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Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability.
32,000+
Available grants
$8.25B
Total funding
$6K
Median grant
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OREF/Musculoskeletal Transplant Foundation Research Grant
Solicits investigator-initiated proposals focusing on research in the science of biologic – reconstruction, bone regeneration, transplantation - allografts, and including stem cells for graft transplantation.
Patrick J. Kiley / Houston AGC Scholarship
Benefiting employees, dependents of employees, and/or interns of AGC Houston member firms OR students involved in AGC Student Chapters.
Award Amounts
Multiple awards are given each year. Scholarship award amounts will vary for each selected scholarship recipient.
Pediatric Hidradenitis Suppurativa Challenge Grant
Hidradenitis suppurativa (HS) is a devastating chronic inflammatory disease that manifests as recurrent painful nodules under the skin in the intertriginous areas of the body. It is associated with significant impacts on quality of life, psychosocial well-being, and long-term health outcomes of patients as well as consequences for families and caregivers. HS is prevalent, affecting between 1 and 4% of the population beginning in adolescence and persisting into adulthood. Despite the impact of HS, it remains underdiagnosed, undertreated, and understudied particularly in the pediatric and adolescent populations. Contributing to this dynamic are unknowns related to a complex disease etiology, stigma associated with HS symptoms (e.g., sweating, itching, and scarring commonly in the genital region), and limited treatment options to date with even fewer available for children under the age of 12.
To address the needs of children and adolescents living with HS, the Pediatric Dermatology Research Alliance (PeDRA), HS Connect, and the HS Foundation are offering the 2026 Pediatric HS Challenge Grant to support an early-to-mid career investigator for a one-year project focused on a high-priority, patient-centric research topic.
Focus
Proposals should address one or more of the following high-priority research topics:
Funding:
Southeast Ohio Health and Wellness Foundation Fund community grants
The Southeast Ohio Health and Wellness Foundation Fund community grants program supports health and wellness activities in the fund’s eight-county service area, which includes Belmont, Coshocton, Guernsey, Harrison, Monroe, Muskingum, Noble and Tuscarawas counties.
About the fund
Established in 2023, the Southeast Ohio Health and Wellness Foundation Fund awards grants and scholarships that support health and wellness activities in the fund’s eight-county service area.
Grays Harbor Community Foundation
The Grays Harbor Community Foundation awards scholarships to local students for education after high school. The emphasis is on undergraduate studies at any* two or four year college or university and vocational/technical programs leading to a license or certification.
Bob and Elizabeth Preble Memorial Scholarship
Robert John ‘Bob’ Preble, 96, lifelong Aberdeen resident and local historian, passed away peacefully at his home-away-from-home on Hood Canal.
Bob was born June 13, 1921, in Aberdeen, Wash., to Walter and Mary (Briggs) Preble, the youngest of five children.
He was a 1939 graduate of Weatherwax High School and a 1943 graduate of Stanford University. Entering the U.S. Navy in 1943, he served at sea in anti-submarine warfare and left active duty with the Underwater Demolition Teams in 1946. He retired from the reserves as a Lt. Commander.
Born in Buenos Aires, Argentina, and raised in Rio Piedras, Puerto Rico, Liz Preble worked as a travel agent for Durney Travel and was herself a world traveler. With husband Bob she saw all of Europe and most of Latin America. She toured China, the Soviet Union, Japan, Thailand, and Indonesia. In Aberdeen, her home for 54 years, she was active in over a dozen community organizations, including St. Andrew’s Episcopal Church, the Friends of the Aberdeen Timberland Library, Chapter AK of the PEO Sisterhood, and the Pacific Peaks Girl Scouts Council. As patrons of the arts, Liz and Bob helped lead community efforts to install a George Tsutakawa fountain in front of Aberdeen’s City Hall and the bronze owl by Benny Bufano at the entrance to the Aberdeen Timberland Library.
The Bob and Elizabeth Preble Memorial Scholarship is open to all applicants who satisfy the general eligibility requirements. Each applicant should exhibit outstanding character, a proven work ethic, and the promise of useful citizenship. These more qualitative judgments will be based on the applicant’s personal essay, resume, transcripts and other information provided through the application form.
Service Club Alliance
The Service Club Alliance is a collaborative partnership between Midland area service clubs to coordinate efforts and simplify grantmaking for community organizations. The Service Club Alliance streamlines the grant process by using a common application for applicants who provide essential support to Midland County residents.
When an organization submits an application, it is automatically shared with all participating service clubs for review and consideration. This collective approach was established collaboratively by the participating clubs to ensure that community resources are allocated in the most effective and impactful way possible.
The Midland Area Community Foundation is not responsible for the grantmaking decisions made by the organizations below. We serve solely as the convenor of this alliance.
Clubs
Our grants typically range up to $5,000. Successful applicants must provide a project summary, including photos, within 12 months of completion.
There are two annual grant cycles.
Applicants who would like their request to be reviewed by Midland Rotary Foundation must have a Midland Noon Rotary Club member serve as a Sponsor to their request. The Sponsor must read the grant application ahead of submission. There is a field in the grant application form to include the Midland Noon Rotary Club sponsor name.
James T. Alvey Visionary Scorpion Scholarship
For a senior at Oakland Mills High School, who plans to attend a two- or four-year college or university and seeks to create a brighter future for all.
This scholarship is offered in memory of J.T. Alvey, OMHS Class of 2006. The award seeks to empower innovative thinkers and passionate creators by providing financial support to a student who has demonstrated exceptional creativity in their chosen field, whether it be art, design, writing, technology, or beyond. This scholarship is designed to support students who push the boundaries of creativity in their academic pursuits, artistic endeavors, and/or innovative projects.
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.43B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits?
Grants are most commonly $34,887.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.