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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,483 Results based on applied filters

Joseph A. Catrambone Trade & Vocational Scholarship

The Community Foundation Martin – St. Lucie
Private
United States
Unspecified amount

Joseph A. Catrambone Trade & Vocational Scholarship

Anyone pursuing a degree or certification in a trade or vocation.

Award:

  • Full need is taken into account – awards amounts are based on need.
Vocational & Trade Education

CFEC: Emergency Grants

Community Foundation of Elkhart County
Private
Elkhart County, Indiana
US $250 - US $25,000
The CFEC Emergency Grants provide crucial support for nonprofits in Elkhart County facing unexpected challenges. These grants are designed to assist organizations responding to urgent events like natural disasters, theft, or facility issues that threaten their operations. By offering rapid financial assistance, the program ensures that vital community services can continue even in times of crisis, helping nonprofits maintain stability and fulfill their missions effectively.
Disaster Relief / Humanitarian Aid

Dr. Harve E. & Joyce E. Rawson Endowment

Community Foundation of Madison and Jefferson County
Private
Franklin County, Indiana
Unspecified amount

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Dr. Harve E. & Joyce E. Rawson Endowment

Be enrolled at Franklin College in Franklin, Indiana. Contact Franklin College admission office.

Education - Higher Education

PLTW Gateway - Program Expansion (Phillips 66)

Project Lead The Way Inc
Private
Adams County, Colorado, Andrews County, Texas +50 more
Up to US $10,000
The PLTW Gateway Program Expansion, funded by Phillips 66, aims to enhance educational equity by supporting middle schools in STEM. With a total award of $10,000, the initiative focuses on expanding existing PLTW Gateway programs, particularly for schools serving high-need student populations. This partnership encourages a diverse workforce by providing opportunities for girls and people of color, ensuring they explore various STEM pathways during critical developmental years.
STEM / STEAM Education

Community Development Block Grant - Economic Development (NE)

Nebraska Department of Economic Development
State/Local Government
Adams County, Nebraska, Antelope County, Nebraska +87 more
US $125,000 - US $1,015,000
The Community Development Block Grant - Economic Development (NE) aims to enhance Nebraska's economic base by supporting for-profit businesses that create quality jobs for low- and moderate-income individuals. With maximum project costs of $1,000,000 and a minimum of $125,000, these funds are crucial for local development. The initiative ensures compliance with federal regulations and promotes timely use of resources, thereby fostering economic prosperity across communities.
Economic Services & Development

The Toy Foundation Program - Apply for Toys

The Toy Foundation
Private
Alabama, Allegheny County, Pennsylvania +34 more
Unspecified amount in in-kind support
The Toy Foundation Program offers a unique opportunity for nonprofit organizations to apply for toy donations to support children in need. The application period runs from January to June, with approved applicants receiving toys by the end of the year. This initiative, part of the Toy Chest program, has positively impacted over 35 million children since 2003, promoting play as essential for emotional and educational development.
Youth Services

Indianapolis Center For Congregations: Resource Grants

Indianapolis Center for Congregations
Private
Indiana
Up to US $25,000
The Indianapolis Center for Congregations offers Resource Grants to support Indiana congregations in addressing challenges and opportunities. These matching grants, capped at $25,000, allow congregations to fund essential resources and activities. The program is part of the Center's mission to strengthen congregational work and is funded by the Lilly Endowment Inc. Eligible applicants must demonstrate alignment with their mission and secure endorsements from their leadership.
Christianity

Ohio Physicians of Tomorrow Scholarship

American Medical Association Foundation
Private
Ohio
US $10,000
The Ohio Physicians of Tomorrow Scholarship, established by the AMA Foundation, aims to support future physician leaders through substantial tuition assistance. Eligible applicants must be enrolled in an accredited U.S. medical school, entering their final year, and demonstrate financial need. This scholarship fosters a commitment to health equity and encourages involvement in organized medicine. Applications are typically due in the first quarter of each year, ensuring that funds are directed towards tuition costs only.
Medical Education & Professional Training

Carnegie-Whitney Grant

American Library Association (ALA)
Association/Society
United States
Up to US $5,000
The Carnegie-Whitney Grant, established by Andrew Carnegie in 1902, supports the creation of bibliographical aids for American libraries. Grants cover the preparation costs of reading lists and indexes, enhancing access to library resources. Eligibility requires projects to stimulate library use and be broadly appealing, with a focus on national distribution. Notably, completed works and projects under contract are ineligible. The fund encourages innovation in library resource development, welcoming applications from individuals and organizations.
Library & Information Science Library Services

Terry & Wanda Wood Memorial Scholarship

Community Foundation of Madison and Jefferson County
Private
United States
US $7,500

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Terry & Wanda Wood Memorial Scholarship

Criteria evaluated:

  • Work ethic and ambition, desire to pursue a trade, and financial need

Required materials: 

  • Essay of up to 250 words describing the applicant’s career path plans, 
  • 2 letters of recommendation from teachers and/or counselors, and 3) FAFSA SAI PDF upload

Scholarship amount:

  • $7,500 | 1 scholarship
Vocational & Trade Education

CCF: Women’s Giving Circle Grants

Connecticut Community Foundation
Private
Litchfield County, Connecticut, New Haven County, Connecticut
US $5,000 - US $15,000

CCF: Women’s Giving Circle Grants

The Women’s Giving Circle at Connecticut Community Foundation was formed in 2017 to bring women together to learn about issues affecting women and girls in Greater Waterbury and the Litchfield Hills, to join their dollars, and to make grants that will improve lives. When it is time to make grants, Circle members decide together the issues they want to support, such as employment, education, pay equity, housing, parenting or women’s health. Circle members review grant applications and make funding decisions together. The Women’s Giving Circle is open to anyone who cares about women and girls in Greater Waterbury and the Litchfield Hills.

Grant proposals are accepted once annually.

What is the average grant amount?

The average amount is between $5,000 and $15,000. Please review the grant guidelines for the funding area you plan to apply to for an average amount. Grants for larger amounts can be considered. However, for those, please contact our staff to discuss the project in advance of submission.

Women & Girl Services

PLTW Launch - Program Expansion ( L3Harris Technologies

Project Lead The Way Inc
Private
Alexandria City, Virginia, Amherst County, Virginia +64 more
Up to US $5,000
L3Harris Technologies is collaborating with Project Lead The Way (PLTW) to expand STEM education for PreK-12 students. This initiative aims to inspire young learners through enhanced PLTW programs starting in the 2025-2026 academic year. Eligible schools, including public and charter institutions in specified counties, can receive grants of $5,000 to support program expansion. The focus is on providing resources for new modules, teacher training, and ensuring access for diverse and economically challenged communities.
STEM / STEAM Education

Future Leaders Internship (FLI) Grants

Dekalb County Community Foundation
Private
DeKalb County, Illinois
Up to US $500

What is DCNP?

The DeKalb County Nonprofit Partnership (DCNP) exists to help strengthen nonprofit organizations in DeKalb County. Stronger organizations that are effective, well-run, resilient, efficient, and sustainable can enhance the quality of life in DeKalb County – which is our ultimate purpose!

Mission Statement:

The DeKalb County Nonprofit Partnership strengthens the nonprofit sector through leadership, professional development, and collaboration.

Future Leaders Internship (FLI) Grants

DCNP members can apply for matching funds (up to $500, dollar for dollar) to support paid internships. Applications are accepted year-round. 

Apprenticeship & Internship Programs

G. Ernest and Bernadine Rightley Scholarship

Marshall County Community Foundation Inc
Private
United States
Unspecified amount
The G. Ernest and Bernadine Rightley Scholarship, administered by the Marshall County Community Foundation, aims to support graduating seniors from Marshall County schools. This scholarship is designed for local residents who are entering their first year of study at an accredited college or university. The foundation is committed to fostering philanthropy and providing opportunities for students to pursue higher education, thereby investing in the future of the community.
Education - Higher Education

GCRA- Downtown Events Grant Program

City of Gainesville Parks, Recreation and Cultural Affairs Department (PRCA)
State/Local Government
Alachua County, Florida
Up to US $5,000
The GCRA Downtown Events Grant Program offers up to $5,000 to support events in Downtown Gainesville from January 31 to June 30, 2025. Administered by the City of Gainesville's Community Reinvestment Area, this program aims to enhance cultural activities in publicly owned spaces. With $30,000 allocated from FY24 funds, applications will be accepted on a rolling basis until funding is exhausted. This initiative fosters collaboration among community organizations to enrich the local cultural landscape.
Arts / Culture Access & Participation

Dr. David R. Barkmeier Top Research Universities Scholarship

Marshall County Community Foundation Inc
Private
United States
Unspecified amount
The Dr. David R. Barkmeier Top Research Universities Scholarship, offered by the Marshall County Community Foundation, provides funding for students attending prestigious universities, including those in the Association of American Universities. This scholarship supports graduates from Marshall County high schools who can demonstrate residency and is renewable for previous recipients who meet eligibility criteria. It aims to foster academic excellence and assist local students in achieving higher education.
Education - Higher Education

Legal Counsel in Administration of Blue Buffers Program

Enterprise Community Partners Inc
Private
New York
Unspecified amount

Enterprise Community Partners

Enterprise Community Partners is a national nonprofit that exists to make a good home possible for the millions of families without one. Home is where life happens, where plans are made, and futures begin. It is the foundation for dignity, health, education, wealth, and community. Yet rents keep going up, paychecks don’t keep pace, and good homes in strong neighborhoods are increasingly out of reach.

The system doesn’t work. It must be changed, and it must be changed by us.

Enterprise has the breadth, scale, and expertise to do it. We support community development organizations on the ground. We aggregate and invest billions to improve housing and strengthen communities across the U.S. We advance housing policy at every level of government. We build and manage communities ourselves. Everything we do is informed by the residents we serve.

Together with our partners, we focus on the greatest need — the massive shortage of affordable rental homes — to achieve three goals:

  • Increase the supply of affordable homes
  • Advance racial equity after decades of systematic racism in housing
  • Support residents and strengthen communities to be resilient to the unpredictable, and make upward mobility possible

Since 1982, we have invested $92.0 billion and created 1.1 million homes across all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. We do all this to make home and community places of pride, power, and belonging.

Legal Counsel in Administration of Blue Buffers Program

Enterprise Community Partners, Inc. ("Enterprise") was selected as a subrecipient of New York State Housing and Community Renewal to administer the Blue Buffers Program pursuant to a subaward. To fulfill its obligations, Enterprise formed a special purpose entity, Enterprise Assisted Properties, LLC (“EAP”).

Enterprise Assisted Properties ("EAP") has initiated a Request for Proposal (“RFP”) process to identify a legal representation panel which will be able to represent EAP in carrying out the New York State Blue Buffers Voluntary Risk Property Buyout Program.

Legal Services

GCRA- Community Partnership Grant Program

City of Gainesville Parks, Recreation and Cultural Affairs Department (PRCA)
State/Local Government
Alachua County, Florida
Up to US $5,000
The GCRA Community Partnership Grant Program provides up to $5,000 in matching funds to support local organizations in delivering special programming within the GCRA District. Administered in four cycles throughout the year, the program encourages community engagement, economic development, and cultural maintenance. Organizations can combine GCRA and SEAS grants for the same event, ensuring funds are allocated to different costs, thereby enhancing community experiences and promoting inclusivity.
Arts / Culture Access & Participation

CJP Funding: Small Grants

Center for Jewish Philanthropy of Greater Phoenix
Private
Gila County, Arizona, Maricopa County, Arizona +1 more
Up to US $3,000
The Center for Jewish Philanthropy of Greater Phoenix offers the Small Grants Program to support initiatives that strengthen the local Jewish community. With funding up to $3,000, eligible organizations can apply for projects that address urgent needs or leverage matching grants. Since 2017, this streamlined process prioritizes projects that directly impact the Greater Phoenix Jewish community, reinforcing CJP's commitment to innovation, emergency response, and sustainable local Jewish life.
Judaism

Next Generation Giving Circle

Gaston Community Foundation
Private
Gaston County, North Carolina
Unspecified amount
The CFGC: Next Generation Fund Grant, established by the Gaston Community Foundation, supports charitable initiatives primarily in Gaston County. Since 2000, it has awarded over $193,000 to local nonprofits focused on children's welfare, environmental improvements, and crisis relief. In 2023, the fund emphasizes Health and Wellness, encouraging collaboration among organizations to maximize community impact. This grant fosters grassroots support and sustainable projects, ensuring that resources are used effectively to benefit the county's residents.
Wellness & Healthy Living

Alabama Power Foundation: Field Trip Grants

Alabama Power Foundation
Corporate
Alabama
Up to US $2,500
The Alabama Power Foundation offers Field Trip Grants aimed at enhancing educational experiences for K-12 students. These grants support trips to historical sites, museums, and nature preserves, fostering curiosity and engagement. Priority is given to teachers in Title I schools, ensuring equitable access to enriching experiences. By bridging educational gaps, the foundation empowers teachers to create lasting memories and deepen students' understanding of various subjects, ultimately contributing to the betterment of communities across Alabama.
Academic Success & Enrichment

CLG - Certified Local Government Grants Program

Illinois Department of Natural Resources
State/Local Government
Illinois
Up to US $30,000
The Certified Local Government Grants Program in Illinois supports city and county governments in developing local preservation projects. Funded by federal resources from the National Park Service, this program ensures at least 10% of Illinois’ federal allocation is dedicated to participating Certified Local Governments (CLGs). With 81 CLGs currently involved, the Illinois Department of Natural Resources anticipates $110,000 to $150,000 in competitive grants for this round, fostering the preservation of historic resources.
Historic Preservation

Ryan White Dental RFA

Seattle King County Department of Public Health
State/Local Government
Island County, Washington, King County, Washington +1 more
Unspecified amount

Ryan White Dental RFA

The Ryan White Part A Program at Public Health – Seattle & King County (PHSKC) funds the Lifelong Dental Program (LDP). LDP is a comprehensive oral health access program whose aim is to support low-income HIV-positive individuals living in King, Snohomish, and Island counties with access to oral health care services. The program covers the costs of dental procedures that are deemed medically necessary and time sensitive by participating dental providers and clinics.

Specific coverage limits for this particular Work are:

Commercial General Liability, to include Products and Completed Operations, in the amount of $1,000,000 combined single limit; $2,000,000 aggregate

Workers' Compensation and Stop-Gap Employer's Liability for a limit of $1,000,000

Professional Liability coverage of at least $1,000,000

Automobile Liability: If driving as part of the Scope of Work $1,000,000 combined single limit per accident for bodily injury and property damage. In the event that services delivered pursuant to this Contract involve the transportation of clients by Contractor personnel in Contractor-owned vehicles or non-owned vehicles, the limit  shall be no less than $3,000,000 combined single limit per accident for bodily injury and property damage.

Include Public Health – Seattle & King County 401 5th Ave, Ste. 1120, Seattle WA 98104, in the Certificate Holder box.

Provide an additional Insured endorsement to be included with the certificate of insurance, “CG 2010 11/85" or its equivalent is required which may include a blanket endorsement.

Total Amount of Federal Award: $ 1,987,222

Through this Request for Applications (RFA), PHSKC’s Ryan White Part A (RWPA) Program is seeking applications from dental providers/dental clinics interested in providing oral health services to low-income people living with HIV in the Seattle Transitional Grant Area (TGA) of King, Snohomish, and Island counties. PHSKC seeks to fund and contract with a varied group of providers capable of serving diverse communities and geographic areas within the TGA.

The dollar amount is based on the number of patients the provider’s practice can serve, provider specializations, location, and other factors. Providers will have this set amount of funds to use towards the oral health needs of LDP patients during the contract year.

Dental Health

Illuminations Grant for Black Trans Women Visual Artists

Queer Art
Private
American Samoa, Guam +4 more
US $10,000
The Illuminations Grant for Black Trans Women Visual Artists, a $10,000 annual grant, supports early-career Black trans women artists in the U.S. whose contributions to visual arts are often overlooked. Established in partnership with notable figures, this grant not only provides funding but also offers professional development resources. In its fifth year, it aims to address systemic barriers and enhance representation in the arts, with additional awards for finalists to further their artistic journeys.
Visual Arts

World Trade Center Scholarship (NJ)

New Jersey Higher Education Student Assistance Authority
State/Local Government
New Jersey, United States
Unspecified amount
The World Trade Center Scholarship in New Jersey provides financial support to dependent children and surviving spouses of residents who lost their lives in the September 11 attacks. Administered by HESAA, this scholarship covers tuition, fees, and other educational costs at eligible institutions. Applicants must be full-time students and maintain satisfactory academic progress. The award amount varies each year based on funding and need, ensuring that assistance is available to those who have lost financial support due to these tragic events.
Education - Higher Education

Governor's Urban Scholarship (NJ)

New Jersey Higher Education Student Assistance Authority
State/Local Government
New Jersey
Unspecified amount
The Governor's Urban Scholarship (NJ) is a merit-based program by HESAA designed to support high-achieving students from designated New Jersey communities. Eligibility is determined by high school rankings, requiring students to be in the top 5% with a GPA of 3.0 or higher. No application is needed; schools submit eligible candidates directly to HESAA. This initiative not only promotes academic excellence but also enhances educational opportunities for students in underserved areas.
Education - Higher Education

PLTW Launch - New Program (John Deere)

Project Lead The Way Inc
Private
Barnes County, North Dakota, Black Hawk County, Iowa +22 more
US $10,000
The PLTW Launch program, in partnership with the John Deere Foundation, aims to enhance STEM education access for underserved communities. This initiative supports schools in implementing PLTW Launch modules, fostering equitable opportunities for students. With a commitment to enroll at least 50% of students from the Free and Reduced Lunch program, the program focuses on real-world skills development to prepare youth for future challenges. The goal is to empower one million students by 2030.
STEM / STEAM Education

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.