Best Greenville County Grants for Nonprofits in South Carolina

The OREF/ASES Rockwood Clinical Shoulder Research Grant aims to foster innovative clinical research in shoulder care. By offering seed funding to new investigators, this grant supports promising projects that demonstrate clinical relevance and practical application. Successful completion will position principal investigators to pursue larger NIH or DOD funding opportunities, further advancing shoulder research. This initiative underscores the commitment to nurturing talent and excellence within the field.

The OREF Multimodal Musculoskeletal Perioperative Pain Management Grant invites research proposals aimed at enhancing perioperative pain management strategies. This funding opportunity emphasizes opioid-sparing techniques and effective regional anesthesia methods to improve patient outcomes in orthopedic surgeries. Eligible applicants include Certified Registered Nurse Anesthetists (CRNAs) in collaboration with PhDs or MDs, fostering a diverse range of expertise in pain management research.

The SC Arts Commission offers Accessibility Grants to assist organizations in making arts programs and facilities accessible to individuals with disabilities. Funded projects may include adaptations such as Braille materials, sign language interpretation, and facility modifications. Eligible applicants include government units and charitable organizations registered in South Carolina. The program emphasizes cash matching and limits awards to one per fiscal year, prioritizing projects in designated Opportunity Initiative Counties.

The S.C. Arts Commission's Folklife & Traditional Arts Project Grants support non-profit organizations and government units in preserving and promoting South Carolina's traditional arts. This program aims to keep living cultural traditions vibrant through various projects, including workshops, festivals, and documentation efforts. Eligible applicants must be non-profit organizations with a valid DUNS number or government units. The grant encourages community engagement and the celebration of cultural heritage across the state.

The General Operating Support (GOS) Grants offer three years of unrestricted funding to arts organizations in South Carolina. These grants aim to strengthen organizations that provide ongoing arts experiences and services. Eligible applicants include various arts organizations focused on producing, presenting, or education. Funding is contingent upon factors like panel review and the size of the applicant's budget, with awards varying annually based on available funds.

The SCAC Individual Artist Fellowships aim to honor the artistic accomplishments of South Carolina's individual artists. With awards of $10,000, these fellowships are competitive and based on artistic merit, achievements, and dedication to the discipline. Eligible applicants must be legal residents of South Carolina, over 18 years old, and not degree-seeking students during the award period. Up to five fellowships are awarded annually, with specific artistic disciplines rotating each year.

The Arts Project Support Grants by the South Carolina Arts Commission aim to fund quality arts projects and programs for artists and organizations. Eligible applicants include artists, nonprofit organizations, and government units, with funds supporting project costs such as technical capacity building and professional development. Priority is given to projects in specific counties within South Carolina. Applications should be submitted at least five weeks prior to project commencement, with all activities funded to occur between August 11, 2025, and May 31, 2026.

The SCAC Term Arts Education Project Grants support quality arts education for preschool and K-12 students during the 2025-2026 academic year. The grants aim to enhance access to arts education, integrate arts with school curricula, and address South Carolina’s educational standards. Eligible applicants include colleges, local governments, and nonprofit organizations. Priority is given to projects serving underserved communities and addressing learning loss caused by COVID-19, ensuring a broad impact on students' educational development.

The Professional Development and Artistic Planning Grants, offered by South Arts, support the professional growth of presenters, programmers, and curators in the Southern U.S. These grants facilitate travel to conferences, workshops, and other opportunities to enhance organizational capacity and program design. Emphasizing diversity and inclusion, South Arts encourages applications from organizations led by BIPOC, LGBTQIA+, and disabled individuals. Funding covers travel, training, and related expenses, promoting equitable access to professional development.

The Lotte Lenya Competition, established in 1998 by the Kurt Weill Foundation for Music, honors the legacy of renowned actress Lotte Lenya. This unique contest blends acting and vocal skills, targeting performers aged 19-32 from diverse backgrounds. Celebrating its 25th anniversary in 2023, the competition has increased its prize offerings, with over $1.6 million awarded to more than 800 singers. It's a prestigious platform that has propelled many winners to successful careers in musical theater and opera.

The See, Test & Treat Grant offers funding for a pathologist-led cancer screening program aimed at underserved communities. With a focus on health education, the program provides vital cervical and breast cancer screenings, ensuring same-day results and follow-up care. Eligible institutions can apply for funding up to $20,000 for single-year projects or up to $50,000 over three years. This initiative addresses health disparities, empowers communities, and enhances the visibility of pathology in healthcare.

The First Book Grant for Scholars of Color (FBG) offers up to $55,000 to support early-career, pre-tenured scholars of color in completing significant research projects related to Christian faith and life, religious trends, and social issues. This grant aims to facilitate the publication of their first book, enhancing the connection between academic scholarship and the church in North America, while prioritizing projects that are already underway.

The Japanese Teaching Material Purchase Grant, provided by the Japan Foundation, Los Angeles, supports U.S. educational institutions in acquiring resources for Japanese language courses. Grants, not exceeding $1,000, can be used for textbooks, audio-visual aids, and other teaching materials. Eligible applicants include non-profit organizations and Japanese heritage schools. However, the grant does not cover electronics or consumable supplies, and materials purchased become institutional property, not personal.

The Salary Assistance Grant for Japanese-Language Courses, administered by the Japan Foundation, Los Angeles, supports U.S. non-profit educational institutions and Japanese heritage language schools facing financial difficulties. Grants cover a portion of the salary and benefits of Japanese language instructors, up to $30,000 per year. Institutions can apply for one or two years of funding, with priority given to new programs and the maintenance of existing programs. Applications must detail cost-sharing plans.

The Japanese-Language Education Project Grant supports initiatives that enhance Japanese language education across various regions. Offered by the Japan Foundation, Los Angeles, this grant targets workshops, seminars, and original projects that connect language learning with Japan Studies. Eligible applicants include non-profit educational organizations in the U.S. Projects should benefit multiple programs, ensuring a broad impact on Japanese language education. The deadline for applications is two months before the project start date, which must be between April 1, 2025, and March 31, 2026.

Since 2002, the ACA has partnered with L.L. Bean to sponsor the Club Fostered Stewardship (CFS) Program. The CFS Program provides funding to local and regional paddling clubs and organizations that undertake stewardship projects on waterways in their area. The purpose of the program is to encourage paddling clubs to take an active role in protecting and improving the nation's waterways. 

Many of the stewardship needs of our nation's waters are best addressed at the local and regional level. Paddling clubs and watershed organizations are in an ideal position to lead these efforts. These paddlers are often willing to volunteer their time and assist with local stewardship projects. However, clubs often lack the funds needed to pay project expenses. As a result, they miss an opportunity to leverage dozens and sometimes hundreds of volunteer hours that could improve conditions on their favorite waterway.

CFS Grant Program

That is why L.L. Bean and the ACA have teamed up to sponsor the CFS Program.

CFS grants are available for projects that utilize volunteers in efforts to protect, maintain or restore recreational waterways, to provide for or improve public access, or to enhance safe navigation. 

Grant amounts range from $100-$1,000.

Past projects receiving CFS grants include:

• Removing heavy debris and trash from rivers and bays in numerous locations throughout the U.S.
• Improving access for local paddlers
• Establishing water trails 
• Water quality monitoring 
• Environmentally-sensitive woody debris removal 
• Riparian buffer restoration and improvement 
• Environmental education and outreach programs

ACA also offers additional assistance to clubs and organizations for waterway stewardship projects. Clubs and organizations concerned about liability for injuries that occur during stewardship projects may be able to obtain liability insurance coverage through the ACA. Clubs may request additional assistance using the It is not mandatory to be a paddling club to apply. In the past, grants have been awarded to conservation organizations and watershed groups.

Want to learn more about projects that have been funded through the CFS program? Review reports from past years!

DICK'S Sporting Goods offers a Sponsorships & Donations Program aimed at supporting youth sports leagues and organizations. They prioritize requests that promote community engagement and character development through sports. Eligible organizations must operate in areas with a DICK'S store and adhere to anti-discrimination policies. The program evaluates requests monthly, with sponsorships up to $25,000 and donations up to $250. Support may include gift certificates or coupons for teams and events, fostering an inclusive sports culture.

The Learning & Leadership Grants support educators in enhancing their professional development and leadership skills. With funding up to $5,000, these grants are available for individual educators or groups pursuing high-quality learning experiences such as conferences and seminars. Eligible applicants must be current members of the National Education Association. These grants aim to empower educators to implement innovative practices in their classrooms, ultimately benefiting students and the educational community.

The Combined Pilot Research Grants by the Plastic Surgery Foundation and the American Association for Hand Surgery aim to promote innovative research in hand surgery and related fields. Grants of up to $15,000 are available for one-year pilot projects to help develop surgeon scientists and advance clinical practices. Applicants must be affiliated with U.S. or Canadian institutions and hold relevant qualifications. The initiative emphasizes funding projects that contribute to the scientific knowledge of hand surgery.

The PSF Research Fellowships aim to support early-career investigators in plastic surgery by providing salary support for residents or fellows to gain research training and experience. Applicants must present a structured research training plan and project, focusing on already funded research. Grants of up to $50,000 are available for one year, emphasizing the training experience, project quality, and mentor commitment.

The Warren MacKenzie Advancement Award supports students and emerging ceramic artists in the U.S. to enhance their skills and knowledge through research and education for up to twelve months. Eligible applicants include current students and recent graduates in ceramics. The award offers a maximum of $2,000 for travel, education, or research, enabling recipients to explore new techniques, collaborate with mentors, and attend workshops, thereby fostering professional growth in the field of ceramics.

The Diversity Mentorship Grant Program aims to enhance ethnic diversity in dermatology by providing mentorship to underrepresented medical students. Participants receive 160 hours of hands-on experience with a dermatologist, fostering a deeper understanding of the field. A stipend of $1,500 is available for travel and living expenses. Applications are open until November 1 for the upcoming year, encouraging students from diverse backgrounds, including Black, Hispanic, and Native American groups, to apply.

The Southern Partners Fund's Discretionary Fund Grant aims to support grassroots community organizing for social, economic, and environmental justice in the Southeastern United States. It provides financial resources and technical assistance to rural organizations and leaders focused on transformative change. Eligible applicants include self-governed rural groups engaging in advocacy and community development. The fund prioritizes education reform, immigration rights, and voter engagement, allowing up to two requests per year, with a maximum award of $3,500.

The Hubert E. Sapp Regular Grant Cycle, by Southern Partners Fund, aims to empower rural communities in the Southeastern U.S. through grassroots leadership and organizing. The fund provides support to nonprofit organizations focused on social, economic, and environmental justice. Eligible applicants are community-based organizations with budgets under $350,000. The initiative honors Hubert E. Sapp's legacy, promoting equitable relationships that drive real transformation and community decision-making.

The AABCF Research Grants, offered by the American Association of Birth Centers Foundation, provide funding up to $5,000 for research projects focused on the birth center model of care. Open to individuals and organizations, these grants aim to enhance knowledge and practices in maternity and women's health care. Projects must demonstrate a clear plan and ability to complete the research on schedule, ensuring impactful contributions to the field.

The Changemaker Accreditation Grants support birth centers in achieving and maintaining accreditation by covering up to 100% of the initial or annual fees required by the Commission for the Accreditation of Birth Centers. This initiative honors the pioneers of the birth center movement and aims to assist centers that demonstrate financial hardship and a commitment to serving low-income communities. Special consideration is given to those fostering public education and located in rural areas.

The Birth Center Membership Support Grants, offered by the American Association of Birth Centers Foundation, aim to assist birth centers facing financial hardships in paying membership fees. Eligible centers can receive support covering up to 50% of the fees, whether they are applying for membership for the first time or renewing their membership. This initiative emphasizes the importance of maintaining high standards in maternity care and supports centers committed to serving low-income women.