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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,483 Results based on applied filters

Mallove Family-William Pedace Scholarship

Community Foundation of Eastern Connecticut
Private
United States
Unspecified amount
The Mallove Family-William Pedace Scholarship, established by the Community Foundation of Eastern Connecticut, offers $750 to support New London High School students with strong academic abilities. Since 1983, the foundation has awarded over $11.9 million in scholarships, helping students pursue their educational goals and build successful careers. This scholarship is designed to assist deserving individuals in achieving their dreams by providing financial aid for college expenses.
Academic Scholarship Programs

HuFriedyGroup/Esther Wilkins Instrument Scholarships

American Dental Hygienists’ Association (ADHA)
Private
United States
Approximately US $1,000
The HuFriedyGroup/Esther Wilkins Instrument Scholarships, sponsored by the American Dental Hygienists’ Association (ADHA), support students enrolled in accredited dental hygiene programs in the U.S. This scholarship provides recipients with up to $1,000 worth of dental hygiene instruments of their choice. Eligible applicants must maintain a minimum GPA of 3.0 and be ADHA members. This initiative seeks to enhance educational opportunities and promote professional growth among future dental hygienists.
Dental Health

Deeper Learning Implementation Grant

Massachusetts Department of Elementary and Secondary Education
State/Local Government
Massachusetts
Up to US $16,000
The Deeper Learning Implementation Grant, offered by the Massachusetts Department of Elementary and Secondary Education, aims to enhance educational outcomes for underserved students through targeted funding and support. It encourages schools to engage in collaborative practices and professional development, fostering deeper learning. Eligible public and charter schools can apply for stipends to support instructional priorities and improve leadership systems. This initiative focuses on achieving sustainable changes in teaching methodologies and enhancing student engagement through innovative learning strategies.
Academic Success & Enrichment

American Urological Association: Research Scholar Award

American Urological Association Inc
Private
Canada, Central America +2 more
Up to US $80,000
The American Urological Association's Research Scholar Award offers $40,000 annually for one or two years of mentored research training. This program aims to attract promising young investigators into urologic research, providing essential support to clinical and postdoctoral fellows within five years of completing their doctorate or residency and early career faculty within their first five years. This funding opportunity is crucial for fostering the next generation of urologic researchers.
Urology

Regional Everyone Outdoors Grant Program

Community Foundation of the Ozarks Inc.
Private
Barry County, Missouri, Barton County, Missouri +61 more
Up to US $10,000
The Regional Everyone Outdoors Grant Program, offered by the Community Foundation of the Ozarks, aims to enhance community engagement with the natural resources of the Ozarks. Nonprofit organizations, government entities, and schools in rural Missouri are invited to apply for funding to support innovative outdoor programming. Ideal projects focus on low-income neighborhoods and include environmental education, equipment purchase, and community gathering space enhancement. This grant does not require matching funds, promoting broader participation in outdoor activities.
Environmental Education Outdoor Equity

Northwest Grain Growers Robert Abbey Memorial Scholarship

Blue Mountain Community Foundation
Private
Idaho, Oregon +1 more
Unspecified amount
The Northwest Grain Growers Robert Abbey Memorial Scholarship, established by the Blue Mountain Community Foundation, supports graduating seniors from high schools within the NWGG service area. This scholarship is available to members, employees, and their children, fostering educational opportunities and community development. Since its inception in 1984, the foundation has played a crucial role in enhancing the region's charitable landscape, managing over $115 million in assets across more than 440 funds.
Academic Scholarship Programs

St. Marys Methodist Church Foundation Grant

St Marys United Methodist Church Foundation Inc
Private
Brantley County, Georgia, Camden County, Georgia +2 more
Unspecified amount
The St. Marys Methodist Church Foundation Grant supports nonprofit organizations that provide essential services to those in need. Established in 2001, the Foundation prioritizes initiatives that promote well-being, health, education, and community engagement. It encourages collaborative projects that demonstrate measurable impact and long-term sustainability, ensuring that funds are used effectively to enhance the lives of individuals in Southeast Georgia and beyond. The Foundation aims to facilitate meaningful change through its grants.
Christianity Nonprofit Growth & Development

Aldo DeDominicis Scholarship Fund

Greater Hartford Gives Foundation
Private
Connecticut
US $1,500 - US $2,000
The Aldo DeDominicis Scholarship Fund supports students who have received a Farmington UNICO scholarship, promoting educational opportunities for those who have demonstrated financial need and maintained a "B" average. Established in honor of Aldo DeDominicis, an immigrant who built a successful media career, the fund reflects his belief in sharing wealth to foster community growth. This initiative aims to empower young scholars in the Greater Hartford area, encouraging them to achieve their academic goals and contribute positively to society.
Education - Higher Education

JLB Academic Scholarship

Junior League Of Birmingham Inc
Private
Jefferson County, Alabama, Shelby County, Alabama
US $1,000 - US $2,500
The JLB Academic Scholarship, provided by the Junior League of Birmingham, supports women in their pursuit of higher education. Established in 2012, this annual non-renewable scholarship awards between $1,000 and $2,500 to deserving candidates based on financial need and leadership potential. Eligibility includes residency in Jefferson or Shelby County, a minimum GPA of 3.0, and active community involvement. The scholarship fosters the development of future leaders in Birmingham, emphasizing the importance of women’s leadership.
Education - Higher Education

American Urological Association Rising Stars in Urology Research Award

American Urological Association Inc
Private
Canada, Central America +2 more
Unspecified amount
The American Urological Association Rising Stars in Urology Research Award supports physician-scientists in their journey to become independent researchers in urology. By providing supplemental salary support for up to five years, the program ensures awardees maintain protected research time while receiving competitive compensation. This initiative encourages promising researchers to compete for further funding and enhances their training in urologic research, ultimately advancing the field and improving patient care.
Urology

AUA Data Research Grant Program

American Urological Association Inc
Private
Canada, Central America +2 more
Approximately US $2,000
The AUA Data Research Grant Program, funded by the American Urological Association Inc, aims to enhance urologic research by fostering a diverse group of dedicated professionals. This initiative focuses on bridging knowledge gaps in urology care and cultivating physician scientists through access to comprehensive data sources and mentorship from AUA Data Committee experts. By supporting innovative research, the program contributes significantly to the advancement of patient care in urology.
Urology

Urology Care Foundation International Student Humanitarian Grant- Trinidad and Tobago

Urology Care Foundation Inc
Private
Trinidad and Tobago
US $4,000
The Urology Care Foundation International Student Humanitarian Grant supports a medical student to undertake humanitarian work in Trinidad and Tobago. This grant is aimed at AUA Medical Student members, focusing on improving public health and urologic care for this underserved population. The project lasts 6-8 weeks during the summer, typically between the first and second years of medical school, encouraging diversity among applicants from accredited medical schools.
Urology

2025-2026 Board of Managers Support

Texas Education Agency
State/Local Government
Texas
US $200,000
The Texas Education Agency is initiating the 2025-2026 Board of Managers Support project to enhance educational governance. This initiative will provide vital training, observational interviews, and capacity-building resources for prospective Board of Managers. By collaborating with the Director of Governance Interventions, the selected applicant will ensure that all activities align with established standards, fostering sustainable systems for improved educational outcomes in Texas.
Academic Success & Enrichment

UMN Graduate School: Co-Sponsorship Grants

University of Minnesota
Private
Minnesota
Up to US $2,000
The University of Minnesota's Co-Sponsorship Grants Program offers funding up to $2,000 to support events that enhance training for graduate students and postdoctoral scholars. Eligible activities must align with the Graduate School's mission and be accessible to students across various colleges. Preference is given to initiatives demonstrating potential for sustainable impact. Applications are accepted on a rolling basis until funds are exhausted, so timely submission is crucial for consideration.
Education - Higher Education

OMYF Micro Grants

Orlando Magic Youth Foundation Inc
Private
Brevard County, Florida, Lake County, Florida +5 more
Up to US $10,000
The OMYF Micro Grants program, initiated by the Orlando Magic Youth Foundation, aims to support small organizations dedicated to enhancing the lives of youth in Central Florida. By providing grants of up to $10,000, the program focuses on grassroots initiatives in areas such as arts, education, health & wellness, and homelessness. This funding is essential for organizations with operational budgets under $500,000, allowing them to bring their impactful projects to life.
Youth Services

Bud and Linda Tarrson Fellowship

American Academy of Periodontology
Association/Society
United States
US $30,000
The Bud and Linda Tarrson Fellowship, awarded by the American Academy of Periodontology Foundation, offers $30,000 ($10,000 annually for up to three years) to periodontists aiming for academic careers. Eligibility includes being a faculty member at an instructor or assistant level and having no more than ten years of affiliation with a degree-granting institution. The fellowship supports research and teaching in periodontology, enhancing educational opportunities in the field.
Dental Health

Nunes Family Scholarship

Community Foundation of Eastern Connecticut
Private
New London County, Connecticut
Approximately US $500
The Nunes Family Scholarship, established by the Community Foundation of Eastern Connecticut, provides $500 to students from Southeastern Connecticut or Westerly, RI attending Mitchell College. Since 1983, the foundation has awarded over $11.9 million in scholarships to support local students in pursuing higher education and achieving successful careers. Scholarship funds are disbursed to colleges by August 1, ensuring timely support for students' educational needs.
Academic Scholarship Programs

Underprivileged Children Fund

Nemaha County STEP Foundation
Private
Nemaha County, Kansas
Unspecified amount
The Underprivileged Children Fund, managed by the Nemaha County STEP Foundation, aims to support local non-profits in Nemaha County that assist children in need. This fund focuses on families earning less than $50,000 annually, covering essential needs such as medical care, food, and clothing for children up to age 18. Grant recipients are required to provide detailed reports on fund usage and demonstrate the project's impact through stories and evidence.
Youth Services

NCC Foundation: Path2Succes Scholarship

Norwalk Community College (NCC) Foundation
Association/Society
Connecticut
Unspecified amount
The NCC Foundation's Path2Success Scholarship supports Fairfield County residents pursuing degrees or certificates at CT State Norwalk, excluding nursing students. Eligible candidates must maintain a GPA between 2.0 and 3.2, complete between 12-30 credits (Spring) or up to 64 credits (Academic Year), and enroll in at least 6 credits per semester. Applicants must also submit the FAFSA or relevant documentation, ensuring access to educational opportunities that foster student success.
Education - Higher Education

NCC Foundation: Spring Semester Scholarship

Norwalk Community College (NCC) Foundation
Association/Society
Connecticut
Unspecified amount
The NCC Foundation offers the Spring Semester Scholarship to support Fairfield County residents enrolled in degree or credit certificate programs at CT State Norwalk. This scholarship provides tuition assistance for the Spring semester, and eligible students must maintain a minimum GPA of 2.80 and complete at least 12 credits by the end of the fall semester. This initiative aims to enhance access to quality higher education and foster student success.
Education - Higher Education

Albert C. and Rose Turri Scholarship

Northwest Connecticut Community Foundation
Private
United States
US $1,000
The Albert C. and Rose Turri Scholarship, offered by the Northwest Connecticut Community Foundation, supports students pursuing a degree in electronics or electrical engineering. Established in memory of Albert and Rose Turri, this scholarship awards two $1,000 grants to eligible students residing in NCCF's service area. It aims to empower local talents to achieve their educational goals while championing community causes through dedicated support.
Academic Scholarship Programs

Helen and Mario Garbin Scholarship

Northwest Connecticut Community Foundation
Private
United States
Approximately US $500
The Helen and Mario Garbin Scholarship, offered by the Northwest Connecticut Community Foundation, supports students from NCCF's 20-town service area pursuing undergraduate or graduate studies. With an average award of $500, this scholarship reflects a commitment to fostering education and community engagement. The foundation emphasizes attentive grant-making and collaboration to address local needs, ensuring that donors and organizations effectively work together for impactful results.
Academic Scholarship Programs

American Veterinary Medical Foundation (AVMF) Veterinary Pharmacology Fellowship Grant

American Veterinary Medical Foundation
Private
United States
Up to US $10,000
The American Veterinary Medical Foundation (AVMF) Veterinary Pharmacology Fellowship Grant supports graduate students pursuing careers in veterinary pharmacology research. Funded in collaboration with the Veterinary Pharmacology Research Foundation, this grant offers up to $10,000 for a one-year fellowship. It covers expenses related to training, professional travel, stipends, and scholarly activities, aiming to enhance the number and quality of skilled researchers in the field.
Veterinary Science & Services

Sharon Orloski Scholarship

The Community Foundation of Greater New Britain
Private
Connecticut
US $500 - US $30,000
The Sharon Orloski Scholarship, offered by the Community Foundation of Greater New Britain, supports students at Central Connecticut State University pursuing degrees in life sciences. This scholarship particularly favors women demonstrating commitment and potential in scientific fields, aiming to enhance academic achievement and promote women's representation in the life sciences. With a focus on fostering future leaders, it reflects the Foundation's mission to inspire philanthropy and address community challenges through education.
Education - Higher Education

American Urological Association: Medical Student Fellowships

American Urological Association Inc
Private
Canada, Central America +2 more
US $4,000
The American Urological Association offers Medical Student Fellowships to enhance urological research. This program allows exceptional medical students to engage in mentored research with leading urologic scientists, receiving a stipend of $4,000. The initiative aims to cultivate the next generation of urologic researchers. Importantly, research projects no longer require a full 10-week commitment during summer, providing greater flexibility for participants. This fellowship is a significant opportunity for young investigators to contribute to advancements in urological care.
Urology

UMN Graduate School: Professional Development Funding Request

University of Minnesota
Private
Minnesota
Up to US $500
The UMN Graduate School offers Professional Development Funding to support graduate students engaged in opportunities that enhance their academic pursuits. Eligible activities include attending workshops, conferences, or learning new techniques. Funding amounts vary based on travel distance, with a maximum of $500 available. Applicants must be enrolled in research-based graduate programs and in good standing. This funding is available from September 1, 2025, to August 31, 2026, with applications accepted monthly.
Education - Higher Education

Portland Arts Project Grant Program

Regional Arts & Culture Council
Private
Clackamas County, Oregon, Columbia County, Oregon +3 more
US $1,000 - US $10,000
The Portland Arts Project Grant Program, administered by the Regional Arts & Culture Council, aims to enhance artistic development and community engagement in Portland, Oregon. This program supports individual artists and organizations with funding ranging from $1,000 to $5,000 for projects that foster public participation in the arts. Eligible applicants must reside or operate within Portland city limits. The program prioritizes investment in under-represented communities, ensuring equitable access to the arts.
Arts / Culture Access & Participation

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.