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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,545 Results based on applied filters

Julius Glickman Fellowship in Public Interest Law

William Wayne Justice Center for Public Interest Law
Private
Texas
Up to US $75,000
The Julius Glickman Fellowship in Public Interest Law, supported by the William Wayne Justice Center, aims to enhance access to justice by funding an exceptional Texas Law graduate or judicial clerk to work with a public interest organization. This one-year, full-time fellowship is designed to empower new attorneys to provide vital legal services to underrepresented individuals or groups, focusing on civil legal services, and fostering a commitment to public interest lawyering.
Law Legal Services

Rhode Island Council For The Humanities: THRIVE Program

Rhode Island Council For The Humanities
Private
Rhode Island
Up to US $5,000
The Rhode Island Council for the Humanities is launching the FY26 THRIVE Grant Program, which offers 20 grants of $5,000 each to small cultural heritage organizations and local historical societies in Rhode Island. This program aims to support organizations that enhance community engagement and preserve local history. Eligible applicants must be nonprofit entities located in Rhode Island, with a focus on serving local residents. Applications will be assessed based on eligibility and alignment with funding priorities.
Community Services Historic Preservation

Collaborative Program Grant for Multidisciplinary Teams

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $900,000
The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.
Science Biology Health & Medicine

Bloomfield Greater Together Community Fund Grant

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $500 - US $10,000
The Bloomfield Greater Together Community Fund Grant, established by the Hartford Foundation for Public Giving, aims to empower local organizations by providing financial support for projects that benefit Bloomfield residents. Eligible organizations must be classified as 501c3 or have a fiscal sponsor. The fund seeks to foster community ownership, encourage civic engagement, and strengthen the Hartford Foundation's presence in the town. This initiative is vital for building inclusive and vibrant communities in Greater Hartford.
Civic Engagement & Education Community Services

SSRC-JF Next Gen Japan Postdoctoral Fellowship

Social Science Research Council
Private
United States
Up to US $60,000

Mission

The Social Science Research Council (SSRC) is an independent, international, nonprofit organization founded in 1923. The Council fosters innovative research, nurtures new generations of social scientists, deepens how inquiry is practiced within and across disciplines, and mobilizes necessary knowledge on important public issues.

SSRC-JF Next Gen Japan Postdoctoral Fellowship

The SSRC-JF Next Generation Japan Studies Development Program invites US colleges and universities to apply for grants to support postdoctoral fellowships. This program provides grants of up to $60,000 as partial support for the hiring of recent PhD students specializing in Japan to both teach and conduct research on Japan, within any social science or humanities discipline, at the institution for one academic year. This program is supported by the Japan Foundation.

Background

The Next Gen Japan Postdoctoral Fellowship provides an opportunity for fellows to conduct essential research early in their careers while concurrently gaining valuable teaching experience and a greater understanding of the demands of professorship through this bridge from graduate school to tenure track positions.

Further, this fellowship provides host institutions with the means to enrich the offering of Japan-related courses, in particular, while enhancing the depth of a broad array of disciplines through the use of Japan in comparison or as a case study.

Priorities

  • Priority is given to applications from colleges and universities located in the US South and Midwest.
  • Priority is given to institutions planning Postdoctoral Fellow course assignments that allow for the enrollment of students from a variety of disciplines ranging from the humanities and social sciences to the natural sciences.

Humanities & Social Science Cross-Cultural Understanding & Exchanges

The Greater Mount Hope Community Fund

Beckley Area Foundation
Private
Fayette County, West Virginia
Up to US $41,000
The Greater Mount Hope Community Fund, initiated in 2007 by dedicated citizens, aims to revitalize the historic Mt. Hope area through community-driven programs and fundraising. Managed by the Beckley Area Foundation, this endowment supports local initiatives that enhance the quality of life for residents. With a commitment to sustainable giving, the fund has engaged in various successful activities, including selling local calendars and organizing fundraising campaigns, ensuring a lasting impact on the community.
Community Services Economic Services & Development

Farmington Greater Together Community Fund Grant

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $500 - US $5,000
The Farmington Greater Together Community Fund, established by the Hartford Foundation for Public Giving, offers up to $7,500 for projects that promote civic engagement and community ownership. This fund supports organizations classified as 501(c)(3) or those using a fiscal agent. Eligible projects must benefit all residents without discrimination and may include broader community initiatives by religious organizations. A final report is required upon project completion.
Community Services Civic Engagement & Education

Medical Scientist Training Program (MSTP)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.
Science Medical Education & Professional Training

Technology Initiative Grant

Legal Services Corporation
Private
United States
More than US $40,000
The Technology Initiative Grant (TIG) program by the Legal Services Corporation aims to enhance legal services for low-income populations through innovative technology. It encourages partnerships with justice organizations and supports projects that improve service delivery and efficiency. With a minimum funding request of $40,000, the program seeks to implement new strategies or enhance existing technologies to provide high-quality legal assistance. The initiative fosters replication of successful methodologies from previous projects and other sectors.
Legal Services Emerging Technology Development

Centers of Biomedical Research Excellence: Development Phase (COBRE-D)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
Alaska, Arkansas +22 more
Up to US $400,000
The Centers of Biomedical Research Excellence: Development Phase (COBRE-D) program aims to enhance biomedical research capacity in IDeA states, which historically receive low NIH funding. By providing critical support for early-career investigators and essential infrastructure, COBRE-D facilitates a long-term vision for institutions. This initiative not only supplements start-up packages for new hires but also establishes research facilities and improves administrative services, paving the way for less-resourced institutions to transition into the COBRE E/S program.
Science Biology Health & Medicine

James W. Cooper Fellows

Connecticut Bar Foundation
Private
Connecticut
Unspecified amount
The James W. Cooper Fellows program, established by the Connecticut Bar Foundation, invites nominations for outstanding Connecticut lawyers, judges, and law educators to enhance understanding of the legal profession and justice administration. Selected nominees commit to a $2,500 pledge over ten years. The program aims to improve civil justice through various grants and initiatives, reinforcing the foundation's mission of equitable legal access and education in Connecticut.
Law Legal Services

Jack and Jill of America Foundation Scholarship

United Negro College Fund Inc
Private
United States
Up to US $2,500

Jack and Jill of America Foundation Scholarship

The Jack and Jill of America Foundation Scholarship will provide need-based scholarships of up to $2,500 to service-oriented college freshmen who have completed a minimum of 60 hours of community service within the last 12 months. Awards will be issued in the 2025-2026 academic year, and may be renewed annually through the senior year.

The Jack and Jill of America Foundation is committed to the positive development of youth and future leaders. Through providing programs focused on financial literacy, education, mentoring, health and wellness, and early childhood development, the Foundation promotes the preparation of succeeding generations of leaders.

Education - Higher Education Community Services

C. E. Boucher Memorial Scholarship

Seattle Foundation
Private
Benton County, Oregon, King County, Washington +2 more
US $3,000

Seattle Foundation is an agent of change, igniting powerful, rewarding philanthropy to make Greater Seattle a stronger, more vibrant community for all.

At Seattle Foundation, we believe that community is more than a place. It’s the shared understanding that our joy and well-being are tied to one another. Every day we work with nonprofits, philanthropists, and partners like you to strengthen community by igniting powerful philanthropy and advancing long-term solutions. Because it takes all of us to create a joyful region where every person can thrive.

C. E. Boucher Memorial Scholarship

This scholarship was established to honor and support engineering students studying at University of Washington, Washington State University, University of Oregon, and Oregon State University. This is a one-time scholarship for $3,000.

Engineering Education - Higher Education

ASEEES Summer Dissertation Writing Grant Program

Association for Slavic, East European, and Eurasian Studies (ASEEES)
Private
Albania, Armenia +27 more
Up to US $6,000

Association for Slavic, East European, and Eurasian Studies

The Association for Slavic, East European, and Eurasian Studies is a nonprofit, non-political international scholarly society whose mission is to advance knowledge and understanding of Central Asia, the Caucasus, Russia, and Eastern Europe within both regional and global contexts, while supporting scholars, students, and professionals in sharing research and fostering interdisciplinary collaboration. Its vision centers on sustaining intellectual vitality and global awareness of the region by serving as a leading hub for scholarship, dialogue, and professional development through publications, conventions, and academic exchange. The organization’s funding priorities focus on strengthening the field by providing financial support for research, dissertation completion, and scholarly dissemination; promoting teaching and mentorship; supporting early-career scholars; and encouraging interdisciplinary engagement and public awareness through programs, partnerships, and resources that enhance education and international studies.

ASEEES Summer Dissertation Writing Grant Program

The Summer Dissertation Writing Grant Program of the Association for Slavic, East European, and Eurasian Studies (ASEEES) reflects the organization’s broader mission of advancing knowledge and scholarship on the societies, cultures, and histories of Eastern Europe, Eurasia, and related regions by supporting emerging scholars during critical stages of their academic work. The program envisions strengthening the next generation of researchers by providing dedicated time and financial support for dissertation completion, particularly for students who do not have access to major research fellowships. Its funding priorities focus on enabling PhD candidates at U.S. institutions to concentrate on writing their dissertations over the summer months, supporting projects across disciplines within Slavic, East European, and Eurasian studies, and prioritizing applicants whose work contributes to the academic field but does not require significant in-region research or fieldwork, with grants intended to cover living support rather than tuition costs.

The summer dissertation writing grant program is directed at PhD students at US universities who do not qualify for the ASEEES Dissertation Research Grant because they do not intend to conduct significant research in the region as part of their dissertation research. Students may only receive ONE Summer Dissertation Writing Grant over the course of their graduate studies.

Humanities & Social Science Environment

AKN Family Scholarship

Arizona Community Foundation
Private
Arizona
Unspecified amount

Arizona Community Foundation

For more than four decades, the Arizona Community Foundation has worked in tandem with generous individuals, families, and organizations to address some of the biggest challenges facing our state.

Scholarships

In partnership with our generous donors, we award millions of dollars annually to help students achieve their educational goals. Through our online system, students complete one application and are matched with available scholarships, based on their eligibility requirements.

AKN Family Scholarship

The AKN Family Scholarship is a merit-based scholarship intended to support seniors graduating either from BASIS Charter Schools or Brophy College Preparatory (preferred, but not exclusive) whose college major will be a Humanities-related field.

Education - Higher Education Humanities & Social Science

Engineering Biological and Biomedical Systems (EBBS)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Engineering Biological and Biomedical Systems (EBBS) program, funded by the National Science Foundation (NSF), aims to advance our understanding of biological systems and improve human health through innovative engineering solutions. It supports research that combines mechanistic insights with experimental techniques to develop novel biomedical technologies, enhance biomanufacturing processes, and explore therapeutic applications. Projects focusing on engineering principles for biological responses and rehabilitation are encouraged, while drug design and clinical trials are outside the program's scope.
Engineering Bioengineering

Vermillion Area Community Foundation Grant

South Dakota Community Foundation
Private
Clay County, South Dakota
US $2,000 - US $4,000

South Dakota Community Foundation

As a statewide community foundation, we work with donors, nonprofits and community leaders to strengthen philanthropy in South Dakota every day.

Grants

The South Dakota Community Foundation offers an array of grants to help state nonprofits realize their dreams and continue investing in their communities. 

Vermillion Area Community Foundation Grant

The Vermillion Area Community Foundation was established in 2000 for the sole purpose of creating an endowed fund to build financial resources, that aren’t depleted each year and are forever and perpetual, to assist with capital projects that address community needs and that impact and enhance the quality of community life for residents of all ages.

South Dakota Community Foundation rules require VACF to fund tangible items rather than ongoing operating costs or salaries.

Community Services Human & Social Services Community Development & Revitalization

Social Justice Fund NW- Sponsorship

Social Justice Fund Northwest
Private
Idaho, Montana +3 more
US $1,000
The Social Justice Fund NW offers sponsorships to grassroots organizations in ID, MT, OR, WA, and WY, encouraging innovative projects often overlooked by traditional funders. Applicants must comply with specific requirements, including being within the designated region and ensuring events are accessible to the public. This initiative supports community-led efforts, particularly those led by Black, Indigenous, and people of color, fostering connections and amplifying collective action through diverse events.
Social Justice / Human Rights Art & Culture Community Services

Mary J. Mullarkey Scholarship

The Denver Foundation
Private
United States
US $1,000 - US $10,000
The Mary J. Mullarkey Scholarship, funded by The Denver Foundation, supports students of color, women, and LGBTQ+ individuals pursuing law degrees at accredited U.S. law schools. Eligible candidates must be graduating with an undergraduate degree from an accredited Colorado college or St. Norbert College, demonstrate financial need, and show academic excellence along with community contributions. One scholarship of up to $10,000 is awarded annually based on these criteria, promoting diversity in legal education.
Law Education - Higher Education

Diversity in Science- Graduate Diversity Enrichment Program

Burroughs Wellcome Fund
Private
North Carolina
US $5,000
The Graduate Diversity Enrichment Program (GDEP), funded by the Burroughs Wellcome Fund, aims to enhance diversity in science by providing $5,000 over two years to PhD students enrolled in North Carolina institutions. This initiative supports travel to conferences, research-related expenses, and promotes participation in peer networks. GDEP is designed for second to fifth-year PhD candidates in STEM fields who have demonstrated a commitment to equal access and opportunity in their academic and personal experiences.
Science STEM / STEAM Education

The Schneider Electric SkillPointe Scholarship

SKILLED Nation
Association/Society
United States
US $3,000
The Schneider Electric SkillPointe Scholarship aims to close the skills gap in America by providing $3,000 scholarships to individuals pursuing careers in building automation and related fields. Funded by the SkillPointe Foundation, this initiative is designed for students enrolled in relevant training programs who are passionate about energy and sustainability. With a proven success rate of 95% in training completion and 97% employment, this scholarship empowers workers to thrive in high-demand industries without requiring a four-year degree.
Energy Artificial Intelligence (AI)

National Science Foundation Fostering Interdisciplinary Networks to Develop Emergent and Responsive Solutions Foundry

National Science Foundation (NSF)
Federal Government
United States
US $50,000 - US $300,000
The National Science Foundation's FINDERS FOUNDRY program fosters collaboration among K-12 educators, technologists, and researchers to address challenges in learning and workforce development. By creating innovative, evidence-based solutions, the program enhances educational outcomes and prepares students for a digital future driven by Artificial Intelligence (AI). It emphasizes early exposure to AI, encouraging partnerships across various sectors to co-design responsive, technology-based solutions. The program includes phases for planning and development, aligning with national priorities.
Emerging Technology Development Artificial Intelligence (AI)

Deihl Humanities Grants

Greater Manhattan Community Foundation
Private
Riley County, Kansas
More than US $10,000
The Deihl Humanities Grants, established by the Greater Manhattan Community Foundation, aim to support community and public arts or humanities projects that enhance the quality of life in Manhattan and Riley County, Kansas. With a focus on proposals exceeding $10,000, these grants encourage initiatives that bring humanities to life through public programming, fostering community engagement and connections among individuals.
Humanities & Social Science Public / Community Art

Harrison Hooks Memorial Scholarship

Community Foundation of South Georgia
Private
Georgia (US state)
Unspecified amount

Who We Are

Founded in 1996, the Community Foundation of South Georgia is a 501(c)(3) nonprofit organization committed to making South Georgia a better place to live through effective philanthropy. We help individuals, families, nonprofit organizations and businesses establish and manage charitable funds that carry out their philanthropic interests. Serving a geographic area of 35 counties in South Georgia, we facilitate our donors’ charitable plans and goals by creating custom designed funds that meet their specific interests and ensure solid financial management and administration for each fund. 

Harrison Hooks Memorial Scholarship

For a graduating senior from a high school located in Thomas County, Georgia who is enrolled in or intends on enrolling in a college or university located in the state of Georgia and has attained at least a 3.0 GPA in high school. The award is based on Academics, Leadership Qualities, Extracurricular School Activities, Community Service and Financial Need.

Education - Higher Education Community Services

Professional Formation of Engineers

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Professional Formation of Engineers (PFE) initiative aims to enhance the engineering workforce through integrated research and education. It focuses on developing ethical engineers who can adapt to a changing technical landscape. PFE supports diverse training contexts, including formal education, internships, and community experiences, ensuring clear pathways into the profession. This initiative fosters collaboration among engineers, technical workers, and communities, enhancing the skills needed for global competition and technological advancement.
Engineering STEM / STEAM Education

Quiet Inspiration Award

Santa Fe Community Foundation
Private
Mora County, New Mexico, Rio Arriba County, New Mexico +2 more
Unspecified amount
The Quiet Inspiration Award, presented by the Santa Fe Community Foundation, recognizes nonprofits in northern New Mexico that have quietly made impactful contributions to their communities over at least three years. The award celebrates organizations that build trust and support among diverse groups while aligning with the Foundation's funding priorities. Nominations are open until May 8, 2026, inviting all community members to honor these vital contributors.
Community Services Economic Services & Development

Organizational Change in the Professional Formation of Engineers

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Organizational Change in the Professional Formation of Engineers (ENGINEER:OC) initiative promotes innovative research and activities aimed at transforming engineering education and workforce development. Supported by the National Science Foundation (NSF), it seeks to enhance access to quality engineering programs across diverse institutions. Projects may involve implementing new curricular innovations or adapting existing models to different contexts, ultimately advancing the professional formation of engineers and fostering inclusive educational pathways.
Engineering STEM / STEAM Education

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.