging and Disability Services Division is seeking partners to provide essential support services for older adults and caregivers. This initiative aims to help these populations maintain independence and engage actively in their communities. Special consideration will be given to low-income individuals and those facing unique challenges, including minority groups and those at risk for institutionalization. The funding opportunity underscores a commitment to dignified and meaningful living for all participants.

The NIDCD Early Career Research (ECR) Award (R21) provides support for emerging researchers focused on hearing, balance, smell, taste, voice, speech, or language. This award is designed to help scientists establish their independent research careers and is not intended for thesis or dissertation work. The funding can be utilized for various projects, including secondary data analysis and the development of new research methodologies, facilitating the transition to larger R01 applications.

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Team Schnak Strong Fund

The purpose of the Team Schnak Strong Fund is to provide funds to qualified individuals to cover expenses related to the treatment of childhood Type I Diabetes. Grant requests will be considered for children up to the age of 21. Full time students at Emporia State University or Flint Hills Technical College are eligible until the age of 24.

The Kuni Foundation's Imagination Planning Grant focuses on addressing the urgent need for quality, affordable housing for individuals with intellectual and developmental disabilities (IDD) in Oregon and Washington. With funding ranging from $15,000 to $75,000, the grant supports organizations dedicated to developing inclusive housing solutions. Eligible applicants include 501(c)(3) non-profits committed to serving the IDD community, ensuring that innovative and sustainable housing options are explored and implemented.

The Patient-Centered Outcomes Research Institute (PCORI) will announce funding for patient-centered comparative clinical effectiveness research (CER) studies focusing on rare diseases. This initiative encourages collaboration and aims to fill critical research gaps affecting approximately 30 million Americans with rare diseases. Applications can request up to $12 million over five years, including coverage for patient care costs. This funding opportunity is set to open on August 12, 2025, with a focus on addressing pressing patient-centered CER questions.

The American Academy of Audiology offers the Investigator Research Grant to promote essential research in audiology and balance health care. With a funding limit of $20,000 for one-year projects, the grant aims to support innovative research that enhances the evaluation and management of hearing and balance disorders. Eligible applicants must hold a doctoral degree in audiology or hearing science and be affiliated with a non-profit institution in the U.S. or Canada, fostering collaboration between academia and clinical practice.

Grants

We’re Here to Support You

HAF+WRCF grant funding supports charitable programs and projects in our region (Humboldt, Del Norte, and Trinity counties in California, and Curry County, Oregon). 

Phyllis Nilsen Leal Memorial Fund '26-27

This sponsor will help to administer the funds which are granted.

Louis Leal established this fund in honor of his wife, Phyllis Nilsen Leal. The Leal Fund was established to provide children suffering from cancer, or other sicknesses, something to lift their spirits during their treatment. This could be a piece of equipment, a tutor, books, toys, or other items and experiences that could lift the child’s spirits.

Recipients can receive a maximum of $2,000 per person per fiscal year. 

About

Macchia Family Foundation

Aims to assist those who cannot assist them selves, or who have attempted to better their own lives and/or the lives of their families but have come up just a little short.

• Assisting children and people in need
• Supporting social, educational and philanthropic programs that better peoples lives
• Providing a helping hand to those who need it

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

Society of Hospital Medicine: Junior Investigator Award

SHM’s Junior Investigator Award was created to recognize junior/early-stage investigators. Junior/early-stage investigators are defined as faculty in the first 7 years of furthest postgraduate training. Applicants must be a hospitalist and a clinician investigator or non-clinicians (i.e., a PhD) researching Hospital Medicine relevant topics. Nominations from mentors and self-nominations are both welcome. Applicants may request feedback about their applications after adjudication of the winner. The winner will present the Junior Investigator Award commendation talk (30 minutes) during SHM Converge.

The IUSE: Innovation in Two-Year College STEM Education (ITYC) program, funded by the National Science Foundation (NSF), aims to enhance STEM education at two-year colleges. This initiative encourages innovative projects that promote student success in foundational STEM courses. Eligible institutions can request up to $500,000 for three years, with an extra $100,000 for those without NSF funding in the last five years, facilitating a total budget of $600,000 for impactful educational projects.

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

SHM’s Awards of Excellence

SHM’s Awards of Excellence Program honors members who have made exceptional contributions to hospital medicine in a wide variety of categories: 

• Excellence in Research
• Excellence in Teaching
• Excellence as a Partner in Hospital Medicine
• Outstanding Service in Hospital Medicine
• Clinical Leadership for Physicians
• Clinical Leadership for Nurse Practitioners/Physician Assistants
• Excellence in Humanitarian Services
• Excellence in the Care of Vulnerable Populations
• Excellence in Teamwork

Society of Hospital Medicine (SHM)

The Society of Hospital Medicine (SHM) is dedicated to promoting high-value care and achieving optimal outcomes for acutely ill patients. As part of this mission, SHM seeks to address inequities in acute patient care and contribute to a greater dialogue on this important issue. As the home for hospitalists, SHM activates and engages our community to

• Advocate for our specialty, our members, and the diverse patients we serve.
• Promote high-value care and optimal outcomes for acutely ill patients.
• Meet the evolving educational needs of a dynamic specialty.
• Cultivate an inclusive community for hospitalists and support career growth and wellbeing.
• Advance the research and innovation of healthcare delivery, quality, safety, and experience across the care continuum.

SHM’s Excellence in Teamwork Award

This award is presented in recognition of exemplary quality improvement initiatives in hospital medicine that engage the full patient care team. The award is intended to highlight outstanding team approaches to implementing interventions that improve patient care and safety but is particularly interested in projects related to the core competencies in hospital medicine and SHM’s quality improvement resource rooms. 

Recipients of the Excellence in Teamwork in Quality Improvement Award receive recognition at SHM Converge 2026 and complimentary registration for up to 4 team members.

The Student Research Grant in Audiology, offered by the American Speech-Language-Hearing Foundation, supports doctoral students conducting research in clinical and rehabilitative audiology. Up to three grants of $2,000 each are available for eligible students enrolled in accredited programs in the U.S. This initiative honors the legacies of Ira Ventry and Brad Friedrich, who made significant contributions to the field of audiology. Interested candidates must submit proposals for research projects to be initiated in this vital area.

Batten Disease Support, Research, and Advocacy (BDSRA) Foundation

BDSRA is dedicated to funding research for treatments and cures, providing family support services, advancing education, raising awareness, and advocating for legislative action. Founded in 1987, by parents seeking to build a network for those diagnosed with Batten disease, BDSRA is now the largest support and research organization dedicated to Batten disease in North America. BDSRA believes that to effectively unravel the mysteries of Batten disease, the worlds of medical science, research, and families must work together toward a common goal: discover treatments and cures while assuring a better quality of life for those living with the disease.

Batten Family Help Grant

The BDSRA Foundation is committed to supporting families of all CLN types in all aspects of their fight against Batten, including the financial challenges they face. BDSRA understands that families in our community caring for people with Batten disease are often faced with financial challenges that further interfere with their well-being.

We offer grants to help cover the costs associated with battling Batten disease, such as emergency travel, loss of employment, hospital bills, and other challenges our families might face.

31Heroes

On August 6, 2011, a tragedy shook the military community and Americans everywhere. In a single instance, America lost 30 military service members, many of whom were members of the Navy SEAL community—and one military K9– when a CH-47 Chinook helicopter, call sign Extortion 17, was downed in Afghanistan.

Established to honor the 31 Americans killed in action on August 6, 2011, 31Heroes serves to impact the lives of our nation’s heroes and their families, while remembering the fallen, through athletic endeavors and competitive fundraising events.

Our Mission: The mission of 31Heroes is to raise money and awareness through social and athletic events to support the families of Extortion 17 and honor their legacy by funding treatment for Veterans suffering from mental health issues.

Our Focus

Our goal is to create opportunities for the families of Extortion 17 to create healthier lifestyles and to provide financial relief in times of need. We consider it our responsibility to make a positive impact in the lives of each family. Whether through grants we provide, or through partnering with other non-profit organizations that offer programs or services that we do not, we are devoted to the families and creating a legacy the men of Extortion 17 would be proud of.

Guidelines

• Individual limits will not exceed $3750 annually
• Family Grants range from $750 to the maximum range of $1500
• Family members must submit an online application for consideration
• Applications may be submitted at any time during this funding cycle
• Priority and funding will be based on the Primary Next of Kin list

Lifestyle Grants

Lifestyle Grants are aimed at improving health and lifestyle via physical fitness, nutrition, holistic treatment, etc. Limit for this grant is $1500

The Blue Cross and Blue Shield of Minnesota Foundation's Healthy Start Grant Program aims to enhance early childhood care and education by funding tax-exempt nonprofits, Tribal Nations, and fiscally sponsored groups in Minnesota. With a total of $2 million over two years, grants of up to $100,000 per year will support initiatives to improve access to quality care, screenings, and family support services, ultimately addressing health inequities and fostering healthy development for vulnerable children.

The Museum Grants for African American History and Culture (AAHC) program, funded by the Institute of Museum and Library Services, aims to enhance the capacity of African American museums. This initiative supports professional development for museum staff and promotes accessibility to collections at these institutions and HBCUs. By fostering institutional growth, the program plays a vital role in preserving and showcasing African American history and culture through museum initiatives.

About StopWasteStopWaste is a public agency serving the 1.7 million diverse residents of Alameda County. Formed in 1976, we work on behalf of 17 member agencies—the County, 14 cities, and 2 sanitary districts—committed to advancing environmental sustainability and building healthy, equitable, climate resilient communities in Alameda County.Vision: An Alameda County in which people thrive and are empowered to utilize resources and energy in ways that are good for the health of our communities, our local economy, and the planet.Edible Food Recovery Program GrantsThe Edible Food Recovery Program (EFRP) Grant provides operational funding up to $30,000 to support Alameda County edible food recovery organizations that recover and redistribute donated surplus edible food to address food insecurity and nourish communities in the county. Funds are available to nonprofit organizations that facilitate the recovery and re-distribution of surplus edible food from business donors or other food recovery partners. 

The program prioritizes the funding of organizations that work to prevent the wasting of nutritious, culturally appropriate food, and ensure equitable, dignified distribution to underserved communities.  

The Cooperative Development Fund Grant supports cooperative development, research, and technical assistance for cooperatives focused on seniors, international development, and affordable housing. Grants, typically ranging from $20,000 to $30,000, are awarded once a year, with a two-stage application process: a concept paper followed by a full proposal for selected applicants. Up to two grants are awarded annually, with decisions announced shortly after the Advisory Board meeting in January.

The Sidney R. Baer, Jr. Foundation offers Clinical Research Grants to support advancements in the treatment and understanding of schizophrenia and bipolar disorder. Focused on organizations with IRS tax-exempt status, these grants aim to enhance mental health services and research. By funding initiatives in cognitive and behavioral sciences, the foundation seeks to improve the lives of those affected by serious mental illness, ensuring they receive the support and resources necessary for a better quality of life.

The Multiple Sclerosis Clinical Care Physician Fellowship: Pediatric Care, offered by the National Multiple Sclerosis Society, aims to enhance the training of physicians in providing specialized care for pediatric patients with MS. This one-year post-residency program emphasizes direct patient care and multidisciplinary collaboration. Participants will learn under the supervision of MS specialists, gaining essential skills to improve clinical practices and contribute to the MS community, ultimately leading to better outcomes for those affected by this condition.

The Homelessness Resolution Program (HRP), previously known as Emergency Solutions Grants (ESG), is administered by the Colorado Department of Local Affairs. This program aims to prevent homelessness and assist individuals and families at risk of homelessness by providing essential resources and support. HRP enhances access to housing, operates low-barrier emergency shelters, and offers vital social services to those in need, ultimately striving to connect participants with permanent housing solutions.

The AACR-Torrey Coast Foundation Transpacific Gastric and Esophageal Cancer Research Partnership Grant supports innovative research on upper gastrointestinal malignancies, which are responsible for over one million deaths globally in 2023. This grant encourages collaboration between U.S. and Asian institutions, focusing on resistance, metastasis, and novel treatment strategies. Proposals should detail plans for clinical translation and are open to researchers at all career stages, especially those new to upper GI cancer research.

The Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center aims to enhance diagnosis and research for individuals with undiagnosed diseases. This initiative focuses on engagement, education, and innovative diagnostic approaches. The center will oversee recruitment, participant support, and data management while fostering collaboration among various stakeholders. NINDS seeks proposals demonstrating the necessary infrastructure and partnerships to ensure effective implementation of the UDN's mission and transfer successful diagnostic methods into mainstream healthcare.

The Cape Cod Healthcare Community Benefits Program offers annual strategic grants aimed at enhancing healthcare access and quality for Cape Cod residents. This initiative supports non-profit organizations addressing unmet health needs, focusing on the financially disadvantaged and underserved populations. Through a competitive grant process, organizations can propose projects that promote health equity and improve physical and mental health in Barnstable County, aligning with the findings of the Community Health Needs Assessment.

About

Intermountain Health is the largest nonprofit health system in the Intermountain West. We are dedicated to creating healthier communities and helping our patients thrive.

Community Health Investment Program

Platte Valley Hospital provides grant opportunities through the Community Health Investment Program (CHIP). The grant is meant to assist organizations with programs that improve the health of our community, especially for our low-income residents. Your grant application must show how you will impact the health of your target population. To be considered for a CHIP grant, your organization must meet most if not all, of these criteria:

• Support the mission of Platte Valley Hospital, “Helping people live the healthiest lives possible”
• Serve a demonstrated need in the community
• Proposals that involve collaboration with other community providers and organizations that are directly or indirectly involved with community health concerns will receive priority
• Have a reasonable financial request.