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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,499 Results based on applied filters

CHCF Innovation Fund Grant

California Health Care Foundation
Private
California
Up to US $400,000
The CHCF Innovation Fund Grant aims to enhance healthcare access and quality for Californians by investing in early- to growth-stage companies. It focuses on technologies developed by diverse founders who understand community challenges, particularly in California's Medicaid ecosystem. The fund seeks partners committed to improving care quality, reducing costs, and ensuring access for low-income populations. This initiative highlights the importance of lived experiences in driving innovative healthcare solutions. For more information, please refer to the FAQs on their website.
Health Care Access & Delivery

Artist Support Grants - Caswell, Rockingham, Stokes, Surry and Yadkin Counties

North Carolina Arts Council
State/Local Government
Caswell County, North Carolina, Rockingham County, North Carolina +3 more
US $500 - US $1,500

About

What are Artist Support Grants?

Artist Support Grants is a program funded by the N.C. Arts Council to provide the opportunity for regional consortia of local arts councils to award project grants to artists in their regions.

Application Information

  • Stokes County Arts Council
  • Primary Contact: Eddy McGree
  • Phone: 336-598-8159
  • Email: stokesarts@gmail.com
  • Web: https://stokesarts.org/
Artist Training & Development

Artist Support Grants - Carteret, Craven, Duplin, Jones, Lenoir, Onslow and Pamlico Counties

North Carolina Arts Council
State/Local Government
Carteret County, North Carolina, Craven County, North Carolina +5 more
US $500 - US $1,000

About

What are Artist Support Grants?

Artist Support Grants is a program funded by the N.C. Arts Council to provide the opportunity for regional consortia of local arts councils to award project grants to artists in their regions.

Application Information

  • Craven Arts Council and Gallery
  • Primary Contact: Jonathan Burger
  • Phone: 252-638-2577
  • Email: director@cravenarts.org
  • Web: https://www.cravenarts.org
Artist Training & Development

Artist Support Grants - Franklin, Granville, Halifax, Northampton, Vance and Warren Counties

North Carolina Arts Council
State/Local Government
Franklin County, North Carolina, Granville County, North Carolina +4 more
US $500 - US $1,000

About

What are Artist Support Grants?

Artist Support Grants is a program funded by the N.C. Arts Council to provide the opportunity for regional consortia of local arts councils to award project grants to artists in their regions.

Application Information

  • Granville Arts
  • Web: https://granvilleartsnc.org
Artist Training & Development

Outcomes Innovative Pharmacy Grant Program - Original Track

Iowa Pharmacy Association
Private
Iowa
Up to US $10,000
The Outcomes Innovative Pharmacy Grant Program supports innovative pharmacy initiatives in Iowa. It offers funding up to $10,000 for projects aiming to enhance pharmacy practices. Eligible applicants include Iowa licensed pharmacists and researchers who are active members of the Iowa Pharmacy Association. The program encourages collaboration and requires a presentation of the grant proposal along with final reports detailing project outcomes and fund distribution.
Pharmacology

FY2027: MassLINKS — Adult Education Virtual School

Massachusetts Department of Elementary and Secondary Education
State/Local Government
Massachusetts
Unspecified amount

FY2027: MassLINKS — Adult Education Virtual School

The purpose of this continuation grant is to support a statewide Adult Education Virtual School (AEVS) system branded as MassLINKS. All ABE and ESOL services must be delivered virtually.

The MassLINKS provider will recruit, intake, orient, enroll, instruct, assess, advise, and offer supportive services/post exit follow up to adult learners who are not served by programs currently funded by ACLS and/or whose need for services are not met by programs currently funded by ACLS.

Priorities:

The MassLINKS provider will:

  • deliver a program design which includes synchronous and asynchronous instruction
  • serve the targeted enrollment of 780 learners (330 — ABE, 450 — ESOL) on a monthly basis encompassing the 16 local workforce development areas
  • assist eligible individuals in attaining a secondary school credential and transition to postsecondary education and training through career pathways
  • assist eligible individuals to become literate and obtain the knowledge and skills necessary for employment and economic self-sufficiency
  • assist individuals who are English language learners— improving their reading, writing, speaking, and comprehensive skills in English including mathematical skills
  • assist eligible individuals who are parents or family members to a) obtain the education and skills that are necessary to become full partners in the educational development of their children and b) result in sustainable improvements in the economic opportunities for their family
  • reduce disparity in education by providing, in collaboration with WIOA partners and others, high-quality adult education programming that provides an inclusive and welcoming environment, rigorous curriculum and instruction, and related learner support services

Funding:

Approximately $3,000,000 available.

This RFP is the governing document for these grant funds.

Funding is contingent upon availability. All dollar amounts listed are estimated/approximate and are subject to change. If more funding becomes available, it will be distributed under the same guidelines that appear in this RFP document

Adult Education

FY27 Registered Teacher Apprenticeship Program: Targeted Implementation Grant

Massachusetts Department of Elementary and Secondary Education
State/Local Government
Massachusetts
Unspecified amount

FY27 Registered Teacher Apprenticeship Program: Targeted Implementation Grant

The Massachusetts Department of Elementary and Secondary Education (DESE) is offering a targeted grant to continue implementation support for a cohort of districts in Year 2 of Registered Teacher Apprenticeship Program implementation. Registered Teacher Apprenticeship Programs (RTAPs) in Massachusetts are innovative pathways into teaching designed to build a diverse and effective teaching workforce that reflects the rich cultural backgrounds of our students. At the heart of RTAP is a commitment to providing equitable opportunities for aspiring educators, particularly those from underrepresented communities, to enter the teaching profession for little to no cost.

RTAP offers a new pathway to earning an Initial license in Massachusetts. RTAP integrates on-the-job training with academic coursework, allowing participants to earn while they learn. This hands-on approach ensures that apprentices gain practical classroom experience under the supervision of experienced educators while simultaneously completing the requirements for Initial licensure.

Funding:

Approximately $1,750,000 is available for this grant.

Funding is contingent upon availability. All dollar amounts listed are estimated/approximate and are subject to change. If more funding becomes available, it will be distributed under the same guidelines that appear in this RFP document.

Teacher Development & Training

Tree Campus Higher Education Program: North Dakota

National Arbor Day Foundation
Private
North Dakota
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, led by the National Arbor Day Foundation, promotes the importance of trees in campus environments. By fostering community forests, this program not only enhances the beauty and livability of college campuses but also addresses critical environmental issues. Schools can gain national recognition by meeting five key standards, thereby encouraging student involvement in tree-related projects while benefiting mental health and reducing energy needs.
Greening & Beautification

Santa Fe Ten Memorial Grant Program

Texas Education Agency
State/Local Government
Galveston County, Texas
Up to US $2,700,000

Santa Fe Ten Memorial Grant Program

The purpose of this grant program is to provide a grant to the Santa Fe Ten Memorial Foundation to assist in the creation of a memorial that remembers and honors those who died, and all individuals impacted on May 18, 2018, by the Santa Fe High School shooting.

Crime Victim Services

PDF Travel Award to Annual CSZ Meeting

Canadian Society of Zoologists
Association/Society
Canada
Up to C $500
The PDF Travel Award to the Annual CSZ Meeting is designed to support post-doctoral fellows in attending the Canadian Society of Zoologists' Annual Meeting. This need-based award offers up to $500 to assist with travel expenses, with a preference for applicants outside Canada. To qualify, candidates must be CSZ members for at least two years and present as first authors at the meeting. The award aims to foster participation and collaboration in zoological research.
Zoology

Tree Campus Higher Education Program: North Carolina

National Arbor Day Foundation
Private
North Carolina
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, led by the National Arbor Day Foundation, encourages colleges to foster green spaces and community forests. By meeting five essential standards, campuses can achieve national recognition, enhancing their environmental impact and providing mental health benefits for students. Participation promotes sustainability, energy efficiency, and student involvement in environmental stewardship. This initiative not only beautifies campuses but also builds pride among students and the wider community, making it a valuable program for educational institutions.
Greening & Beautification

Cheryl A. Young Scholarship

The Dayton Foundation
Private
Montgomery County, Ohio
US $1,000
The Cheryl A. Young Scholarship honors the memory of a dedicated family member and community supporter. It aims to assist graduating seniors from Dayton Public Schools or current students at Sinclair Community College who demonstrate leadership and community service, maintain a minimum 3.0 GPA, and show financial need. This scholarship reflects Cheryl's commitment to education and helping others, ensuring her legacy continues to impact future generations.
Academic Scholarship Programs

Keep Playing the Game Scholarship

The Dayton Foundation
Private
Montgomery County, Ohio
Unspecified amount
The Keep Playing the Game Scholarship, funded by The Dayton Foundation, supports University of Dayton Sport Management alumni pursuing further education or professional development. This initiative encourages alumni to break out of their comfort zones and seek advancement opportunities. Awards can be used for graduate school, training, or approved career-related expenses. The scholarship embodies the spirit of continuous personal growth and aims to empower alumni to achieve their goals and contribute positively to their fields.
Education - Higher Education

CSZ: Conference Travel Grants

Canadian Society of Zoologists
Association/Society
Canada
Unspecified amount
The Canadian Society of Zoologists offers Conference Travel Grants to support students and postdocs presenting at their Annual Meeting. This initiative aims to alleviate travel and lodging expenses for participants, fostering educational and research opportunities in zoology. Eligible candidates must be actively presenting their work, ensuring that the funds are utilized effectively to promote knowledge exchange within the scientific community. The amount of funding is contingent upon available resources and the distance traveled.
Zoology

Adult Protective Services Technology Modernization Grant

Illinois Department on Aging (IDoA)
Federal Government
Illinois
US $1,045 - US $44,639
The Adult Protective Services Technology Modernization Grant provides funding to assist Illinois service providers in upgrading their technology to improve efficiency in serving older adults. Eligible applicants include various government and nonprofit organizations that have previously submitted a letter of intent. The grant supports reimbursement for qualifying technology purchases, excluding large items over $5,000, ensuring agencies can enhance their service delivery capabilities effectively.
Senior Services

Tree Campus Higher Education Program: New York

National Arbor Day Foundation
Private
New York
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, initiated by the Arbor Day Foundation, promotes the integration of trees and green spaces into college campuses. By adhering to five key standards, institutions can achieve national recognition while enhancing the well-being of students and the environment. This program not only fosters community pride but also supports sustainability efforts, making campuses healthier and more beautiful for all. Join the movement to cultivate a greener future through education and active participation.
Greening & Beautification

Bee a Rae of Sunshine Foundation – MaKenzi Rae Cash Memorial Volleyball Scholarship

Community Foundation of Carroll County
Private
United States
US $4,000

Community Foundation of Carroll County

The Community Foundation of Carroll County, Inc. was established in 1994 to ensure financial support for Carroll County not-for-profit organizations. It is governed by a Board of Directors and is a 501c(3) public charity. The Community Foundation of Carroll County is trusted partner for donors and nonprofits. We provide one central place where anyone can create a charitable fund, support what matters most, and leave a legacy of lasting impact.

Scholarships

The Community Foundation of Carroll County supports more than 75 scholarships. These scholarships vary in the amounts they award and cover a wide variety of student interests. Qualifiers range from academic achievements, sports played, and community service performed, to 4-H and FFA involvement. While the majority are for graduating Carroll County high school seniors, there are several for students in college or technical school, and even opportunities for students attending private primary school. 

Bee a Rae of Sunshine Foundation – MaKenzi Rae Cash Memorial Volleyball Scholarship

To empower student-athletes who demonstrate leadership, teamwork, and a passion for uplifting others, celebrating MaKenzi Rae Cash’s spirit of perseverance, kindness, and her advocacy for anti-bullying both on and off the court.

Education - Higher Education

Danele Shipley Memorial Scholarship Fund

Community Foundation of Carroll County
Private
United States
Unspecified amount

The Community Foundation of Carroll County supports nearly 70 academic, sports, special circumstances, and 4-H scholarships. Search scholarships by name, or sort by application type.

Danele Shipley Memorial Scholarship Fund

The Danele Shipley Scholarship Award Fund will provide financial assistance to a number of students from Carroll County to be determined based on the amount of money available in accordance with the terms of this agreement. The student must have shown outstanding citizenship traits and have been involved in student service activities and extra-curricular activities during his or her high school career.

Education - Higher Education

Westminster Pride Scholarship

Community Foundation of Carroll County
Private
United States
US $2,000

Community Foundation of Carroll County

The Community Foundation of Carroll County, Inc. was established in 1994 to ensure financial support for Carroll County not-for-profit organizations. It is governed by a Board of Directors and is a 501c(3) public charity. The Community Foundation of Carroll County is trusted partner for donors and nonprofits. We provide one central place where anyone can create a charitable fund, support what matters most, and leave a legacy of lasting impact.

Scholarships

The Community Foundation of Carroll County supports more than 75 scholarships. These scholarships vary in the amounts they award and cover a wide variety of student interests. Qualifiers range from academic achievements, sports played, and community service performed, to 4-H and FFA involvement. While the majority are for graduating Carroll County high school seniors, there are several for students in college or technical school, and even opportunities for students attending private primary school. 

Westminster Pride Scholarship

The Westminster Pride Scholarship aims to provide some assistance to students of the LGBTQ+ community and student allies in furthering their education beyond high school.

Education - Higher Education

James P. Jackson Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount
The James P. Jackson Scholarship, provided by the Community Foundation for Muskegon County, aims to support graduating seniors from Muskegon County High Schools pursuing an Accounting degree. Established by the Jackson family in memory of James P. Jackson, this scholarship reflects a commitment to empowering students to achieve their educational goals. The Community Foundation manages an extensive scholarship program, offering over $1 million annually to help students realize their dreams and contribute to the community.
Education - Higher Education

Jackson-Merkey Contractors Educational Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Jackson-Merkey Contractors Educational Scholarship

This scholarship has been made possible by the generosity of Steve Jackson and Gary Merkey, who established the Jackson-Merkey Contractors Educational Scholarship of the Community Foundation for Muskegon County. Steve Jackson and Gary Merkey have been friends since high school and business partners for many years now. They were really excited to start this find and wish they had thought of it long ago. This scholarship will benefit Muskegon County high school graduates working toward any degree but with a preference given to students pursuing a degree in Civil Engineering or Constuction Management.

Education - Higher Education

Hispanic Community Services Coaltion Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Hispanic Community Services Coaltion Scholarship

This scholarship has been made possible by the generosity of the Hispanic Community Services Coalition, who established the Hispanic Community Services Coalition Scholarship of the Community Foundation for Muskegon County. The Mission of the Hispanic Services Coalition of Muskegon County is to serve the Hispanic community through education, health information and services as an instrument in improving their quality of life. HCSC promotes the Hispanic culture within Muskegon County and acts as a cultural reference. This scholarship is for a Hispanic or Latino graduating seniors who are residents of and/or attend high school in Muskegon County.

Education - Higher Education

Communities Outreach Programme

Islamic Development Bank
Corporate
Andorra, Angola +138 more
Unspecified amount
The Communities Outreach Programme by the Islamic Development Bank aims to enhance the socio-economic development of Muslim minority communities in non-member countries. Established in 1981, it focuses on education, health, and capacity building to empower these communities. The programme supports initiatives that foster entrepreneurship, women's empowerment, and youth development, ensuring inclusive growth. By addressing the needs of vulnerable populations, it strives to improve living conditions and promote productivity, ultimately contributing to sustainable development in diverse regions.
Islam & Islamic Culture

Tree Campus Higher Education Program: Indiana

National Arbor Day Foundation
Private
Indiana
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, initiated by the Arbor Day Foundation, encourages colleges and universities to enhance their green spaces, benefiting both the environment and student well-being. By meeting five standards, participating institutions can gain national recognition for their commitment to tree care and sustainability. This initiative not only fosters a healthier campus but also engages students in environmental stewardship, making a positive impact on their communities. Join to celebrate the importance of trees in our lives.
Greening & Beautification

American Association for Anatomy: International Travel Award

American Association For Anatomy
Private
Bernalillo County, New Mexico
US $2,000
The American Association for Anatomy offers the International Travel Award to support members at international institutions in attending and presenting at the Annual Meeting. This needs-based award provides three grants of $2,000 each, reimbursed post-meeting. Applicants must be current members and submit an abstract for the meeting to be eligible. Note that these travel funds cannot be combined with other awards. For further details and submission guidelines, visit their official website.
Anatomy

Tree Campus Higher Education Program: Illinois

National Arbor Day Foundation
Private
Illinois
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, initiated by the Arbor Day Foundation, empowers colleges and universities to enhance their campus environments through tree planting and maintenance. This program promotes sustainability and community involvement, providing frameworks for institutions to achieve national recognition while fostering student engagement in environmental stewardship. Participating schools benefit from improved mental health, energy efficiency, and a sense of pride in their green initiatives, contributing positively to both student life and the broader community.
Greening & Beautification

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.