Best Operating Grants for Nonprofits

The Victor E. Speas Foundation Grant offers support for organizations serving residents of Kansas City, Missouri. Established in 1947, the foundation prioritizes funding for medical care, research, and quality educational and health programming. Grant applications for general operating and program support are welcome, while capital support requests will not be considered. This initiative aims to enhance community health and educational services for those in need.

The Resident Research Preceptorship, funded by the Rheumatology Research Foundation, offers a $15,000 award for a three-month, full-time research experience. This initiative aims to inspire medical residents to explore careers in rheumatology research, enhancing the future workforce. By fostering mentorship and hands-on learning, the program supports the development of skilled rheumatology professionals, ultimately improving patient care for those with rheumatic diseases.

The Rheumatology Future Physician Scientist Award aims to enhance the research training of promising students pursuing MD or DO degrees, including those in combined programs. This award supports emerging physician-scientists, promoting their investigative careers in rheumatology. Grants of up to $30,000 per year are available for research projects aligned with the Rheumatology Research Foundation's mission, which focuses on improving patient health outcomes in rheumatic diseases.

The Health Professional Online Education Grant, offered by the Rheumatology Research Foundation, aims to enhance the skills of non-physician rheumatology professionals. By covering registration costs for the Advanced Rheumatology Course, this grant addresses the growing need for knowledgeable healthcare providers in rheumatology, ensuring better patient care for those with rheumatic diseases. This initiative supports the Foundation's mission to cultivate a robust workforce and improve health outcomes for patients.

The Four Cedars Environmental Fund, supported by the Boreal Waters Community Foundation, offers financial assistance for programs that protect and educate about the unique natural resources of the western Lake Superior watershed. Eligible applicants include charitable organizations and those serving specific counties in Wisconsin and Minnesota. The fund aims to enrich local environmental initiatives through capital requests, start-up costs, and technical support, fostering sustainable practices within the community.

The Mentored Nurse Practitioner/Physician Assistant Award for Workforce Expansion, funded by the Rheumatology Research Foundation, aims to increase the number of rheumatology healthcare providers across the U.S. This initiative addresses the growing demand for specialists, particularly in underserved areas. With an award amount of $25,000 for one year, it equips new NP/PAs with essential skills and knowledge needed for successful integration into rheumatology practices, enhancing patient access to quality care.

Community Foundation of Greater Des Moines

The Community Foundation of Greater Des Moines improves quality of life for all by promoting charitable giving, connecting donors with causes they care about and providing leadership on important community issues…we’re simply better together.

Enhance Henry County Community Foundation

The mission of the Enhance Henry County Community Foundation is to foster private giving, strengthen service providers and improve the conditions of the county. To these ends, it will promote endowment building, community, grantmaking, organizational collaboration, and public leadership for the benefit of Henry County.

Enhance Henry County Community Foundation Grants

The Enhance Henry County Community Foundation will provide grants to improve life in Henry County, Iowa. We want to help develop all our communities into places where people want to live, as well as to benefit rural areas of the county. Areas of Foundation giving are: arts & culture, community affairs & development, education, environmental protection, health, historic preservation and human services.

Grants are available to 501(c)3 organizations and government entities serving Henry County. Grant selections are made in an effort to create a better quality of life for people in Henry County. The local governing committee reviews the applications from charitable organizations serving their community.

The Mildred B. Price Nursing Scholarship, established by William B. Price in honor of his mother, supports aspiring nursing students in Indiana. This scholarship aims to empower residents of Grant, Hamilton, Knox, Madison, Pulaski, Starke, or White Counties. Eligible applicants must demonstrate financial need and maintain a GPA of 2.5 or higher while pursuing a nursing degree at any Indiana college or university. This initiative fosters equitable opportunities in the nursing profession.

The National Days of Service Funding: MLK Day Project Grant Competition, administered by ServeOhio, aims to support community service projects for Martin Luther King Jr. Day on January 19, 2026. Grants will fund initiatives that enhance community assets, engage youth volunteers, and include educational components. Eligible applicants are non-profit and public organizations in Ohio. Projects should promote collaboration and can occur throughout January 2026, with funding restrictions on volunteer support costs.

The Children, Youth, and Families Grant supports programs fostering equity and resilience among youth in Colorado. By partnering with community leaders, the initiative aims to create safe, nurturing environments for children, helping them thrive. Funding is available in areas such as basic needs, emotional well-being, behavioral health, and economic stability. Organizations can apply if they serve the Colorado community and adhere to specific eligibility criteria. This grant is essential for promoting long-term prosperity and equity for families.

The ESHPF Disaster Relief Assistance Grant Program, administered by the Virginia Department of Historic Resources, has received $2,000,000 from the NPS to document historic resources in areas affected by Hurricane Helene. This program aims to support community-driven efforts for surveying architectural and archaeological sites in 37 localities across Virginia. Eligible projects may include preservation planning and nominations for the National Register of Historic Places, ensuring the protection and recognition of Virginia's rich cultural heritage.

Community Foundation of Greater Des Moines

The Community Foundation of Greater Des Moines improves quality of life for all by promoting charitable giving, connecting donors with causes they care about and providing leadership on important community issues…we’re simply better together. 

Foundation of Greater Plymouth County

The Foundation of Greater Plymouth County was formed in 2005 to coordinate and provide philanthropic support for community betterment projects in Plymouth County. The CFGPC is an affiliate of the Iowa Community Affiliate Network, a collaboration of the Community Foundation of Greater Des Moines and the Iowa Area Development Group Community Foundation. Each year the Foundation makes grant awards to worthwhile projects located in the county that are identified through this community grant application process.

Foundation of Greater Plymouth County Grants

Grants are available to 501(c)3 organizations and government entities serving Plymouth County. Grant selections are made in an effort to create a better quality of life for people in Plymouth County. The local governing committee reviews the applications from charitable organizations serving their community. Our areas of emphasis include:

• Children, Youth, and Families
• Community Betterment-Neighborhoods and Community Development
• Health and Human Services
• Education
• Environment
• Arts and Culture

The MSCRF Commercialization Program aims to advance human stem cell research for the prevention and treatment of diseases. It supports Maryland-based companies in developing technologies with commercial potential, offering up to $500,000 in funding for collaborative projects. The program encourages partnerships between public and private sectors to enhance research and technology development, emphasizing the importance of stem cell therapies in addressing critical health challenges.

Crime Victim Assistance Grants

The mission of the Department of Crime Victim Assistance Grants (DCVAG) is to enhance South Carolina’s capacity to assist crime victims and to provide leadership in the promotion of justice and healing. Through grant funding, victims can receive services including:

• Victim Advocacy
• Counseling
• Residential Shelter
• Forensic Interviews and Forensic Nurse Examination
• Emergency Assistance

Victims of Crime Act (VOCA)

DCVAG is responsible for the administration of four grant programs including the Victims of Crime Act (VOCA), a 1984-Public Law 98-473 established the Victims of Crime Act (VOCA) - Federal Fines, Fees, and Assessments

The primary purpose of VOCA is to support the provision of direct services to victims of violent crime. The program goal is to provide federal funding through grant awards to certified private non-profit organizations and public/government agencies for projects that will provide, enhance, improve, and expand direct services to victims of violent crime. 

According to the 2016 VOCA Program Rule, direct services or services to victims of crime are defined as those efforts that (1) respond to the emotional, psychological, and physical needs of crime victims, (2) assist victims to stabilize their lives after victimization, (3) assist victims to understand and participate in the criminal justice system, or (4) restore a measure of safety and security for the victim.

Funding cannot be used for the investigation of crimes or collection of evidence to further the prosecution of crimes.

The Providers Clinical Support System – Universities program aims to equip graduate-level health professional students with the necessary skills to understand, identify, intervene, and treat patients with substance use disorders. By focusing on practical training and comprehensive education, this initiative prepares future practitioners to effectively address the challenges associated with substance misuse, ensuring they are well-prepared upon obtaining their licenses.

The Steven Berkeley Marine Conservation Fellowship, established by the American Fisheries Society in 2007, honors a dedicated fisheries scientist. This $15,000 award supports graduate students engaged in thesis research on marine conservation topics. Applicants must be enrolled in a North American university's M.S. or Ph.D. program and be AFS members in good standing. The fellowship encourages innovative research addressing various conservation issues, not limited to fisheries.

The DISC5 Awards, funded by the California Institute for Regenerative Medicine, aim to support innovative research in stem cell technologies that enhance patient care. Grants of up to $1.5 million for individual projects and $3 million for team efforts are available, with a project duration of up to three years. These awards encourage collaboration and focus on addressing critical knowledge gaps in regenerative medicine, promoting diversity and inclusivity in research.

The Highmark Foundation's School Grants Program offers up to $7,500 for schools in Pennsylvania and West Virginia to enhance children's health and well-being. The program supports initiatives focusing on basic needs, environmental health, mental and social health, physical health, and school nursing support. By empowering schools with these resources, the foundation aims to create nurturing environments that foster healthy habits and improve educational outcomes for all students.

The Katherine P. Douglas Scholarship, offered by the Community Foundation of Elmira-Corning and the Finger Lakes, supports high school seniors and adult learners from Steuben, Chemung, and Schuyler counties pursuing degrees in math, science, health sciences, nursing, or public health at Corning Community College. Applicants must be in the top 15% of their graduating class and provide three recommendations. This scholarship aims to eliminate financial barriers to education, fostering access to higher learning.

The Stanford Medicine Children’s Health Center for IBD and Celiac Disease offers funding for postdoctoral fellows and instructors to conduct innovative research focused on pediatric IBD and celiac disease. This initiative aims to nurture future researchers and prepare them for independent funding opportunities. Eligible research includes basic, clinical, epidemiological, and health policy studies related to maternal and child health. Funding supports substantial salary and benefits, ensuring commitment to impactful research in this critical area.

The Vital Farms Local Impact Grantmaking Program, in partnership with the Community Foundation of the Ozarks, aims to enhance the lives of farmers' communities across Missouri. With $125,000 available, the program focuses on projects related to animal welfare, food access, youth education, and agriculture. Eligible applicants include 501(c)(3) organizations and IRS-approved entities. The initiative emphasizes ethical food practices and community support, ensuring that funds are allocated to projects that foster positive impact in local communities.

The Stanford Children's Health Center for IBD and Celiac Disease offers Intramural Seed Grants to promote innovative research in pediatric diseases. This program supports high-risk, high-reward projects, encouraging multi-PI collaborations across disciplines. Awards of up to $100,000 per year for two years are available, aimed at generating preliminary data for future funding applications. Eligible applicants include Stanford faculty holding specific university positions. Proposals should focus on advancing understanding of pediatric IBD and celiac disease through various research approaches.

The Ralph W. Shrader Graduate Scholarship offers $3,000 to full-time graduate students in STEM-related fields at accredited U.S. institutions. Applicants must be U.S. citizens, enrolled in their second semester, and maintain a GPA of 3.5 or higher. The scholarship supports tuition and course-related expenses, encouraging students with financial needs to further their education. Notably, the expected graduation date cannot coincide with the award year, ensuring students are committed to their studies.

The Constantine Youth Advisory Council Fund, managed by the Sturgis Area Community Foundation, supports youth-related programs and projects in the Constantine area. With a commitment to enhancing community quality of life, this fund offers one competitive grant cycle each year exclusively through application. Eligible recipients include tax-exempt organizations and government entities serving St. Joseph County residents. This initiative plays a vital role in empowering local youth and enriching their opportunities for growth.

The Texas Talent Connection Grant Program, led by Governor Abbott, aims to foster innovation in workforce development. This initiative supports exemplary training projects that enhance job placement, wage increases, and job retention. Eligible partnerships include local workforce boards and educational institutions, which can apply for funding up to $350,000 annually for projects addressing workforce populations with special needs. Applicants must reapply yearly, with no guarantee of continued funding.

The Dr. Chao-ying & Sue Wu Early Learning Scholarship, established by the Chuckanut Health Foundation in 2022, honors the vital contributions of Dr. Chao-ying and Sue Wu to the health and education of Whatcom youth. This scholarship aims to eliminate financial barriers for local students pursuing careers in early learning, reflecting the Foundation's commitment to investing in community potential and fostering opportunities for future generations.

The Mid-Illinois Communications Association Scholarship supports rising juniors, seniors, and graduate students pursuing communications-related fields such as journalism, public relations, and marketing. Applicants must be from Central Illinois or attend a Central Illinois college, and they should be direct descendants of U.S. Service Members. This scholarship fosters educational growth for those committed to serving their communities through effective communication.