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Best Large Grants for Nonprofit Organizations

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$8.25B

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$6K

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$8.25B total
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Montana AmeriCorps State Formula Program Grant

Montana Governor’s Office of Community Service
State/Local Government
Montana
Unspecified amount

Governor’s Office of Community Service aka ServeMontana

Established in 1993, Montana’s Commission on Community Service administers grants under the National and Community Service Trust Act of 1993, amended by the Edward M. Kennedy Serve America Act of 2009 and the Montana Community Service Act of 1994 (MCA 90-14-103). In partnership with the Montana Commission on Community Service, a primary function of the Governor’s Office of Community Service (GOCS) is administering funds to AmeriCorps State programs. 

AmeriCorps Montana

AmeriCorps State grants aid programs in addressing critical community needs, including Education, Disaster Services, Health, Environmental Stewardship, Economic Opportunity, and service to Veterans and Military Families. Grants must align with priorities in the Montana State Service Plan.

Eligible organizations may apply for the following AmeriCorps grants to address pressing needs in Montana: Competitive Program Grants; and Formula Program Grants.

Formula Program Grants

Implement or continue a Formula AmeriCorps State program.

This Notice is the first step an applicant must complete to apply for and receive AmeriCorps State Formula funding. ServeMontana’s role is to solicit, screen, and rank applications. All applications cleared through screening will be ranked and submitted to AmeriCorps for funding determination.

Organizations proposing a new AmeriCorps State program or continuing a currently formula funded program that places AmeriCorps members and operates only in Montana must apply to this competition.

Expectations of All Applicants

  • Address rural, Tribal, underserved, or areas of poverty not currently served by AmeriCorps programs;
  • Clearly connect proposed activities to the needs and priorities in the Montana State Service Plan;
  • Take a collaborative approach to program planning, design, and delivery;
  • Recruit Montanans to serve in their local community; and
  • Design and deliver an inclusive program that is accessible to individuals with disabilities
Military & Veterans Services Environmental Conservation Land / Habitat Conservation +5 more

Safe Haven Baby Box Grant

State of Arkansas Department of Finance and Administration
State/Local Government
Arkansas
Unspecified amount

Safe Haven Baby Box Grant

The Arkansas Safe Haven law allows delivery of a child who is thirty (30) days old or younger to a medical provider, law enforcement agency, fire department, or medical provider staff member. The child may be left in a designated safety device (often called a baby box) that is voluntarily installed by the medical provider, law enforcement agency, or fire department. The baby box must be physically located on a structured wall of or inside a hospital, law enforcement agency, or fire department; and located in an area that is conspicuous and visible to the employees of the hospital, law enforcement agency, or fire department.

The Safe Haven Baby Box Grant program provides funding to eligible organizations to assist with the costs associated with implementing a Safe Haven Baby Box.

Grant funds may only be used for costs associated with implementing a Safe Haven Baby Box that meets the requirements set forth in A.C.A. § 9-34-202. Applicants are eligible to apply for grant funding to cover up to 50% of the cost.

Obstetrics & Neonatal Care Maternal And Perinatal Health

LeverAging StraTegies to Maximize ImpLementation and Effectiveness for HIV (LAST MILE)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The LAST MILE program, initiated by the NIAID, aims to enhance the implementation and effectiveness of HIV prevention and treatment strategies through real-world effectiveness trials. By fostering collaborations and focusing on diverse populations, this initiative seeks to translate clinical findings into practical applications. The program supports research across various disciplines, aligning with the NIH's mission to improve HIV/AIDS outcomes and address associated comorbidities. This multifaceted approach promises to bridge the gap between clinical trials and community-based interventions.
Epidemiology & Public Health Infectious & Parasitic Diseases Health Care Access & Delivery +1 more

Dayton Foundation: Basic Human Needs Grants

The Dayton Foundation
Private
Greene County, Ohio, Miami County, Ohio +3 more
Unspecified amount
The Dayton Foundation's Basic Human Needs Grants provide essential financial support to 501(c)(3) nonprofit organizations in Greater Dayton, focusing on vital necessities like food, shelter, healthcare, and clothing. Grants are awarded quarterly to eligible organizations that demonstrate a commitment to diversity and collaboration in addressing the needs of the homeless, poor, and hungry. This funding also covers operational costs and infrastructure improvements, ensuring organizations can effectively serve their communities.
Domestic Violence Poverty Alleviation & Services Equitable & Affordable Housing +3 more

Longleaf Landscape Stewardship Fund Grant

National Fish and Wildlife Foundation (NFWF)
Private
Acadia Parish, Louisiana, Adams County, Mississippi +389 more
US $250,000 - US $3,000,000
The Longleaf Landscape Stewardship Fund Grant, managed by the National Fish and Wildlife Foundation (NFWF), provides funding for projects aimed at restoring and conserving longleaf pine and bottomland hardwood forests. With approximately $30 million available for 2024, grants range from $250,000 to $3,000,000. This initiative, supported by various federal and private entities, emphasizes the importance of ecological preservation and sustainable land management practices.
Forestry Habitat & Ecosystem Restoration

Housing Opportunities for People Living with HIV/AIDS

District of Columbia Department of Health
State/Local Government
District of Columbia, Prince George's County, Maryland
US $300,000 - US $8,000,000

Housing Opportunities for People Living with HIV/AIDS

This funding opportunity is to support rental assistance and housing-related supportive services for eligible District and Maryland residents living with HIV through the Housing Opportunities for Persons with AIDS program.

The mission of DC Health is to promote and protect the health, safety, and quality of life of residents, visitors, and those doing business in the District of Columbia. The agency is responsible for identifying health risks; educating the public; preventing and controlling diseases, injuries, and exposure to environmental hazards; promoting effective community collaborations; and optimizing equitable access to community resources.

The mission of HAHSTA is to protect and improve the health of District residents by preventing, diagnosing, treating, and reducing the transmission of HIV, viral hepatitis, sexually transmitted diseases, and tuberculosis, while ensuring access to high-quality, coordinated, and culturally responsive care and support services for individuals and communities most impacted by these conditions.

The mission of the CBHCP Division is to strengthen the HIV service delivery system by expanding access to stable housing, enhancing organizational and workforce capacity, and fostering strategic community partnerships that improve health outcomes, promote service coordination, and address structural barriers impacting people living with HIV in the District of Columbia.

The mission of the Housing Opportunities for Persons with AIDS (HOPWA) program is to provide stable, affordable housing and housing-related supportive services for low-income individuals living with HIV and their households, recognizing housing stability as essential to improved health outcomes, sustained engagement in care, and overall well-being

HIV / AIDS Supportive Housing & Shelters

Montana AmeriCorps State Competitive Program Grant

Montana Governor’s Office of Community Service
State/Local Government
Montana
Unspecified amount

Governor’s Office of Community Service aka ServeMontana

Established in 1993, Montana’s Commission on Community Service administers grants under the National and Community Service Trust Act of 1993, amended by the Edward M. Kennedy Serve America Act of 2009 and the Montana Community Service Act of 1994 (MCA 90-14-103). In partnership with the Montana Commission on Community Service, a primary function of the Governor’s Office of Community Service (GOCS) is administering funds to AmeriCorps State programs. 

AmeriCorps Montana

AmeriCorps State grants aid programs in addressing critical community needs, including Education, Disaster Services, Health, Environmental Stewardship, Economic Opportunity, and service to Veterans and Military Families. Grants must align with priorities in the Montana State Service Plan.

Eligible organizations may apply for the following AmeriCorps grants to address pressing needs in Montana: Competitive Program Grants; and Formula Program Grants.

Competitive Program Grants

Implement or continue a Competitive AmeriCorps State program.

This Notice is the first in a multistep process an applicant must complete to apply for and receive AmeriCorps State Competitive funding. ServeMontana’s role is to solicit, screen, and rank applications. This process is only for ranking; no funding will be awarded from this solicitation. All applications cleared through screening will be ranked and submitted to compete nationally for funding. 

Organizations continuing a competitively funded program or proposing an AmeriCorps State program that operates only in Montana must apply to this competition.

Expectations of All Applicants

  • Address rural, Tribal, underserved, or areas of poverty not currently served by AmeriCorps programs;
  • Clearly connect proposed activities to the needs and priorities in the Montana State Service Plan;
  • Take a collaborative approach to program planning, design, and delivery;
  • Recruit Montanans to serve in their local community; and
  • Design and deliver an inclusive program that is accessible to individuals with disabilities.
Land / Habitat Conservation Disaster Preparedness Health Disparities & Social Determinants of Health +5 more

SD Workforce Education: Local Education Agency (LEA) Grant

South Dakota Department of Education
State/Local Government
South Dakota
Up to US $225,000

Career and Technical Education

The goal of the South Dakota Department of Education is for all students to graduate college, career, and life ready. The Division of College, Career and Student Success provides support for students' preparations for postsecondary education and the workforce. Services are connected to approved Career & Technical Education (CTE) programs, work-based learning, student organizations and more. In-line with the department's aspiration, DCCSS works to ensure students not only graduate from high school, but that they are prepared to navigate the transitions and life events that come after high school.

Workforce Education Grants

In 2013, the South Dakota Legislature established the Workforce Education Fund through SB 235. Part of that fund was designated to provide grants for Career & Technical Education (CTE) programs in secondary schools.

The Workforce Education Grants provide school districts and private, nonprofit entities who provide specialized training in South Dakota the opportunity to make transformative change in career and technical education programs. High quality CTE programs give students the knowledge, skills and experiences to be well prepared for postsecondary education and the workforce. Partnerships among secondary education, postsecondary education, and business & industry lay the foundation for modern CTE programs.

Grant Purpose & Eligibility

The Workforce Education Grants are designed to support and align secondary school CTE systems with South Dakota's postsecondary education programs and workforce needs, developing the state's talent pipeline for workforce development and economic growth. Projects are meant to serve middle and high school students.

Eligible applicants are Local Education Agencies (LEAs) with projects designed to serve middle and high school students. The LEAs who are awarded grants will serve as fiscal agents through the completion of their projects. All applications must demonstrate commitment by all grant partners to the grant project and its sustainability following the conclusion of the grant.

Education - Higher Education Workforce Preparation & Job Readiness Career / College Preparation +3 more

Department for Public Health (DPH) - Rural Health Transformation Program Funding Opportunity to Establish or Expand Community Paramedicine Programming

Kentucky Cabinet for Health and Family Services
State/Local Government
Kentucky
Up to US $20,000,000

Kentucky Cabinet for Health and Family Services

Our mission is to be a diverse and inclusive organization providing programs, services and supports that protect and promote the health and well-being of all Kentuckians and their communities.

Department for Public Health (DPH) - Rural Health Transformation Program Funding Opportunity to Establish or Expand Community Paramedicine Programming

About the Program

This project is 100% funded by the Centers for Medicare and Medicaid Services of the U.S. Department of Health and Human Services (HHS) for a total of $212.9 million in budget year 1 with 100% by CMS/HHS. The RHTF grant spans five budget periods aligned with federal fiscal years (FY2026–FY2030). Funding is disbursed annually by CMS based on achievement of performance metrics.

Funding is designed to support early program development and scaling. Community paramedicine programs are not expected to be fully sustainable during initial funding periods. Awards may vary depending on the proposed budget provided by the applicant and additional funding will be provided in subsequent years.

Program Objectives

Funded programs must demonstrate their willingness and ability to:

  • Design and deliver community paramedicine services that address low-acuity, preventative, and high-utilization patient needs in Kentucky’s rural communities.
  • Reduce unnecessary emergency department utilization and repeat visits after discharge by supporting community members where they are.
  • Strengthen partnerships with rural service sites such as Local Health Departments, Federally Qualified Health Centers, rural clinics, and behavioral health partners, including Community Mental Health Centers (CMHCs).
  • Connect community members to the right care before and after emergencies by repositioning EMS as a front-line connector to care.
  • Operate in a cost-effective, sustainable, and compliant manner. Compliance is defined as adherence to KBEMS standards for EMS agencies. 
Rural Health Care Preventative Healthcare Chronic Illnesses +2 more

Nantucket Fund Grants

Community Foundation for Nantucket
Private
Nantucket County, Massachusetts
Unspecified amount
The Nantucket Fund Grants, offered by the Community Foundation for Nantucket, aim to enhance the quality of life for island residents through targeted community projects. Grants are available to 501(c)(3) organizations, municipalities, and religious entities addressing critical needs such as mental health, housing, and senior well-being. The initiative encourages innovative, sustainable solutions that leverage additional support while fostering collaboration among local nonprofits to maximize impact and minimize service duplication.
Intellectual / Developmental Disabilities Addiction & Substance Use Disorders Real Estate & Housing +4 more

Food Farmacy Project

Montana Department of Public Health and Human Services
State/Local Government
Montana
US $5,000

About Us

At the Montana Department of Public Health and Human Services (DPHHS), we are dedicated to our mission of serving Montanans in their communities to improve health, safety, well-being, and empower independence. As the largest executive branch agency in the state, our broad reach allows us to provide essential, community-based support where and when it matters most. Our DPHHS team is passionate about improving our clients’ lives and helping them build a more secure and independent future.

Food Farmacy Project

Support food insecure patients to access food resources. Using a team-based care approach, a clinic will partner with a local food pantry to improve access to healthier food for patients with high blood pressure and/or high cholesterol. Funds cannot be used to directly purchase food.

Basic Human Needs Food Access & Hunger Food Delivery & Distribution Services +2 more

Trinity Grants: Racial Justice Initiative

Trinity Church Wall Street
Private
Bronx County, New York, Kings County, New York +3 more
US $80,000 - US $350,000
The Trinity Grants: Racial Justice Initiative, spearheaded by Trinity Church Wall Street, aims to foster equitable justice systems through community-driven approaches. Focused on mental health, safety, and reducing incarceration, this initiative emphasizes support for marginalized groups, particularly people of color. It addresses the need for restorative justice, legislative reforms, and comprehensive support for those impacted by the criminal legal system, aiming to transform communities and enhance public safety.
Criminal Justice System Reform Reentry Services Immigrant Services +5 more

NSEDC: Water and Sewer Fund Grant

Norton Sound Economic Development Corporation
Private
Kusilvak Census Area, Alaska, Nome Census Area, Alaska
Up to US $1,000,000
The NSEDC Water and Sewer Fund Grant provides critical financial support for water and sewer projects in Norton Sound communities, allocating $1 million for upgrades or new construction. Additionally, it offers emergency funding up to $300,000 for urgent health and infrastructure needs. This program, renewed in 2024 and set to expire in 2029, aims to enhance community health and financial stability through essential water and sewer improvements.
Water Resource Management Waste Management

Emerging Contaminants in Small or Disadvantaged Communities (EC-SDC) Grants - Illinois

Illinois Environmental Protection Agency
State/Local Government
Illinois
Up to US $6,650,000

Emerging Contaminants in Small or Disadvantaged Communities (EC-SDC) Grants - Illinois

The Emerging Contaminants in Small or Disadvantaged Communities (EC-SDC) Grant will utilize grant funds provided by the U.S. Environmental Protection Agency (EPA) to assist small or disadvantaged communities in the State of Illinois where emerging contaminants have become a problem or appear likely to become a problem in the near term. The Illinois EPA will use the awarded funds to make sub-awards to eligible water systems for projects that will further quantify these problems and help to remediate them. 

The EC-SDC Grant Program will be utilizing $21,806,000 from the EPA EC-SDC Grant Program which congress appropriated from the State and Tribal Assistance Grant (STAG). The Illinois EPA expects to award a total of $21,806,000.00 in grant awards with an award ceiling of $6,650,000.00 per applicant. 

Sanitation & Clean Drinking Water Environmental Contamination & Pollution Water Resource Management

Old National Bank Foundation Sponsorships

Old National Bank
Corporate
Allen County, Indiana, Berrien County, Michigan +58 more
Unspecified amount
The Old National Bank Foundation provides sponsorships to enhance community initiatives in Indiana, Illinois, Kentucky, Michigan, Minnesota, and Wisconsin. Their mission focuses on social responsibility, supporting underrepresented groups, and aligning with the Community Reinvestment Act. Sponsorships cover events such as fundraisers and sporting events, emphasizing active engagement and measurable impact. The Foundation aims to improve quality of life through strategic partnerships and meaningful contributions.
Financial Literacy Economic Services & Development Workforce Preparation & Job Readiness +2 more

Recycling Grant to Responsible Units

Wisconsin Department of Natural Resources
State/Local Government
Wisconsin
Unspecified amount
The Wisconsin Recycling Grant Program, managed by the Wisconsin Department of Natural Resources, offers financial support to cities, towns, villages, counties, tribes, and solid waste management systems. This initiative aims to enhance residential recycling and yard waste programs by covering essential costs for managing recyclable materials, including paper, plastics, and glass. By fostering effective recycling systems, the program seeks to improve material recovery and promote sustainable waste management practices throughout Wisconsin.
Waste Management Recycling

Used Oil Collection Gift Grant Program

New Hampshire Department of Environmental Services
State/Local Government
New Hampshire
Up to US $5,000
The Used Oil Collection Gift Grant Program, managed by the New Hampshire Department of Environmental Services, provides gift grants to municipalities for establishing and improving used oil collection centers. These grants aim to support Do-It-Yourselfers in properly recycling their used oil at licensed facilities. Eligible entities include towns, counties, and registered inspection stations, with most grants not exceeding $2,500, while multi-town centers may qualify for up to $5,000.
Waste Management Recycling

SCCF: Health & Human Services Grant

Steuben County Community Foundation
Private
Steuben County, Indiana
US $3,000 - US $10,000
The Steuben County Community Foundation offers the Health & Human Services Grant Cycle to support projects that enhance physical and mental health, provide essential healthcare services, and address basic human needs like hunger and homelessness in Steuben County. Nonprofits serving the area are eligible, with a focus on collaborative initiatives that improve quality of life and tackle root causes. This funding seeks to empower organizations committed to making a meaningful impact in the community.
Human & Social Services Health & Medicine Mental Health & Psychiatric Diseases +6 more

Small Harbor Improvement Program (SHIP) Grant

Maine Department of Transportation
State/Local Government
Maine
Up to US $250,000

Small Harbor Improvement Program

The Small Harbor Improvement Program (SHIP) promotes economic development, public access, improved commercial fishing opportunities and works to preserve, and create, infrastructure at facilities in tidewater and coastal municipalities. The SHIP program assists municipalities in improving or creating facilities, such as public wharves, piers, landings and boat ramps. There is a required 50% local share under this program. The SHIP program can provide up to $250,000 in assistance towards eligible projects.

Ongoing Program for Future Funding Assistance

This grant application is open to tidewater communities that can demonstrate a need to improve economic activity and access to a tidewater river or the ocean on publicly-accessible property. Typical types of projects funded under this program include commercial and municipal wharf improvements, hoist systems, boat ramps, gangways, stairwells to clam flats, piling replacements, etc.

The goal of this program is to promote economic development, and improve public marine infrastructure and public access. MaineDOT urges each community to contact us as soon possible with your project ideas/needs to begin the process for potential inclusion in upcoming budgets. MaineDOT will schedule site visits as needed once a letter of intent has been filed. Once a letter of intent project has been deemed eligible, the community will be able to submit an application.

Marine / Ocean Conservation Fish Conservation Public Infrastructure +3 more

Shumaker Family Foundation: Social Justice & Education Grants

Shumaker Family Foundation
Private
Wyandotte County, Kansas
US $10,000 - US $30,000
The Shumaker Family Foundation supports social justice, environmental justice, and education initiatives. Founded in 2003, it emphasizes programs that promote equity, particularly for marginalized communities. Grants typically range from $10,000 to $30,000, focusing on systemic solutions and cultural shifts. The foundation prioritizes organizations with 501(c)(3) status and those led by community members. They prefer not to be the sole funder, valuing partnerships that enhance the capacity of grantees.
Education Educational Access & Equity Art Education +7 more

Francis Courtney Educational Fund Grant

Housing Pathways
Private
United Kingdom
£500 - £1,500
The Francis Courtney Educational Fund Grant, managed by Housing Pathways, supports individuals under 25 in the London Borough of Ealing with scholarships, bursaries, and one-off grants for educational expenses. Applications are welcomed from individuals and organizations that align with the fund's mission. Priority is given to residents of Southall and Norwood Green, particularly those in financial need. This initiative aims to foster educational opportunities and assist beneficiaries in their professional pursuits.
Education Poverty Alleviation & Services Supportive Housing & Shelters +6 more

Capacity Building Initiative (CBI)

Chesapeake Bay Trust
Private
Delaware, District of Columbia +4 more
Up to US $150,000
The Capacity Building Initiative (CBI) by the Chesapeake Bay Funders Network aims to enhance the organizational capacity of groups working towards community well-being and natural resource management. Funded projects may include strategic planning, staff training, and technology assistance, with funding requests typically capped at $40,000 for nonprofits and $150,000 for local governments. Eligible applicants include nonprofits and local governments operating within the Chesapeake watershed, focusing on water and natural resource goals.
Natural Resources Water Resource Management

Edward Byrne Memorial Justice Assistance Grant (JAG)

Ohio Office of Criminal & Justice Services
State/Local Government
Ohio
US $4,553 - US $150,000

2026 Edward Byrne Memorial Justice Assistance Grant Program (JAG)

OCJS and JAG

The Ohio Office of Criminal Justice Services (OCJS) is a division of the Ohio Department of Public Safety. By statute, OCJS is the lead justice planning and assistance office for the state, administering millions of dollars in state and federal criminal justice funding every year. OCJS also evaluates programs and products, develops training, resources, and best practices for criminal justice professionals and communities. OCJS has been designated by Governor Mike DeWine to administer the FY 2026 Edward Byrne Memorial Justice Assistance (JAG) Grant Program.

Proposed to streamline justice funding and grant administration, the JAG Program allows states, tribes, and local governments to support a broad range of activities to prevent and control crime based on their own local needs and conditions. JAG blends the previous Byrne Formula and Local Law Enforcement Block Grant programs so that agencies can prioritize their funding needs and choose where to place justice funds.

In 2024, OCJS implemented its strategic plan (PDF). The action items included identifying priority areas for funding and encouraging projects to use evidence-based practices in their funded programs. The “Goals, Priorities and Requirements” section of this document outlines these priorities, and references evidence-based practices for OCJS funding areas. Fiscal year 2026 applicants must continue to follow these most recent guidelines.

Crime & Justice Crime Victim Services Police & Law Enforcement +4 more

Iowa Tree Planting Grant

Iowa Department of Natural Resources
State/Local Government
Iowa
US $10,000 - US $30,000

Iowa Department of Natural Resources

The Iowa Department of Natural Resources (DNR) manages fish and wildlife programs, ensures the health of Iowa’s forests and prairies, and provides recreational opportunities in Iowa’s state parks.

Just as importantly, the DNR carries out state and federal laws that protect air, land and water through technical assistance, permitting and compliance programs. The DNR also encourages the enjoyment and stewardship of natural resources among Iowans through outreach and education. Our mission is to conserve and enhance our natural resources in cooperation with individuals and organizations to improve the quality of life in Iowa and ensure a legacy for future generations.

IRA Iowa Tree Planting Grant

The Iowa Department of Natural Resources, through the USDA Forest Service & National Association of State Foresters 2023 Inflation Reduction Act (IRA), received funds to plant trees in public spaces.

The Iowa Tree Planting Grant provides reimbursable grants to purchase trees, mulch, tree staking/protection and supplemental watering by contractor or city staff. The grant is a two-year program.

The Iowa Tree Planting grants are available to community governmental entities, volunteer organizations, and service organizations involved with local urban and community forest services, to plant trees on publicly owned properties within the community to diversify the tree canopy, increase tree benefits, help with energy costs and health disparities, and increase access to parks and nature. 

Environmental Education Forestry Greening & Beautification +1 more

Household Hazardous Waste (HHW) Education Grant

Pennsylvania Department of Environmental Protection (DEP)
State/Local Government
Pennsylvania
Up to US $75,000

Act 101, Section 901, Household Waste (HHW) Education Grants. Counties are eligible for 80 percent reimbursement for educational programs on household hazardous waste and pollution prevention.

Waste Management Recycling

Alabama State Council on the Arts Visual Arts - Project Grants

Alabama State Council on the Arts
State/Local Government
Alabama
US $1,000 - US $10,000
The Alabama State Council on the Arts Visual Arts - Project Grants support a variety of artistic activities aimed at enhancing the cultural landscape of Alabama. These grants encourage projects such as festivals, performances, and exhibitions, fostering public engagement with the arts. By promoting excellence and accessibility in arts education, the Council aims to recognize and preserve the state's rich artistic traditions while driving economic vitality through cultural initiatives.
Visual Arts Media Arts Photography +5 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.