Upcoming Webinar
How Funders Feel About AI, and What Keeps Them Saying Yes.
Wed, Oct 14 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

32,483 Results based on applied filters

Hearst Endowment for Native American Studies Scholarship

Montana State University
State/Local Government
Montana
Unspecified amount
The Hearst Endowment for Native American Studies Scholarship at Montana State University supports students pursuing degrees in Native American Studies. This scholarship is specifically for American Indian or Alaska Native students, reflecting the university's commitment to inclusivity and educational access. With a rich history dating back to 1893, MSU continues to provide transformative higher education opportunities. The scholarship aims to empower and uplift Native American communities through education.
Education - Higher Education

Site-Based Clinical Training Grant Program

Minnesota Department of Health
State/Local Government
Anoka County, Minnesota, Carver County, Minnesota +5 more
Unspecified amount
The Site-Based Clinical Training Grant Program, administered by the Minnesota Department of Health, aims to enhance clinical healthcare training throughout Minnesota. With a funding estimate of $4,657,000 for FY 2026, this grant prioritizes rural primary care and oral health training. Eligible applicants include clinical training sites actively enrolled in the Minnesota Health Care Program, which must demonstrate their commitment to addressing healthcare shortages in underserved areas. This initiative supports the development of a skilled healthcare workforce.
Medical Education & Professional Training

David Center for the American Revolution Short-Term Resident Research Fellowships

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $3,000
The David Center for the American Revolution at the American Philosophical Society offers short-term resident research fellowships for scholars focused on the American Revolution and Founding Era. Awarded fellows receive a stipend of $3,000 for a one-month residency, enabling them to utilize extensive collections, including manuscripts and microfilms. Open to Ph.D. holders and candidates, these fellowships are available from June 1, 2026, to May 31, 2027, promoting research that contributes to the understanding of early American history.
American History

Centers of Research Excellence in Science and Technology

National Science Foundation (NSF)
Federal Government
United States
Unspecified amount
The Centers of Research Excellence in Science and Technology (CREST) program, funded by the National Science Foundation, aims to strengthen research capabilities at Minority-serving institutions (MSIs). It encourages the integration of STEM research and education, promoting diversity within the workforce. Successful proposals are expected to demonstrate innovative strategies for broadening participation and achieving national competitiveness in research. CREST Centers will also foster partnerships that advance significant research themes, ensuring sustained support and development for underrepresented groups in STEM.
STEM / STEAM Education

Amateur Sporting Tax Credit Grant Program

Missouri Department of Economic Development
State/Local Government
Missouri
Unspecified amount in in-kind support
The Amateur Sporting Tax Credit Grant Program incentivizes local community organizations to host amateur sporting events by providing tax credits. These credits can amount to $5 per ticket sold, $10 per paid participant, or 100% of eligible costs. With a funding cap of $3 million annually, events in certain counties are limited to $2.7 million. This program is administered through a structured application process involving proposal submissions and notifications.
Sports & Athletics

RWA Perseverance Fund

ROMANCE WRITERS OF AMERICA INCORPORATED
Private
United States
US $99
The RWA Perseverance Fund, administered by the Romance Writers of America (RWA), supports members in financial need for their annual national dues. RWA, a nonprofit organization, is dedicated to advancing the interests of romance writers through advocacy and networking. The fund is available to applicants who can demonstrate financial need and commitment to a career in romance writing. Eligibility includes submitting proof of work, while ensuring a respectful and inclusive environment for all members.
Writing & Literature

Consolidated Victim Services RFA

District of Columbia Office of Victim Services and Justice Grants (OVSJG)
State/Local Government
District of Columbia
Unspecified amount
The Consolidated Victim Services RFA provides funding to enhance a comprehensive network of trauma-informed services for crime victims in the District of Columbia. It addresses domestic violence, stalking, and sexual assault while promoting victim safety and offender accountability. Eligible applicants include community-based non-profits and for-profits without profit in their application. Funding sources include VOCA, VAWA, and SASP grants, supporting recovery and navigation through justice processes.
Crime Victim Services

Community Outreach Grants

The Children's Trust
Private
Miami-Dade County, Florida
Up to US $10,000
The Community Outreach Grants by The Children's Trust aim to empower community partners by supporting programs that benefit children and families in Miami-Dade County. These grants typically offer funding under $10,000 for events that connect families with essential resources and learning opportunities, aligning with the organization's strategic framework. This initiative fosters partnerships and outreach efforts to enhance community engagement and support.
Family Services

Women’s Fund of Door County Community Grants

Door County Community Foundation
Private
Door County, Wisconsin
Approximately US $5,000
The Women’s Fund of Door County Community Grants support initiatives that empower women and girls through education, self-esteem building, and addressing critical issues with research-based solutions. Charities serving this demographic in Door County are encouraged to apply, especially those focusing on inclusivity and innovative approaches. With no set grant limits, the program typically awards around $5,000 per grant cycle, promoting lasting impacts within the community.
Women & Girl Services

David Center for the American Revolution Postdoctoral Fellowship

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $30,000
The David Center for the American Revolution offers a nine-month residential postdoctoral fellowship for graduate students focusing on the American Revolution and Founding Era (1750-1800). This fellowship, based at the American Philosophical Society Library & Museum, is designed for advanced Ph.D. candidates nearing dissertation completion. A stipend of $50,000 per year for two years is available. The fellowship emphasizes the importance of utilizing the extensive collections at the APS and encourages applicants from both U.S. and foreign backgrounds.
American History

NAPB Borlaug Undergraduate Scholars

National Association of Plant Breeders (NAPB)
Association/Society
United States
Unspecified amount
The NAPB Borlaug Undergraduate Scholars program, established by the National Association of Plant Breeders, aims to cultivate future leaders in plant breeding. Open to undergraduates in relevant disciplines, the program provides mentorship opportunities and financial support for travel to the NAPB Annual Meeting. Those eligible must be current undergraduates and may not have received similar scholarships previously. This initiative fosters professional development and engagement in the field of plant improvement.
Plant Science

Dog Enrichment Grant

Petfinder Foundation
Private
Canada, Mexico +1 more
Up to US $4,000
The Dog Enrichment Grant, offered by the Petfinder Foundation, aims to enhance the quality of life for dogs awaiting adoption through enrichment activities and items. Grants are available for play yard renovations (up to $3,000) and interactive items (up to $1,000). Applications are accepted monthly until funds are depleted, and the window closes on November 1. Eligible expenses must be utilized within three months, and reimbursement requests will not be accepted.
Animal Welfare - Domestic Animals & Pets

RFP: Teacher Training Projects for Accredited or Nearly Accredited Preschools in Hawaii

Samuel N & Mary Castle Foundation
Private
Hawaii
Up to US $25,000
The Samuel N. and Mary Castle Foundation invites proposals for teacher training projects aimed at accredited or nearly accredited preschools in Hawaii. With grants up to $25,000, the Foundation supports initiatives that enhance teacher quality and retention, ensuring educators receive the necessary training. Eligible preschools must demonstrate commitment to faculty development and provide evidence of tax-exempt status. This initiative addresses the growing demand for well-trained preschool educators, ultimately benefiting children's educational outcomes.
Teacher Development & Training

Learning Event Support: Community-Led Grants

Advancing a Healthier Wisconsin Endowment
State/Local Government
Wisconsin
Up to US $5,000
The Advancing a Healthier Wisconsin Endowment offers Community-Led Grants to support Wisconsin-based learning events aimed at enhancing the skills and networks of health workforce professionals. With a total funding of $100,000 available, eligible organizations can apply for up to $5,000 to cover event-specific expenses. This initiative emphasizes addressing learning gaps and fostering health equity, ensuring impactful contributions to community health outcomes.
Medical Education & Professional Training

Youth as Resources Grants

Door County Community Foundation
Private
Door County, Wisconsin
US $200 - US $500
The Youth as Resources Grants provide financial support to youth-led projects that aim to serve or educate the community in Door County. Grants typically range from $200 to $500, with exceptional projects potentially receiving more. Any youth group primarily composed of Door County residents is eligible to apply, fostering engagement and development of youth skills while benefiting the local area.
Youth Services

Wilford Kallmeyer Emergency Responders Grantmaking Program

Community Foundation of the Ozarks Inc.
Private
Gasconade County, Missouri
Up to US $1,032

Wilford Kallmeyer Emergency Responders Grant

The Community Foundation of the Hermann Area works to improve the quality of life for individuals in its service area through thoughtful grantmaking and community leadership. It is governed by a Board of Directors, chosen for their knowledge of the area. Grant decisions are made by the grant committee. 

Funding

The total amount to award is $1,032.00.

Applicants may apply for up to $1,032 in funding for this grant cycle.

First Responders

Library Services and Technology Act (LSTA): EZ Grants

State Library of North Carolina
State/Local Government
North Carolina
US $5,000 - US $50,000
The Library Services and Technology Act (LSTA) provides competitive grants to North Carolina libraries to enhance their services and address community needs. Funded by the Institute of Museum and Library Services, these grants promote inclusivity, equitable access to resources, and responsive organizational practices. Libraries can apply for grants ranging from $5,000 to $50,000 to support innovative projects that align with the state's strategic goals outlined in the 2023-2027 LSTA Five Year Plan.
Library Services Technology Access & Digital Literacy

Library Services and Technology Act (LSTA): Project Grants

State Library of North Carolina
State/Local Government
North Carolina
US $50,000 - US $150,000
The Library Services and Technology Act (LSTA) Project Grants offer funding for public, academic, and community college libraries in North Carolina to enhance services and programs. Grants range from $50,000 to $150,000 depending on project duration, with an emphasis on community engagement, equitable access to information, and sustainable practices. Libraries can apply for multi-year grants, fostering partnerships to improve service delivery and address local needs as outlined in the LSTA Five Year Plan.
Library Services Technology Access & Digital Literacy

John C. Slater Predoctoral Fellowship in the History of Science, Technology, and Medicine

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $30,000
The John C. Slater Predoctoral Fellowship, offered by the American Philosophical Society, supports advanced Ph.D. students in the history of science, technology, and medicine. This nine-month residential fellowship includes a $25,000 stipend and a $5,000 travel/research fund. Applicants must not be U.S. citizens or residents and do not receive visa sponsorship. The fellowship emphasizes timely project completion and the importance of access to research facilities in Philadelphia.
History Of Science

Cuba City-City of Presidents Endowment Fund

The Community Foundation of Southern Wisconsin
Private
Grant County, Wisconsin, Lafayette County, Wisconsin
Unspecified amount
The Cuba City-City of Presidents Endowment Fund aims to provide enduring support for community projects, enhancing the beauty of Cuba City. Key initiatives include the Veterans Memorial and local beautification efforts. This fund welcomes diverse contributions, including cash, real estate, and securities, ensuring a legacy of support for future generations. As the endowment grows, it will empower ongoing projects that celebrate and preserve the unique character of Cuba City.
Greening & Beautification

David Center for the American Revolution Predoctoral Fellowship

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $30,000
The David Center for the American Revolution Predoctoral Fellowship at the American Philosophical Society provides a nine-month residential opportunity for Ph.D. candidates focused on the American Revolution and Founding Era. The fellowship offers a $25,000 stipend and a $5,000 travel/research fund. Applicants should demonstrate the necessity of using the center's extensive collections and the ability to complete their project on time. Open to all graduate students, it does not provide visa sponsorship.
American History

Trennert-Iverson Conference Scholarship

Western History Association
Private
New Mexico
US $500
The Trennert-Iverson Conference Scholarship, offered by the Western History Association, provides two annual awards of $500 each to graduate students pursuing M.A. or Ph.D. degrees. This scholarship aims to alleviate the financial burden of attending the annual association conference by covering registration fees and tickets for key events. The scholarship not only supports academic growth but also encourages networking among scholars in the field of western history.
American History

Indian Student Conference Scholarship

Western History Association
Private
Jackson County, Missouri
US $500
The Indian Student Conference Scholarship offers two annual awards of $500 each to Native American students pursuing undergraduate, M.A., or Ph.D. degrees. This funding aims to alleviate the financial burden of attending the annual Western History Association conference. Recipients will also receive coverage for conference registration and tickets to various receptions and luncheons, promoting participation in discussions about western history and fostering academic collaboration.
American History

The Western History Association/Huntington Library Martin Ridge Fellowship

Western History Association
Private
Los Angeles County, California
US $3,500
The Western History Association/Huntington Library Martin Ridge Fellowship offers a $3500, one-month research opportunity at The Huntington Library. Established in honor of Martin Ridge, it supports scholars with a Ph.D. or those at the dissertation stage. The fellowship encourages exploration of western history topics, utilizing specific materials from the library's collections. Recipients are expected to reside continuously at the library during the fellowship, fostering academic collaboration and public education on the diverse histories of the North American West.
American History

Broadwater County Development Corporation: Marketing Grant

Montana Community Foundation
Private
Broadwater County, Montana
Up to US $500
The Broadwater County Development Corporation offers a Marketing Grant aimed at promoting events that boost economic development in Broadwater County. This initiative encourages local organizations to attract visitors, thereby supporting local businesses. Grants are available for up to $500 for BCDC members and $250 for non-members. Eligible applicants must be based in Broadwater County, and the event must be held in the same area. This program is essential for enhancing community engagement and economic vitality.
Economic Services & Development

Governor's Crime Commission Grants: Victims of Crime Act (VOCA)

North Carolina Department of Public Safety
State/Local Government
North Carolina
US $250,000 - US $2,000,000
The Governor's Crime Commission Grants, under the Victims of Crime Act (VOCA), aim to enhance victim assistance programs. This funding prioritizes support for historically marginalized and underserved populations, promoting restoration and healing through targeted services. The Governor's Crime Commission acts as the State Administering Agency, distributing federal and state funds to local agencies and non-profits. Collaboration and evidence-based practices are encouraged to effectively address the needs of crime victims.
Crime Victim Services

Robotic Thoracic Surgery Access Award

The Thoracic Surgery Foundation
Private
United States
US $10,000
The Robotic Thoracic Surgery Access Award, funded by The Thoracic Surgery Foundation, supports underrepresented general thoracic surgeons and cardiothoracic surgery residents in training. This award aims to develop robotic surgical practices through mentorship and training opportunities, providing up to $10,000 for travel expenses. Eligible applicants must demonstrate significant experience in general thoracic surgery and have access to the DaVinci robotic system. This initiative fosters diversity and accessibility in advanced surgical education.
Surgery

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.