Best Puerto Rico Grants for Nonprofits

The Chronic Care Telehealth Centers of Excellence Program, funded by the Health Resources and Services Administration, aims to enhance chronic care management through innovative telehealth technologies. This initiative will support academic medical centers in integrating comprehensive telehealth services for chronic disease prevention, management, and acute episode treatment. The centers will also contribute to research publications, establishing national benchmarks for effective telehealth integration in chronic care.

The NIH Career Transition Award (K22) aims to support outstanding clinician-scientists in developing independent research skills. This grant facilitates a two-phase program, starting with an intramural appointment at the NIH followed by support at an extramural institution. Designed for NINDS intramural neurologist- and neurosurgeon-scientists, it helps them transition to independent academic faculty roles, enabling them to engage in funded scientific research alongside clinical activities.

The NCI CURE Mentored Clinical Scientist Research Career Development Award (K08) aims to support individuals with clinical doctoral degrees in developing research careers that address national health-related needs. This program focuses on enhancing the research capabilities of underrepresented clinical scientists in cancer research, including health disparities. Awardees receive protected time for supervised research training, preparing them to compete for future research project grants. Key deadlines for applications span from February 2025 to October 2027.

The NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required) grant invites applications for mid-phase clinical trials focusing on natural products such as botanicals and dietary supplements. It aims to advance scientific knowledge by determining optimal dosing and patient responses. Applicants must provide preliminary data demonstrating bioavailability and measurable impacts on target engagement. This initiative will not support efficacy trials for cancer treatments and encourages early contact with NCCIH scientific contacts.

The NCCIH Natural Product Early Phase Clinical Trial Award supports innovative clinical trials of natural products, such as botanicals and dietary supplements, with a strong scientific basis. Applications are encouraged to explore optimal delivery methods and combinations with other treatments. Funding is available for up to three years to assess the impact on target engagement and clinical outcomes, aiming to translate basic science findings into practical clinical applications.

The NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33) invites research proposals for early phase clinical trials of natural products, including botanicals and dietary supplements, emphasizing scientific validity for further testing. Applicants may receive up to three years of funding for pharmacokinetics and bioavailability studies, with potential for an additional three years to evaluate clinical outcomes. This initiative aims to optimize natural product delivery through innovative study designs.

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BlackRock Future Builders

BlackRock Future Builders is a $100 million philanthropic initiative funded by The BlackRock Foundation to expand economic opportunity and power the next generation of America’s skilled trades workers. Through this Request for Proposals (RFP) process, The Foundation seeks to support U.S. nonprofit organizations (i.e., registered 501(c)3 organizations) delivering or supporting high‑quality skilled trades training.

This competitive grant opportunity operates in parallel to other BlackRock Future Builders partnerships and is intended to surface additional, regionally grounded solutions across the skilled trades ecosystem. Organizations may propose direct worker training programs or capacity‑building efforts that enable systems to function more effectively and at greater scale. This first round RFP will be administered by Jobs for the Future (JFF), a national nonprofit that transforms U.S. education and workforce systems.

Focus Areas and Solutions

Applicants may propose worker training or capacity‑building solutions aligned to skilled trades workforce development.

• Worker training interventions may include direct service proposals such as pre-apprenticeship or career navigation programs, workforce training programs, apprenticeship programs, or wraparound participant supports that are supportive of training persistence and completion.
• Capacity-building interventions are organizational and system-focused, rather than in direct service of participants, and may include, but are not limited to, proposals such as ecosystem-building, demonstration projects, technology or tool adoptions, or research, among others.

The ACS-Hach Professional Development Grant provides up to $2,500 to support high school chemistry teachers in the U.S. as they pursue professional development opportunities. This grant aims to enhance teaching and learning in chemistry by funding activities such as conferences, workshops, and educational resources. It is designed to improve educators' skills and boost student achievement, thereby fostering a better learning environment in chemistry classrooms.

The Strategic Alliance Matching Grant - Division II offers financial support to enhance ethnic minority and gender representation in mid- to senior-level athletics administration roles across NCAA Division II institutions. With an annual budget of $860,000, the grant aims to fund up to 20 schools and conferences each year. Eligible applicants must be active Division II members and are encouraged to collaborate with their human resources departments during the proposal process, ensuring compliance with grant requirements.

The Integrated Viral Hepatitis Surveillance, Testing, Treatment, and Prevention Programs for Health Departments (IVH-STTP) aims to strengthen viral hepatitis surveillance and prevention efforts across the United States. By enhancing outbreak response capabilities and promoting testing and treatment in high-impact settings, this initiative seeks to improve public health outcomes. Key components include partnerships, strategic planning, and perinatal hepatitis C programs, ultimately striving for better access to prevention and treatment services, aligning with CDC priorities.

The National Centers for Biomedical Imaging and Bioengineering (NCBIB) provide critical resources for biomedical imaging and bioengineering research. This funding opportunity supports the development of innovative technologies tailored to the needs of basic, translational, and clinical researchers. NCBIB facilitates technology access, training, and dissemination, enhancing collaboration and advancing the field. Applications are encouraged to foster advancements that address complex biomedical challenges.

The FY26 Safer Outcomes Program, led by the U.S. Department of Justice's COPS, supports law enforcement agencies in enhancing crisis response training. This initiative aims to improve safety during police interactions through targeted training for officers, support staff, and mental health professionals. By providing crucial resources, the program fosters effective collaboration between law enforcement and mental health services, ensuring a comprehensive approach to crisis intervention and community safety.

The FY26 Community Policing Development (CPD) Accreditation Program aims to enhance law enforcement accreditation by supporting state, local, territorial, and Tribal agencies. Managed by the COPS Office, this initiative provides funding for technical assistance, accreditation cost support, and development of user-friendly policy templates. Applications must be submitted via JustGrants by September 3, 2026. This funding opportunity promotes community policing as a vital strategy for public safety.

The NCAA Graduate Student Research Grant Program offers funding up to $7,500 for graduate research focused on intercollegiate athletics and the psychosocial experiences of college student-athletes. It aims to enhance empirical research and provide financial support for high-quality projects. Eligible applicants must be enrolled in a graduate program at an NCAA member institution and engage in research during the award period. The program prioritizes studies that advance understanding in social and behavioral sciences.

The National Science Foundation (NSF) is funding initiatives to enhance the value of scientific datasets through innovative artificial intelligence (AI) methods. This program aims to facilitate interdisciplinary research and unlock new insights by applying AI for feature extraction, metadata generation, and dataset integration. Proposals should ensure data security and promote collaboration with various sectors to advance AI-driven scientific discovery. By aligning with NSF priorities, researchers can contribute to cutting-edge science and technology for broader participation in STEM.

The Ethnic Minorities and Women’s Internship Grant supports entry-level athletics administrative positions for one academic year, promoting diversity in NCAA Division II. It provides $30,000 for intern salaries and $3,000 for professional development, benefiting six schools annually from a total budget of $180,000. Eligible applicants must be active NCAA members, with a focus on enhancing ethnic minority and gender representation in athletics administration. This initiative encourages professional growth and compliance in diverse environments.

The Center for Inherited Disease Research (CIDR) provides high-throughput sequencing and genotyping services to support genetic research. It aims to identify genes linked to health and disease and enhance specimen classification through advanced genomic data. CIDR is a vital NIH initiative, offering cutting-edge platforms and statistical support that cannot be replicated in individual labs. For more information on their services, visit their website.

The NCAA Walter Byers Graduate Scholarship is awarded annually to one male and one female student-athlete, recognizing outstanding academic achievement and potential for success in graduate study. Each scholarship provides $24,000 for one academic year, with the possibility of renewal. Candidates must have a minimum GPA of 3.500, compete in NCAA athletics, and demonstrate strong character and leadership. The scholarship aims to support future leaders in their chosen fields, fostering excellence in academics and community engagement.

The NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) aims to support innovative research in behavioral and social interventions for dental, oral, and craniofacial conditions. This funding opportunity includes a milestone-driven planning phase of up to 2 years, with potential transition to implementation for an additional 5 years, facilitating comprehensive trial development and assessment.

The Academic Research Enhancement Award (AREA) supports small-scale research grants for institutions with limited NIH funding, emphasizing biomedical research experiences for undergraduates. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million in NIH support over the past seven years. This initiative aims to enhance the research environment at these institutions, fostering student involvement in research activities.

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) aims to support postdoctoral fellows from underrepresented backgrounds in transitioning to tenure-track positions. This award provides essential funding for salary and research support for three years, enabling candidates to establish independent biomedical careers. Key deadlines for applications range from February 2025 to October 2027, ensuring ample opportunity for eligible researchers to secure funding for their career development.

The NCI Continuing Umbrella of Research Experiences (CURE) Non-Mentored Research Scientist Career Development Award (K22) supports early-career independent researchers to transition from postdoctoral positions to assistant professor roles. This award aims to enhance diversity in the biomedical workforce, offering funding opportunities for innovative research projects. Key application deadlines span from February 2025 to October 2027. The program is funded by the US Department of Health & Human Services, specifically the National Institutes of Health (NIH).

The NIH Career Transition Award (K22) supports exceptional basic and clinical investigators in developing independent research skills through a two-phase program: an intramural appointment at NIH followed by support at an extramural institution. This award specifically aids NINDS intramural neurologist and neurosurgeon scientists in transitioning to independent academic faculty roles, fostering the engagement of clinician-scientists in both funded scientific research and clinical practices.

The Manufacturing Extension Partnership Center State Competition aims to support small and mid-sized manufacturers in the U.S. by facilitating the adoption of advanced manufacturing technologies. This initiative, funded by the NIST, encourages innovation in manufacturing through the integration of robotics, AI, and other technologies. Eligible applicants can establish MEP Centers in various states, helping manufacturers improve competitiveness and economic outcomes. This program is vital for enhancing productivity and fostering growth in the manufacturing sector.

The NIJ FY 2026 Research and Evaluation of Services for Victims of Crime funding opportunity aims to enhance support for crime victims and survivors. This initiative, a collaboration between the National Institute of Justice and the Office for Victims of Crime, will fund projects in two categories: research on law enforcement-based victim services and studies addressing technology-facilitated abuse. Applications are due by August 21, 2026, to improve victim assistance initiatives.