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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

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$8.25B

Total funding

$6K

Median grant

33,000+ grants
$8.25B total
$6K median

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32,600 Results based on applied filters

Oklahoma- Urban and Community Forestry Grants

Oklahoma Department of Agriculture, Food and Forestry
State/Local Government
Oklahoma
US $5,000 - US $50,000
The Oklahoma Urban and Community Forestry Grants, offered by the Oklahoma Department of Agriculture, Food and Forestry, aim to enhance urban forestry initiatives across the state. These grants, ranging from $1,000 to $10,000, support projects such as public tree inventories, management plans, and educational programs. Organizations are encouraged to propose creative solutions that foster community engagement and sustainable forest management, ultimately improving local green spaces and promoting citizen involvement.
Forestry Greening & Beautification Urban Planning

Teams to Promote Aging in Place in OMH Supportive Housing (TPAP) Grant

New York State Office of Mental Health
State/Local Government
Allegany County, New York, Broome County, New York +42 more
US $300,000 - US $1,500,000

Teams to Promote Aging in Place in OMH Supportive Housing (TPAP) 

Request for Proposals

The purpose of “Teams to Promote Aging in Place in OMH Supportive Housing or TPAP” Geriatric Demonstration Project is to facilitate supportive housing residents aging in place based on their priorities and preferences who are age 55 years and older, as well as residents younger than 55 years living with complex medical conditions that necessitate homecare. Older adults living in OMH supportive housing are at risk of losing community tenure due to emerging unmet care coordination, cross service system navigation, and homecare needs compounded by lack of connection to social determinants of health (SDOH) resources, and community and natural supports. Grant funding will support an enhanced home care rate, provision of at least one paid peer professional, and enhanced care coordination with the local office for aging and community partners that addresses social determinants of health and social engagement needs. OMH supportive housing residents identified as at risk for losing community tenure will be supported by an interdisciplinary care team of (1) an OMH supportive housing case manager, (2) a local office for aging case manager, (3) a homecare professional, and (4) at least one mental health or substance use/gambling peer professional who will collaborate with the residents to identify outstanding service and social needs. This will build a person-centered, holistic plan that is based on the older adult’s priorities and preferences for aging in place. A peer professional in this RFP is defined as a person certified, or provisionally certified, as a mental health Peer Specialist through the New York Peer Specialist Certification Board or a person certified, or provisionally certified, as a substance use/gambling Recovery Peer Advocate through the New York Certification Board. Grantees will also be required to collaborate with community-based organizations across service systems, including mental health, aging, substance use, and gambling harms, that also address social determinants of health and social engagement needs, such as, but not limited to, Social Care Networks, Rural Health Networks, Cornell Cooperative Extension, Older Adult Rural Support Program, Regional Economic Development Councils, or Downtown Revitalization Initiatives. This may include projects focused on community inclusion, the Dwyer Veterans Peer-to-Peer Support Program, club houses, OASAS and OMH recovery centers, older adult centers, faith-based, civic, arts, cultural organizations, etc. To foster sharing of best practices in meeting the holistic needs of OMH supportive housing residents, grantees and their partners will participate in virtual and in-person learning collaboratives that include crossdisciplinary training curriculum consisting of trainings chosen in consultation with the chosen grantees and the Geriatric Interagency Mental Health Substance Use Disorder Planning Council and the Master Plan for Aging advisory groups.

Wrap around funding will be available to provide services and goods not covered through existing reimbursement channels that support aging in place in OMH supportive housing. Examples include, but are not limited to, non-medical transportation, memberships to community groups and/or gyms, continuing education, supplies to support personal interests and hobbies, large print calendars, pill containers, and mobility aids. Wrap-around funding can also be used to provide technological support based on the residents’ needs and preferences. Examples include equipment (laptops, computers, personal devices, and/or internet access), online communities and devices to support engagement (Virtual Senior Centers, GetSetUp, Discover Live interactive virtual tours, animatronic pets, and online support through self-help and peer support groups), and technology literacy classes (for email, video chats with friends, children, grandchildren, etc., banking, patient portals, and education on fraud protection) are additional supports to help people use technology to age in place.

This RFP can be used to expand or enhance existing aging programs in OMH supportive housing or can be used to develop a new program that meets all the program requirements. OMH CR-SROs awarded the “Aging in Place Pilot” grant MH253015 may also apply for this grant for their supportive housing programs.

All types of proposals will be evaluated using the same criteria and applicants must identify the geographic designation they will serve, rural or non-rural. Rural counties in NYS are listed in the table below.

Aging / Gerontology Supportive Housing & Shelters Health Disparities & Social Determinants of Health +2 more

Community Action Grants - Environment

Silicon Valley Community Foundation
Private
San Mateo County, California, Santa Clara County, California
Unspecified amount
The Community Action Grants - Environment program by the Silicon Valley Community Foundation aims to support organizations addressing environmental disparities in San Mateo and Santa Clara counties. It prioritizes funding for groups focused on racial justice and community engagement, especially those with budgets under $3 million. The initiative encourages innovative solutions to climate challenges while fostering community involvement in shaping environmental policies. This grant opportunity underscores the importance of creating equitable, sustainable environments for underserved populations.
Environmental Justice & Advocacy Racial / Ethnic Justice & Rights Climate Change Resilience & Equity

Wisconsin Forest Landowner Grant Program

Wisconsin Department of Natural Resources
State/Local Government
Wisconsin
Unspecified amount

Wisconsin Forest Landowner Grant Program

The Wisconsin Forest Landowner Grant Program (WFLGP) is a cost-share program offered by the Wisconsin Department of Natural Resources (DNR). It is designed to assist woodland owners in protecting and enhancing their woodlands. This program reimburses woodland owners up to 50% of the cost of eligible practices.

Forestry Environmental Conservation

Sanitary & Storm Sewer Funding

South Dakota Department of Agriculture & Natural Resources
State/Local Government
South Dakota
Unspecified amount
The Sanitary & Storm Sewer Funding program supports projects aimed at improving wastewater treatment and storm water management in South Dakota. Grants and low-interest loans are available, with eligibility contingent on inclusion in the State Water Facilities Plan. Additional subsidies may be granted based on established water rates and economic development needs. Applications are accepted quarterly, and projects must meet specific requirements to qualify for funding.
Sanitation & Clean Drinking Water Water Resource Management

Edna E. Harrell Community Children’s Fund Grant

The Oregon Community Foundation
Private
Baker County, Oregon
US $1,000 - US $5,000
The Edna E. Harrell Community Children’s Fund Grant, managed by The Oregon Community Foundation, supports programs enhancing the lives of underserved youth in Baker County and North Powder. Established in 2014, it provides funding for various enrichment activities, including summer camps, after-school programs, and arts initiatives. Eligible applicants include nonprofit organizations, churches, and schools, ensuring that children from financially constrained families have access to vital development opportunities.
Child Welfare Services Youth Services Summer Camps +4 more

Small Community Planning Grant

South Dakota Department of Agriculture & Natural Resources
State/Local Government
South Dakota
US $8,000 - US $10,000
The Small Community Planning Grant Program offers financial assistance to small communities for water and wastewater infrastructure management. Eligible entities can receive up to $10,000 for engineering studies, covering 80% of costs. The program aims to help communities develop necessary engineering reports for their projects. To qualify, communities must serve populations of 2,500 or fewer and meet specific eligibility criteria. This proactive approach ensures that essential infrastructure needs are addressed effectively.
Sanitation & Clean Drinking Water Water Resource Management

F26AS00030 Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program

US Department of the Interior: Fish and Wildlife Service (FWS)
Federal Government
American Samoa, Guam +4 more
US $10,000 - US $14,162,000
The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.
Wildlife Management Land / Habitat Conservation Wildlife Health

Water Quality Improvement Project (WQIP) Program

New York State Department of Environmental Conservation (DEC)
State/Local Government
New York
Unspecified amount

Water Quality Improvement Project (WQIP) Program

The Water Quality Improvement Project (WQIP) program is a competitive, statewide reimbursement grant program that funds projects that directly improve water quality or habitat, promote flood risk reduction, restoration, and enhanced flood and climate resiliency, or protect a drinking water source.

Sanitation & Clean Drinking Water Water Resource Management

Primary Instruction by Volunteers (PIV) Grant

Massachusetts Department of Elementary and Secondary Education
State/Local Government
Massachusetts
US $500,000 - US $550,000
The Primary Instruction by Volunteers Grant aims to enhance adult basic education services for eligible adults unable to enroll in traditional classes. With a funding pool of approximately $500,000, the program targets around 1,000 adult learners annually, focusing on effective one-on-one tutoring by trained volunteers. Priorities include curriculum alignment with educational standards, building college and career readiness skills, and ensuring compliance with funding regulations. This initiative is designed to provide vital educational opportunities and support for adult learners across the Commonwealth.
Adult Education Tutoring & Mentoring English for Speakers of Other Languages (ESOL) Education +2 more

McKinney-Vento Competitive Grant Program (NY)

New York State Education Department
State/Local Government
New York
Up to US $2,500,000
The McKinney-Vento Competitive Grant Program in New York supports educational initiatives for homeless children and youth, ensuring they have equal access to quality education. Funded by the New York State Education Department, the program allocates substantial financial resources to local educational agencies based on the number of identified homeless students. This grant is pivotal in providing essential services like tutoring, health care, and transportation, ultimately promoting academic success and stability for vulnerable populations.
Homelessness Services Academic Success & Enrichment Basic Human Needs +3 more

Transition Readiness Grants

Wisconsin Department of Public Instruction
State/Local Government
Wisconsin
US $25,000 - US $100,000
The Transition Readiness Grants program, established under 2017 Act 59 with $1.5 million in funding, aims to help Wisconsin students with disabilities transition to competitive work and post-secondary education. Since its inception in FY 2019, it has received over 130 applications totaling more than $9 million. Eligible school districts can apply for FY 24 funding to support evidence-based transition practices, including transportation options, competitive employment training programs, and post-secondary supports.
Teacher Development & Training Children With Disabilities Special Needs Education +2 more

NJ Women and Minority Veterans in Construction Trades Grant Program

New Jersey Department of Labor and Workforce Development
State/Local Government
New Jersey
Up to US $1,500,000
The NJ Women and Minority Veterans in Construction Trades Grant Program aims to eliminate economic barriers for women and minority veterans by providing essential training and support for employment in construction trades. This initiative connects military members with quality career opportunities, ensuring they receive the skills necessary for success in registered apprenticeship programs and other industry occupations, ultimately enhancing New Jersey's workforce and economy.
Minority Services Military & Veterans Services Women & Girl Services +3 more

Open Call Grant: Adult Learning

Patterson Family Foundation
Private
Allen County, Kansas, Anderson County, Kansas +88 more
Unspecified amount

Patterson Family Foundation

The Patterson Family Foundation was established to reinvest in rural communities and cultivate values of education and hard work for current and future generations. Currently, the Foundation is led by the adult children of the Patterson Family.

The Patterson Family Foundation, based in Kansas City, Missouri, is a family-led foundation that extends the legacy of Neal and Jeanne Patterson. The Foundation’s mission, “Working together to help rural communities thrive,” is carried forward through strategic grantmaking and other collaborative initiatives that serve rural counties across Kansas and western Missouri. 

Where We Serve

We are geographically focused on assisting Kansas and western Missouri counties with fewer than 50,000 residents.

Our impact is realized through four interconnected priorities:

Economic Opportunity

  • Our vision: Rural communities have resilient economies that offer diverse and stable career opportunities for all residents.
  • We are committed to keeping rural economies strong by helping grow and retain great talent, attracting former and new residents, and investing in opportunities that strengthen and diversify local and regional economies

Education

  • Our vision: All students receive a high-quality education that prepares them for future success.
  • A strong education system is at the heart of a thriving community, and we’re working alongside educators, families, and local leaders to help it grow. This means supporting and developing exceptional teachers, providing students with opportunities to develop skills and experience, and creating more hands-on learning opportunities that prepare students for the future.

Healthcare

  • Our vision: Communities have access to high-quality healthcare services, leading to improved health outcomes and increased well-being for all residents.
  • Access to quality healthcare is essential for keeping rural communities strong. We work to expand the healthcare workforce, improve access to essential services, and empower all rural residents to lead long, healthy lives.

Community Engagement

  • Our vision: Residents are actively engaged in decision-making process, contribute to community development, and have a strong sense of belonging and purpose.
  • Strong communities are built through local leadership, volunteerism, and collaboration. We work alongside communities to drive grassroots engagement and empower multi-generational leaders. Through regional partnerships and strong community foundations, we help communities deepen relationships, expand opportunities, and steward local resources for future generations.

Open Call Grants

Patterson Family Foundation’s Open Call Grants are publicly announced and submitted through the Grants Portal. Applications are reviewed using criteria aligned with the Foundation’s priorities, including community impact, feasibility, sustainability, and readiness to implement the proposed work in the Kansas or western Missouri rural community. 

Open Call Grant: Adult Learning

This opportunity supports adult learners in building literacy, workforce readiness, and lifelong learning skills. Funding helps reduce barriers to participation and expands equitable access to evidence-based education that prepares adults for meaningful employment, civic engagement, and personal advancement. Projects should strengthen community-based programs, support innovation, and align adult learning with local workforce needs, with priority given to organizations in our rural catchment area or partnering with local employers. Applicants should plan to report on learner participation, skills or credentials gained, employment or career advancements, and partnerships that connect adult learners to local opportunities. 

Eligible uses of funds include:  

  • Funding for new instructors and staff training 
  • Instructional materials 
  • Technology and digital learning tools 
  • Outreach and recruitment 
  • Support services that reduce participation barriers 
  • Program evaluation and data collection   
Workforce Preparation & Job Readiness Adult Education Literacy +2 more

SHIFT 3.3 Rural EMS Request for Grant Applications

Utah Department of Health and Human Services
State/Local Government
Utah
US $12,500,000

About DHHS

Vision

All Utahns have fair and equitable opportunities to live safe and healthy lives.

Mission

The Utah Department of Health and Human Services will support and serve all individuals and communities throughout Utah. It will do so through effective policy and the operations of an effective and efficient seamless system of services and programs that is centered around the individuals and communities the department serves.

SHIFT 3.3 Rural EMS Request for Grant Applications

Project overview:

The Sustaining Health Infrastructure for Transformation (SHIFT) initiative is designed to transform preventive care. SHIFT focuses on enhancing local service delivery and modernizing infrastructure. It supports capital improvements, expands services like community paramedicine, and establishes integrated rural health provider networks to build a more resilient and interconnected healthcare system.

This RFGA will provide funding to rural and Tribal EMS communities to strengthen emergency medical services and workforce capacity by expanding training access, improving communications, facilitating data exchange, and enhancing community paramedicine capabilities.

Applicants must align their proposal with one or more of the following programs:

Indigenous Health Systems Community Health Education Preventative Healthcare +4 more

Mary Kay Ash Foundation: Cancer Research Grant

Mary Kay Ash Foundation (United States)
Corporate
United States
Up to US $100,000

Mary Kay Ash Foundation

Guided by Mary Kay Ash’s dream to enrich the lives of women everywhere, the Mary Kay Ash Foundation® raises and distributes funds to invest in breakthrough cancer research and clinical trials to find a cure for women-related cancers and ending domestic violence.

Since 1996, the Mary Kay Ash Foundation®, a 501(c)3 organization, has contributed more than $100 million to organizations aligned with its two-fold mission. In addition, the Foundation supports awareness initiatives, community outreach programs, and advocates for legislation to ensure women are healthy and safe. Through our global charitable foundations in Brazil, Canada, China and the United States, we are collectively making a deeper impact on the lives of women around the world.

Mary Kay Ash Foundation: Cancer Research Grant

The Mary Kay Ash Foundation is a non-profit public foundation, which focuses on funding research for innovative grants for translational research of cancers affecting women (ovarian, uterine, breast, endometrial or cervical cancer among others). Translational research is broadly defined as research that will provide a scientific link between laboratory research and the clinic. Ultimately, such research would lead to improvement in diagnosis, prognosis, prevention, or treatment of the cancer. Each year the Foundation extends invitations to NCI designated cancer institutes and accredited medical schools to apply. Only one application is accepted per institution.

Grant proposals are reviewed by a Scientific Research Review Committee comprised of notable members of the American medical and scientific community. Grants are awarded up to $100,000 (combined direct and indirect costs) for a two-year period. The Foundation anticipates funding between 10 and 15 grants annually. 

Women's Health Breast Cancer Gynecological Cancers

Playground Communication Boards Program

The Doug Flutie, Jr. Foundation for Autism
Private
Massachusetts
Unspecified amount

The Doug Flutie, Jr. Foundation for Autism

Dougie Jr. was diagnosed with childhood disintegrative disorder (CDD), a very rare autism spectrum disorder, when he was three years old. Dougie was typically developing until he started to lose his language, motor and social skills at age three. At the time, there were no services offered for people and families with autism. Doug and Laurie started the Doug Flutie Jr. Foundation for Autism to help other people and families with autism have access to the same opportunities, therapies and programs to live life to the fullest.

Our mission is to help people and families with autism live life to the fullest. Our Vision is focused in a world where people with autism lead productive lives where they are included, respected, and actively engaged in their communities.

Playground Communication Boards Program

Rooted in the belief that every voice matters, our playground communication board uses images and symbols to bridge gaps in communication. Visual aids support a wide range of learners, including verbal, neurotypical peers, and promote inclusion of people with differing abilities. Our mission is to ensure everyone, regardless of their communication abilities, can express their thoughts, needs, and feelings; fostering a truly inclusive and engaging community.

We are excited to announce that grant applications are now open to playgrounds across Massachusetts as part of our vision: One Board in Every Town and City. Applications will be reviewed on a rolling basis, and applicants will be notified of their status within 30 days of submission.

Autism Playgrounds Speech-Language Learning & Disorders

CFSLC: Women’s Giving Alliance of South Lake

Community Foundation of South Lake County
Private
Lake County, Florida
Unspecified amount
The Women’s Giving Alliance of South Lake, part of the Community Foundation of South Lake County, aims to inspire women to become strategic philanthropists. This initiative focuses on improving the lives of women and children in South Lake County through innovative solutions and measurable impacts. Local nonprofits are encouraged to apply for grants that will facilitate systemic change and address critical needs within the community. This program seeks to create a lasting positive influence on those served.
Women & Girl Services Youth Services Child Welfare Services +3 more

Nonpoint Source Pollution Control Grant

Kentucky Energy and Environment Cabinet
State/Local Government
Kentucky
Unspecified amount
The Nonpoint Source Pollution Control Grant, established under the Clean Water Act, aims to reduce nonpoint source pollution through funding innovative best management practices (BMPs), educational programs, and the development and implementation of Watershed Based Plans. The Kentucky Energy and Environment Cabinet administers this grant, providing up to 60% of project costs, with a required 40% nonfederal match, fostering sustainable environmental practices across the state.
Water Resource Management Environmental Contamination & Pollution

Section 319(h) – NPS Pollution Control Financial Assistance Program - Watershed-Based Plan Implementation and Other Activities NOFO

Illinois Environmental Protection Agency
State/Local Government
Illinois
US $50,000 - US $1,500,000
The Illinois Environmental Protection Agency (Illinois EPA) is inviting proposals for projects aimed at controlling nonpoint source (NPS) pollution, which significantly impacts water quality in Illinois. Funded by federal resources through Section 319(h) of the Clean Water Act, the program seeks to address the over 60% of water pollution traced to NPS. Projects should prioritize the restoration of affected water bodies as outlined in the Integrated Water Quality Report and Section 303d List.
Water Resource Management Environmental Contamination & Pollution

Facility Planning Grants

Idaho Department of Environmental Quality (IDEQ)
State/Local Government
Idaho
US $45,000 - US $65,000
The Facility Planning Grants are designed to assist eligible wastewater and drinking water systems in Idaho by providing financial support for developing facility plans. These grants cover up to 50% of eligible planning costs, with maximum amounts historically set at $45,000 for drinking water and $65,000 for wastewater projects. Interested systems must submit a letter of interest annually between October and January to be considered for funding.
Sanitation & Clean Drinking Water Water Resource Management

The Go RED! (Reduce Emissions from Diesels) Program

Arkansas Department of Energy and Environment
State/Local Government
Arkansas
Unspecified amount

Program Summary

The Reduce Emissions from Diesels (Go RED!) Program is a competitive funding assistance opportunity administered by the Department of Energy and Environment (E&E), Division of Environmental Quality (DEQ). The program is funded by the U.S. Environmental Protection Agency (EPA) under the Diesel Emissions Reduction Act (DERA). The Go RED! Program provides funding assistance for projects that reduce diesel emissions from heavy-duty highway trucks (Gross Vehicle Weight Rating [GVWR] Classes 5–8), buses, marine engines, locomotives, and nonroad engines.

Carbon / Greenhouse Gas Reduction Vehicle Restoration

Women's Fund of Central New York

Central New York Community Foundation Inc
Private
Cayuga County, New York, Cortland County, New York +3 more
Up to US $5,000
The Women's Fund of Central New York, established in 1998, empowers women and girls through grants and initiatives, promoting their advancement and full participation in the community. With a commitment to diversity and inclusion, the fund supports innovative projects that address key challenges faced by women and girls in Central New York. By fostering collaboration and community engagement, the Women's Fund aims to create a stronger, more equitable society for all.
Women's Health Women & Girl Services Children’s Mental Health +2 more

Early-career Raptor Researcher Travel Grants

Raptor Research Foundation
Private
Countries
US $700

About

Raptor Research Foundation

The Raptor Research Foundation (RRF) is the world’s largest professional society for raptor researchers and conservationists. Founded in 1966 as a non-profit organization, our primary goal is the accumulation and dissemination of scientific information about raptors. The Foundation organizes annual scientific conferences and provides competitive grants and awards for researchers and conservationists. The Foundation also provides support and networking opportunities for students and early career raptor researchers.

Early-career Raptor Researcher Travel Grants

The Award:

The selection committee must receive all application materials by the deadline for regular abstracts. That date is included in the announcement of RRF’s annual meeting sent each year to the membership.

  • $700.
  • The award will also include a free 1-year membership to RRF. 

up to three.

Ornithology Ornithological Conservation

Tom Cade Conservation Award

Raptor Research Foundation
Private
Countries
Unspecified amount

About

Raptor Research Foundation

The Raptor Research Foundation (RRF) is the world’s largest professional society for raptor researchers and conservationists. Founded in 1966 as a non-profit organization, our primary goal is the accumulation and dissemination of scientific information about raptors. The Foundation organizes annual scientific conferences and provides competitive grants and awards for researchers and conservationists. The Foundation also provides support and networking opportunities for students and early career raptor researchers.

Tom Cade Conservation Award

The Award:

The Tom Cade Conservation Award is the Raptor Research Foundation’s premiere conservation award. This non-monetary award recognizes an individual who has made significant advances in or exceptional contributions to the conservation of raptors. The award’s scope includes all aspects of conservation science and practice pertaining to raptors, including: implementing population restoration programs; advances in captive propagation and reintroduction techniques; identifying conservation biology problems and solutions; raptor biodiversity studies; and studies of rare, threatened, and endangered species. Nominations will open in the spring. Recipients will be announced at the annual meeting.

About Tom Cade:

Tom Cade was an icon and hero to us all. His passion for falcons knew no bounds. One of the founders of the Raptor Research Foundation, he was the driving force behind the reintroduction of the Peregrine Falcon east of the Mississippi and across much of its North American range. The Peregrine Fund, which he created with the recovery of a single endangered species—the Peregrine Falcon—as its goal, has grown into a conservation organization with a worldwide reach and global impact. 

Ornithological Conservation Ornithology

ECASU Community Awareness Partnerships

Delaware Division of Substance Abuse and Mental Health (DSAMH)
State/Local Government
Delaware
Unspecified amount

Delaware Division of Substance Abuse and Mental Health

The Delaware Division of Substance Abuse and Mental Health (DSAMH) recognizes the need to leverage local community expertise to reach and impact the wide array of communities that continue to be impacted by the opioid overdose crisis. DSAMH also acknowledges that not all communities have been or are impacted equally. Although there have been recent improvements in drug overdose deaths, significant work remains. DSAMH is committed to offering multiple ways to partner with communities to prevent overdose, reduce the impact of opioid and stimulant use disorders, and improve access to prevention, treatment, and recovery services across Delaware.

ECASU Community Awareness Partnerships

Through the federal State Opioid Response (SOR) Grant, the Engaging Communities in Addressing Substance Use (ECASU) initiative offers three opportunities for organizations and community leaders working to address OUD/STUD in Delaware:

  • Messaging Campaigns (ECASU-MC)
  • Mini-Grants (ECASU-MG)
  • Community Awareness Partnerships (ECASU-CP)
    • The ECASU Community Awareness Partnerships (ECASU-CP) provide technical assistance to community-based, grassroots, advocacy, faith-based organizations, community coalitions, community leaders, and treatment providers (collectively referred to as Community Partners) to directly engage members of the community to educate, increase awareness, and provide resources for OUD/STUD. These strategies can include, but are not limited to, in-person events, educational sessions, social media strategies, video campaigns, and listening sessions. Below are the focus areas of DSAMH’s current campaign strategies, which require a focus on opioid and stimulant use, that can be supported by DSAMH and its technical assistance vendors for partners to refine and implement within their own communities.
      • Reduced stigma toward persons with OUD/STUD
      • Promoting awareness of and access to OUD/STUD treatment and recovery services
      • Reducing stigma toward medications for opioid use disorders, such as methadone and buprenorphine
      • Promoting access to naloxone/Narcan
      • Increasing awareness and knowledge of existing resources among local communities 
Addiction & Substance Use Disorders Drug Use Disorder Community Health Education

Greater Lake Superior Foundation Grant Program

The Greater Lake Superior Foundation
Private
Canada, Michigan +2 more
US $2,000
The Greater Lake Superior Foundation Grant Program provides $2000 grants annually to support graduate research on Coaster Brook Trout in Lake Superior and its tributaries. Eligible applicants must be graduate students from accredited universities in Michigan, Minnesota, Ontario, or Wisconsin, focusing on Fisheries Management, Limnology, Ecology, or Biology. Research topics include habitat requirements, migratory behavior, and management activities. Recipients must submit a project summary for publication on the GLSF website.
Ecology Ichthyology (Fish) Limnology +1 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.