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Best Operating Grants for Nonprofits

Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability.

32,000+

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$8.25B

Total funding

$6K

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32,000+ grants
$8.25B total
$6K median

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Edward P. Suchecki Family Scholarship

Grand Haven Area Community Foundation
Private
United States
Unspecified amount
The Edward P. Suchecki Family Scholarship, established by the Grand Haven Area Community Foundation, supports local high school senior athletes pursuing a business career. Named after Ed Suchecki, a dedicated coach and businessman who valued education, this scholarship prioritizes financial need and favors football and golf players. Applicants must submit their transcripts and other required documents. This initiative aims to empower young athletes to achieve their educational goals.
Education - Higher Education Educational Access & Equity Sports & Athletics +3 more

PLTW Gateway - New Program (Intel Foundation)

Project Lead the Way inc.
Private
Arizona, New Mexico +1 more
US $20,000

About PLTW Gateway

PLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine. Through explorations of skilled trades, coding and robotics, flight and space, human body systems, and more, PLTW Gateway fuels students’ passion for discovery. As they engage in hands-on, collaborative problem solving focused on real-world challenges, students use and stretch their imaginations in brand-new ways that connect their learning to life.

Through this partnership, Intel Foundation has committed funds to support PLTW grants to schools interested in starting or expanding PLTW programs beginning in the 2027-2028 academic year.

Program Requirements

  • Grantee must offer at least one PLTW Gateway unit in the 2027-2028 academic year and must offer one additional unit in the 2028-2029 academic year (two different units in two years).
  • Grantee may implement any PLTW Gateway units of their choosing.
  • Grantee must complete two years of Grant reporting. 

Grant Award and Distribution Schedule:

  • Total Award: $20,000
    • 2027-2028: $10,000
    • 2028-2029: $10,000
Workforce Preparation & Job Readiness Career / College Preparation STEM / STEAM Education

James Knott Memorial Scholarship

Albuquerque Community Foundation
Private
United States
Up to US $1,000
The James Knott Memorial Scholarship, established by the New Mexico Manufactured Housing Association, supports graduating high school seniors residing in manufactured homes. Awards of up to $1,000 are given annually to students with a minimum GPA of 3.0 who attend a nonprofit or public educational institution full-time. Applicants must provide proof of residency, a written statement of financial need, and a reference from a teacher or counselor. This scholarship aims to empower students to achieve their educational goals.
Education - Higher Education Vocational & Trade Education Career / College Preparation +2 more

PLTW Gateway - Program Expansion (Intel Foundation)

Project Lead the Way inc.
Private
Arizona, New Mexico +1 more
US $10,000

About PLTW GatewayPLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine. Through explorations of skilled trades, coding and robotics, flight and space, human body systems, and more, PLTW Gateway fuels students’ passion for discovery. As they engage in hands-on, collaborative problem solving focused on real-world challenges, students use and stretch their imaginations in brand-new ways that connect their learning to life.Through this partnership, Intel Foundation has committed funds to support PLTW grants to schools interested in starting or expanding PLTW programs beginning in the 2027-2028 academic year.Program Requirements

  • Grantee must use their grant funds to expand their existing PLTW Gateway program. 
    • Example : Expansion activities include but are not limited to adding an additional PLTW Gateway unit not previously offered, and/or adding additional class periods of an existing PLTW Gateway unit previously offered, and/or training additional teachers in a PLTW Gateway unit for the 2027-2028 academic year.

    • Grantee must complete one year of grant reporting. 

    Grant Award and Distribution Schedule:

    • Total Award: $10,000
      • 2027-2028: $10,000
    Workforce Preparation & Job Readiness Career / College Preparation STEM / STEAM Education

    DPS&C Emergency and Transitional Housing Program

    Louisiana Department of Public Safety and Corrections (DPS&C)
    State/Local Government
    Louisiana
    Up to US $5,000

    Department of Public Safety and Corrections

    The Department of Public Safety and Corrections consists of three main divisions:

    • Corrections Services oversees the custody and care of adults in prison and includes adults under probation and parole supervision.
    • Public Safety Services encompasses Louisiana State Police, the Office of Motor Vehicles, the State Fire Marshal’s Office and Highway Safety Commission.
    • Youth Service oversees the juvenile justice system in Louisiana.

    Emergency and Transitional Housing Program

    The Department of Public Safety and Corrections (DPS&C) is seeking housing providers to join the Emergency and Transitional Housing (ETH) program to provide participants with stable short-term housing and food access on a per diem basis.

    The Emergency and Transitional Housing (ETH) program provides limited funding to increase access to short-term housing for individuals at risk of homelessness and who are under the supervision of the Division of Probation and Parole or have recently been released from state incarceration. The ETH program aims to provide emergency and/or transitional housing to stabilize the reentry process until longer-term housing can be found, improving their chances of having a successful reentry experience.

    This program shall be funded by a portion of the savings allocated to the Department of Public Safety and Corrections (DPS&C) for reinvestment in programs and services that reduce prison admissions and recidivism.

    Reentry Services Supportive Housing & Shelters Food Access & Hunger

    Transportation Research and Policy

    Arnold Ventures
    Private
    United States
    Up to US $200,000

    Transportation Research and Policy

    Arnold Ventures (AV) is a philanthropy dedicated to improving the lives of all Americans through evidence-based solutions that maximize opportunity and minimize injustice.

    The Infrastructure team has been investing in efforts to build better, faster, and lower-cost infrastructure with a focus on housing, energy, and transportation. For transportation, we are investing in policymaking and research that tackles the inefficiencies that make U.S. transportation infrastructure so difficult and expensive to build. 

    Purpose

    Transportation policy represents an avenue for improving the systems moving people, goods, and services. The Infrastructure team is seeking proposals evaluating the effectiveness and/or benefits of existing transportation or transportation-adjacent policies on outcomes for communities in the United States.

    Eligible Projects and Topic Areas of Interest

    This Request for Proposals (RFP) aims to bolster the knowledge base of potentially effective policies, programs, and interventions by funding efforts that align with key AV Infrastructure policy areas.

    AV is primarily focused on traditional surface transportation — road and public transit — but is open to proposals in aviation, maritime, passenger and freight rail, trucking, and more.

    We seek proposals for: 1) research, expanded data sets, or analysis; 2) administrative or legislative policy reforms at the federal, state, or local level; or 3) models of effective implementation including proposals for implementing agencies to partner with researchers or program evaluators to conduct baseline and post-intervention research on implementation effectiveness that will advance the knowledge base and provide illustrative examples within, but not limited to, the following topic areas:

    • Transportation Capital Investment Reform. Evaluating how capital funding is prioritized and selected at the federal, state, or regional level, including discretionary grant programs and formula-based funding. What reforms could ensure projects deliver higher public returns?
    • Cost Estimation, Oversight, and Accountability. Why do major transportation projects frequently exceed budgets and timelines, and how can we identify strategies to improve transparency, cost realism, and performance oversight?
    • Access in Mobility Outcomes. Measuring how current transportation investments affect access to jobs, services, and economic opportunities for workers and families, and what policy changes could improve access.
    • Performance-Based Project Selection. How can public agencies shift from current, politically driven allocations to datadriven, performance-based decision-making on capital project selections?
    • Institutional Barriers to Reform. What organizational, legal, or procedural hurdles prevent DOTs and MPOs from adopting better practices (e.g., outcome-based planning, integrated land use/transportation policy)?
    • Permitting and Permit Reform. How do current local, state, and federal permitting practices affect project cost, quality, timeline, and other concerns?
    • Intergovernmental Dynamics. How do federal, state, and local funding structures and requirements enable or constrain effective transportation investment? What governance structures would improve outcomes when it comes to transportation planning and project delivery?
    • Data Sets and Root Causes of High Delivery Costs. Expanded data sets on unit costs and/or research illuminating the root causes of why transportation and transit projects cost so much and take so long to deliver. What policy and practice changes could manage project delivery risks and improve the likelihood that projects will be delivered on s chedule and on budget?
    • Domestic Content. How do Buy America and domestic content requirements affect the cost, speed, innovation, and effectiveness of transportation infrastructure projects?
    • Procurement Process. How do current procurement practices affect project cost, quality, innovation, and accountability — and what policy and regulatory reforms could improve outcomes?
    • Other. AV also welcomes innovative proposals on other transportation issues that align with our mission.

    These research, policy development, and implementation proposals can be relevant to federal surface transportation reauthorization legislation or federal administrative changes; state reforms to Departments of Transportation; and/or local-level reforms relevant either to regional transportation agencies, transit agencies, or municipal governments.

    Public Policy Public Transportation & Mass Transit Systems Public Infrastructure

    Rural Health Transformation Program Funding - Rural Federally Qualified Health Center

    Minnesota Department of Health
    State/Local Government
    Minnesota
    Up to US $1,900,000

    Minnesota Department of Health

    Mission: Protecting, maintaining and improving the health of all Minnesotans.

    Vision: The vision of MDH is for health equity in Minnesota, where all communities are thriving and all people have what they need to be healthy.

    Rural Health Transformation Program Funding 

    The federal Rural Health Transformation Program (RHTP) was created by H.R.1 (Section 71401 of Public Law 119-21) on July 4, 2025. It is a federal initiative to help states support rural communities in improving health care access, quality, and outcomes by transforming the health care delivery ecosystem. The RHTP focuses on promoting innovation, strategic partnerships, infrastructure development, and workforce investment in rural communities. Minnesota has outlined their initiatives online (learn more about Minnesota's Rural Health Transformation Program).

    Grant recipients will select activities from broad RHTP initiatives designed to advance the overarching goals of improving health outcomes and access to care for rural Minnesotans, sustainably expanding the rural health care workforce, strengthening partnerships between providers to expand service delivery in rural communities, and stabilizing rural provider financial health through strategic investments. 

    Entity Type: Federally Qualified Health Centers (FQHCs)

    Estimated Number of Awards: 5

    Estimated Maximum Award in Budget Period 1: $1,900,000

    Applicants may request up to the maximum award.

    Community Health Education Preventative Healthcare Health Disparities & Social Determinants of Health +1 more

    Rural Health Transformation Program Funding - Rural Tribal Nations

    Minnesota Department of Health
    State/Local Government
    Minnesota
    US $150,000 - US $807,996

    Minnesota Department of Health

    Mission: Protecting, maintaining and improving the health of all Minnesotans.

    Vision: The vision of MDH is for health equity in Minnesota, where all communities are thriving and all people have what they need to be healthy.

    Rural Health Transformation Program Funding 

    The federal Rural Health Transformation Program (RHTP) was created by H.R.1 (Section 71401 of Public Law 119-21) on July 4, 2025. It is a federal initiative to help states support rural communities in improving health care access, quality, and outcomes by transforming the health care delivery ecosystem. The RHTP focuses on promoting innovation, strategic partnerships, infrastructure development, and workforce investment in rural communities. Minnesota has outlined their initiatives online (learn more about Minnesota's Rural Health Transformation Program).

    Grant recipients will select activities from broad RHTP initiatives designed to advance the overarching goals of improving health outcomes and access to care for rural Minnesotans, sustainably expanding the rural health care workforce, strengthening partnerships between providers to expand service delivery in rural communities, and stabilizing rural provider financial health through strategic investments. 

    Entity Type: Tribal Nations (Bois Forte Band of Chippewa; Fond du Lac Band of Lake Superior Chippewa; Grand Portage Band of Lake Superior Chippewa; Leech Lake Band of Ojibwe; Lower Sioux Indian Community; Mille Lacs Band of Ojibwe; Oyate (Upper Sioux); Prairie Island Indian Community; Red Lake Nation; White Earth Nation)

    Estimated Number of Awards: 10

    Estimated Maximum Award in Budget Period 1: $150,000 - $807,996

    Applicants may request up to the maximum award.

    Community Health Education Preventative Healthcare Health Disparities & Social Determinants of Health +1 more

    Veterans and Heroes Agribusiness Pitch Competition

    West Virginia Department of Agriculture
    State/Local Government
    West Virginia
    Unspecified amount

    Veterans and Heroes to Agriculture Program

    The Department of Agriculture developed the Veterans and Heroes to Agriculture Program to integrate veterans into the field of agriculture, and support veterans currently working in agriculture. These programs may include, but are not limited to, using post-mine land for agricultural development, promoting high tunnel crops and production, expanding the apiary industry, developing cottage industries, exploring niche crops, raising more livestock, increasing the aquaculture industry and helping veterans promote their agricultural products through farmers markets and cooperatives.

    Veterans and Heroes Agribusiness Pitch Competition

    The WVDA Agribusiness Pitch Competition aims to encourage law enforcement, fire fighters, emergency medical service, first responders, veterans, active-duty military, and/or their spouses and family to engage in agriculture, and agribusiness ventures. The initiative also aims to ensure the continuous creation of investible ideas and start up originators that will contribute to enhancing the Department of Agriculture’s food security objectives and economic growth.

    Agriculture Agricultural Economics Food Security

    Robin Hood Foundation Grant

    The Robin Hood Foundation
    Private
    Bronx County, New York, Kings County, New York +3 more
    Unspecified amount
    The Robin Hood Foundation Grant supports 501(c)(3) organizations in New York City focused on alleviating poverty. This strategic grantmaking initiative partners with promising organizations to create long-term solutions for economic mobility across various life stages. Eligible entities are encouraged to express their interest, as funding opportunities are not available through unsolicited proposals. By fostering collaboration in the community, the Foundation aims to maximize its impact on low-income New Yorkers.
    Youth Services Child Welfare Services Family Services +5 more

    100WomenStrong Competitive Grants

    Community Foundation for Loudoun and Northern Fauquier Counties
    Private
    Loudoun County, Virginia
    Unspecified amount
    100WomenStrong Grants, established in 2008, empower community members to impact Loudoun County through collective giving. This grant cycle prioritizes projects addressing shelter, health, hunger, and education. Eligible applicants must be 501(c)(3) nonprofits with two years of operation, focusing on local needs. Grants support operational and project funding from May 2025 to April 2026, emphasizing innovative solutions and community benefits, ensuring responsible stewardship of resources.
    Food Access & Hunger Supportive Housing & Shelters Education +1 more

    Focus Grants

    Outer Banks Community Foundation
    Private
    Carteret County, North Carolina, Currituck County, North Carolina +2 more
    Unspecified amount
    Focus Grants provide funding requests up to $50,000 aimed at addressing critical needs, particularly in healthcare access, affordable housing, and childcare solutions. These grants are available to qualifying 501c3 charities and government agencies, with a preference for projects that may require multi-year support. The Outer Banks Community Foundation, a private funder, supports these initiatives to enhance community welfare and improve lives.
    Equitable & Affordable Housing Child Care Services Health Care Access & Delivery

    Whitaker Foundation - Arts & Parks Grants

    Mr and Mrs Lyndon C Whitaker Charitable Foundation
    Private
    Bond County, Illinois, Calhoun County, Illinois +20 more
    Unspecified amount
    The Whitaker Foundation, established in 1975, supports arts and parks initiatives in St. Louis, Missouri. By funding arts organizations and park projects, it enriches community life through creativity and shared spaces. Eligible applicants must have 501(c)(3) status and provide free public programming. The foundation does not fund playgrounds, sports leagues, or individual grants, ensuring support is directed towards impactful community projects that promote relaxation, beauty, and celebration.
    Parks & Public Spaces Art History Visual Arts +4 more

    Black Mountain-Swannanoa Valley Endowment Fund

    The Community Foundation of Western North Carolina
    Private
    Buncombe County, North Carolina
    US $2,500 - US $10,000
    The Black Mountain-Swannanoa Valley Endowment Fund supports charitable organizations in the Swannanoa Valley, focusing on health, education, and wellness. Grants range from $2,500 to $10,000 for innovative projects and programs. Eligible organizations include 501(c)(3) entities and governmental bodies within the Owen School District. The Fund emphasizes projects that can be completed within a year but prioritizes requests for ongoing support less favorably. Endorsements are required if another organization benefits.
    Health & Medicine Education Art & Culture +3 more

    GCCF: GladYAC Educator Mini-Grant Program

    Midland Area Community Foundation
    Private
    Gladwin County, Michigan
    Up to US $250
    The GladYAC Educator Mini-Grant Program, funded by the Gladwin County Community Foundation, aims to inspire educators in Gladwin County to create unique classroom projects that engage students with diverse learning styles. This program supports interdisciplinary and active-learning initiatives that enhance the curriculum and promote real-life applications. Eligible applicants include K-12 educators from both public and non-public schools, and projects must be completed within the current academic year.
    Education - High School Education - Middle School Education - Elementary School +1 more

    Breast Cancer Community Education Grants for ONS Chapters

    Oncology Nursing Society
    Private
    United States
    Up to US $1,000
    The Breast Cancer Community Education Grants, funded by the Oncology Nursing Foundation through AstraZeneca HealthCare Foundation, aim to enhance breast cancer awareness through nurse-led community education programs. Grants of up to $1,000 are available to ONS Chapters in the U.S., enabling them to implement impactful educational initiatives. Eligible activities must focus on community outreach and education, fostering a broader understanding of breast cancer.
    Nursing Breast Cancer Community Health Education

    GMAR Youth Foundation Grant

    Greater Milwaukee Association of Realtors
    Association/Society
    Milwaukee County, Wisconsin, Ozaukee County, Wisconsin +2 more
    Unspecified amount
    The GMAR Youth Foundation Grant, managed by the Greater Milwaukee Association of REALTORS®, aims to enhance the welfare of children and young people up to 25 years old. Established in 1951, this foundation focuses on supporting educational, social, and artistic initiatives in the Metro Milwaukee Area. Nonprofit organizations classified as 501(c)(3) are encouraged to apply, provided they demonstrate a significant impact on local youth development. Grants are awarded for one-year periods.
    Child Welfare Services Youth Development & Leadership Youth Involvement in the Arts +2 more

    Wolverine Worldwide Foundation Grant

    Wolverine Worldwide Foundation
    Private
    Michigan
    Unspecified amount
    The Wolverine Worldwide Foundation Grant aims to enhance community well-being through dedicated support in areas such as health, education, and environmental sustainability. Founded in 1959, the foundation focuses on promoting healthy lifestyles, diversifying trades, and advancing community initiatives. By engaging with local organizations, it fosters inclusive opportunities across West Michigan, Boston, Richmond, and London, ultimately striving for a positive impact in the communities it serves.
    Health & Medicine Human & Social Services Education +5 more

    JACF Grants

    JA Community Foundation
    Private
    United States
    US $2,500 - US $50,000
    The JA Community Foundation focuses on funding solutions that address the needs of the Japanese American and broader Asian American communities. They prioritize programs that enhance senior health, promote history, arts, culture, and support youth. Eligible applicants must be registered 501c3 organizations and can apply from all 50 states. However, organizations with open grants cannot submit new applications until their current grants are closed.
    Senior Services Aging / Gerontology Asian Art +2 more

    Jewel-Osco Foundation

    The Albertsons Companies Foundation
    Corporate
    Clinton County, Iowa, Illinois +2 more
    US $2,500 - US $25,000
    The Jewel-Osco Foundation supports nonprofit organizations that enhance neighborhood welfare, focusing on areas like hunger, youth education, and veterans. Grants typically range from $2,500 to $25,000 for first-time applicants. The foundation promotes inclusivity and requires a nondiscrimination policy from applicants. It does not fund individuals, religious organizations for religious purposes, or fundraising events, ensuring funds are directed towards impactful programs. Applications are reviewed monthly, with a response timeframe of 4-6 weeks.
    Food Access & Hunger Military & Veterans Services Disability Care & Services +3 more

    Jeannette F. Schlobach Grant Program

    Community Foundations of the Hudson Valley
    Private
    Dutchess County, New York
    Up to US $20,000
    The Jeannette F. Schlobach Grant Program provides essential support to nonprofit organizations serving residents of Dutchess County, NY, affected by poverty. It focuses on enhancing economic stability, health, and educational opportunities through effective programs such as case management, housing services, and health access. Eligible organizations include 501(c)(3) nonprofits and faith-based groups. The grant encourages innovative solutions while supporting existing programs, ensuring a lasting impact on the community.
    Employment Services Health Care Access & Delivery Animal Welfare - Domestic Animals & Pets +2 more

    Diabetes Funding Opportunities: Diabetes Support Program - Walk With Ease Project

    Montana Department of Public Health and Human Services
    State/Local Government
    Montana
    US $5,000

    Montana Department of Public Health and Human Services

    At the Montana Department of Public Health and Human Services (DPHHS), we are dedicated to our mission of serving Montanans in their communities to improve health, safety, well-being, and empower independence. As the largest executive branch agency in the state, our broad reach allows us to provide essential, community-based support where and when it matters most. Our DPHHS team is passionate about improving our clients’ lives and helping them build a more secure and independent future.

    Funding Opportunities for Healthcare Professionals

    Join us in a funded project and improve patient care, clinical outcomes, and staff knowledge. DPHHS has a wide variety of available grant opportunities for health improvement that fit any clinic or hospital work schedule. Interested in more than one? We can work with health systems to create an outline of activities to align grants and receive additional funding. 

    Diabetes Funding Opportunities: Family Healthy Weight Program Implementation; DSMES-Accreditation Recognition; Chronic Kidney Disease (CKD) QI Project; Diabetes Retinopathy QI Project; Diabetes Support Program- Walk With Ease Project; Access to Care Project; Diabetes Support Program Implementation.

    Diabetes Support Program- Walk With Ease Project

    Increase access to and participation in complementary diabetes support programs for their patients with or at risk for developing diabetes utilizing the Walk with Ease program.

    Epidemiology & Public Health Diabetes Healthy Habits & Behaviors

    DCCF: Small Project Grants

    Decatur County Community Foundation Inc.
    Private
    Decatur County, Indiana
    Up to US $2,000
    The DCCF Small Project Grants offer funding of up to $1,500 for organizations aiming to implement impactful small-scale projects in Decatur County. The foundation supports initiatives in various areas such as community development, education, health, and the arts. Eligible applicants include 501(c)(3) nonprofits, governmental agencies, and educational institutions, provided their projects benefit the local community. This grant encourages innovative projects that foster community participation and significant positive change.
    Civic Affairs Community Development & Revitalization Education +8 more

    DCCF: Large Project Grants

    Decatur County Community Foundation Inc.
    Private
    Decatur County, Indiana
    US $2,000 - US $20,000
    The DCCF Large Project Grants offer funding between $1,500 and $15,000 to support innovative projects that address significant needs in Decatur County. Priorities include initiatives that foster community engagement and can leverage additional funding. Eligible applicants must be 501(c)(3) nonprofits or governmental agencies serving Decatur residents. The foundation discourages funding for individuals, political activities, and projects solely reliant on DCCF support. Grants are awarded three times a year, emphasizing impactful community contributions.
    Civic Affairs Community Development & Revitalization Education +8 more

    Modesto Rotary Club Foundation Community Grant

    Modesto Rotary Club Foundation
    Private
    Stanislaus County, California
    Unspecified amount

    The mission of The Modesto Rotary Club Foundation (MRCF) is to support local organizations and projects through charitable contributions. 

    Grants

    The Modesto Rotary Club Foundation’s aim is to help organizations stretch and have bigger impact in Modesto.

    The Modesto Rotary Club Foundation will support game-changing work across all program areas, and we especially encourage initiatives that support:

    • Health and wellness
    • Youth enrichment
    • Community beautification
    • Assist vulnerable families

    Successful applications will demonstrate community need, and yield tangible and measurable results. Funds are available for program development/expansion, innovation, technology and equipment. 

    Award amounts will be based on:

    • Proposed project budget
    • Scope of project
    • Capacity of organization to successfully execute the project

    Wellness & Healthy Living Health Disparities & Social Determinants of Health Youth Development & Leadership +2 more

    Clinical Repurposing Research to Impact Veterans/Military

    Cures Within Reach
    Private
    United States
    Up to US $75,000

    Cures Within Reach

    Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

    Clinical Repurposing Research to Impact US Veterans/Military

    This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

    Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

    Mental Health & Psychiatric Diseases Post-Traumatic Stress Disorder Brain Injuries +2 more

    Diabetes Funding Opportunities: Diabetes Retinopathy QI Project

    Montana Department of Public Health and Human Services
    State/Local Government
    Montana
    US $5,000

    Montana Department of Public Health and Human Services

    At the Montana Department of Public Health and Human Services (DPHHS), we are dedicated to our mission of serving Montanans in their communities to improve health, safety, well-being, and empower independence. As the largest executive branch agency in the state, our broad reach allows us to provide essential, community-based support where and when it matters most. Our DPHHS team is passionate about improving our clients’ lives and helping them build a more secure and independent future.

    Funding Opportunities for Healthcare Professionals

    Join us in a funded project and improve patient care, clinical outcomes, and staff knowledge. DPHHS has a wide variety of available grant opportunities for health improvement that fit any clinic or hospital work schedule. Interested in more than one? We can work with health systems to create an outline of activities to align grants and receive additional funding. 

    Diabetes Funding Opportunities: Family Healthy Weight Program Implementation; DSMES-Accreditation Recognition; Chronic Kidney Disease (CKD) QI Project; Diabetes Retinopathy QI Project; Diabetes Support Program- Walk With Ease Project; Access to Care Project; Diabetes Support Program Implementation.

    Diabetes Retinopathy QI Project

    Provide funding opportunities for healthcare professionals to work on a quality improvement project to increase access and improve screening for the early detection of diabetes retinopathy (DR).

    In addition to the funding amount, this grant includes the possibility of a retinopathy camera if needed.

    Epidemiology & Public Health Eye Diseases & Disorders Diabetes

    Operating Grants for Nonprofits Highlights

    Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.


    Search Instrumentl's Operating Grants Database


    Explore 8,000+ funding opportunities for operational support, with $3.43B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.

    Last updated: October 5, 2026. Next update: November 1, 2026.

    Grant Insights : Operating Grants for Nonprofits

    Grant Availability

    How common are grants in this category?

    Quite common — grants in this category are more prevalent than in others.

    8,000+ Operating grants for nonprofits grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

    3,000+ Operating grants for nonprofits over $25K in average grant size

    3,000+ Operating grants for nonprofits over $50K in average grant size

    1,000+ Operating grants for nonprofits supporting general operating expenses

    7,000+ Operating grants for nonprofits supporting programs / projects

    600+ Grants on Instrumentl focused on Food Access & Hunger

    3,000+ Grants on Instrumentl focused on Education

    Grant Deadline Distribution

    Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?

    Most grants are due in the first quarter.

    Q1
    29.8%
    Q2
    23.8%
    Q3
    23.9%
    Q4
    22.6%

    Typical Funding Amounts

    What's the typical grant amount funded for Operating Grants for Nonprofits?

    Grants are most commonly $34,887.

    $0 $0 Min.
    $34,887 $34.9 K Median
    $655,609 $655.6 K Average
    $188,250,000 $188.3 M Max.

    Frequently asked questions

    Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.

    Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

    Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.

    Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

    Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.

    To improve the chances of getting operating grants, nonprofits should:

    • Showcase past impact – Use data and real-world examples to prove how your organization has already made a difference.
    • Prove how you align with funder priorities – Research what funders care about and explain how your nonprofit’s mission fits within their goals.
    • Prove financial stability – Funders want to support organizations that can manage funds responsibly and have a solid sustainability plan for the long-term.
    • Emphasize lasting growth – Describe how operating funds will help your nonprofit expand its reach, strengthen programs, and increase its overall impact.

    For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.

    Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

    Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.