Best Puerto Rico Grants for Nonprofits

The NACD Technical Assistance Grants program, in partnership with NRCS, has been enhancing conservation district support since 2018. By funding staff hires, it aims to improve service for agricultural producers and address conservation workload challenges. The initiative focuses on outreach, education, and civic engagement to empower local communities, promote sustainability, and support historically underserved producers in implementing conservation practices, thereby fostering both individual and community resilience.

This funding opportunity aims to address health and healthcare disparities in non-communicable and chronic diseases across Latin America. It encourages innovative, multi-disciplinary research focused on clinical epidemiology and public health policy evaluation. Collaborations should include key partners from Latin American institutions, fostering meaningful partnerships to tackle significant health challenges faced by U.S. Hispanics/Latinos. The initiative highlights multiple application deadlines for standard and AIDS-related grants, promoting timely submissions for impactful research.

Youth Service America

Youth Service America believes that youth, communities, and our democracy thrive when we all work together for the common good. YSA is a leading global nonprofit that activates young people, ages 5-25, to find their voice, take action, and acquire powerful civic and 21st Century skills as they solve problems facing their communities. YSA supports its activation campaigns with grants, training and resources, and recognition programs for young people and their adult champions. Youth-led projects use Awareness, Service, Advocacy, and Philanthropy (ASAP) strategies to create social and environmental change.

Our vision is that youth participation in working together for the common good becomes the common expectation and common experience of all young people in America. Even though youth participation rates are at or near record-high levels, we’re still leaving 3 of every 4 young people out, and participation rates are even lower among youth from underserved low-income communities and communities of color.

We Serve to Remember 9/11 Day of Service Grants

YSA’s We Serve to Remember 9/11 Day of Service Grants are for organizations, schools, and youth changemakers ages 5-25 to lead service projects on or around September 11, 2026. Programming efforts should also honor and pay tribute to those who lost their lives on September 11, 2001, their families, and those who rose in service in response to that tragedy.

This year, YSA will award up to 100 grants of $1,000 each. Grantees are required to engage at least 100 youth as volunteers in planning and implementing the service activities.

Reflecting on the spirit of togetherness that brought people together in the days, weeks, and months after September 11th, we are especially looking for ideas that bring together all members of the community.

The State Trade Expansion Program (STEP) 2026, established by the Trade Facilitation and Trade Enforcement Act of 2015, aims to enhance export capabilities of eligible small businesses across the U.S. By providing federal grants to states, STEP supports projects designed to increase the number of small businesses that export, boost the dollar value of exports, and explore new trade opportunities. This program is crucial for fostering economic growth and enhancing global competitiveness.

The Eviction Protection Grant Program (EPGP) aims to support low-income tenants facing eviction by offering competitive awards to around 16 nonprofit organizations and government entities. These grants will fund no-cost legal assistance, covering pretrial, trial, post-trial, and alternative dispute resolution services. The initiative, backed by the Department of Housing and Urban Development, is designed to ensure that vulnerable tenants have access to essential legal resources, ultimately reducing eviction rates and promoting housing stability.

The CDC is offering FY 2027 funds for a cooperative agreement to enhance national surveillance for human prion diseases, or transmissible spongiform encephalopathies (TSEs), in the U.S. This initiative aims to confirm suspected cases and monitor emerging diseases through a specialized center utilizing advanced diagnostic techniques. Since 1997, this center has facilitated disease confirmation and trend evaluation, ensuring accurate surveillance and fostering confidence that novel prion diseases are not emerging in the country.

The CDC's NCIPC invites proposals for rigorous evaluations of programs aimed at preventing child sexual abuse (CSA) and problematic sexual behavior (PSB) among youth. This research aims to assess the effectiveness of prevention policies, especially in digital spaces and youth-serving organizations. Eligible proposals should address issues like online exploitation, harmful behaviors, and the impact of organizational policies on youth safety. This initiative seeks to enhance the evidence base for effective prevention strategies.

The HEAL Initiative aims to address the significant overlap between chronic pain (CP) and opioid use disorder (OUD), with 40-75% of individuals affected by both. The IMPOWR project focuses on testing innovative interventions and implementation strategies to integrate care for CP and OUD across various health systems. The BEACON Center will enhance network coordination, build capacity, and develop resources to address barriers in service delivery, ultimately improving sustainability and scalability of evidence-based practices.

The NIH Research Evaluation and Commercialization Hubs (REACH) program aims to facilitate the translation of biomedical discoveries into marketable products to enhance patient care. By funding five new academic entrepreneurship hubs, NIH will provide essential resources such as funding, mentorship, and expertise in product development. These hubs will address high-priority technologies and foster public-private partnerships, ultimately supporting the goals of federal research initiatives and addressing local health needs in underserved areas.

Rooted + Relational Community Micro-Grant Program

The Center for Puerto Rican Studies (CENTRO) at Hunter College has announced that it is now accepting applications for the 2026-2027 Rooted + Relational Community Micro-Grant program. CENTRO will award up to 12 grants, each up to $5,000, to non-institutionally affiliated and non-academic community organizations, individuals, or projects for community-based programs. 

The 2026-2027 the Rooted + Relational theme is Black Cuerpas: Race, Body Politics & Culture. CENTRO seeks to fund projects that examine

• How do race, gender, sexuality, and body politics shape the everyday lives and histories of Boricuas across the archipelago and diaspora? 
• What happens when we center race and Blackness in a field of study that has too often championed color-blindness and the myth of racial democracy to avoid the hard questions about racism, anti-Blackness, complicity, and erasure?

During the 2026-2027 academic year, grantees will implement their funded projects within their chosen communities. They will also present their work at a CENTRO event, attend three virtual meetings, and have their work highlighted through CENTRO’s communications and media channels. We invite community organizers, artists, creatives, writers, agricultural workers, activists, and cultural workers who reside in Puerto Rico and/or the United States and its territories to apply. 

The FY26 Neurofibromatosis Research Program's Exploration-Hypothesis Development Award encourages innovative, high-risk research concepts in neurofibromatosis (NF). This award aims to support groundbreaking studies that will pave the way for future scientific inquiries. Proposals should present a well-defined, testable hypothesis grounded in sound scientific rationale. While preliminary data is encouraged, it is not a prerequisite for submission, allowing researchers to explore novel paradigms and perspectives in NF research.

The PLTW Engineering grant, supported by the Arconic Foundation, aims to enhance STEM education by funding the implementation of PLTW Engineering courses in schools. This initiative prepares students for future careers by igniting their passion for engineering. Grants will cover startup costs for new programs or expansions of existing ones. Eligible schools must offer PLTW's Advanced Manufacturing course for the 2026-2027 school year, ensuring access to essential resources and training for educators.

The PLTW Engineering program, supported by Arconic Foundation, aims to expand STEM education in public and charter schools across several states. This grant will help cover costs for necessary equipment and training, focusing on high-need student populations. Eligible schools must implement PLTW's Advanced Manufacturing course by the 2026-2027 school year. The initiative is designed to ignite student interest in engineering and increase enrollment in STEM disciplines.

The NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01) invites applications to support clinical trials that require FDA oversight, aim to establish efficacy, or pose significant risks. This initiative, managed by the NIH, seeks to enhance interventions for communication disorders and encourages collaboration between NIDCD Project Scientists and investigators. Proposals are due by 5 PM local time, with Letters of Intent recommended 30 days prior to the deadline.

The Luce Indigenous Knowledge Fellowship, launched by the First Nations Development Institute and the Henry Luce Foundation, supports Native knowledge holders and makers in their transformative work. With ten fellowships of $75,000 each, this two-year program fosters growth and collaboration across diverse fields such as agriculture, climate change, and cultural revitalization. Fellows will engage in community-building through required convenings, enhancing their leadership skills and professional networks to benefit Native communities.

The FY26 Neurofibromatosis Research Academy – Scholar Award supports early-career independent investigators focusing on neurofibromatosis research. Scholars are required to be within 10 years of their terminal degree and must designate a Career Guide for mentorship, fostering collaboration. This initiative aims to advance impactful research and develop skilled researchers in a supportive environment, addressing critical areas of emphasis in neurofibromatosis research.

The Water & Waste Disposal Loan & Grant Program in Puerto Rico provides essential funding for rural communities to ensure access to clean drinking water, sanitary sewage disposal, and effective storm water drainage. Eligible applicants include state and local governments, nonprofits, and federally-recognized tribes. The funds can be utilized for construction, improvement, and financing of water systems, as well as related activities like legal fees and land acquisition, supporting sustainable community development.

The NEA Arts and Artifacts International Indemnity Program, established in 1975, supports the exhibition of significant art and artifacts by minimizing insurance costs for international exhibitions. Administered by the National Endowment for the Arts, it covers U.S. owned art during exhibitions in the country. The program evaluates applications through advisory panels and the Federal Council on the Arts and Humanities, ensuring that vital cultural works are accessible while providing necessary financial protections.

The Community Heart & Soul Seed Grant Program offers $10,000 in startup funding for community-driven groups in small towns to adopt the Community Heart & Soul model. Applications are accepted until 11:59 p.m. EST on the last business day of each month, with funding decisions made the following month. This initiative aims to empower residents to engage in local development and foster community connections.

The Can'd Aid: Crush It Crusade Grant empowers nonprofits, local education, and government organizations to enhance recycling efforts. With grants ranging from $3,000 to $8,000, the program supports initiatives that promote recycling at community events, engage volunteers, and foster inclusive outreach. Since 2014, over 125 organizations have benefited from this funding, driving impactful change through community engagement and environmental stewardship.

The Emergency Community Water Assistance Grants in Puerto Rico aim to assist eligible communities in preparing for or recovering from emergencies that threaten safe drinking water. Events qualifying as emergencies include droughts, floods, and chemical spills. The grants can be used for constructing water sources or repairing existing water distribution lines, with funding up to $1 million. This program is vital for ensuring access to clean water in rural areas following disasters.

The Libraries Transforming Communities: Accessible Small and Rural Libraries' Grant, initiated by the American Library Association (ALA), aims to enhance accessibility and community engagement in small and rural libraries serving people with disabilities. With funding up to $20,000, selected libraries will receive support for projects that improve library services and facilities. This initiative promotes collaboration with community members to identify and address accessibility needs, ensuring libraries effectively serve diverse populations.

The NEA Arts and Artifacts International Indemnity Program, administered by the National Endowment for the Arts, provides financial protection for museums exhibiting significant art and artifacts. Launched in 1975, it minimizes insurance costs for international exhibitions. The program allows U.S. entities to receive indemnity for works of art while on display in the U.S. Applications are assessed by expert panels, ensuring a thorough review process before approvals or conditional notices are issued.

The Community Seed Donations program by Seed Savers Exchange provides seeds to schools, community gardens, and nonprofits, ensuring that these resources are freely available to those in need. In addition, they offer disaster relief seed donations for organizations affected by recent natural disasters. To qualify, applicants must be nonprofits with U.S. shipping addresses. This initiative not only supports community growth but also promotes sustainability and resilience in the face of challenges.

This Request for Information (RFI) seeks input on the urgent need for gigawatt-scale electricity generation and transmission due to rapid demand growth from data centers and advanced manufacturing. The U.S. electric grid faces significant challenges, including limited capacity and aging infrastructure, which could hinder timely interconnection of new energy sources. Stakeholders are invited to provide feedback on overcoming regulatory and operational barriers to meet this escalating demand.