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Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability.
33,000+
Available grants
$9.00B
Total funding
$6K
Median grant
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About
Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.
Mae and Wilbur Fulmer Scholarship ($2,000)
This renewable scholarship supports students who will graduate from a high school located in Chapin, South Carolina.
Conference Grants and Research Training Awards
Objective
The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate world class science to deliver transformative regenerative medicine treatments in an equitable manner to a diverse California and world. In September 2024, CIRM released its Strategic Allocation Framework (SAF), a structured and data-driven process guiding how the Agency prioritizes its funding and programs.
To this end, CIRM will periodically issue Requests for Applications (RFA) to support valuable mission-specific conferences that complement CIRM’s Programs and align with the Strategic Allocation Framework. Recipients of these conference grants are expected to collaborate with CIRM to fulfill a specific need as defined in the RFA.
EDUC8 Awards: Umbrella for CIRM Bridges and COMPASS Funding Opportunities
Objective:
Prepare undergraduate through master’s level students for career-entry opportunities in regenerative medicine by identifying and supporting untapped talent and producing well-trained, adaptable, and committed professionals for the regenerative medicine workforce.
Scope:
EDUC8 enables training programs that provide relevant coursework, instill key competencies, and support paid, hands-on internships to produce technically skilled individuals who can deliver on CIRM’s mission. An EDUC8 Award may be structured to support a COMPASS Path, a Bridges Path, or both (Dual Path). All paths include patient engagement, community outreach, and strategic mentoring practices for efficient transition of trainees to careers in the life sciences. Innovative recruitment and retention strategies will broaden the participation and perspectives of Californians in the regenerative medicine workfoce.
Department of Behavioral Health
The Department of Behavioral Health provides prevention, intervention and treatment services and supports for children, youth and adults with mental and/or substance use disorders including emergency psychiatric care and community-based outpatient and residential services.
DBH serves eligible adults, children and youth and their families through a network of community based providers and unique government delivered services. It operates Saint Elizabeths Hospital—the District’s inpatient psychiatric facility.
Hospital -Based Peers Support Services
The Government of the District of Columbia, Department of Behavioral Health, Adult Services Administration is soliciting applications from qualified organizations to implement the Hospital-Based Peer Support Services program under the District of Columbia Opioid Response (DCOR) grant. The DCOR grant, guided by LIVE.LONG.DC.(LLDC), is focused on increasing access to medications for opioid use disorder (MOUD) treatment, reducing unmet treatment needs, and reducing opioid overdose-related deaths in the District of Columbia through the provision of prevention, harm reduction, treatment, and recovery support services (RSS) to individuals with stimulant use disorder (STUD) and opioid use disorder (OUD).
Target Population
The target population is individuals who have OUD and/or STUD that receive care in a participating hospital within the District of Columbia. Individuals may be in the hospital ED or an inpatient unit for OUD/STUD-related reasons (e.g., overdose or injection-related infection) or for any other reason.
Community Foundation of the Quincy Area
My Community Foundation (also known as The Community Foundation Serving West Central Illinois & Northeast Missouri) is a tax-exempt 501(c)(3) nonprofit organization dedicated to improving quality of life in the communities it serves by connecting compassionate donors with meaningful causes. The foundation works with individuals, families, businesses, and nonprofit partners to gather charitable contributions, grow those funds through professional investment strategies, and grant the earnings in ways that address local needs now and into the future. It builds and manages permanent endowments tailored to donors’ goals, ensuring their philanthropic visions—whether honoring a loved one, establishing a legacy, or supporting community needs—are realized. Serving a 12-county region across West Central Illinois and Northeast Missouri, the foundation acts as a steward of charitable assets, helping donors make a lasting impact through customized giving opportunities, community grants, and strategic support for nonprofit organizations.
George & Sharen Borrowman Agriculture Scholarship Fund
George & Sharen Borrowman Agriculture Scholarship Fund supports former students or graduates of John Wood Community College who are continuing their education at an accredited four-year college or university. Eligible applicants must be entering their junior or senior year and pursuing a bachelor’s degree in an agriculture-related field. Application criteria and additional requirements are administered through the school, and interested students should contact their school guidance counselor for guidance. Scholarships are awarded annually in the spring.
Mission
To improve the health and healthcare of all residents residing within Stanislaus and Merced counties (19 specific cities and Zip codes) by increasing access to various healthcare services and educating people about healthy lifestyle decisions. Our objective is to dramatically improve the quality of life within the greater LHE community by bringing together resources, expertise, vision and the belief we can – and will – make a difference.
Grant Information
Legacy Health Endowment grants shall be distributed solely and exclusively to support nonprofit, tax-exempt charitable healthcare facilities and clinics. The grants shall be used to fund direct healthcare services, wellness programs, health research, health education and public/private partnerships formed to improve the health of the residents in the LHE community.
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.34B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits?
Grants are most commonly $32,500.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.